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134 A. H. Schoenfeld
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mode results in a smaller volume of tissue irradiated and a lower intensity of scattered radiation. The x-ray beam always should be collimated to the smallest size needed for viewing to minimize scatter to the operator and im­prove visualization.
The size of the patient as a determining factor in pa­tient dose cannot be controlled. It is obvious that a larger patient attenuates a greater fraction of the incident x-ray beam; thus, the kVp and exposure rate must increase to maintain the proper image brightness.
The use of cut film and digital subtraction angiog­raphic (DSA) techniques during interventional proce­dures also contributes to the total effective dose equiva­lent the patient will receive. One study of ten patients undergoing cerebral angiography revealed that, on aver­age, 67% of the effective dose equivalent to the patient was due to fluoroscopy with 26% contributed by cut film and 7% by DSA.
9
■ Factors Affecting the Dose
to the Radiologist
Exposure to the radiologist in the interventional suite is due to scattered radiation resulting mainly from the Compton interaction and also from leakage radiation. All x-ray units are required to have a protective tube housing that limits the leakage radiation to 100 mR/hr at 1 m when the unit is operating at the maximum technique factors for continous radiation production.
The intensity of the scatter radiation levels in the room depends on the exposure rate incident on the patient and the volume of tissue in the beam. As mentioned, the amount of scattered radiation at a distance of 1 m from the patient is approximately 0.1% of the incident beam intensity.
If the area of the x-ray beam entering the patient is increased, the fraction of the beam that is scattered in­creases approximately in direct proportion. Thus, it is clearly advantageous to collimate the beam as closely as possible to minimize the scatter component, which will decrease the exposure to the operator and improve im­age quality.
The patient’s size affects operator exposure because increases in attenuation of the x-ray beam as a result of greater patient diameter will result in higher mA and kVp values with more scattered photons and a greater degree of stray radiation to the radiologist.
The location of the x-ray tube also can affect the stray radiation dose levels received by the radiologist and other personnel in the room. In general, it is preferable to position the x-ray tube underneath the table rather than above it, as most of the scatter is produced near the side of the patient first intercepted by the beam. If the tube is placed in the lateral position, the radiologist will be ex-
TABLE 12-3.
Minimize total fluoroscopy time. Keep image intensifier as close as possible to patient. Do not use high level mode, if available, unless absolutely
necessary. Keep x-ray tube underneath patient whenever possible. Try to maintain distance from x-ray tube and patient. Always wear lead apron and film badge(s). Try to limit use of magnification mode. Collimate x-ray beam to area of interest. Keep hands out of primary beam as much as possible. If kV is manually adjusted, use higher kV (ⱖ75) and lower mA
techniques. Use the last image hold and pulsed fluoroscopy if available.
Summary of techniques to minimize radiation exposure to patient and operator
posed to lower radiation levels near the image intensifier rather than near the x-ray tube.
■ Potential for Skin Injuries to the Patient
Although fluoroscopically guided interventional proce­dures are often the treatment of choice for critically ill pa­tients, there is some potential for radiation induced in-
10
jury.
Certain interventional procedures may require long fluoroscopic exposure times along with recording of images, which may leadto entrance skin doses of 2 Gy (200 rad) or more with subsequent skin injuries. During an in­terval of approximately 4 years, the FDA received reports of skin injuries to 26 patients, including erythema, moist desquamation, and skin necrosis.
11
The procedues result­ing in skin injuriesincluded radiofrequency cardiac cathe­ter ablation, catheter placement for chemotherapy, transjugular interhepatic portosystemic shunt placement, coronary angioplasty, renal angioplasty, multiple hepatic or biliary procedures,and percutaneous cholangiography followed by multipleembolization procedures.
The FDA
12
recommends that information be recorded for patients that might receive a threshold dose to the skin of 1 Gy (100 rad) or more, including identification of those areas of the patient’s skin that may receive the dose threshold and an estimateof thedose receivedor informa­tion that would allow estimation of thedose to those areas. The dose to the skin may be estimated by direct measure­ment with placement of dosimeters on the skin during the procedure. Alternatively, the radiation exposure rates may be measured for the particular x-ray system and the skin dose may be calculated if the system geometry and the technique factors are recorded, such as kVp, mA, total exposure time during fluoroscopy and kVp, mAs per im­age, and the total number of images during digital or conventional image acquisition. Although the FDA rec­ommends recording information for dose estimation in cases that may approach the threshold of 1 Gy, it is pru­dent to record this information for all interventional cases.
Radiation Protection
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135
■ Summary
A summary of techniques to minimize radiation exposure to the patient and the operator is given in Table 12-3.
REFERENCES
1. Limitation of exposure to ionizing radiation. NCRP Report no. 116. Bethesda, MD: National Council on Radiation Protection and Mea­surements, 1993.
2. Use of personal monitors to estimate effective dose equivalent and effective dose to workers for external exposure to low-LET radia­tion. NCRP Report no. 122. Bethesda, MD: National Council on Radiation Protection and Measurements, 1995.
3. Niklason LT, Marx MV, Chan H-P. Interventional radiologists: occu­pational radiation doses and risks. Radiology 1993;187:729–733.
4. Medical x-ray, electron beam and gamma-ray protection for ener­gies up to 50 MeV (equipment design, performance and use). NCRP Report no. 102. Bethesda, MD: National Council on Radia­tion Protection and Measurements, 1989.
5. Wagner LK, Mulhern BS. Radiation-attenuating surgical gloves: effects of scatter and secondary electron production. Radiology 1996;200:45–48.
6. Agarwal SK, Friesen EJ, Huddleston AL, et al. The effectiveness of glass lenses in reducing exposure to the eyes. Radiology 1978; 129:810–811.
7. Tidwell A, Brahmavar S, Breton R, et al. Radiation exposures in pulsed fluoroscopy systems: patient and physician. Med Phys 1994;21:943. (abst.)
8. Norbash AM, Busick D, Marks MP. Techniques for reducing inter­ventional neuroradiologic skin dose: tube position rotation and supplemental beam filtration. AJNR Am J Neuroradiol 1996;17: 41–49.
9. Feygelman VM, Huda W, Peters KR. Effective dose equivalent to patients udergoing cerebral angiography. AJNR Am J Neuroradiol 1992;13:845–849.
10. Wagner LK, Eifel PJ, Geise RA. Potential biological effects following high x-ray dose interventional procedures. J Vasc Inter vent Radiol 1994;5:71–84.
11. Shope TB. Radiation-induced skin injuries from fluoroscopy. Ra- diographics 1996;16:1195–1199.
12. Recording information in the patient’s medical record that identi­fies the potential for serious x-ray induced skin injuries following fluoroscopically guided procedures. Rockville, MD: Food and Drug Administration (FDA), Department of Health and Human Ser v­ices, September 15, 1995.
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M.E. HansenPhysician Health and Safety
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13
■■■
Physician Health and Safety
in the Angiography Suite
MARGARET E. HANSEN
■ Infectious Risks
Non-bloodborne pathogens
Although blood-borne pathogens may stimulate more concern among health care workers (HCWs) and pa­tients, certain non-bloodborne agents are also important, particularly in hospital settings. Many pathogens are transmitted by droplet infection or by direct contact. Influenza and childhood diseases such as measles and rubella can be transmitted between HCWs and patients. Patients can be infected by asymptomatic HCWs har­boring these viruses, hence the recommendation that all HCWs be vaccinated against these three diseases. The elderly, the immunocompromised, and those with chronic diseases are at greatest risk for influenza. Immu­nity to rubella is important for women of childbearing age because severe fetal damage may result from congeni­tal infection.
The incidence of tuberculosis (TB) is increasing across the United States, especially in large cities. some is the emergence of multidrug resistant (MDR) strains, which can cause fulminant, rapidly fatal infection, particularly (but not only) in human immunodeficiency virus (HIV) -positive persons. HCWs in several cities have been infected on thejob, and several have died as aresult. Patients with known or suspected active TB infection should wear masks or particulate respirators, if possible, while undergoing procedures outside approved isolation rooms. Standard face masks do not filter particles in the droplet size range (1–5 lm) and are not adequate to pre­vent the spread of TB; for this reason, particulate respira­tors are preferred.
4
All radiology personnel involved in
1,2
Most worri-
procedures on patientswith active TB should wear respira­tors if possible.
Methicillin-resistant Staphylococcus aureus (MRSA), a se­rious problem in many hospitals, may be found in the nares or on the skin of HCWs and is spread primarily by the hands (5). Handwashing is criticalin preventing trans­mission of MRSA; gloves, gowns, and masks should be used when caring for patients with this infection.
5
Bloodborne pathogens
The most important agents in this category are HIV and the hepatitis viruses. Concern about nosocomial trans­mission of these agents has increased dramatically in the past few years.
Scope of the problem
Although a great deal of publicity and concern has cen­tered on HIV, hepatitis B and C should be regarded as equally serious because these viruses are both more preva­lent and more infectious than HIV. breaks of HCW to patient transmission of hepatitis B virus (HBV) have been reported, and the Centers for Disease Control and Prevention (CDC) estimates that 8,000 to 12,000 HCWs are infected with HBV on the job each year.
3
Of these, 10% will become chronic viral carriers; about 200 deaths of HCWs are attributed to HBV-related disease each year. have serologic evidence of HBV exposure (⬎50% for for­eign-born Asians), and 0.2 to 13% are chronic carriers. Among hospitalized patients, at least 1% are HBV carri­ers, most asymptomatic and unaware of their carrier status.
7
Between 3 and 14% of the general population
7
Hepatitis C virus (HCV) isalso prevalent in certain
6
More than 20 out-
137
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M. E. Hansen
groups: studies indicate exposure in 1 to 4% of HCWs, 12% of dialysis patients, and 50 to 80% of injecting drug users and hemophiliacs.
8,9
The prevalence of HIV infection in the United States is estimated to be about 1% in the general population. although it is higher in certain groups, such as emer-
11
gency department patients (6%)
and young urban
adults treated for penetrating trauma (19% in one
12
study). in acute care hospitals ranges from 0.2% to 14.2%.
The prevalence of HIV infection among patients
13
Means and risk of transmission
Transmission of HIV, HBV, and HCV occurs through blood contact and sexual contact. In the health care setting, this generally involves needlestick injuries, but contact with mucous membranes or nonintact skin also has resulted in HIV infection.
14
Transmission after con­tact with intact skin has not been reported. In addition to blood, other body fluids may be infectious. HIV has been detected in saliva, semen, vaginal secretions, breast milk, amniotic fluid, synovial fluid, cerebrospinal fluid, and serous exudates from infected persons.
7
HBV can be pre-
sent in most of these fluids, too, as well as in urine and
7
feces.
HCV has not been recovered from vaginal fluid, semen, or saliva of chronically infected persons even when viremia is present, but otherwise has a distribution similar to that of HBV.
7
HBV is a fairly hardy virus, able to survive on environ­mental surfaces for up to 7 days at room temperature, but it is killed by bleach and other high-level disinfectants. HIV is also readily inactivated by household bleach and other high-level disinfectants, but it is less robust and survives only briefly on surfaces at room temperature.
7
The risk of infection after a single parenteral exposure depends on the infectivity of the source, the amount of blood or other fluid transferred, and other factors. Infec­tivity depends on the viral titers of the source. For HBV, the most infectious of the three viruses, the type of viral particle present in the blood is also important; hepatitis B e antigen (HBeAg) is the most infectious. Infection risk after one parenteral contact with HBV ranges from 7 to
7
30%;
with HCV from 2 to 4%,7and with HIV is about
15,16
0.4%.
For a given procedure, the risk of infection depends on the likelihood of parenteral contact during the procedure and the source’s likelihood of infection in addition to the above factors.
The risk of HCW-to-patient transmission is unknown but probably is much lower than the risk in the opposite direction. For such transmission to occur, the HCW must be infected with a blood-borne agent and sustain an in­jury that causes bleeding (or have open, exudative skin lesions, in which case the HCW should avoid patient contact), and then his or her blood must come into parenteral contact with the patient. Perhaps the most common scenario in which this might occur in the angio-
graphy suite is if a needle is reused on the patient after being contaminated with the blood of an HCW after a needlestick injury. If such contact occurs and the HCW is HIV positive, the risk of infecting the patient probably
10
would be about 0.4% (the same as for infection of an HCW after a single needlestick exposure).
15,16
modeling done by the CDC to estimate the risk of an HIV positive surgeon infecting a patient during a procedure yielded a range of 1/42,000 to 1/420,000 procedures. Modeling specific to vascular and interventional radiol­ogy has produced similar results, estimating the risk of infecting a patient to be 0.03 per million procedures if the radiologist’s HIV status is unknown and 7.5 per mil­lion procedures if the physician is HIV positive. estimated risk of patient-to-physician transmission of HIV for a single procedure ranges from 0.03 to 7.5 per mil-
18
lion.
Blood contacts and injuries in vascular/interventional radiology
Needlestick injuries occur less often in interventional ra­diology than in surgery. A recent prospective study noted needlestick injuries in 0.6% of interventional radiologic
19
procedures,
1.7 to 15.4% for surgical procedures.
compared with previously reported rates of
20–24
A national sur­vey of inter ventional radiologists found an annual me­dian injury rateof 0.3, of 2 in a survey of surgeons. sharps, such as leaving exposed sharps in the folds of a
7
25
compared with an annual median
26
Improper handling of
drape or under a towel, or recapping needles was a com-
19,25
mon source of injury to radiologists.
Procedure dura­tion, operator experience level, and elective versus emer­gency procedure status had no effect on the risk of injury, but the risk for nonvascular interventional procedures was slightly higher than for other types of cases. ous or mucous membrane exposures, including splashes to the face, eyes, or other areas, occured in 3% of cases. More than 70% of these blood contacts could have been avoided by using appropriate protective gear, such as gowns and goggles. Longer procedure duration was strongly associated with higher risk of such exposures, although not with higher risk of injury.
Glove perforations are another potentially important means of blood contact. Overall, occult perforations oc­cur in 10% of gloves used for angiographic or inter­ventional procedures, but the relationship between the length of time gloves are worn and the perforation rate is strong, with 2 hours being the dividing point between
27
low and high risk.
For this reason, it is prudent to change gloves during lengthy procedures at or before 2 hours of wear. Most of the holes are probably attributable to mechanical stresses, such as forceful hand injection or catching glove material in a stopcock, rather than actual sharp injuries.
Computer
18
The
19
Cutane-
17
19
19
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■ Risk-reduction Strategies
Universal precautions
The use of universal precautions (UP) has been recom­mended by the CDC since 1987 (Table 13-1. tenet of UP is the assumption that blood and body fluids from all patients should be considered potentially infec­tious. Rather than targeting the use of blood and body fluid precautions to “high-risk” cases only, UP mandates their routine use. Adherence to CDC infection control recommendations, including use of UP, was voluntary until 1992, when federal law made it mandatory.
28
The basic
7
Safety devices and personal protective gear
Many devices have been produced in attempts to reduce the risk of injury and blood contacts during procedures. “Needleless” intravenous systems (Fig. 13-1), self-sheath­ing needles, and needle-capping devices are among those in current use; improved containers for the disposal of sharps are now standard in most health care settings as well.
Several products have been designed specifically for interventional radiology, such as sharps holders for pro­cedure trays, closed flush systems, closed-system drainage kits, and “bloodless” arterial puncture systems. of these products are slightly more expensive than stand­ard versions (some of the needles may be significantly more expensive) and do not interfere with procedure performance. Tactile feel during guidewire introduction may be altered with the bloodless puncture devices, how-
TABLE 13-1.
Adherence to universal precautions
Blood and body fluids from
infectious
Use of safety devices and personal protective gear
Needleless intravenous systems Self-sheathing needles and needle-capping devices Sharps holders Closed flush systems Fluid-impermeable gowns Face shields, masks and goggles Caps, shoe covers, gloves
Safe handling of sharp instruments
Do not recap by hand unless one-handed method is used Maintain awareness regarding location and status of sharps
during procedure Remove sharps from field immediately after use Dispose of sharps promptly in appropriate container
Vaccinations
Hepatitis B Influenza, rubella, measles Tetanus Future vaccines: hepatitis C, human immunodeficiency virus?
Strategies for risk reduction in interventional radiology
all
patients are potentially
29–33
Most
ever, which should be kept in mind when these devices are used.
34
Personal protective equipment has been available for a long time, but some improvements have been made re­cently. Fluid-impermeable gowns are now widely used, some of which offer added protection in areas where strike-through is most likely, such as the chest and sleeves. Clear plastic face shields and shield-mask combinations can be used by most people, including those who wear corrective eyeglasses. Most brands of goggles and shields provide side shielding as well, which is requiredby current safety standards.
Unfortunately, protective gear is not widely used in in­terventional radiology despite being affordable and read­ily available. Anecdotal evidence suggests that many radi­ologists often do not wear caps, masks, goggles, and shoe covers (or even gowns) while performing procedures. This evidence is supported by the survey of interventional radiologists mentioned earlier,
25
which found that only 20% of radiologists who do not wear corrective eyeglasses for procedures routinely used eye protection, and only 32% routinely wear a face mask or shield. Inconvenience and fogging of eyeglasses are commonly cited reasons for failure to use these items; given the many stylesof masks or shields now available, one should be workable for almost everyone, and persons who have such concerns should try different brands.
Safe sharp handling
Proper handling of sharp instruments includes not recap­ping them by hand and prompt disposal of used sharps in an appropriate container. Preferably, sharps should not be recapped at all, but if this must be done, a me­chanical device such as a sheath guard or a hemostat should be used. The one-handed method in which the cap is scooped up with the needle, fingers well away from its tip, is also acceptable but slightly more risky. Commu­nication between team members during procedures is perhaps the most important element of safe handling of sharps so that all persons involved in a case are aware of the location and status of all sharp instruments in use. It never should be assumed by one team member that an­other person has seen where a sharp has been placed; verbal communication is essential. Removing sharps from the field immediately after use is also important in avoid­ing inadvertent injury. Leaving exposed sharps in the folds of a drape is a common cause of injury.
25
Prompt disposal of used sharps in a puncture- and spill-proof container is the final element in safe handling.
Vaccinations
Vaccination against HBV is recommended for all HCWs at risk for occupational exposure to blood or other poten-
140 M. E. Hansen
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Figure 13-1. A: Saf-Site (Burron Medical Inc., Bethlehem, PA), a “needleless” intravenous access system features a one-way valve that is opened by inserting the syringe tip into the hub of the device; caps are also available. B: The InterLink device (Becton Dickinson, Franklin Lakes, NJ) is similar, with a hep-lock style hub that is penetrated by the special syringe tip.
BA
tially infectious materials and now must be offered free of charge to such employees.
7
Because it is produced by recombinant DNA technology, the current vaccine car­ries no risk of pathogen transmission.
35
Booster doses may be needed in some cases. Currently, no vaccines are available for HCV or HIV, although intensive research effort is under way.
Vaccination against rubella, tetanus, influenza, and measles is recommended for all HCWs. Rubella vaccine is contraindicated during pregnancy, which should be avoided for 3 months after vaccination. also is contraindicated during pregnancy.
36
Measles vaccine
37
Influenza vaccines are formulated each year against strains thought to be common in the coming flu season, and revaccina­tion is needed annually.
38
■ What to Do If Exposure Occurs
Blood testing
After a parenteralexposure to blood or body fluid, therisk of the source individual’s being infected with a blood­borne pathogen should be assessed and appropriate sero­logic testing performed as soon as possible (Table 13-2). Both the source and the exposed person should be tested for evidence of HIV, HBV, andHCV infection initially.
If the source is HIV positive, the exposed person should be retested for HIV 3 and 6 months after exposure if the initial test has a negative result. Safe sexual practices should be followed during this period, and sharing of toothbrushes, needles, or razors should be avoided. Dona­tion of blood, organs, and sperm should be avoided as well, and preventing pregnancy for 6 months is recom­mended.
39
Repeated serologic testing is recommended to be
done 6 and 9 months after exposure to HCV. If infection is diagnosed, liver-function testing should be done to determine whether any treatment or further follow-up is needed.
39
HIV and hepatitis prophylaxis
If the source is HIV positive, the exposed person should be counseled about antiviral prophylaxis using zidovu­dine (ZDV), an agent that is active against human retro­viruses such as HIV, possibly in combination with other antiretroviral drugs. ZDV prophylaxis is widely used, al-
TABLE 13-2.
Determine which pathogens might be involved by initial blood testing
Source: HIV, HBV, HCV if status unknown Exposed person: HIV, HBV, HCV if status unknown
HBV exposure of nonimmune person
Start HBV vaccine series within 7 days of exposure Give HBV immunoglobulin within 24 hr of exposure
Repeat blood testing of exposed person based on results of initial tests
HIV-positive source: test at 3 and 6 mo if initial test negative HCV-positive source: test at 6 and 9 mo if initial test negative HBV-positive source: test at 4 and 6 mo after immunoglobulin
39
given
Chemoprophylaxis against HIV
Recommendations vary based on the degree of risk from exposure For high-risk exposure, combination of three antiretroviral drugs
used For lower-risk cases, one or two drugs recommended Recommendations may change in the future
Counseling and follow-up
If exposed to HIV, practice safe sex, refrain from blood and organ
donation, and prevent pregnancy for 6 mo If HCV infection develops, check liver function tests as needed In all cases, counseling by an experienced professional is vital
,HIV, human immunodeficiency virus; HBV, hepatitis B virus, hepatitis C virus.
What to do if exposure occurs
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though side effects are common.
40–42
If prophylaxis is elected, it should be started as soon as possible after expo­sure, ideally within an hour, as HIV infection may be es­tablished within a few hours. Several dosage regimens have been used.
39,41–43
The most recent recommenda­tions issued by the U.S. Public Health Service in mid-1996 vary with the level of risk (based on the route of exposure and type of material involved, i.e., blood versus other fluids) and include the use of ZDV and one or more of the newer antiretroviral agents, such as indinavir or saqui­navir. Because these recommendations may change with experience, and as newer drugs become available, the best course is to report all injuries immediately and to seek appropriate counseling regarding current recom­mendations.
If the source has evidence of HBV infectivity (HBsAg or HBeAg in the blood) and the exposed person has not been vaccinated against HBV or had a previous infection, the HBV vaccine series should be started within 7 days of exposure.
39
Hepatitis B immunoglobulin also should be given within 24 hours of exposure, but the two injections must not be given in the same site because they might inactivate each other. Follow-up testing for development of infection or establishment of immunity should be done 4 to 6 months after immunoglobulin administra­tion. Exposed persons who follow the recommended pro­phylaxis regimen pose little risk to patients and other contacts, and patient-care activities need not be restricted during the interval between tests.
39
No effective prophylaxis against HCV infection is cur­rently available. Immunoglobulin has not been shown to prevent HCV infection, and its use for this purpose is not recommended. Interferon alfa, although used with some success in the treatment of chronic HCV infection, has no role in preventing infection.
39
Counseling is as important after exposure to a blood­borne pathogen as are the serologic testing and prophy­lactic measures described previously. Counseling should be done by a health care professional who is experienced in this area.
■ Infection Control Regulations
1992 OSHA Bloodborne pathogen standard
In 1992, the Bloodborne Pathogen Standard of the Occu­pational Safety and Health Administration (OSHA) be­came federal law. that affect all radiologists, interventional radiologists in particular (Table 13-3). The standard applies to all em­ployees with potential occupational exposure to blood or other infectious materials, except those in certain state, county, or city facilities. Volunteers and students are not covered unless they are also employees. Exposure need
7
This statute has several major provisions
TABLE 13 -3.
Employers must develop an exposure control plan Employers must provide personal protective equipment and
mandate its use
Employers must provide HBV vaccination and postexposure
evaluation and treatment for HIV and hepatitis; vaccination must
be free of charge All employees must have annual training in infection control Employers must keep records of training sessions Employers must keep medical records for at-risk employees,
including HBV vaccination, exposure, and treatment Employers must provide facilities for handwashing and sharps
disposal Use and storage of food, drink, and cosmetics prohibited in at-risk
areas Recapping of sharps by hand prohibited Sharps disposal containers must be leak- and puncture-proof Contaminated laundry must be placed in labeled or color-coded bags Specimens must be placed in labeled or color-coded bags
HBV, hepatitis B virus; HIV, human immunodeficiency virus; OSHA, Occupational Safety and Health Administration.
Infection control regulations: 1992 OSHA Bloodborne Pathogen Standard
not occur frequently for the standard to apply, and if any part of a person’s job poses an exposure risk, he or she is covered by allprovisions of the standard.
Employers must develop an exposure control plan that identifies employees at risk, details how the standard will be implemented, specifies how exposures will be dealt with, is reviewed and updated at least annually, and is accessible to employees and to OSHA.
They also must provide personal protective equipment, including gloves, gowns, masks, goggles, caps, shoe cov­ers, and other items as needed. The use of such equip­ment is mandatory whenever exposure to blood or body fluid may be “reasonably anticipated” (no specific proce­dures or situations are cited in the standard), and the equipment provided must be clean, readily available in appropriate sizes, in good repair, and free of charge to employees. Hypoallergenic gloves or glove liners must be provided if needed.
In addition, HBV vaccination and postexposure evalu­ation and treatment for HIV and HBV must be provided. Vaccination must be offered free of charge to all employ­ees who are at risk an average of one or more times per month; those declining must sign a waiver. Free booster doses also must be provided.
All employees at risk must be trained in infection con­trol, with sessions repeated at least once a year. Medical records for employees at risk must include documenta­tion of HBV vaccination, exposures, and postexposure treatment and must be kept for the duration of employ­ment plus 30 years.
Readily available handwashing facilities and containers for sharps disposal must be provided. Work-practice con­trols must be established, such as prohibiting the use or storage of food, drink, or cosmetics in at-risk areas; hand-
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washing immediately after removal of gloves or other protective gear; prohibiting recapping of sharps; and im­mediate washing of skin and flushing of mucous mem­branes after contact with potentially infectious material.
Containers for the disposal of sharps are required to be leakproof, spillproof, closable, and located as close as pos­sible to the point(s) of sharps use. Contaminated laundry must be placed in appropriately labeled or color-coded bags, as must specimens. Biohazard labels or red bags/ containers must be used for all potentially infectious ma­terials.
Recently, guidelines regarding bloodborne pathogens were developed and published by the Society of Cardio­vascular and Interventional Radiology.
44
These guide­lines incorporate many elements of the OSHA standard as well as some from other sources and are specific to interventional radiology practice.
Resources for education and training
Many resources are available for education and training in infection control and to assist physicians in complying with the OSHA standard. Many commercial products, such as videos, workbooks, and seminars, are available. Local infectious disease specialists or infection-control practitioners are a valuable resource; state or local medi­cal or radiologic societies also may be able to provide information on these topics.
REFERENCES
1. Goldsmith MF. Medical exorcism required as revitalized revenant of tuberculosis haunts and harries the land. JAMA 1992;268:174–175.
2. Menzies D, Fanning A, Yuan L, et al. Tuberculosis among health care workers. N Engl J Med 1995;332:92–98.
3. Centers for Disease Control. Nosocomial transmission of multi­drug resistant tuberculosis among HIV-infected persons—Florida and New York, 1988–1991. MMWR 1991;40:585–591.
4. Centers for Disease Control. Guidelines for preventing the trans­mission of tuberculosis in health-care settings, with special focus on HIV-related issues. MMWR 1990;39(RR-17):1–29.
5. Wenzel RP, Nettleman MD, Jones RN, et al. Methicillin-resistant Staphylococcus aureus: implications for the 1990s and effective con­trol measures. Am J Med 1991;91(Suppl 3B):221S–227S.
6. Lettau LA. The A, B, C, D, and E of viral hepatitis: spelling out the risks for healthcare workers. Infect Control Hosp Epidemiol 1992; 13:77–81.
7. OSHA. Occupational exposure to bloodborne pathogens: final rule (29 CFR 1910.1030). Federal Register 1991;56:64003–64182.
8. Polywka S, Laufs R. Hepatitis C virus antibodies among different groups at risk and patients with suspected non-A, non-B hepatitis. Infection 1991;19:81–84.
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