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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5991_Библиотеки_им_академика_М_И_Перельмана
.pdf
24
Metals in Medicine, Volume 1
2
mol
because they are not NP (0.8–3.5 m
2
g
). Hunt
3
F
27
COOH)
51
56
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Recent Advancements in Nanoporous Metal Foams for Biomedical Applications
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-
57
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materials, have been developed to address the “stress-shielding” issue.
57
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Metals in Medicine, Volume 1
2
mol
(70 m
2
g
), strong monolithicity, pores in the
51
-
results imply that the innovative composite materials might serve as the
58
)y Cu
)
y
Cu
30
Cu
70
precursor to become coarser, leading to an increase in ligament
y
Cu
precursors
implant applications.
59
quantities is demonstrated by the microarc oxidation (MAO) technology,
60
created a
biodegradable porous metal employing an anodic coating on AZ
31
Mg alloy
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Recent Advancements in Nanoporous Metal Foams for Biomedical Applications
27
-
measuring around 1.5 GPa and 5.0 MPa, respectively.
-
ings, coated 316L stainless steel has better bioactivity than uncoated 316L
stainless steel.
over others. Bencina et al.
62
-
NPG demonstrated good biocompatibility by not being poisonous to cells or
https://t.me/med1917
28
Metals in Medicine, Volume 1
medications are more likely to access the target tissue or target cells because
-
enabling medications to be delivered in a targeted manner to certain tissues
variable, drug loading capacity, membrane permeability, and drug targeting
63
iron metal and the amino terephthalate ligand MIL-101-NH
2
-Fe.
64
-
ment that makes it easier to carry biological substances and medications.
2
SO
4
drug release rate.
65
such as doxorubicin have been inserted into porous silicon holes. For drug
pores determines their capacity.
66
2
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Recent Advancements in Nanoporous Metal Foams for Biomedical Applications
29
(SDDSs), immediate drug delivery systems, targeted drug delivery systems,
and systems that respond to stimuli (CDDSs). By including the appropriate
2
, and Cl, mesoporous
67
-
by Keskin et al.
68
additional pores in the prototype MOF, Ni-MOF-74. An ideal combination
-
-
ated by encapsulating 4.6 mol g
69
In contrast to other nanocarriers that commonly release the drug molecules
systems. It is interesting to note that the noncovalent strategy has a high
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Metals in Medicine, Volume 1
51
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silicon nanoparticles, core-shell nanoparticles, porous silicon, and MOF are
among the materials used.
70
-
nancies. Fe
3
O
4
-UiO
66
MOFs have been used to deliver an anticancer agent
(doxorubicin) and have improved biopharmaceutical qualities including
regulated drug-release properties up to 40 days, superior anticancer activity
reported using Mn-containing nano-MOFs, namely, Mn(1,4-BDC)(H
2
O)
2
and Mn
3
2
(H
2
O)
6
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Recent Advancements in Nanoporous Metal Foams for Biomedical Applications
31
66
Researchers have looked at using MOF in photodynamic therapy as a
energy light in the excited state, results in reactive oxygen species (ROS).
-
chlorine-based nano-MOFs (DBC-UiO) have many superior photophysical
-
tosis and immunogenic cell death against colon cancer.
66
Sensory systems employ various membrane-bound protein pores to recog-
2
sensors.
71,72
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Metals in Medicine, Volume 1
-
and other compounds.
66
Hu et al.
74
-
75
be brought on by aberrant DA levels. Yil et al.
76
DA biosensor by electrodepositing palladium (Pd) nanoparticles onto a
-
suggested dopamine biosensor had good selectivity, stability, repeatability,
and exceptional durability in aqueous conditions, NP anodic alumina is also
77
reaching implanted cells or medication release mechanisms. Encapsulation
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Recent Advancements in Nanoporous Metal Foams for Biomedical Applications
33
bigger immune system chemicals such as immunoglobulin. Desai et al.
78,79
-
80
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Escherichia
coli and Gram-positive Staphylococcus aureus bacteria, using cobalt ions
-
tions, colony counting results demonstrate the exceptionally high antibac-
against S. aureus.
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