Liver transplantation (LT) has turned from a dream into a reality. The rst attempts of canine LT covered a one-page short letter by St.Welch in 1955 in the ‘Transplantation Bulletin,’ a supplement of the Journal of Plastic and Reconstructive Surgery. At that time, a transplantation jour­nal did even not exist! Later on, it was discovered that the Milanese surgeon V.Staudacher had realized the rst experi­ments in 1952. Starzl’s large animal experience resulted in the “rst LT experiment in human” on March 26, 1963 [1]. Twenty years later, the National Institute of Health Consensus Development Conference based on only 540 LTs performed in Denver-Pittsburgh, Hannover, Cambridge, and Groningen, concluded that LT was “a promising alternative to current therapy in the management of late phase of several forms of severe liver diseases.” Moreover, the Committee declared that LT had the potential to become a “clinical service” instead of an experimental procedure. This consensus con­ference’s results represented the starting point for the high­speed implementation of LT as a curative treatment of many livers and liver-based diseases [1–4]. From 1960 to 1990, knowledge was almost exclusively based on deceased donor LT experiences. From 1990 onwards, living donor LT (LDLT) expanded further knowledge about surgical tech­nique, physiology, and peri-operative care [5]. The LDLT experience will undoubtedly lead to the full development of all other technical LT variants, badly needed to overcome allograft shortage and optimize liver recipients’ surgical and medical care [5].