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194 J. A. Bello and B. Berkowitz
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A
FIGURE 18-8. A: Digital subtraction angiography of the aortic
arch (anteroposterior projection) of an early arterial phase
demonstrates multiple smooth stenoses of the great vessels,
including the origins of the left common carotid artery (
arrowhead
tion to stenosis more distally in the left subclavian artery
curved arrow
(
artery (
arch injection, reconstitution of the right subclavian artery
(
large arrowhead
rowhead
of the left common carotid artery in the lateral projection demonstrates stenoses of the proximal left internal and external
C
carotid arteries.
) and left subclavian artery (
). Note the occlusion of proximal innominate
large arrowhead
) is demonstrated. C: Digital subtraction angiography
). B: Later in the arterial phase of the
) and right common carotid artery (
straight arrow
)inaddi-
small ar-
B
small

Carotid, Vertebral, and Spinal Arteriography
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195
A B
FIGURE 18-9. A and B: Anteroposterior, sequential digital subtraction angiograms in the anteroposterior projection demonstrate
retrogade flow of contrast into the left vertebral artery (B) from the right vertebral artery, which fills antegrade from a right
subclavian artery injection. Note reflux filling of the right common carotid artery. (Courtesy of Dr. Paul Sane.)
Paragangliomas
Paragangliomas, of which chemodectomas are a subset,
are locally invasive, highly vascular tumors that arise from
7
paraganglion cells.
Typically, they are located at the bifurcation of the carotid arter y, along the vagus nerve
within the jugular vein or within the middle ear along
Jacobson’s nerve, but they may occur in other locations
(Fig. 18-11). Paragangliomas are more prevalent in
women (3:1) and have a peak incidence in the fourth to
fifth decade of life. These lesions usually are supplied by
the branches of the ECA, but may recruit blood supply
from other vessels. As a result of their hypervascularity
and propensity to bleed profusely at surgery, preoperative angiography with embolization is often performed,
especially for glomus jugulare tumors.
Juvenile angiofibroma
Juvenile angiofibroma is a highly vascular nasopharyngeal neoplasm that affects adolescent males. Although
the tumor is histologically benign, it may be extremely
8
aggressive and invade surrounding structures.
Patients
with this tumor are at high risk for life-threatening hemorrhage. Angiography is performed to discern the extent
of the tumor and for preoperative embolization. During
an episode of uncontrolled bleeding, embolization may
be life saving. The blood supply of these tumors
originates from the distal internal maxillary artery in
most cases; as the tumor grows, any vessel in its vicinity
may be parasitized, including branches of the internal
carotid artery. Before embolization of these tumors, careful examination of the ICAs must be made to safeguard

196 J. A. Bello and B. Berkowitz
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A B
FIGURE18-10. Digital subtraction injection of the aortic arch
in the anteroposterior projection in early arterial (A) and midarterial (B) phases demonstrates filling of the false and true
lumen (
spontaneous left common carotid dissection. Axial contrast
enhanced dynamic computed tomography (CT) scan through
the neck demonstrates bilateral common carotid artery dissections. (C). Note the differential filling of the false and true lumen
(
differential opacification of the right and left vertebral arteries
C
as well (also apparent in the arch injection [A,B]).
curved arrow
curved arrow
) in a hypertensive patient status post
) of the left common carotid artery. There is

Carotid, Vertebral, and Spinal Arteriography 197
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against refluxing embolic material into the ICA circulation.
Meningioma
Most meningiomas occur in a supratentorial location;
however, they may involve the skull base and spinal cord.
Meningiomas are typically vascular, exhibiting a dense
contrast stain that appears in the early phase of the injection and lingers until late into the venous phase (Fig.
18-12). Preoperative embolization is performed if the
blood supply to the lesion is judged to be potentially
difficult to control surgically.
Arteriovenous malformations
Arteriovenous malformations (AVMs) constitute the
bulk of nonneoplastic lesions for which angiography is
routinely obtained. AVMs are congenital lesions that are
thought to result from abnormal embr yological development of the vascular system. They are high-velocity
arteriovenous shunts that consist of a tangle of abnormal
A
B
FIGURE 18-11. A: Right common carotid angiogram demon-
strates paraganglioma tumor vascularity (
branches of the enlarged occipital artery. B: Digital subtraction
angiography of the right vertebral artery in the lateral projection
demonstrates that the tumor also is supplied by the vertebral
artery.
arrows
) supplied by
FIGURE 18-12. Digital subtraction angiography (lateral projection) of selective left occipital artery injection (
shows extensive tumor blush supplied by the left occipital
branches. Note the transtumoral filling of the anteriorly bowed
ascending pharyngeal artery (
plied the meningioma.
curved arrow
straight arrow
), which also sup-
)

198 J. A. Bello and B. Berkowitz
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vessels with arterial feeders and enlarged draining veins.
Although most of these lesions are intracranial, AVMs of
the neck, scalp, and face do occur.
7
As with the other
processes already mentioned, angiography of these
lesions is undertaken to define the extent of the lesion
and for preoperative embolization. In traumatic AVFs
and pseudoaneurysms, embolization may be curative.
9
Hemangioma
Cavernous hemangiomas, or cavernous venous malformations, are relatively common and may occur in the
head and neck region. Composed of large, cavernous
vascular spaces, these malformations may grow to a large
size. These lesions generally are removed for cosmetic
reasons, but they may become symptomatic as a result of
thrombosis or mass effect on adjacent structures. Cavernous venous malformations are not associated with arteriovenous shunting. Angiographic study usually demonstrates a normal arterial phase with puddling of contrast
within enlarged venous spaces (Fig. 18-13). Arterial embolization is usually not indicated, unless as a preoperative measure.
A
Refractory epistaxis
Refractory epistaxis is an important indication for angiography. In most episodes of epistaxis, the bleeding point
occurs in the anterior portion of the nasal cavity and is
easily controlled by packing or cauterization. Bleeds that
originate in the posterior or superior nasal cavity are
more difficult to manage and often require posterior
packs or ligation of the internal maxillary arter y. Posterior packs have a significant failure rate and are associated with complications such as pressure-induced necrosis and life-treatening hypoxia.
10
Selective embolization
and superselective embolization have emerged as alternatives to surgical management of uncontrolled epistaxis.
The distal branches of the internal maxillary artery usually supply the bleeding site, but branches of the facial
artery, and less commonly the internl carotid artery, may
be involved. As is the case with juvenile angiofibroma, the
ICA as well as the ECA must be studied before embolization is done to define the source of the bleeding accurately and to prevent inadvertent embolization of the ICA
circulation.
■ Vascular Anatomy of the Spinal Cord
B
FIGURE 18-13. Lateral projection of left external carotid arte-
rial injection in early arterial (A) and capillary (B) phases demonstrates contrast puddling characteristic of hemangioma
(
open arrows
internal maxillary artery (
arrowhead
(
) supplied by the inferior alveolar branch of the
closed arrow
), which is best seen in the arterial phase.
). Note in A, facial artery
The vascular supply of the spinal cord is provided by the
anterior spinal artery and paired posterior spinal arteries
(Fig. 18-14A). These arteries arise from the vertebral arteries. The anterior spinal arter y originates as paired
branches of the vertebral artery that then fuse. The anterior spinal artery runs within the anterior median fissure
and supplies the anterior two-thirds to four-fifths of the
cord. The posterior spinal arteries course along the posterolateral surface of the spinal cord in the region of the
dorsal root entry zone. The volume of blood provided by
the vertebral arteries is not sufficient to supply the entire
cord, and below the level of C4–C5, the spinal arteries

Carotid, Vertebral, and Spinal Arteriography 199
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A,B
rely on anastomoses from radiculomedullary arteries
(Fig. 18-14B). The origins of the radiculomedullary arteries vary and may arise from the vertebral, ascending cervical, intercostal, and lumbar arteries (Fig. 18-15). The
artery of Adamkiewicz, or arteria radicularis magna, is the
largest of the radiculomedullary arteries and generally
arises from a left-sided intercostal artery between the
levels of T9–12. This artery has a characteristic hairpin
curve when seen on anteroposterior angiography (Fig.
18-16). The artery of Adamkiewicz is the main source of
blood for the lower cord, and cross-clamping of the aorta
above the level of this arter y may result in catastrophic
neurological deficit.
11
Venous drainage of the spinal cord is accomplished by
intramedullary veins that empty into an extensive venous
plexus within the meninges and finally into the external
venous plexus or Batson’s plexus.
FIGURE 18-14. Spinal cord arterial supply.
Lateral (A) and anterior (B) views.
■ Angiography of the Spine, Head,
and Neck
Indications for spinal angiography
Angiography is generally not an indicated examination in
the evaluation of most disease processes of the spinal
cord. Angiography of the spinal cord is performed most
commonly for the delineation and treatment of spinal
AVMs and for vascular primary and metastatic neoplasms
of the bony canal. One of the crucial indications for spinal
cord arteriography is to locate the artery of Adamkiewicz
before treatment begins, in cases where interruption of
the thoracic aortic blood flow may be necessary or where
endovascular embolization is being contemplated.
Given the reliance of the spinal cord on anastomatic arteries for its blood supply, meticulous technique must be
12

A B
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FIGURE 18-15. A: Preembolization digital subtraction anteroposterior (AP) projection of selective left T3 intercostal artery
(
arrow
) demonstrates tumor vascularity. B: Postembolization digital subtraction AP projection of the left T3 intercostal artery.
A
FIGURE 18-16. A: Anteroposterior (AP) projection of selective left intercostal arterial injection demonstrates filling of the left T10
and T11 intercostal arteries from a common trunk (
(
arrow
). B: AP projection digital subtraction angiography of a selective right T9 intercostal artery injection illustrates extensive
paraspinal tumor neovascularity. This represents surgically proven nodal metastasis from renal cell carcinoma.
arrowhead
B
). In addition, filling of the artery of Adamkiewicz is critical to note

Carotid, Vertebral, and Spinal Arteriography
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201
used when performing spinal angiography to avoid embolization or thrombosis of these vessels. There are no
absolute contraindications to spinal angiography.
Indications for head and neck angiography
With the advent of multiplanar imaging, the role of
angiography in pathological processes of the neck has
diminished, although there are multiple indications for
which angiography is still performed. It is routinely performed in conjunction with cerebral arteriography.
Trauma to the neck in which vascular injury is suspected
or cannot be excluded is a common indication for
angiography. As previously noted, the percent of positive
findings in patients stable enough to undergo angiography is low, and controversy exists as to whether angiography should be performed unless there is a strong
suspicion of vascular injury.
13
Evaluation of extracranial
carotid disease in both symptomatic and asymptomatic
patients with duplex evidence of carotid stenosis is a
common indication for angiography. Although recent
large-scale studies in both symptomatic and asymptomatic patients have affirmed the efficacy of carotid endarterectomy in the prevention of stroke,
3,4
the need for
preoperative angiography versus duplex alone or duplex
in conjunction with magnetic resonance angiography
(MRA) has been questioned. The Asymptomatic Carotid
Artery Stenosis (ACAS) study used both arteriography
and ultrasound as separate admitting criteria and stated
that the complication rate of carotid angiography significantly added to the morbidity of endarterectomy in the
surgical cohort.
3
With this in mind, the indications for
angiography of the neck, as in other parts of the body,
must be weighed in consideration of the risk-benefit ratio. Angiography should be considered in cases of known
trauma to vascular structures, assessment of vascular pathology and malformations, preoperative “road mapping,” and in preparation for interventional endovascular procedures such as embolization.
Contraindications for angiography of the
spine, head, and neck
There is no absolute contraindication to angiography of
the head and neck, although there are a few relative
contraindications that are not specific to angiography of
this region of the body, including bleeding diatheses,
contrast allergy, and compromised renal function. Concurrent migraine headache is thought to be a relative
contraindication, because the increased potential for vasospasm in these patients may lead to serious complications, most of which pertain to the posterior circulation
(i.e., cortical blindness),
in relation to selective cerebral angiography.
1
which occurs more specifically
Angiography versus other modalities
Recently, other imaging modalities have evolved that are
able to assess the vascular structures in the neck, including duplex Doppler ultrasound, MRA, and computed
tomographic angiography (CTA). Ultrasound is the most
frequently used modality in the assessment of carotid
disease and has the advantages of being noninvasive,
easily tolerated, and relatively inexpensive. Its disadvantages include being operator dependent and, to a certain
extent, anatomy dependent in that some vascular structures are inaccessible and that heavily calcified or tortuous vessels may render the study difficult to interpret.
MRA is noninvasive and less affected by vessel tortuosity
or position, and multiplanar/three-dimensional reconstruction can be obtained. MRA shares the disadvantage
of being adversely affected by heavily calcified vessel
(field inhomogeneity effects) and being relatively expensive and susceptible to motion artifact. In addition, it is
more difficult to monitor the patient while he or she is in
the magnet.
advent of spiral CT and fast computer reconstruction.
The advantages of CTA include the ability to view the
images in any plane, its relatively low cost, and minimal
invasiveness. The disadvantages include long postprocessing times, the necessity for iodinated contrast,
and the fact that heavily calcified vessels significantly add
to the difficulty of postprocessing, thus affecting the accuracy of the study.
modalities, angiography is most accurate in the assessment of stenotic lesions. In a recent study,
and MRA have been shown to have 65% and 52% exact
correlation with angiography, respectively, with both modalities tending to exaggerate stenoses. CTA has been
shown to compare favorably with ultrasound and MRA,
but it is not as accurate as angiography.
with the superiority of angiography in the assessment of
stenotic lesions as well as its versatility, it will continue to
be performed until other modalities are proven superior
or the discrepancy rates of these other modalities become
insignificant compared with the complication rate of
angiography.
References
1. Osborne AO. Introduction to Cerebral Angiography. Philadelphia: Har-
per & Row, 1980.
2. Kilgore BB, Fields WS. Arterial occlusive disease in adults. In: Newton, TH, and Potts DG, eds. Radiology of the Skull and Brain, vol 4,
1974:2310–2343.
3. Endarterectomy for asymptomatic carotid artery stenosis. JAMA
1995;273:1421–1428.
4. North American Symptomatic Carotid Endarterectomy Trial collaborators. N Engl J Med 1991;325:445–453.
5. Hall S, Barr W, Lie JT, et al. Takayasu arteritis: a study of 32 North
American patients. Medicine 1985;64:89–99.
6. North CM, Ahmadi J, Segall HD, et al. Penetrating vascular injuries
14
CTA has become readily available with the
15
In comparative studies between
13
ultrasound
15
In summary,
14

202 J. A. Bello and B. Berkowitz
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of the face and neck: clinical and angiography correlation. AJR Am
J Roentgenol 1986; 147:995–999.
7. Hurst RW. Inter ventional neuroradiology of the head and neck.
Neuroradiol Imaging Clin North Am 1996;2:473–495.
8. Moulin G, Chagnoud C, et al. Juvenile nasopharyngeal angiofibroma: comparison of blood loss during removal in embolized
group versus nonembolized group. Cardiovasc Inter vent Radiol
1995;18:158–161.
9. Schwartz RB, Jones KM, Chernoff DM. Common carotid artery
bifurcation: evaluation with spiral CT. Radiology 1992;185:513–519.
10. Elden L, Montenara W, Terbrugge K, et al. Angiographic embolization for the treatment of epistaxis: a review of 108 cases. Otolaryngol
Head Neck Surg 1994;111:44–50.
11. Anson JA, Spetzler RF. Interventional radiology for spinal pathology. Clin Neurosurg 1992;39:388–417.
12. Savader SJ, Williams GM, Trerotola SO, et al. Preoperative spinal
artery localization and its relationship to postoperative neurological complications. Radiology 1993;189:165–171.
13. Clark GC, Lim RC, Rosenberg JM. cervicothoracic vascular injuries.
presentation, management, and outcome. Am Surg 1991;57:582–
587.
14. Riles TS, Eidelman EM, Litt AW, et al. Comparison of magnetic
resonance angiography, conventional angiography, and duplex
scanning. Stroke 1992;23:341–346.
15. Schenck EA, Bond MG, Aretz TH, et al. Multicenter validation
study of real-time ultrasonography, arteriography, and pathology:
pathologic evaluation of endarterectomy specimens. Stroke 1988;
19:288–296.

T. J.DiBartholomeo and J. CynamonVascular Anatomybelow the Diaphragm
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■■■
Vascular Anatomy below the Diaphragm
THOMAS J. DIBARTHOLOMEO AND JACOB CYNAMON
This chapter discusses the relevant anatomy of the abdominal aorta, from the diaphragm to the distal vessels in
the foot. Mention is made ofimportant variant anatomy as
well as collateral pathways. Detailed variant anatomy and
collateral flow patterns are beyond the scope of this text.
■ Abdominal Aorta (Fig. 19-1A)
Inferior phrenic
The paired phrenic arteries usually arise from the aorta in
close proximity to the aortic hiatus. The inferior phrenic
supplies the abdominal surface of the diaphragm. In addition to arisingdirectly from the aorta, it may arisefrom the
celiac artery,its branchesor,rarely,from therenal arteries.
Celiac artery (Fig.19-1B)
The celiac artery arises ventrally from the abdominal
aorta at the T12–L1 level. The typical branching pattern,
seen in approximately 75% of individuals, is the left gastric, common hepatic and splenic arteries. In the remaining individuals, there not be less than a true trifurcation,
with aberrant origin of the left gastric or the hepatic
arteries. The left gastric artery gives off branches to the
distal esophagus and gastric cardia. Branches also supply
the lesser curvature of the stomach. The hepatic artery
resides in the hepatoduodenal ligament and typically divides into right, middle, and left branches. In about 10%
of the population, the right hepatic artery arises from the
superior mesenteric artery and is termed a replaced right
hepatic artery. Less common variants are origin of the left
gastric from the left hepatic artery, which is termed a
replaced left gastric artery and left hepatic off the left gastric
artery, a replaced left hepatic arter y. The cystic artery is most
frequently a branch of the right hepatic artery. The right
gastric artery is a small vessel that is seldom visualized
without selective catheterization. The gastroduodenal artery arises from the common hepatic artery in about
three quarters of the population. It gives rise to anterior
and posterior superior pancreaticoduodenal arteries and
the right gastroepiploic artery. The splenic artery is typically a tortuous vessel with a relatively long course to
supply the spleen. The main branches are pancreatic,
short gastric, and left gastroepiploic arteries. The splenic
artery ultimately ramifies into segmental branches at or
within the splenic parenchyma. Major pancreatic
branches arise from the splenic artery.
Superior mesenteric artery (Fig.19-1C)
The superior mesenteric artery (SMA) supplies the
midgut from the ligament of Treitz to the midtransverse
colon. It typically arises about L-1. The origin is just caudal
to the celiac artery origin. The first branch is the inferior
pancreaticoduodenal artery, which divides and a branch
anastomosis with the similarly named superior counterpart to form the pancreaticoduodenal arcades. Vessels
found on the left side of the SMA are usually jejunal and
ileal branches. The branches terminate as straight vessels,
vasa recta, close to the serosa of the bowel. These vessels
are located on the mesenteric side of the bowel.
Themiddlecolicarteryisamoderate-sizedvesselthat
arises from the anterior surface, which divides into right and
left branches. Its supply is to the transverse colon. There is
203
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