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194 J. A. Bello and B. Berkowitz
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A
FIGURE 18-8. A: Digital subtraction angiography of the aortic
arch (anteroposterior projection) of an early arterial phase demonstrates multiple smooth stenoses of the great vessels, including the origins of the left common carotid artery (
arrowhead
tion to stenosis more distally in the left subclavian artery
curved arrow
( artery ( arch injection, reconstitution of the right subclavian artery (
large arrowhead
rowhead
of the left common carotid artery in the lateral projection dem­onstrates stenoses of the proximal left internal and external
C
carotid arteries.
) and left subclavian artery (
). Note the occlusion of proximal innominate
large arrowhead
) is demonstrated. C: Digital subtraction angiography
). B: Later in the arterial phase of the
) and right common carotid artery (
straight arrow
)inaddi-
small ar-
B
small
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195
A B
FIGURE 18-9. A and B: Anteroposterior, sequential digital subtraction angiograms in the anteroposterior projection demonstrate
retrogade flow of contrast into the left vertebral artery (B) from the right vertebral artery, which fills antegrade from a right subclavian artery injection. Note reflux filling of the right common carotid artery. (Courtesy of Dr. Paul Sane.)
Paragangliomas
Paragangliomas, of which chemodectomas are a subset, are locally invasive, highly vascular tumors that arise from
7
paraganglion cells.
Typically, they are located at the bi­furcation of the carotid arter y, along the vagus nerve within the jugular vein or within the middle ear along Jacobson’s nerve, but they may occur in other locations (Fig. 18-11). Paragangliomas are more prevalent in women (3:1) and have a peak incidence in the fourth to fifth decade of life. These lesions usually are supplied by the branches of the ECA, but may recruit blood supply from other vessels. As a result of their hypervascularity and propensity to bleed profusely at surgery, preopera­tive angiography with embolization is often performed, especially for glomus jugulare tumors.
Juvenile angiofibroma
Juvenile angiofibroma is a highly vascular nasopharyn­geal neoplasm that affects adolescent males. Although the tumor is histologically benign, it may be extremely
8
aggressive and invade surrounding structures.
Patients with this tumor are at high risk for life-threatening hem­orrhage. Angiography is performed to discern the extent of the tumor and for preoperative embolization. During an episode of uncontrolled bleeding, embolization may be life saving. The blood supply of these tumors originates from the distal internal maxillary artery in most cases; as the tumor grows, any vessel in its vicinity may be parasitized, including branches of the internal carotid artery. Before embolization of these tumors, care­ful examination of the ICAs must be made to safeguard
196 J. A. Bello and B. Berkowitz
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A B
FIGURE18-10. Digital subtraction injection of the aortic arch
in the anteroposterior projection in early arterial (A) and midar­terial (B) phases demonstrates filling of the false and true lumen ( spontaneous left common carotid dissection. Axial contrast enhanced dynamic computed tomography (CT) scan through the neck demonstrates bilateral common carotid artery dissec­tions. (C). Note the differential filling of the false and true lumen ( differential opacification of the right and left vertebral arteries
C
as well (also apparent in the arch injection [A,B]).
curved arrow
curved arrow
) in a hypertensive patient status post
) of the left common carotid artery. There is
Carotid, Vertebral, and Spinal Arteriography 197
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against refluxing embolic material into the ICA circula­tion.
Meningioma
Most meningiomas occur in a supratentorial location; however, they may involve the skull base and spinal cord. Meningiomas are typically vascular, exhibiting a dense contrast stain that appears in the early phase of the injec­tion and lingers until late into the venous phase (Fig. 18-12). Preoperative embolization is performed if the blood supply to the lesion is judged to be potentially difficult to control surgically.
Arteriovenous malformations
Arteriovenous malformations (AVMs) constitute the bulk of nonneoplastic lesions for which angiography is routinely obtained. AVMs are congenital lesions that are thought to result from abnormal embr yological devel­opment of the vascular system. They are high-velocity arteriovenous shunts that consist of a tangle of abnormal
A
B
FIGURE 18-11. A: Right common carotid angiogram demon-
strates paraganglioma tumor vascularity ( branches of the enlarged occipital artery. B: Digital subtraction angiography of the right vertebral artery in the lateral projection demonstrates that the tumor also is supplied by the vertebral artery.
arrows
) supplied by
FIGURE 18-12. Digital subtraction angiography (lateral pro­jection) of selective left occipital artery injection ( shows extensive tumor blush supplied by the left occipital branches. Note the transtumoral filling of the anteriorly bowed ascending pharyngeal artery ( plied the meningioma.
curved arrow
straight arrow
), which also sup-
)
198 J. A. Bello and B. Berkowitz
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vessels with arterial feeders and enlarged draining veins. Although most of these lesions are intracranial, AVMs of the neck, scalp, and face do occur.
7
As with the other processes already mentioned, angiography of these lesions is undertaken to define the extent of the lesion and for preoperative embolization. In traumatic AVFs and pseudoaneurysms, embolization may be curative.
9
Hemangioma
Cavernous hemangiomas, or cavernous venous malfor­mations, are relatively common and may occur in the head and neck region. Composed of large, cavernous vascular spaces, these malformations may grow to a large size. These lesions generally are removed for cosmetic reasons, but they may become symptomatic as a result of thrombosis or mass effect on adjacent structures. Cavern­ous venous malformations are not associated with arte­riovenous shunting. Angiographic study usually demon­strates a normal arterial phase with puddling of contrast within enlarged venous spaces (Fig. 18-13). Arterial em­bolization is usually not indicated, unless as a preopera­tive measure.
A
Refractory epistaxis
Refractory epistaxis is an important indication for angio­graphy. In most episodes of epistaxis, the bleeding point occurs in the anterior portion of the nasal cavity and is easily controlled by packing or cauterization. Bleeds that originate in the posterior or superior nasal cavity are more difficult to manage and often require posterior packs or ligation of the internal maxillary arter y. Poste­rior packs have a significant failure rate and are associ­ated with complications such as pressure-induced necro­sis and life-treatening hypoxia.
10
Selective embolization and superselective embolization have emerged as alterna­tives to surgical management of uncontrolled epistaxis. The distal branches of the internal maxillary artery usu­ally supply the bleeding site, but branches of the facial artery, and less commonly the internl carotid artery, may be involved. As is the case with juvenile angiofibroma, the ICA as well as the ECA must be studied before emboliza­tion is done to define the source of the bleeding accu­rately and to prevent inadvertent embolization of the ICA circulation.
■ Vascular Anatomy of the Spinal Cord
B
FIGURE 18-13. Lateral projection of left external carotid arte-
rial injection in early arterial (A) and capillary (B) phases dem­onstrates contrast puddling characteristic of hemangioma (
open arrows
internal maxillary artery (
arrowhead
(
) supplied by the inferior alveolar branch of the
closed arrow
), which is best seen in the arterial phase.
). Note in A, facial artery
The vascular supply of the spinal cord is provided by the anterior spinal artery and paired posterior spinal arteries (Fig. 18-14A). These arteries arise from the vertebral ar­teries. The anterior spinal arter y originates as paired branches of the vertebral artery that then fuse. The ante­rior spinal artery runs within the anterior median fissure
and supplies the anterior two-thirds to four-fifths of the cord. The posterior spinal arteries course along the pos­terolateral surface of the spinal cord in the region of the dorsal root entry zone. The volume of blood provided by the vertebral arteries is not sufficient to supply the entire cord, and below the level of C4–C5, the spinal arteries
Carotid, Vertebral, and Spinal Arteriography 199
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A,B
rely on anastomoses from radiculomedullary arteries (Fig. 18-14B). The origins of the radiculomedullary arter­ies vary and may arise from the vertebral, ascending cer­vical, intercostal, and lumbar arteries (Fig. 18-15). The artery of Adamkiewicz, or arteria radicularis magna, is the largest of the radiculomedullary arteries and generally arises from a left-sided intercostal artery between the levels of T9–12. This artery has a characteristic hairpin curve when seen on anteroposterior angiography (Fig. 18-16). The artery of Adamkiewicz is the main source of blood for the lower cord, and cross-clamping of the aorta above the level of this arter y may result in catastrophic neurological deficit.
11
Venous drainage of the spinal cord is accomplished by intramedullary veins that empty into an extensive venous plexus within the meninges and finally into the external venous plexus or Batson’s plexus.
FIGURE 18-14. Spinal cord arterial supply. Lateral (A) and anterior (B) views.
■ Angiography of the Spine, Head,
and Neck
Indications for spinal angiography
Angiography is generally not an indicated examination in the evaluation of most disease processes of the spinal cord. Angiography of the spinal cord is performed most commonly for the delineation and treatment of spinal AVMs and for vascular primary and metastatic neoplasms of the bony canal. One of the crucial indications for spinal cord arteriography is to locate the artery of Adamkiewicz before treatment begins, in cases where interruption of the thoracic aortic blood flow may be necessary or where endovascular embolization is being contemplated. Given the reliance of the spinal cord on anastomatic arter­ies for its blood supply, meticulous technique must be
12
A B
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FIGURE 18-15. A: Preembolization digital subtraction anteroposterior (AP) projection of selective left T3 intercostal artery (
arrow
) demonstrates tumor vascularity. B: Postembolization digital subtraction AP projection of the left T3 intercostal artery.
A
FIGURE 18-16. A: Anteroposterior (AP) projection of selective left intercostal arterial injection demonstrates filling of the left T10
and T11 intercostal arteries from a common trunk ( (
arrow
). B: AP projection digital subtraction angiography of a selective right T9 intercostal artery injection illustrates extensive
paraspinal tumor neovascularity. This represents surgically proven nodal metastasis from renal cell carcinoma.
arrowhead
B
). In addition, filling of the artery of Adamkiewicz is critical to note
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used when performing spinal angiography to avoid em­bolization or thrombosis of these vessels. There are no absolute contraindications to spinal angiography.
Indications for head and neck angiography
With the advent of multiplanar imaging, the role of angiography in pathological processes of the neck has diminished, although there are multiple indications for which angiography is still performed. It is routinely per­formed in conjunction with cerebral arteriography. Trauma to the neck in which vascular injury is suspected or cannot be excluded is a common indication for angiography. As previously noted, the percent of positive findings in patients stable enough to undergo angiogra­phy is low, and controversy exists as to whether angio­graphy should be performed unless there is a strong suspicion of vascular injury.
13
Evaluation of extracranial carotid disease in both symptomatic and asymptomatic patients with duplex evidence of carotid stenosis is a common indication for angiography. Although recent large-scale studies in both symptomatic and asymptoma­tic patients have affirmed the efficacy of carotid endar­terectomy in the prevention of stroke,
3,4
the need for preoperative angiography versus duplex alone or duplex in conjunction with magnetic resonance angiography (MRA) has been questioned. The Asymptomatic Carotid Artery Stenosis (ACAS) study used both arteriography and ultrasound as separate admitting criteria and stated that the complication rate of carotid angiography signifi­cantly added to the morbidity of endarterectomy in the surgical cohort.
3
With this in mind, the indications for angiography of the neck, as in other parts of the body, must be weighed in consideration of the risk-benefit ra­tio. Angiography should be considered in cases of known trauma to vascular structures, assessment of vascular pa­thology and malformations, preoperative “road map­ping,” and in preparation for interventional endovascu­lar procedures such as embolization.
Contraindications for angiography of the spine, head, and neck
There is no absolute contraindication to angiography of the head and neck, although there are a few relative contraindications that are not specific to angiography of this region of the body, including bleeding diatheses, contrast allergy, and compromised renal function. Con­current migraine headache is thought to be a relative contraindication, because the increased potential for va­sospasm in these patients may lead to serious complica­tions, most of which pertain to the posterior circulation (i.e., cortical blindness), in relation to selective cerebral angiography.
1
which occurs more specifically
Angiography versus other modalities
Recently, other imaging modalities have evolved that are able to assess the vascular structures in the neck, includ­ing duplex Doppler ultrasound, MRA, and computed tomographic angiography (CTA). Ultrasound is the most frequently used modality in the assessment of carotid disease and has the advantages of being noninvasive, easily tolerated, and relatively inexpensive. Its disadvan­tages include being operator dependent and, to a certain extent, anatomy dependent in that some vascular struc­tures are inaccessible and that heavily calcified or tortu­ous vessels may render the study difficult to interpret. MRA is noninvasive and less affected by vessel tortuosity or position, and multiplanar/three-dimensional recon­struction can be obtained. MRA shares the disadvantage of being adversely affected by heavily calcified vessel (field inhomogeneity effects) and being relatively expen­sive and susceptible to motion artifact. In addition, it is more difficult to monitor the patient while he or she is in the magnet. advent of spiral CT and fast computer reconstruction. The advantages of CTA include the ability to view the images in any plane, its relatively low cost, and minimal invasiveness. The disadvantages include long post­processing times, the necessity for iodinated contrast, and the fact that heavily calcified vessels significantly add to the difficulty of postprocessing, thus affecting the ac­curacy of the study. modalities, angiography is most accurate in the assess­ment of stenotic lesions. In a recent study, and MRA have been shown to have 65% and 52% exact correlation with angiography, respectively, with both mo­dalities tending to exaggerate stenoses. CTA has been shown to compare favorably with ultrasound and MRA, but it is not as accurate as angiography. with the superiority of angiography in the assessment of stenotic lesions as well as its versatility, it will continue to be performed until other modalities are proven superior or the discrepancy rates of these other modalities become insignificant compared with the complication rate of angiography.
References
1. Osborne AO. Introduction to Cerebral Angiography. Philadelphia: Har- per & Row, 1980.
2. Kilgore BB, Fields WS. Arterial occlusive disease in adults. In: New­ton, TH, and Potts DG, eds. Radiology of the Skull and Brain, vol 4, 1974:2310–2343.
3. Endarterectomy for asymptomatic carotid artery stenosis. JAMA 1995;273:1421–1428.
4. North American Symptomatic Carotid Endarterectomy Trial col­laborators. N Engl J Med 1991;325:445–453.
5. Hall S, Barr W, Lie JT, et al. Takayasu arteritis: a study of 32 North American patients. Medicine 1985;64:89–99.
6. North CM, Ahmadi J, Segall HD, et al. Penetrating vascular injuries
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CTA has become readily available with the
15
In comparative studies between
13
ultrasound
15
In summary,
14
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of the face and neck: clinical and angiography correlation. AJR Am J Roentgenol 1986; 147:995–999.
7. Hurst RW. Inter ventional neuroradiology of the head and neck. Neuroradiol Imaging Clin North Am 1996;2:473–495.
8. Moulin G, Chagnoud C, et al. Juvenile nasopharyngeal angiofi­broma: comparison of blood loss during removal in embolized group versus nonembolized group. Cardiovasc Inter vent Radiol 1995;18:158–161.
9. Schwartz RB, Jones KM, Chernoff DM. Common carotid artery bifurcation: evaluation with spiral CT. Radiology 1992;185:513–519.
10. Elden L, Montenara W, Terbrugge K, et al. Angiographic emboliza­tion for the treatment of epistaxis: a review of 108 cases. Otolaryngol Head Neck Surg 1994;111:44–50.
11. Anson JA, Spetzler RF. Interventional radiology for spinal pathol­ogy. Clin Neurosurg 1992;39:388–417.
12. Savader SJ, Williams GM, Trerotola SO, et al. Preoperative spinal artery localization and its relationship to postoperative neurologi­cal complications. Radiology 1993;189:165–171.
13. Clark GC, Lim RC, Rosenberg JM. cervicothoracic vascular injuries. presentation, management, and outcome. Am Surg 1991;57:582–
587.
14. Riles TS, Eidelman EM, Litt AW, et al. Comparison of magnetic resonance angiography, conventional angiography, and duplex scanning. Stroke 1992;23:341–346.
15. Schenck EA, Bond MG, Aretz TH, et al. Multicenter validation study of real-time ultrasonography, arteriography, and pathology: pathologic evaluation of endarterectomy specimens. Stroke 1988; 19:288–296.
T. J.DiBartholomeo and J. CynamonVascular Anatomybelow the Diaphragm
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■■■
Vascular Anatomy below the Diaphragm
THOMAS J. DIBARTHOLOMEO AND JACOB CYNAMON
This chapter discusses the relevant anatomy of the ab­dominal aorta, from the diaphragm to the distal vessels in the foot. Mention is made ofimportant variant anatomy as well as collateral pathways. Detailed variant anatomy and collateral flow patterns are beyond the scope of this text.
■ Abdominal Aorta (Fig. 19-1A)
Inferior phrenic
The paired phrenic arteries usually arise from the aorta in close proximity to the aortic hiatus. The inferior phrenic supplies the abdominal surface of the diaphragm. In addi­tion to arisingdirectly from the aorta, it may arisefrom the celiac artery,its branchesor,rarely,from therenal arteries.
Celiac artery (Fig.19-1B)
The celiac artery arises ventrally from the abdominal aorta at the T12–L1 level. The typical branching pattern, seen in approximately 75% of individuals, is the left gas­tric, common hepatic and splenic arteries. In the remain­ing individuals, there not be less than a true trifurcation, with aberrant origin of the left gastric or the hepatic arteries. The left gastric artery gives off branches to the distal esophagus and gastric cardia. Branches also supply the lesser curvature of the stomach. The hepatic artery resides in the hepatoduodenal ligament and typically di­vides into right, middle, and left branches. In about 10% of the population, the right hepatic artery arises from the superior mesenteric artery and is termed a replaced right hepatic artery. Less common variants are origin of the left
gastric from the left hepatic artery, which is termed a replaced left gastric artery and left hepatic off the left gastric artery, a replaced left hepatic arter y. The cystic artery is most frequently a branch of the right hepatic artery. The right gastric artery is a small vessel that is seldom visualized without selective catheterization. The gastroduodenal ar­tery arises from the common hepatic artery in about three quarters of the population. It gives rise to anterior and posterior superior pancreaticoduodenal arteries and the right gastroepiploic artery. The splenic artery is typi­cally a tortuous vessel with a relatively long course to supply the spleen. The main branches are pancreatic, short gastric, and left gastroepiploic arteries. The splenic artery ultimately ramifies into segmental branches at or within the splenic parenchyma. Major pancreatic branches arise from the splenic artery.
Superior mesenteric artery (Fig.19-1C)
The superior mesenteric artery (SMA) supplies the midgut from the ligament of Treitz to the midtransverse colon. It typically arises about L-1. The origin is just caudal to the celiac artery origin. The first branch is the inferior pancreaticoduodenal artery, which divides and a branch anastomosis with the similarly named superior counter­part to form the pancreaticoduodenal arcades. Vessels found on the left side of the SMA are usually jejunal and ileal branches. The branches terminate as straight vessels, vasa recta, close to the serosa of the bowel. These vessels are located on the mesenteric side of the bowel.
Themiddlecolicarteryisamoderate-sizedvesselthat arises from the anterior surface, which divides into right and left branches. Its supply is to the transverse colon. There is
203