Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5471_Библиотеки_им_академика_М_И_Перельмана
.pdf
124
Metals in Medicine, Volume 1
4
technology-savvy (Fig. 6.1).
Source
5
In 1995, Yaghi et al.
6
introduced
-
7
separations,
8–10
11
catalysis,
12–17
sensing,
18–23
bioimaging,
24,25
energy storage,
26–30
and
https://t.me/med1917
Metal–Organic Framework in Bioimaging and Biosensing Application
125
drug delivery .
31,32
the ability to quench.
33,34
-
cence properties that can sensitively respond to their local environment or
visiting species
35
36,37
38
-
39
Addition-
3
-
3
) 2H
2
37
https://t.me/med1917
126
Metals in Medicine, Volume 1
TABLE 6.1 MOFs Application in Biosensing.
Ligand structure Ligand Cation Metal–organic frame Surface Area Pore Sensing Target MOFs role References
abbreviation (Metal) work formula (m2/g) size
H3Cmdcp Cu2+ 9.7 Fluorescence
Quenching
16.6
Dy3+ – –
H3CbdcpBr Zn2+ – – Fluorescence
n Quenching
H2dcbbBr Cu2+ – – Fluorescence
Quenching
https://t.me/med1917
Metal–Organic Framework in Bioimaging and Biosensing Application
127
Ligand structure Ligand
abbreviation
Cation
(Metal)
Metal–organic frame
work formula
Surface Area
(m2/g)
Pore
size
Sensing T arget MOFs role References
FA Fe3+
(MIL-88A)
5–7 DNA Fluorescence
Quenching
Zr4+
(PCN-222)
32
13 Phosphoprotein
TABLE 6.1
(Continued)
https://t.me/med1917
128
Metals in Medicine, Volume 1
40
include GO and MoS2.
44
MOFs such as MIL-101,
45
36,46
UiO-66-NH2 are highly sensi-
tive and are able to react distinctly to changes in luminescence caused by
2
O
2
2
3
2
H
2
-
47
aptamers.
48
49
In the past,
prenatal studies, has been carried out through laborious, extensive, and
complex instrumentation requiring methods such as electrophoretic sepa-
mutation detection.
50,51
https://t.me/med1917
Metal–Organic Framework in Bioimaging and Biosensing Application
129
2
dtoaCu to detect
2
O
2
CL-Aptasensors.
Source
52
53
reliable and reproducible biosensors using MOFs, certain challenges must
-
https://t.me/med1917
130
Metals in Medicine, Volume 1
-
tially replace conventional and laborious methods.
54
in various MOF composites
55,56
Zang and colleagues developed a phos-
-
2
biological macromolecules.
shell nanocomposites (CSNCPs).
50,57
Lin et al. demonstrated gelatinase-A
2
57
-
https://t.me/med1917
Metal–Organic Framework in Bioimaging and Biosensing Application
131
58
Wang and colleagues developed a bio-probe
2
(DMF)0.5(H
2
O)
3
(H
4
-
pH conditions due to the porous structure, metal-based nodes, and organic
59
Yang and his colleagues have developed a MOFs-in-nanochannels elec-
2
60
On the other hand, Hou and his colleagues have
HP-PCN-224(Fe).
61
62
Hou and colleagues developed a
63
glucose oxidation to produce H
2
O
2
H
2
O
2
conducted by Wei and colleagues.
64
https://t.me/med1917
132
Metals in Medicine, Volume 1
2
O
2
activity level.
63
such as reactive oxygen species (ROS) (O
2
-, OH, RO, H
2
O
2
). For example,
2
65
2
O
2
2
O
2
, Fe
2
+ is
3
66
All reactive oxygen species exhibit high oxidative activity
method).
67,68
-
2
3
2
H
2
3
3
2
O
2
in biological
samples using either electrochemical or colorimetric methods.
69,70
Chen and
-
https://t.me/med1917
Metal–Organic Framework in Bioimaging and Biosensing Application
133
70
6
trap these drugs either by supramolecular heptameric hydrogen bonding or
71
2
+,
72
a Zn-based MOF, NH
2
2
2
–BDC)
2
2
3
73
-
2
2
O
2
.
74
https://t.me/med1917
Соседние файлы в папке Библиотека им академика М.И. Перельмана