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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5705_Библиотеки_им_академика_М_И_Перельмана.pdf
258
Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
Xu et al., 2008).
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organs and is able to achieve the required drug concentration around the
produce comparatively better cell death percentage and tumor inhibition rate
8.4.4 MISCELLANEOUS
Nanofiber Technology in Biomedical Applications
259
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al., 2006).
8.5 DRUG DELIVERY APPLICATION
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
TABLE 8.2 Drug Delivery Application.
Drug classification System name Drug used Polymer used References
Antihypertensive drug
Valsartan Polyvinylpyrrolidone
K-90 (PVP K-90)
2021
Irbesartan PVP K-90 Adeli, 2015
Biodegradable composite
Captopril and
Poly(l-lactic acid) (PLLA) Wei et al., 2011
PVP K-90 and l-arginine
2021
Antimicrobial drug PVA and poly(ethylene
oxide)
2012
Pullulan
PCL Monteiro et al., 2017
PVA, CS, and hyaluronic
acid
Hosseini et al., 2021
Buccal adhesive double-
hGH Eudragit and CS Choi et al., 2016
Miscellaneous Curcumin and
Almond gum and PVA
2019
Resveratrol CS and gellan Rostami et al., 2019
CS Behbood et al., 2018
Indomethacin Eudragit S and Eudragit
RS
Akhgari et al., 2017
Nanofiber Technology in Biomedical Applications
261
8.5.1 ANTIHYPERTENSIVE DRUG
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
drugs. So, all the results conclude that the compound antihypertensive drugs
8.5.2 ANTIMICROBIAL DRUG
to exhibit antimicrobial activity against the Escherichia coli, P. aeruginosa,
Aspergillus niger, Penicillium notatum, and Aspergillus flavus. So, this
antimicrobial agent by the electrospinning technology using pullulan
(21–25)
Pal
E. coli
Nanofiber Technology in Biomedical Applications
263
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Aggre-
gatibacter actinomycetemcomitans and Porphyromonas gingivalis and they
delivery (Monteiro et al., 2017).
8.5.3 GROWTH HORMONE
and hyaluronic acid polymers due to their biodegradability , biocompatibility ,
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hormones (Hosseini et al., 2021).
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
materials (Choi et al., 2016).
8.5.4 MISCELLANEOUS
R
2
value greater than 0.9176. So, it
and Nasirpour, 2019).
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Nanofiber Technology in Biomedical Applications
265
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8.6 CONCLUSION
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tissue regeneration. Recently, several studies have reported its applications
KEYWORDS
• nanofiber
• electrospun
• drug delivery
• biopolymer
• wound healing
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Advances in Pharmaceutical Technology for Drug Delivery Systems (PTDDS), Volume 2
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