However, frequent patient follow-up is critical to identify early blisters or ulcers that require debridement or plastic surgery. Consultation by the plastic surgeon is recommended after extrav­asation of large volume vesicles, when a patient is in severe pain or if healing has not occurred within 1–3weeks after extravasation. A conser­vative approach is not appropriate if the child has persistent pain, edema and erythema, blistering, and necrosis which may hide an ulcer covered with enlarged eschar. In case of delay in treat­ment, permanent functional damage can occur due to a prolonged tissue exposure. When a sur­gical procedure is not performed at the proper time repeated debridement are required, larger excision is usually necessary, and partial thick­ness skin grafting or ap reconstruction are man­datory actions. The complex of clinical manifestations related to an increase in tissue pressure within a non-compressible space such as that of the muscle lodges covered by their own fascia is called as compartment syndrome. Compartment pressure measurement is useful in evaluating questionable compartment syndrome or in patients who have sensory blunting or are under general anesthesia. Normal pressure in a muscle compartment is less than 10–20mmHg.

Immediate surgical management consists of two most frequently reported manoeuvers: post inci­sional washing and local debridement. However, signs of tissue and nervous ischemic damage and the rigidity of the limbs and extremities in griposis must be avoided promptly, since the cosmetic and functional sequelae arise very quickly. Fasciotomy is the only accepted treatment of compartment syn­drome and should be performed quickly after the diagnosis is made. Outcomes after fasciotomy are best when there is no delay in treatment. In few words, all observational and decision-making activ­ities must be taken with great timeliness and with­out time delays [32–34].