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10 Continent Ileostomy
167
Fig. 10.11 Conversion of the failed pelvic pouch to continent ileostomy. ( a ) Cross-section of the pelvis with the failed pouch present. ( b ) Segment of bowel to be used to create the continent ileostomy with 15 cm needed for the nipple valve. ( c ) Completed continent ileostomy
There are three options that most readily come to mind for patients with a failing pelvic pouch: (1) it may simply be defunctionalized by a covering ileostomy, (2) revisional sur­gery may be done, and (3) the pouch may be excised. Clearly, the fi rst option is mostly aimed to be just a temporary inter­vention. Refashioning of the pouch and/or the ileoanal anas­tomosis, which may well be tried, is often associated with an unsuccessful result. According to reports in the literature, pouch excision with construction of a conventional ileos­tomy appears to be the most common measure—even in spe-
mended (Fig. 10.11 ). Recent reports [ 61 , 62 ] from well- known colorectal centres confi rm that such a conver­sion is a viable option with encouraging long-term results.
Apart from patients with a problematic conventional ile­ostomy and those unsuitable for a restorative proctocolec­tomy, candidates for a continent ileostomy are also the growing number of patients with a failed ileal pouch-anal anastomosis. It seems reasonable therefore to assume that there may well be a great revival of interest in the continent ileostomy technique in the future.
cialized clinics. This is a very unfortunate decision, however, as such an operation will inevitably be associated with loss of a signifi cant length of terminal ileum. Apart from the

Summary Pearls

practical problems of a “high-fl ow” ileostomy, salt-water imbalance and malabsorbtion of bile acids and vitamin B12 will develop. Given the shortcomings of pouch excision or infi nite diversion, conversion of a failed pouch to a continent ileostomy as suggested by Kusunoki et al. [ 53 ] and Hultén and associates [
54 , 56 ] should be a reasonable alternative.
The terminal ileum is preserved and malabsorbtion conse­quences are avoided. For carefully informed and strongly motivated patients, conversion of the failed ileal pouch-anal anastomosis to a continent ileostomy should be recom-
In summary, the low-pressure intestinal reservoir developed by N. G. Kock is the basis for modern pouch surgery, from continent ileostomy to ileal pouch-anal anastomosis, and remains a viable alternative for select patients to this day. Candidates for a continent ileostomy are patients with poorly functioning conventional ileostomy, patients with ulcerative colitis or familial adenomatous polyposis not suitable for restorative proctocolectomy, or patients with personal pref­erence. A failed pelvic pouch or one that cannot be constructed
168
L. Hultén and H.E. Myrvold
during the operation can also be converted to a continent ileostomy. When performing the procedure, stabilization of the nipple valve and anchoring it to the reservoir wall are the key points in the successful construction of the continent ileostomy. Surgeons caring for these patients should be aware of the early and late complications including ischemic necrosis of the outlet, intra-abdominal abscess, fi stulas, and slippage of the nipple valve resulting in incontinence. Salvage procedures of nipple valve dysfunction and fi stulas are technically demanding and include either rotating the reservoir with construction of a new nipple valve on the for­mer inlet or creating a new nipple valve on a transposed ileal segment. Having a thorough understanding of these concepts will provide valuable insight when faced with the diffi cult clinical situations that these unique patients may pose.

References

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2. Tasker JH. Ileo-cystoplasty: a new technique; an experimental
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19. Ojerskog B, Kock NG, Nilsson LO, Philipson BM, Ahren C. Long­term follow-up of patients with continent ileostomies. Dis Colon Rectum. 1990;33(3):184–9. Epub 1990/03/01.
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22. Nessar G, Fazio VW, Tekkis P, Connor J, Wu J, Bast J, et al. Long­term outcome and quality of life after continent ileostomy. Dis Colon Rectum. 2006;49(3):336–44. Epub 2006/02/02.
23. Hoekstra LT, de Zwart F, Guijt M, Bakx R, Gerhards MF. Morbidity and quality of life after continent ileostomy in the Netherlands. Colorectal Dis. 2009;11(7):719–25. Epub 2009/08/27.
24. Parc Y, Klouche M, Bennis M, Lefevre JH, Shields C, Tiret E. The continent ileostomy: an alternative to end ileostomy? Short and long-term results of a single institution series. Dig Liver Dis. 2011;43(10):779–83. Epub 2011/07/02.
25. Wasmuth HH, Trano G, Endreseth B, Rydning A, Wibe A, Myrvold HE. Long-term surgical load in patients with ileal pouch-anal anas­tomosis. Colorectal Dis. 2009;11(7):711–8. Epub 2009/08/27.
26. de Zeeuw S, Ali UA, Donders RA, Hueting WE, Keus F, van Laarhoven CJ. Update of complications and functional outcome of the ileo-pouch anal anastomosis: overview of evidence and meta­analysis of 96 observational studies. Int J Colorectal Dis. 2012;27(7):843–53. Epub 2012/01/10.
27. Tulchinsky H, Hawley PR, Nicholls J. Long-term failure after restorative proctocolectomy for ulcerative colitis. Ann Surg. 2003; 238(2):229–34.
28. Tekkis PP, Lovegrove RE, Tilney HS, Smith JJ, Sagar PM, Shorthouse AJ, et al. Long-term failure and function after restor­ative proctocolectomy – a multi-centre study of patients from the UK National Ileal Pouch Registry. Colorectal Dis. 2010;12(5): 433–41. Epub 2009/02/20.
29. Ikeuchi H, Uchino M, Matsuoka H, Bando T, Matsumoto T, Tomita N, et al. Surgery for ulcerative colitis in 1,000 patients. Int J Colorectal Dis. 2010;25(8):959–65. Epub 2010/03/11.
30. Hansson BM, Slater NJ, van der Velden AS, Groenewoud HM, Buyne OR, de Hingh IH, et al. Surgical techniques for parastomal hernia repair: a systematic review of the literature. Ann Surg. 2012;255(4):685–95. Epub 2012/03/16.
31. Fazio VW, Church JM. Complications and function of the continent ileostomy at the Cleveland Clinic. World J Surg. 1988;12(2):148–
54. Epub 1988/04/01.
32. Lepisto A, Luukkonen P, Jarvinen HJ. Cumulative failure rate of ileal pouch-anal anastomosis and quality of life after failure. Dis Colon Rectum. 2002;45(10):1289–94.
33. Jarvinen HJ, Makitie A, Sivula A. Long-term results of continent ileostomy. Int J Colorectal Dis. 1986;1(1):40–3. Epub 1986/01/01.
34. Denoya PI, Schluender SJ, Bub DS, Gorfi ne SR, Bauer JJ. Delayed Kock pouch nipple valve failure: is revision indicated? Dis Colon Rectum. 2008;51(10):1544–7. Epub 2008/05/27.
35. Berndtsson IE, Lindholm E, Oresland T, Hulten L. Health-related quality of life and pouch function in continent ileostomy patients: a
10 Continent Ileostomy
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30-year perspective. Dis Colon Rectum. 2004;47(12):2131–7. Epub 2005/01/20.
36. Svaninger G, Nordgren S, Oresland T, Hulten L. Incidence and characteristics of pouchitis in the Kock continent ileostomy and the pelvic pouch. Scand J Gastroenterol. 1993;28(8):695–700. Epub 1993/08/01.
37. Mahadevan U, Sandborn WJ. Diagnosis and management of pou­chitis. Gastroenterology. 2003;124(6):1636–50. Epub 2003/05/23.
38. Cox CL, Butts DR, Roberts MP, Wessels RA, Bailey HR. Development of invasive adenocarcinoma in a long-standing Kock continent ileostomy: report of a case. Dis Colon Rectum. 1997;40(4):500–3. Epub 1997/04/01.
39. Sarigol S, Wyllie R, Gramlich T, Alexander F, Fazio V, Kay M, et al. Incidence of dysplasia in pelvic pouches in pediatric patients after ileal pouch-anal anastomosis for ulcerative colitis. J Pediatr Gastroenterol Nutr. 1999;28(4):429–34. Epub 1999/04/16.
40. Gullberg K, Stahlberg D, Liljeqvist L, Tribukait B, Reinholt FP, Veress B, et al. Neoplastic transformation of the pelvic pouch mucosa in patients with ulcerative colitis. Gastroenterology. 1997;112(5):1487–92. Epub 1997/05/01.
41. Duff SE, O’Dwyer ST, Hulten L, Willen R, Haboubi NY. Dysplasia in the ileoanal pouch. Colorectal Dis. 2002;4(6):420–9.
42. Hulten L, Willen R, Nilsson O, Safarani N, Haboubi N. Mucosal assessment for dysplasia and cancer in the ileal pouch mucosa in patients operated on for ulcerative colitis – a 30-year follow­up study. Dis Colon Rectum. 2002;45(4):448–52. Epub 2002/05/15.
43. Stryker SJ, Carney JA, Dozois RR. Multiple adenomatous polyps arising in a continent reservoir ileostomy. Int J Colorectal Dis. 1987;2(1):43–5. Epub 1987/02/01.
44. Parc YR, Olschwang S, Desaint B, Schmitt G, Parc RG, Tiret E. Familial adenomatous polyposis: prevalence of adenomas in the ileal pouch after restorative proctocolectomy. Ann Surg. 2001;233(3): 360–4. Epub 2001/02/27.
45. Church J. Ileoanal pouch neoplasia in familial adenomatous pol­yposis: an underestimated threat. Dis Colon Rectum. 2005;48(9): 1708–13. Epub 2005/06/07.
46. Alexander JR, Andrews JM, Buchi KN, Lee RG, Becker JM, Burt RW. High prevalence of adenomatous polyps of the duodenal papilla in familial adenomatous polyposis. Dig Dis Sci. 1989; 34(2):167–70. Epub 1989/02/01.
47. Mowat C, Cole A, Windsor A, Ahmad T, Arnott I, Driscoll R, et al. Guidelines for the management of infl ammatory bowel disease in adults. Gut. 2011;60(5):571–607. Epub 2011/04/06.
48. de Oca J, Sanchez-Santos R, Rague JM, Biondo S, Pares D, Osorio A, et al. Long-term results of ileal pouch-anal anastomosis in Crohn’s disease. Infl amm Bowel Dis. 2003;9(3):171–5. Epub 2003/06/07.
49. Bloom RJ, Larsen CP, Watt R, Oberhelman Jr HA. A reappraisal of the Kock continent ileostomy in patients with Crohn’s disease. Surg Gynecol Obstet. 1986;162(2):105–8. Epub 1986/02/01.
50. Hulten L. Proctocolectomy and ileostomy to pouch surgery for ulcer­ative colitis. World J Surg. 1998;22(4):335–41. Epub 1998/04/02.
51. Setti Carraro P, Talbot IC, Nicholls RJ. Long term appraisal of the histological appearances of the ileal reservoir mucosa after restor­ative proctocolectomy for ulcerative colitis. Gut. 1994;35(12): 1721–7. Epub 1994/12/01.
52. Heuschen UA, Allemeyer EH, Hinz U, Lucas M, Herfarth C, Heuschen G. Outcome after septic complications in J pouch proce­dures. Br J Surg. 2002;89(2):194–200. Epub 2002/02/22.
53. Kusunoki M, Sakanoue Y, Shoji Y, Kusuhara K, Yamamura T, Utsunomiya J. Conversion of malfunctioning J pouch to Kock’s pouch. Case report. Acta Chir Scand. 1990;156(2):179–81. Epub 1990/02/01.
54. Hulten L, Fasth S, Hallgren T, Oresland T. The failing pelvic pouch conversion to continent ileostomy. Int J Colorectal Dis. 1992;7(3):119–21. Epub 1992/09/01.
55. Behrens DT, Paris M, Luttrell J. Continent ileostomy can be offered as an option to patients who fail the ileal pouch-anal anastomosis (IPAA). Dis Colon Rectum. 1999;42(5):686.
56. Hulten L. Conversion of a pelvic pouch to a continent pouch (Kock pouch). Tech Coloproctol. 2001;5(3):192. Epub 2002/03/05.
57. Wasmuth HH, Trano G, Wibe A, Endreseth BH, Rydning A, Myrvold HE. Failed pelvic pouch substituted by continent ileos­tomy. Colorectal Dis. 2010;12(7 Online):e109–13. Epub 2009/04/04.
58. Keighley MR, Ogunbiyi OA, Korsgen S. Pitfalls and outcome in ileo-anal pouch surgery for ulcerative colitis. Neth J Med. 1997;50(2):S23–7. Epub 1997/02/01.
59. Setti-Carraro P, Ritchie JK, Wilkinson KH, Nicholls RJ, Hawley PR. The fi rst 10 years’ experience of restorative proctocolectomy for ulcerative colitis. Gut. 1994;35(8):1070–5.
60. Leowardi C, Hinz U, Tariverdian M, Kienle P, Herfarth C, Ulrich A, et al. Long-term outcome 10 years or more after restorative procto­colectomy and ileal pouch-anal anastomosis in patients with ulcerative colitis. Langenbecks Arch Surg. 2010;395(1):49–56. Epub 2009/03/13.
61. Lian L, Fazio VW, Remzi FH, Shen B, Dietz D, Kiran RP. Outcomes for patients undergoing continent ileostomy after a failed ileal pouch-anal anastomosis. Dis Colon Rectum. 2009;52(8):1409–14; discussion 4414–6. Epub 2009/07/21.
62. Wassmuth HH, Myrvold HE, Bengtsson J, Hulten L. Conversion of a failed pouch to a continent ileostomy: a controversy. Colorectal Dis. 2011;13(1):2–5. Epub 2010/12/25.
Part III
The Pelvis

Rectal Prolapse: Current Evaluation, Management, and Treatment of a Historically Recurring Disorder

Dana M. Hayden and Steven D. Wexner
Key Points
• Rectal prolapse is a surgical disorder for which there are a multitude of treatment options; however, con­clusive evidence does not support any one operation as a panacea.
• Symptomology, comorbidities, and previous sur­geries will guide the selection of the appropriate operation for prolapse.
• If a patient is medically fi t, the transabdominal approach should be attempted for both initial and recurrent rectal prolapse, regardless of the initial operation.

Etiology and Epidemiology of Prolapse

Key Concept: Rectal prolapse affects both men and women and may be associated with constipation or fecal inconti­nence. Several anatomic conditions are commonly found with rectal prolapse.
Although an uncommon disorder, full-thickness rectal prolapse can drastically impair the quality of life. It was described as early as 1500 BC, depicting the protrusion of all layers of the rectum through the anal canal into the external environment (Fig. 11.1 ) [ 1 ]. Rectal prolapse can lead to
1 1
several problems including fecal incontinence, obstructed defecation, bleeding, mucosal ulceration, mucous per rec­tum, and, rarely, bowel necrosis from strangulation [ 2 , 3 ]. This disorder is more common in females, especially in the elderly population, although it affects both genders and patients of all ages, with an overall incidence of 4 per 1,000 [ 3 ]. Although prolapse is commonly thought to be associated with multiparty, one-third of females with rectal prolapse are nulliparous [ 4 ]. The peak incidence occurs in the seventh decade for women; interestingly for males with prolapse, it occurs at age 40 years or younger [ 4 ]. Although the exact etiology of prolapse remains unclear, it has been attributed to distal intussusception of the rectum and a combination of associated anatomic factors, including relaxation of the rec­tal suspensory ligaments, chronic straining, altered bowel transit, diastasis of the levator ani, increased width of the retrorectal space, an abnormally deep pouch of Douglas with an associated sliding hernia, and patulous anal sphincter [ 1 , 46 ]. Surgical intervention is the only means of treatment; however, the type of operation still remains controversial, as illustrated by more than 100 different operations.
D. M. Hayden , MD, MPH Department of General Surgery , Loyola University Medical Center , 2160 South First Avenue , Maywood , IL 60153 , USA e-mail: dhayden21@gmail.com
S. D. Wexner , MD, PhD (Hon), FACS, FRCS, FRCS(Ed) ( Department of Colorectal Surgery , Cleveland Clinic Florida , 2950 Cleveland Clinic Blvd. , Weston , FL 33331 , USA e-mail: wexners@ccf.org
S.R. Steele et al. (eds.), Complexities in Colorectal Surgery, DOI 10.1007/978-1-4614-9022-7_11, © Springer Science+Business Media New York 2014
*)
Fig. 11.1 Rectal prolapse
173
174
D.M. Hayden and S.D. Wexner
Evacuatory dysfunction frequently occurs with rectal prolapse and fecal incontinence has been found in approxi­mately 50–75 % of patients with rectal prolapse [ Several factors may contribute to this association: trau­matic stretch of the sphincter complex by the protruding rectum or continuous stimulation of the rectoanal inhibi­tory refl ex by the prolapse resulting in chronic low internal anal sphincter pressures and the presence of a direct con­duit bypassing the sphincter mechanism [ 1 , 4 ]. Interestingly, constipation is also a commonly associated feature of rectal prolapse, reported by 25–50 % of patients [ 4 ]. Although the mechanism is not clear, it appears to be related to diffi culty with defecation due to an obstructing rectal intussuscep­tion, paradoxical puborectalis contraction, or colonic dys­motility [ 1 , 4 ].
1 , 4 ].

Diagnosis and Evaluation

Key Concept: Rectal prolapse is a clinical diagnosis. Underlying symptoms and risk factors should guide the evaluation.
History and physical examination are the key components to the diagnosis of full-thickness rectal prolapse. History and symptoms including persistent or spontaneous prolapse, prolapse with straining, and other symptoms including rec­tal pain, bleeding, mucous secretion, fecal incontinence, and constipation should be ascertained. Previous surgical history including colon resections or anorectal surgery and anorec­tal congenital anomalies repaired during childhood must be documented, as well as medical comorbidities. During the physical examination, reproduction of the prolapse with Valsalva should be performed; status of the anal sphinc­ters, perineal descent, and associated pelvic organ prolapse should also be documented. If the prolapse is not reproduced in the lateral decubitus or prone positions in the offi ce, the patient should sit on a commode and strain.
Adjunctive imaging and testing are not always necessary, but may be helpful. If the prolapse cannot be detected in the offi ce, defecography should be performed. This procedure will also identify some associated pelvic fl oor disorders or defects that may require treatment as well [ 4 ]. A lifelong his- tory of severe constipation should be investigated with colonic transit study and defecography to evaluate for colonic inertia or puborectalis dysfunction; these fi ndings may change the planned operation (total abdominal colec­tomy with rectopexy) or aid in postoperative planning for biofeedback. Colonoscopy should be undertaken before operative intervention according to guidelines for colorectal cancer screening and surveillance as well as to exclude any fi ndings that may change the surgical approach (incidental colon cancer or a tumor serving as lead point for rectal intussusception) [
4 ]. Anorectal physiology testing may not be
helpful since studies have shown that these tests do not reli­ably predict postoperative function after prolapse repair [
4 ].

Types of Operative Repair

Key Concept: Understanding the risks, benefi ts, and techni­cal details of the various approaches for rectal prolapse repair will aid in proper selection of operative repair and help optimize outcomes. In general, functional improvements for both constipation and fecal incontinence occur following both perineal and abdominal repair.
Perineal Operations
Key Concept: Perineal approaches are a second resort, nor­mally to be used only in patients with medical comorbidities that prevent abdominal approaches. Your preferred choice is almost always to perform an Altemeier outside of mucosal or limited full-thickness prolapse where a Delorme may be useful.
Two main perineal operations are currently performed: the Altemeier (perineal rectosigmoidectomy) with or without levatorplasty and with or without colonic J pouch and the Delorme. Anal encirclement procedures, including the Thiersch operation, have for the most part been abandoned due to high complication rates (infection, erosion, breakage) and high recurrence rates [ described in 1900, is performed most commonly for mucosal prolapse or short full-thickness rectal prolapse [ 1 , 4 ]. This operation involves circumferential mucosal sleeve resection of redundant mucosa with imbrication of the muscularis layer and then mucosal anastomosis [ 4 ]. The complete bowel wall is not resected. This perineal operation has been shown to improve incontinence when performed with or without a sphincteroplasty [ 1 ]. It may be technically more challenging than the Altemeier and has been reported to have higher recur­rence rates as well [ 1 ]. Although complications are thought to occur less frequently than with the abdominal approach, uri­nary retention, infection, bleeding, and fecal impaction have been reported in 4–12 % [ 4 ]. Patients will usually have postop- erative improvement of their fecal incontinence (25–70 %) and constipation (13–100 %); however, urgency and tenesmus may occur in a small percentage of patients [ 4 ].
Auffret in France fi rst described perineal rectosigmoidec­tomy in 1882; a series of six cases were published by Mikulicz in 1889 [ 7 ]. Miles popularized the technique in 1933, although it was named after Altemeier, who described the technique with an associated levatorplasty in 1971, reporting a recurrence rate of only 2.8 % [ 2 ]. This operation involves transanal full-thickness resection of the rectum and sigmoid colon (Figs.
1 ]. The Delorme procedure, fi rst
11.2 and 11.3 ). A coloanal anastomosis
11 Rectal Prolapse : Current Evaluation, Management, and Treatment of a Historically Recurring Disorder
175
Fig. 11.2 Rectal prolapse during perineal repair
Fig. 11.4 Hand-sewn coloanal anastomosis during perineal
proctosigmoidectomy
of the levatorplasty appears to decrease short-term recur­rence rates and prolong the recurrence-free interval [
1 ]. The
addition of the colonic J pouch may also improve postopera­tive function. The senor author fi rst described it and routinely employs it [ 8 ]. Some surgeons report low recurrence and morbidity rates with the perineal approach and advocate the Altemeier as the fi rst-line treatment for patients of all ages.
Fig. 11.3 Extraction of rectum and sigmoid during perineal proctosigmoidectomy
is then created with sutures or staples [ 4 ] (Fig. 11.4 ). Some surgeons reserve this perineal repair for older patients with comorbidities since major complications are reported to occur less often than after abdominal operations; the proce­dure can be performed without general anesthesia, and hos­pital stay is shorter [ 4 ]. Complications do occur, including pelvic bleeding, anastomotic leak, abscess, stricture, and bleeding from the anastomosis, but rates are typically less than 12 % [ 1 , 4 ]. In addition, complications related to abdominal operations and pelvic dissection, such as sexual dysfunction, small bowel obstructions, wound infections, and incisional hernias, are avoided with the perineal approach [ 7 ]. Most studies show improvement in continence after peri- neal proctosigmoidectomy with levatorplasty similar to that seen after abdominal operations (20–90 %) [
1 ]. Functional
improvement in constipation is reported in a smaller number of series, with rates ranging from 61 to 100 %. The addition
Abdominal Operations
Key Concept: An abdominal operation, through either an open or minimally invasive approach, is the preferred opera­tion for full-thickness rectal prolapse if the patient’s risk pro­fi le permits. Regardless of the method chosen, adequate mobilization and fi xation at the sacral promontory are required for optimal outcomes.
A variety of abdominal operations are performed to treat rectal prolapse based on the general principles of rectal mobi­lization and suspension of the rectum out of the pelvis. The operations vary by surgical technique (mobilization only, mobilization-rectopexy, mobilization-resection- rectopexy), means of access (laparoscopic or open) and method of fi xa­tion (suture or mesh) [ 9 ]. The extent of dissection, division of the lateral stalks, need for concomitant sigmoid resection, and method of rectal fi xation are variable and remain points of controversy, as no single method has been shown to be more successful than the others and all have associated fail­ures. Laparoscopy has been increasingly used for a variety of the prolapse repairs (including mesh or suture rectopexy and/ or sigmoid resection) with similar recurrence and postopera­tive incontinence and constipation rates when compared to open surgery. Studies evaluating the laparoscopic approach indicate longer operative times but shorter hospital stays and lower overall costs [
1 ].
176
D.M. Hayden and S.D. Wexner
Fig. 11.5 Rectal mobilization during laparoscopic rectopexy
Mobilization of the rectum should extend caudally to the level of the pelvic fl oor musculature, specifi cally to the leva­tor ani muscles, while the extent of lateral mobilization remains controversial (Fig. 11.5 ). In a small study performed by Speakman et al., division of the lateral stalks appeared to be associated with a high rate of postoperative constipation; however, division of the stalks was also found to be associ­ated with decreased recurrence [ 1 , 4 ]. Other studies have shown higher rates of constipation with stalk preservation [ 4 ]. Currently, most surgeons preserve the lateral stalks or may divide one lateral ligament.
The method of fi xation of the rectum is also controversial, manifesting in the multitude of techniques available. Suture rectopexy is commonly performed with the advantage of avoiding the use of a prosthetic mesh, hopefully allowing good fi xation with very little risk of infection or erosion, especially if a resection is performed concomitantly. Fixation with tacks has also been used. Rectopexy with mesh has been described with anterior or posterior placement [ 4 ]. The Ripstein repair and its variations involve placing a synthetic mesh around the mobilized rectum, attaching the mesh to the presacral fascia below the sacral promontory. Studies have shown low recurrence rates as well as improved incontinence in 20–60 % of patients [ 4 ]. Erosion and defecation problems have been noted with the anterior repair, and, accordingly, alternative approaches (attachment to the lateral mesorectum or variety of mesh types) have been used. The Wells mesh rectopexy originally used an Ivalon sponge (polyvinyl alco­hol) with division of the lateral ligaments. The sponge is no longer used due to increased complications and postopera­tive constipation; however, this technique continues to be used with synthetic mesh [
4 ]. Ventral mesh rectopexy (ante-
rior mobilization of rectum) has also been described by D’Hoore et al., in order to decrease postoperative constipa­tion. Orr- Loygue mesh rectopexy mobilizes both the anterior
Fig. 11.6 Laparoscopic suture rectopexy
and posterior rectum before fi xation with mesh. Studies show low recurrence rates (3.4 %) and decreased postopera­tive constipation with ventral rectopexy; however, the rate of new- onset constipation has been reported at approximately 14 % [
4 ]. To date, no randomized trials have compared suture
rectopexy to mesh fi xation.
Concomitant sigmoid resection performed with suture rectopexy was fi rst described by Frykman and Goldberg in 1969 [ 1 ]. The addition of the resection has decreased rates of postoperative constipation, but it does not appear to affect recurrence rates. The addition of a resection to the operation increases the potential risks associated with the transection of bowel and creation of an anastomosis, including anasto­motic leak, abscess, and wound infection.
Laparoscopy and Rectal Prolapse Repair
Key Concept: A minimally invasive approach provides simi­lar outcomes as open surgery, given experience and techni­cal profi ciency, and is increasingly being performed via laparoscopic and robotic means.
The fi rst laparoscopic repair of rectal prolapse (rectopexy) was performed in 1992 [ 4 ]. Since that time, several studies have demonstrated that laparoscopy is safe and feasible for the treatment of prolapse (Figs. 11.6 and 11.7 ). Although these studies are small, they have shown similar recurrence and morbidity rates (4–8 % and 10–33 %, respectively) when compared to the open approach [ 4 ]. The benefi ts of laparos- copy have been reported in several studies. One small ran­domized trial by Solomon et al. found laparoscopy to be associated with less postoperative pain, faster return of bowel function, and shorter hospital stays, although operative times were longer [ 4 , 10 ]. A meta-analysis performed in 2005 com- pared open to laparoscopic abdominal rectopexy [
3 ]. This
11 Rectal Prolapse : Current Evaluation, Management, and Treatment of a Historically Recurring Disorder
177
Fig. 11.7 Suture placement during robotically-assisted suture rectopexy
group found that operative time was longer for laparoscopy, but length of stay was shorter. However, overall recurrence was found to be similar between open and laparoscopic abdominal rectopexy with a mean follow-up time of 12–31 months for the included studies [
3 ]. Byrne et al. investi-
gated long-term functional outcomes between laparoscopic rectopexy and open and resection-rectopexy. They found that the recurrence rate remains low (7 % at 5 years and 11 % at 10 years follow-up) and that improvement of post­operative incontinence and constipation is similar when compared to the other operations; the majority of patients felt as if their constipation improved after surgery, and incontinence scores had improved [ 11 ]. The rate of wound complications also appeared to be lower in the laparoscopic group [ 4 ].
Robotic surgery has also been applied to the treatment of rectal prolapse (Fig. 11.7 ). There have been only a few series with small numbers reported. One small nonrandom­ized trial reported longer operating time and higher costs, but robotic-assisted mesh rectopexy was found to be safe and feasible [ 12 ]. Nonetheless, the visualization and ease of suturing during robotic surgery appears improved compared to conventional laparoscopy [ 4 , 12 ]. Non-resectional recto- pexy may be one of the better indications for robotic surgery as the procedure requires only a single docking of the robot and no incision is necessary for specimen retrieval. Moreover, unlike using laparoscopic instruments to suture the rectum to the anterior sacral fascia and periosteum, this step may potentially be reliably undertaken with the robotic platform.

Recurrence After Initial Repair

Key Concept: Recurrence rates increase with longer follow­ up intervals and are typically higher with perineal proce­dures. An abdominal repair should be the initial approach
when the patient’s risk profi le permits, while the type of pro­cedure (i.e., rectopexy alone, mesh, resection) does not seem to infl uence recurrence rates.
Recurrence after initial prolapse repair has been reported to occur in 2–60 % of patients. These recurrence rates vary with type of approach, technique, preoperative anorectal and pelvic anatomy and function, and length of follow-up among other variables. Most studies have shown lower recurrence rates for abdominal repairs; whereas the reasons for this dif­ference are not exactly clear, it is likely due to inadequate mobilization and resection of the rectum and sigmoid that results from lack of direct visualization during the perineal approach. Several studies have tried to identify predictors of recurrence. To date, there is very little conclusive evidence identifying specifi c risk factors. It is possible that rectal pro­lapse is just one symptom of overall pelvic fl oor dysfunction, which may recur if the overall pelvic environment is not changed.
Recurrence After Altemeier Procedure
Key Concept: The wide range of reported recurrence rates following an Altemeier are likely multifactorial and include technical variables (i.e., small resected segment, failure to enter the peritoneal cavity) and patient-driven factors (prior surgery, length of follow-up).
Several studies have examined the recurrence rates after perineal rectosigmoidectomy. In a literature review, the range of recurrence rates found for the Altemeier procedure was between 0 and 58 % [ 2 ]. In a study performed by Altomare et al., 17 (18 %) of 93 patients experienced com­plete recurrence after being followed for at least 12 months (median 41, 12–112). Six other patients had recurrence of mucosal prolapse only [ 2 ]. Of the 17 patients with full- thickness recurrence, repeat Altemeier was performed in 6, Delorme in 1, and Wells mesh rectopexy in 1; the 9 patients refused further surgery [ previous surgery for prolapse was associated with higher recurrence; other factors such as duration of follow-up, length of resected specimen, levatorplasty, age, sex, and severity of incontinence were not signifi cantly associated [
2 ]. At Washington University in St. Louis, Glasgow et al.
found a recurrence rate of 8.5 % when 106 consecutive patients with full-thickness rectal prolapse had perineal proctectomy performed regardless of preoperative status (age, comorbidities, previous abdominal or anorectal sur­gery). In a study by Cirocco et al. published in 2010, 103 consecutive patients with full-thickness rectal prolapse were treated with perineal proctosigmoidectomy between 2000 and 2009. The authors reported that 61 % of patients had pre­operative constipation; 94 % of these patients had improve­ment. Forty-seven percent had fecal incontinence, which
2 ]. These authors found that only
178
D.M. Hayden and S.D. Wexner
improved in 85 % of patients following surgery [ 7 ]. This group found no recurrences with a mean follow-up of 43 months [
7 ]. In their discussion, the authors allude to their
lack of understanding regarding the historically high recur­rence rates reported after perineal repair. Interestingly, in their literature review, cumulative recurrence rate was 37 % for studies performed before 1971 and only 10 % in reports published after 1971 [ 7 ]. The higher rates of recurrence were suspected to be due to poor surgical technique, especially in those cases where the mobilization failed to enter the perito­neal cavity.
Several studies have reported lower recurrence and improved outcomes after abdominal repair. Only one small randomized trial compared the perineal to transabdominal approach. Abdominal resection-rectopexy with pelvic fl oor repair was compared to perineal rectosigmoidectomy with pelvic fl oor repair in 20 elderly female patients with full­thickness rectal prolapse and fecal incontinence (10 patients in each arm) [ 13 ]. There were no recurrences following resection-rectopexy and only one after rectosigmoidectomy. Continence, frequency of defecation, maximal resting pres­sure, and compliance all appeared to improve more after resection-rectopexy versus perineal proctosigmoidectomy [ 13 ]. However, according to a Cochrane review by Bachoo et al. in 2000, which was updated by Tou et al. in 2008, no conclusive data indicate that the abdominal approach is superior to the perineal approach [ 14 , 15 ]. This conclusion is likely due to the small number and size of randomized trials directly comparing both approaches. Perineal proctosig­moidectomy continues to constitute 50–60 % of operations conducted for rectal prolapse [ 15 ].
Recurrence After Abdominal Approach
Key Concept: Recurrence rates are similar among the vari­ous abdominal operations and in general are <10 % in sin­gle institutional studies, with larger series demonstrating higher rates at extended follow-up intervals.
In 2005, the Rectal Prolapse Recurrence Study Group eval­uated recurrence of full-thickness rectal prolapse after abdom­inal operations [ 9 ]. They examined the individual pooled data for 643 patients. Overall recurrence was 1 %, 6 %, and almost 29 % at 1-, 5-, and 10-year follow-up, respectively, regardless of the method employed [ 9 ]. The surgical technique, means of access, and method of rectopexy all had no signifi cant effect on recurrence [ 9 ]. Interestingly, the degree of complexity of the operation also did not infl uence recurrence (mobilization alone had similar recurrence compared to resection-rectopexy)
9 ]. Long-term recurrence rates were almost 30 % after 10
[ years, much higher than some proponents of the abdominal approach have reported in the short term.
In 2011, the Standards Practice Task Force of the American Society of Colon and Rectal Surgeons published
practice parameters for rectal prolapse based on studies and trials performed between 1978 and 2010. Recommendations were formulated and graded on quality of evidence. This task force indicated that for patients who are acceptable surgical candidates, transabdominal rectal fi xation should be the procedure of choice for rectal pro­lapse [
4 ]. This recommendation was “strong, based on
moderate quality evidence” that described the transabdom­inal approach as generally superior, reporting recurrence rates four times higher and postoperative function worse for perineal proctosigmoidectomy [ 4 ]. Similar to the report of Raftopoulos et al., this group noted that type of rectal fi xation did not signifi cantly infl uence recurrence. They noted recurrence after suture rectopexy to occur in 3–9 % of patients [ 4 ], reporting that worsening of preoperative constipation or new-onset constipation can occur with suture rectopexy [
4 ]. This task force also indicated that the
addition of resection to rectopexy was associated with lower recurrence and improved function for patients with preoperative constipation. Recurrence rates after resec­tion-rectopexy were noted to be 2–5 %. However, compli­cations were higher, likely due to associated anastomotic complications. It does appear that improvement of fecal incontinence after resection-rectopexy is less than seen without sigmoid colectomy [
4 ].
Recurrence rates are also low for mesh rectopexy. Although higher morbidities did result from erosion or infec­tion, recurrence was reported to be only 2.3–5 % [ 4 ]. A study performed at Cleveland Clinic by Hool et al. investigated recurrent rectal prolapse, management, and risk factors. They reported on 24 patients who were operated on for recurrent rectal prolapse out of 234 patients seen for prolapse from 1963 to 1993. Median time to recurrence was 2 years; however, 30 % occurred within 7 months of the initial opera­tion [ 6 ]. The cause of recurrence was identifi ed in 12 of the 24 patients; 11 were found to be associated with mesh used during the initial Ripstein repair (mesh pulled off from the rectum or sacrum, loose sling, misplacement or removal of mesh for pain) [ 6 ]. The majority of repairs for recurrent pro- lapse were performed transabdominally; only one patient had recurrence after the second repair (who also recurred after a third operation) [ 6 ].

Types of Operations for Recurrence

Key Concept: An abdominal repair should be the preferred approach, whenever possible, for recurrent prolapse patients. Any prior anastomosis should be resected when performing a second repair that involves a resection. You should exercise caution when considering early surgical intervention in patients with functional problems following abdominal pro­lapse repairs and rely instead on bowel regimen adjustments, bowel training, and time.