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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5705_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •About the Editor
- •Contents
- •Contributors
- •1.1.4 Components of niosome
- •1.1.5 Factors affecting niosomes
- •Preface
- •Abstract
- •1.1 Introduction
- •1.1.1 Why niosome?
- •1.1.2 Advantages of niosome
- •1.1.3 Structure of niosome
- •1.2 Applications of niosome
- •1.2.2 Niosomes for the delivery of therapeutics
- •1.2.3 Niosomes in biomedical applications
- •1.3 Conclusions and future prospects
- •Keywords
- •References
- •Abstract
- •2.1 Introduction
- •2.2 Conclusions
- •Acknowledgments
- •Keywords
- •References
- •Abstract
- •3.1 Introduction
- •3.2.1 Parameters involved in electrospinning process
- •3.2.2 Biomaterials for electrospinning
- •3.3 Electrospun nanofibers as drug delivery systems
- •3.3.1 Blending electrospinning
- •3.3.2 Emulsion electrospinning
- •3.3.3 Coaxial electrospinning
- •3.3.4 Surface modifications
- •3.4 Electrospun nanofibers for tissue engineering
- •3.4.1 Electrospun nanofibers for hard tissue engineering
- •3.5 Cancer diagnosis and therapy
- •3.6 Concluding remarks and future perspectives
- •Keywords
- •References
- •4. Natural Biocarriers for Brain Targeting
- •Abstract
- •4.1 Introduction
- •4.1.1 Central nervous system
- •4.2 Biocarriers
- •4.2.1 Carbohydrates carriers
- •4.2.2 Protein carriers
- •4.2.3 Exosomes
- •4.3 Conclusions and perspectives
- •Keywords
- •References
- •Abstract
- •5.1 Introduction
- •5.2 Synthesis of graphene family nanomaterials
- •5.2.1 Graphene synthesis
- •5.2.2 GO and rGO Syntheses
- •5.2.3 GQd synthesis
- •5.4 Drug delivery and biomedical applications
- •5.4.1 Drug delivery
- •5.4.2 Gene delivery
- •5.4.3 Bioimaging
- •5.4.4 Photothermal therapy
- •5.4.5 Tissue engineering
- •5.5 Summary and future prospect
- •Keywords
- •References
- •6. Nanotechnology in Gene Delivery
- •Abstract
- •6.1 Introduction
- •6.2 Gene delivery
- •6.3 Nanotechnology in gene delivery
- •Keywords
- •References
- •Abstract
- •7.1 Introduction
- •7.2 Additive manufacturing in pharmacology
- •7.2.1 Extrusion-based 3D printing techniques
- •7.2.2 Stereolithography
- •7.2.3 Selective laser sintering
- •7.2.4 Binder jet printing
- •7.3 Most common polymers
- •7.3.1 Natural polymers
- •7.3.2 Synthetic polymers
- •7.3.2.5 Polyvinylpyrrolidone
- •7.4 Common 3D-printed dosage forms
- •7.4.1 Scaffolds
- •7.4.2 Tablets
- •Keywords
- •References
- •7.4.3 Microneedles
- •7.4.4 Capsule
- •7.4.5 Films
- •7.5 Main factors in drug delivery
- •7.5.1 Nature of polymers
- •7.5.2 Matrix permeability
- •7.5.3 Polymer blends
- •7.5.4 Specific surface area
- •7.5.5 Infill density and patterns
- •7.5.6 Pores
- •7.5.7 Cross-linking
- •7.5.8 Coating
- •7.5.9 Core/shell and multicompartment
- •7.6 Final considerations and future perspectives
- •Abstract
- •8.1 Introduction
- •8.2.1 Polymer solution concentration and viscosity
- •8.2.2 Molecular weight of polymer
- •8.2.3 Surface tension
- •8.2.4 Electrical conductivity
- •8.2.5 Applied voltage
- •8.2.6 Feed rate/flow rate
- •8.2.7 Temperature and humidity
- •8.3 Method of preparation for nanofibers
- •8.3.1 Electrospinning
- •8.3.2 Self-assembly
- •8.3.3 Phase separation
- •8.3.4 Drawing of nanofibers
- •8.3.5 Template synthesis
- •8.4 Biomedical applications of nanofibers
- •8.4.1 Wound dressing
- •8.4.2 Tissue engineering
- •8.4.3 In cancer therapy
- •8.4.4 Miscellaneous
- •8.5 Drug delivery application
- •8.5.1 Antihypertensive drug
- •8.5.2 Antimicrobial drug
- •8.5.3 Growth hormone
- •8.5.4 Miscellaneous
- •8.6 Conclusion
- •Keywords
- •References
- •Abstract
- •9.1 Introduction
- •9.2 Tissue engineering
- •9.3 Nanotechnology
- •9.4 Polymeric scaffolds in tissue engineering
- •9.5 Challenges
- •Keywords
- •References
- •Abstract
- •10.1 Introduction
- •10.2 Ideal properties of bioceramics
- •10.2.1 Mechanical property
- •10.2.2 Porosity, pore size, and shape
- •10.2.3 Biocompatibility and biodegradability
- •10.2.4 Osteoconductivity and osseointegrity
- •10.3 Bioceramics in orthopedic applications
- •10.4 Bioceramics in maxillofacial surgery
- •10.5 Bioceramic in drug delivery applications
- •10.6 Doped bioceramic in biomedical application
- •10.7 Conclusions
- •10.8 Future direction
- •Acknowledgments
- •Keywords
- •References
- •Index

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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
10.5 BIOCERAMIC IN DRUG DELIVERY APPLICATIONS
-
mesoporous silica particles are implanted in bone tissues, a physiological
-
2001). Among the protein delivery, Album has got special attention due to
maintaining osmotic pressure, (ii) maintaining blood pH, and (iii) Revers-

Bioceramics System for Biomedical Application
309
-
-
-
(Wang et al., 2013), methotrexate (Rosenholm et al., 2010), anti-herceptin
(Milgroom et al., 2014) and many more (Fig. 10.3). It has been observed
that tumor mass is having more dense collagen layer outside the mass
-
(Villegas et al., 2015).

310
Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
FIGURE 10.3
10.6 DOPED BIOCERAMIC IN BIOMEDICAL APPLICATION
-
3
and MnO
2
-
2+
, Mg
2+
, Mn
2+
,
Co
2+
, Sr
2+
, and Fe
3+
2+

Bioceramics System for Biomedical Application
311
al., 2021). Cerium, terbium, erbium, europium, lanthanum, and dysprosium
et al., 2015).
2+
-
Mg
2+
-doped mesoporous bioactive nanoparticles have been studied incorpo-
or silver nanoparticles has been investigated by many researchers to overcome
-
2+
-
Cu
2+
2+

312
Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
as its antibacterial and osteogenic properties are concerned. Sr
2+
then used
related studies on Sr
2+
10.7 CONCLUSIONS
more than ten years. For more than 10 years, BG and several CPC have been
surgery has been to get a positive biological response despite the restric-
several composites and multilayer systems are being developed and tested.
10.8 FUTURE DIRECTION

Bioceramics System for Biomedical Application
313
-
remedying
ACKNOWLEDGMENTS
KEYWORDS
• bioceramics
• orthopedic applications
• maxillofacial surgery
• drug delivery
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