Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:

Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3715_Библиотеки_им_академика_М_И_Перельмана

.pdf
Скачиваний:
0
Добавлен:
31.08.2026
Размер:
31 Мб
Скачать
106
https://t.me/medicina_free
8 Imaging Studies andHaemodynamics inChronic Constrictive Pericarditis
In this study, extensive pericardial calcication were present in 5 (41.7%) patients, spreading over the anterior and inferior surfaces of ventricles. Despite extensive calcication, total pericardiectomy could be achieved in all patients of the study group. However these patients required higher inotropic support in the imme­diate postoperative period to tide over low cardiac output syndrome. This may be explained by underlying myocardial damage or atrophy, secondary to long standing encasement and penetration of the myocardium by calcium spurs, and persistent inammation. In addition, other investigators have suggested possibility of residual constriction, brous invasion of the myocardium and myocardial altercation leading to abnormal ventricular compliance.
The utility of speckle tracking echocardiography and tissue Doppler imaging in identifying residual constrictive pericarditis needs investigation on larger popula­tion and should be correlated with clinical outcomes [204]. In chronic constrictive pericarditis, the epicardial dysfunction leads to depressed global circumferential strain and left ventricular torsion (LVT), whereas global longitudinal strain and global radial strain are preserved (Figs.8.10, 8.11, 8.12, and 8.13).
Studies assessing the extent of myocardial damage with two-dimensional speckle tracking echocardiography in constrictive pericarditis are limited. In a study by Sengupta and associates, longitudinal, radial, and circumferential mechanics of the left ventricle were quantied by two-dimensional speckle tracking echocardiogra­phy on 26 patients with constrictive pericarditis and 19 patients with restrictive
Fig. 8.10 Two-dimensional speckle echocardiography showing global longitudinal strain (GLS pattern)– Preoperative
8.2 Echocardiography
https://t.me/medicina_free
Fig. 8.11 Two-dimensional speckle echocardiography showing global circumferential strain (GCS pattern)– Postoperative
107
Fig. 8.12 Two-dimensional speckle echocardiography showing global longitudinal strain (GLS pattern)– Postoperative
108
https://t.me/medicina_free
Fig. 8.13 Two-Dimensional speckle echocardiography showing global radial strain (GRS pattern)– Postoperative
8 Imaging Studies andHaemodynamics inChronic Constrictive Pericarditis
cardiomyopathy. Compared to controls, individuals with constrictive pericarditis had impaired left ventricle circumferential strain (ε) (base; 16± 6 vs −9± 6%; p<0.01) [194196, 202]. Amaki and associates validated the usefulness of two­dimensional speckle tracking echocardiography and cardiac magnetic resonance imaging on 30 patients with restrictive cardiomyopathy and 28 patients with con­strictive pericarditis [3].
8.3 Computed Tomography
In addition to cardiac structures, computed tomography and magnetic resonance imaging allows examination of the entire mediastinum and lungs. Computed tomog­raphy and magnetic resonance images provide excellent anatomic delineation, and are superior to echocardiography in evaluation of pericardial calcication, localized pericardial effusion, pericardial mass, and asymmetric pericardial thickening [8,
1825, 161, 164, 165, 167, 180, 234, 235].
Both computed tomography and magnetic resonance imaging are not operator dependent like echocardiography. Multidetector computed tomography enables motion-free pericardial imaging as well as multiplanar visualization of any pericar­dial disease. Computed tomographic attenuation measurements may provide tissue
8.3 Computed Tomography
https://t.me/medicina_free
characterization of some pericardial masses. Cardiac computed tomography has good spatial and temporal resolution, a wide eld of view, and multiplanar recon­struction abilities.
The limitations of computed tomography include the use of intravenously admin­istered iodinated contrast agents, ionizing radiations, and cardiac motion artifacts in non-ECG gated computed tomographic scans.
Although expert consensus guidelines on the diagnosis and management of peri­cardial diseases have been published, the role of multimodality imaging has not been clearly dened [118]. Clinically, routine application of these guidelines can be difcult because (a) exposure to iodinated contrast agent or ionizing radiation, (b) non-gated computed tomography possibly limiting the evaluation of the pericar­dium because of motion artifacts, (c) questionable cost effectiveness, and d) imag­ing that can be challenging in patients with arrhythmia or poor breath holders and in patients with unstable hemodynamics.
109
8.3.1 Pericardial Structural Evaluation
The normal pericardium on computed tomography ranges between 0.7 mm and 3mm; the ability to measure accurately is dependent on reconstructed slide thick­ness. Computed tomography is highly accurate in estimating the thickness of the pericardium and dening the distribution of thickening [54, 72, 73, 8592, 188].
The normal pericardium is identied as a curvilinear line of soft tissue density, whereas in chronic constrictive pericarditis the parietal pericardium may be 4–30mm thick. Although cardiac computed tomography is not a rst-line investiga­tion in patients with suspected constrictive pericarditis, it is useful in conrmation of diagnosis and preoperative planning for pericardiectomy including redo cases [85]. Pericardial thickness of 4 mm or more indicates abnormal thickening and, when accompanied by clinical ndings of congestive cardiac failure, is highly sug­gestive of chronic constrictive pericarditis [234, 235]. The distribution of pericardial thickening may be asymmetric located over the right heart or over the atrioventricu­lar groove [19, 2224].
Multidetector computed tomography offers additional information including location of cardiac and vascular structures relative to midline retro-sternum as well as associated aortic atherosclerosis, if any. In addition to features of pericardial disease, computerized tomographic scans of the chest may show typical mediastinal lymphadenopathy (i.e. enlargement >10mm with matting and hypodense centres) in almost 100% of cases in the acute phase that resolve on treatment [29]. In patients with abnormal symptoms, there may be ndings suggestive of diagnosis of constric­tive pericarditis with an abdominal computed tomography [8083].
However, there exists a cohort of patients with constrictive physiology and nor­mally appearing pericardium on imaging studies [214]. Despite normal thickness, these patients exhibit histologic evidence of inammation and calcication; there
110
https://t.me/medicina_free
8 Imaging Studies andHaemodynamics inChronic Constrictive Pericarditis
are distorted ventricular contours on magnetic resonance imaging. This subset of patients constituted 18% of patients with chronic constrictive pericarditis in the Mayo Clinic Series [214].
The incidence of pericardial calcication in tubercular chronic constrictive peri­carditis in the published literature ranges from 5% to 76% [1825, 30, 31, 58, 59,
62, 91, 114, 163165]. Several investigators have demonstrated that pericardial cal-
cication is predominantly located over the right atrium, right ventricle, diaphrag­matic surface and atrioventricular grooves [1825, 30, 31, 58, 59, 62, 91, 114,
163165]. Fluid displaced by the vigorous contraction of the left ventricle during
resorption of the primary pericardial effusion preferentially gravitates toward the right side of the heart. The inspissated uid over the right side forms the base for dystrophic calcication including bone formation in some cases. The apex and ante­rior wall of the left ventricle is often spared [163, 186]. Failure to visualize the posterolateral wall of the left ventricle on dynamic computed tomography suggests myocardial brosis or atrophy and is associated with poor surgical outcome [163, 186].
Since pericardial constriction can occur in patients with histologically normal pericardial thickness, other ancillary ndings need documentation, including biatrial enlargement, dilatation of the inferior caval vein, pleural effusions, and distorted ventricular contours (Figs.8.14, 8.15, 8.16, 8.17, 8.18, 8.19, 8.20, 8.21, 8.22, 8.23,
8.24, 8.25, 8.26, 8.27, 8.28).
a
b c
Fig. 8.14 Short axis non-contrast CT images (a and b) show presence of near circumferential pericardial calcication (arrowheads). Volume rendered image (c) of CT angiography depicts extensive pericardial calcication extending from the atrioventricular groove over the ventricular surfaces. (LA- Left atrium, LV-Left ventricle, MPA-Main pulmonary artery, RV-Right ventricle)
b
8.3 Computed Tomography
https://t.me/medicina_free
111
a
Fig. 8.15 Four chamber image (a) and volume rendered image (b) of CT angiography shows pericardial calcication (arrowhead) with a thick calcic spur inltrating into the left ventricular myocardium (large black arrow). (LA- Left atrium, LV-Left ventricle, MPA-Main pulmonary artery, RA-Right atrium, RV-Right ventricle)
b
a
c
Fig. 8.16 Sagittal (a) and axial (b) images show presence of thick sheet-like pericardial calcica­tion (arrowhead) along the diaphragmatic surface of the heart. Volume rendered image (c) viewed from below shows the sheet-like pericardial calcication (asterisk) along the diaphragmatic sur­face of the heart. (DTA-Descending thoracic aorta, IVC-Inferior caval vein, LA- Left atrium, LV-Left ventricle, RA-Right atrium, RV-Right ventricle)
112
bd
https://t.me/medicina_free
8 Imaging Studies andHaemodynamics inChronic Constrictive Pericarditis
a
Fig. 8.17 Axial (a) and four-chamber image (b) shows patchy pericardial calcication (arrow­head) anterior to right ventricular outow tract and in the region of atrioventricular groove. Volume rendered images (c and d) show the patchy pericardial calcication (asterisk). (LA- Left atrium, LV-Left ventricle, RA-Right atrium, RV-Right ventricle)
c
8.3.2 Cardiac Magnetic Resonance Imaging inChronic
Constrictive Pericarditis
Cardiac magnetic resonance is a second-line imaging modality for both structural and haemodynamic evaluation in chronic constrictive pericarditis [46, 85, 97, 100,
167, 215, 218, 235]. Cardiac magnetic resonance has high spatiotemporal resolu-
tion; it enables excellent anatomic delineation of the pericardium and also effec­tively characterizes features of constrictive,physiology [5, 6, 45, 46, 56, 6975, 98,
99, 155, 156, 164, 165, 167, 215, 216, 218, 234, 235] Its unrestricted imaging eld
8.3 Computed Tomography
https://t.me/medicina_free
113
a
Fig. 8.18 Short axis image (a) and volume rendered image (b) viewed from below shows a peri­cardial collection (asterisk) with patchy calcication of both the parietal (white arrowheads) and visceral pericardium (black arrowheads). (LA- Left atrium, LV-Left ventricle, RA-Right atrium, RV-Right ventricle)
Fig. 8.19 Four-chambered gated computed tomographic image showing thickened, calcied pericardium (shown by arrow) along the anterior right ventricular wall, biatrial enlargement and tubular right and left ventricles. (LA- Left atrium, LV-Left ventricle, RA-Right atrium, RV-Right ventricle)
b
enables assessment of mediastinal lymphadenopathy (enlargement >10mm), peri­cardial inammation, associated myocardial involvement, if any, and associated haemodynamic effects on the cardiac chambers. It has superior tissue contrast and spatial resolution compared with echocardiography [119, 235]. These characteris­tics are useful in evaluation of the pericardium, for tissue characterization,
114
https://t.me/medicina_free
8 Imaging Studies andHaemodynamics inChronic Constrictive Pericarditis
a
c
b
d
Fig. 8.20 Non-contrast CT images– Axial (a) and coronal (b) showing pericardial thickening and calcication (white arrows); and post-contrast images– four– chamber image (c) showing tubular conguration of both ventricles and biatrial dilation, coronal imaging (d) showing dilated superior and inferior caval veins and hepatic veins (Black arrows)
assessment of inammation, and delineation of the extent of spread of pericardial masses. Although computed tomography may provide better spatial resolution, and detects pericardial calcication accurately, cardiac magnetic resonance avoids the need for iodinated contrast agents, ionizing radiation, or additional image processing.
However, cardiac magnetic resonance cannot be performed in patients with claustrophobia, in presence of contraindications to magnetic resonance imaging such as patients with devices or cardiac implants, metallic coils, severe renal dys­function, and in haemodynamically unstable patients [1115].
(a) Introduction to various imaging sequences
A standard MRI protocol used at All India Institute of Medical Sciences, New Delhi, for pericardial imaging is shown in Table8.1. The procedure takes around 30–40minutes; sequences can be added or removed depending on the requirement and patient’s clinical condition e.g. presence of arrhythmia, and breath-holding capacity.
8.3 Computed Tomography
https://t.me/medicina_free
115
a
b
c
de
Fig. 8.21 Four-chamber images (ac: T1, T2 and LGE respectively)-showing thickened and enhancing pericardium predominantly along right atrium and ventricle, tubular conguration of both ventricles and biatrial dilation; (d) dilated inferior caval vein and hepatic veins; (e) necrotic mediastinal lymph nodes
a
d
Fig. 8.22 Frontal chest radiograph (a) shows plaque-like calcication along the diaphragmatic (white arrowhead) and left border (black arrowhead) areas of the heart. Note is made of right pleu­ral effusion. Four-chamber (b), two-chamber (c) and short axis (d) reconstructions of CT angiog­raphy and volume rendered images (e and f) show extensive pericardial calcication along the diaphragmatic surface and free walls of both ventricles. Note is made of biatrial dilation and tubu­lar ventricles. (LA- Left atrium, LV-Left ventricle, RA-Right atrium, RV-Right ventricle)
b
e
c
f