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364
Metals in Medicine, Volume 2
     
  
            
      





76,77

     -

11.10 PALLADIUM NANOPARTICLES FOR ANTITUMOR THERAPY
       
          


78





   
79
 
80
causes DNA damage, protein damage, and lipid peroxidation by triggering

FIGURE 11.3 
https://t.me/med1917
Toxicological Effect of Platinum and Palladium Nanoparticles
365
11.11 CONCLUSION



   

-

      
         

     

KEYWORDS
• palladium nanoparticles
• plant models
• animal models
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368
Metals in Medicine, Volume 2
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Action. Eur. J. Pharmacol. 2014, 740, 364–378.
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     Molecules 2015, 20
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M. Palladium-Mediated Intracellular Chemistry. Nat. Chem. 2011, 3 (3), 239–243.
80.           
Indian J. Clin. Biochem. 2015, 30,
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Metals in Medicine, Volume 2: Metallic Nanoparticles for Biomedical Applications.
Sonali Sundram, Rishabha Malviya, and GSN Koteswara Rao
© 2025 Apple Academic Press, Inc. Co-published with CRC Press (Taylor & Francis)
Utilization of Palladium in Photothermal
Therapy of Cancer
SATHISH KUMAR KONIDALA
1
, BHARATH SINGH PADYA
1
,
GSN KOTESWARA RAO
2
, and, ROJA RANI BUDHA
2
1
Department of Pharmaceutical Sciences, School of Biotechnology and


2
Shobhaben Pratapbhai Patel School of Pharmacy & Technology

India
CHAPTER 12
ABSTRACT
       -




photothermal hyperthermia materials has promising potential. Photothermal



           

       -
    
      
highly porous nanostructures. Enhanced drug loading and controlled drug
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Metals in Medicine, Volume 2
release are achieved in tumor microenvironments by repetitive laser ablation
    

         


          
       

     

studies indicate that Pd-NFs had a positive repair impact on diabetic mouse


12.1 INTRODUCTION
            
people.
1
Common cancer therapies, such as invasive surgery, radiation

       
2–4



-
           



inhibits radiation-induced DNA repair, and associated treatment by drugs
and radioactive agents in cancer patients is clearly superior to chemo- or
radiotherapy alone.
5,6
      

7
radio-
therapy,
8
and immunotherapy.
9

modalities concurrently and correctly in order to completely exert the syner-
-

       
https://t.me/med1917
Utilization of Palladium in Photothermal Therapy of Cancer
373
-

10–12
   

(NPs),
13
    
14
and nanostructures prepared by
carbon.
15

          

16,17
or chemo-
therapeutic medicines.
18–21


       
       
131
 

0.052 cm
3
g


       
release in tumor microenvironments is precisely regulated by repetitive

polymer poly(N-isopropylacrylamide)-co-poly(acrylamide) (pNIPAAm-co-
pAAm).
22
  
131
   

23,24
Without any
separation, the
131


131





131


potential to be used in combination treatment that is guided by imaging.
12.2 PREPARATION OF PHPD-NPS
     
(H
2

          
     
25
Pd-NPs have become

2
reduction reaction. Alkenes and aromatic nitro
compounds can be hydrogenated to generate alkanes and amino compounds
by using Pd-NPs trapped in aluminum oxyhydroxide as catalysts.
26
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