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an island of stomach tissue that was previously stripped of its
blood supply from the left gastroepiploic artery and now loses
more blood ow generated from the left gastric artery. As such, it
is at risk of ischemia, and an evaluation with ICG may also be
useful in this situation in determining the need for resection
(Video 7.7). Following the gastric pouch formation, assuming no
ischemia concerns exist, a GJ and jejunojejunal anastomosis is
then created. After the new GJ anastomosis is constructed, ICG is
placed inside the stomach lumen to verify the integrity of the GJ
anastomosis. The leak test is performed in the same method as it
was previously explained during primary RYGB operations.
E. B. Chen et al.
Revision ofGJ Anastomosis
Marginal ulcers are a known complication after RYGB.The rate
of marginal ulcers ranges from 0.6% to 25% [74]. Though most
marginal ulcers resolve with medical and endoscopic therapies,
surgery is required for refractory marginal ulcers. Rates of reoperation for marginal ulcers are as high as 32% [75]. Refractory
marginal ulcers are typically surgically corrected with a resection
of the GJ anastomosis and jejunum with recreation of the GJ anastomosis or formation of an esophagojejunostomy. Given the reoperative nature in a hostile, inammatory area, the rate of
complications from this type of surgery is considerable compared
to primary bariatric surgery. In a small study by Chau etal., 25%
of patients who required revisional surgery for marginal ulcers
had a postoperative complication that required a reoperation [76].
Patel etal. indicated a 5% chance of anastomotic leak [75]. In
these high-risk anastomoses, ICG may again be benecial when
given intraluminally to ensure the integrity of the new GJ anastomosis and potentially reduce the incidence of complications.
Intraluminal ICG would be delivered in the same solution and
manner as described previously in this chapter. Intravenous ICG
can also be used to assess perfusion of the GJ (Video 7.8) and
gastric pouch during revisional surgery (Video 7.9).
Novel Fluorescence-Guided Gastric Calibration Tube
The Endolumik Fluorescence-Guided Gastric Calibration Tube
(Figs.7.1 and 7.2) is a novel single-use, uorescence-guided calibration tube indicated for use in bariatric, gastric, and esophageal

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Fig. 7.1 The Endolumik Fluorescence-Guided Gastric Calibration Tube
after turning on NIR lighting system, white light view
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surgery to improve visualization of tube position and to serve as a
sizing and measurement guide, for the application of suction, gastric decompression/drainage of gastric uids, and irrigation and
leak testing [77]. This device combines the functionality of a
nasogastric or orogastric tube, a calibration tube, and a leak testing system. The device was designed to improve intraoperative
visualization and provide surgeons with additional visual cues to
identify anatomic structures and delineate tissue planes with the
goal of improving the precision of surgical dissection.
The Endolumik Gastric Calibration Tube is lit using NIR spectrum LEDs which enable transillumination through esophagogastric tissues. The tube is 80cm long and is available in two different
diameters: 36 and 40 French. It has a rounded tip and small side
holes at the distal end to enable gastric decompression and/or
irrigation. The proximal end includes a handle with an integral
suction regulator. An additional squeeze bulb with pressure gauge
may be attached to the end of the regulator to perform leak testing.
Pilot studies have been completed using the device to improve
visualization during laparoscopic sleeve gastrectomy and laparoscopic gastric bypass (Figs. 7.3, 7.4 and 7.5). The three black

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E. B. Chen et al.
Fig. 7.2 The Endolumik Fluorescence-Guided Gastric Calibration Tube
after turning on NIR lighting system, NIR light view
stripes at the distal end of the device enable uorescence-guided
measurement of up to 10cm of length (Fig.7.6). The device was
FDA approved on March 3, 2023, via the 510K pathway. It is the

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Fig. 7.3 Use of the Endolumik Fluorescence-Guided Gastric Calibration
Tube during gastric sleeve construction
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Fig. 7.4 Fluorescence-guided gastric sleeve construction during sleeve gastrectomy operation using the Endolumik calibration tube
rst device to be approved through the Safer Technologies
Program (STeP) [78], a voluntary program for medical devices
that are reasonably expected to signicantly improve the safety of
currently available treatments.

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Fig. 7.5 Fluorescence-guided gastric pouch construction during gastric
bypass operation using the Endolumik calibration tube
E. B. Chen et al.
Fig. 7.6 Use of the Endolumik Fluorescence-Guided Gastric Calibration
Tube to make uorescence-guided measurements of gastric pouch length during gastric bypass

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Pearls andPitfalls
• Transillumination device which provides enhanced
intraoperative visualization to enable more precise surgical
dissection.
• Combines functionality of orogastric tube, calibration tube,
and leak testing system.
• Compatible with all NIR surgical camera systems.
• LED-powered NIR device obviates the need for ICG dye
injection.
Conclusion
Bariatric surgery is a powerful tool for treating obesity and its
associated comorbidities. Sleeve gastrectomy (SG), Roux-en-Y
gastric bypass (RYGB), and biliopancreatic diversion with duodenal switch (BPD/DS) are the main primary operations. The number of revisional bariatric surgeries continues to grow and often
involves creation of a gastrojejunostomy. ICG has emerged as a
useful tool in assessing perfusion and the integrity of the tissue
perfusion and anastomoses in these surgeries. Further investigation into the application of intraoperative uorescence guidance
will make the primary and revisional bariatric surgeries a safer
and more effective option for patients.
Conicts of Interest None.
References
1. The National Institutes of Health (NIH) Consensus Development
Program: Gastrointestinal Surgery for Severe Obesity. https://consensus.
nih.gov/1991/1991gisurgeryobesity084html.htm. Accessed 11 Sep 2021.
2. Estimate of Bariatric Surgery Numbers, 2011–2019 | American Society
for Metabolic and Bariatric Surgery. https://asmbs.org/resources/
estimate- of- bariatric- surgery- numbers. Accessed 5 Sep 2021.

224
https://t.me/medicina_free
3. Ren CJ, Patterson E, Gagner M.Early results of laparoscopic biliopancreatic diversion with duodenal switch: a case series of 40 consecutive
patients. Obes Surg. 2000;10:514–23.
4. Brethauer SA.Sleeve gastrectomy. Surg Clin N Am. 2011;91:1265–79.
5. Brethauer SA, Hammel JP, Schauer PR.Systematic review of sleeve gastrectomy as staging and primary bariatric procedure. Surg Obes Relat
Dis. 2009;5:469–75.
6. Dixon JB, McPhail T, O’Brien PE.Minimal reporting requirements for
weight loss: current methods not ideal. Obes Surg. 2005;15:1034–9.
7. Rosenthal RJ. International sleeve gastrectomy expert panel consensus
statement: best practice guidelines based on experience of >12,000 cases.
Surg Obes Relat Dis. 2012;8:8–19.
8. Gagner M, Hutchinson C, Rosenthal R. Fifth International Consensus
Conference: current status of sleeve gastrectomy. Surg Obes Relat Dis.
2016;12:750–6. https://doi.org/10.1016/j.soard.2016.01.022.
9. Zellmer JD, Mathiason MA, Kallies KJ, Kothari SN. Is laparoscopic
sleeve gastrectomy a lower risk bariatric procedure compared with laparoscopic roux-en-Y gastric bypass? A meta-analysis. Am J Surg.
2014;208:903–10.
10. Rebecchi F, Allaix ME, Giaccone C, Ugliono E, Scozzari G, Morino
M. Gastroesophageal reux disease and laparoscopic sleeve gastrectomy: a physiopathologic evaluation. Ann Surg. 2014;260:909–15.
11. Himpens J, Dobbeleir J, Peeters G. Long-term results of laparoscopic
sleeve gastrectomy for obesity. Ann Surg. 2010;252:319–24.
12. Lauti M, Kularatna M, Hill AG, Maccormick AD.Weight regain following sleeve gastrectomy—a systematic review. Obes Surg. 2016;26:1326–
34.
13. Landreneau JP, Strong AT, Rodriguez JH, Aleassa EM, Aminian A,
Brethauer S, Schauer PR, Kroh MD.Conversion of sleeve gastrectomy to
Roux-en-Y gastric bypass. Obes Surg. 2018;28:3843–50.
14. Aurora A, Khaitan L, Saber A.Sleeve gastrectomy and the risk of leak: a
systematic analysis of 4,888 patients. Surg Endosc. 2012;26:1509–15.
15. Silecchia G, Iossa A.Complications of staple line and anastomoses following laparoscopic bariatric surgery. Ann Gastroenterol. 2018;31:56.
16. Berger ER, Clements RH, Morton JM, Huffman KM, Wolfe BM, Nguyen
NT, Ko CY, Hutter MM.The impact of different surgical techniques on
outcomes in laparoscopic sleeve gastrectomies: the rst report from the
metabolic and bariatric surgery accreditation and quality improvement
program (MBSAQIP). Ann Surg. 2016;264:464–71.
17. Gagner M, Buchwald JN. Comparison of laparoscopic sleeve gastrectomy leak rates in four staple-line reinforcement options: a systematic
review. Surg Obes Relat Dis. 2014;10:713–23.
18. Baker RS, Foote J, Kemmeter P, Brady R, Vroegop T, Serveld M. The
science of stapling and leaks. Obes Surg. 2004;14:1290–8.
E. B. Chen et al.

7 Use ofFluorescence Guidance inBariatric Surgery
https://t.me/medicina_free
19. Hughes D, Hughes I, Khanna A.Management of staple line leaks following sleeve gastrectomy—a systematic review. Obes Surg. 2019;29:2759–
72.
20. Giuliani A, Romano L, Marchese M, Necozione S, Cianca G, Schietroma
M, Carlei F.Gastric leak after laparoscopic sleeve gastrectomy: management with endoscopic double pigtail drainage. A systematic review. Surg
Obes Relat Dis. 2019;15:1414–9.
21. Alander JT, Kaartinen I, Laakso A, Pätilä T, Spillmann T, Tuchin VV,
Venermo M, Välisuo P.A review of Indocyanine green uorescent imaging in surgery. Int J Biomed Imaging. 2012;2012:1. https://doi.
org/10.1155/2012/940585.
22. Benya R, Quintana J, Brundage B. Adverse reactions to indocyanine
green: a case report and a review of the literature. Cathet Cardiovasc
Diagn. 1989;17:231–3.
23. Olmi S, David G, Cesana G, Ciccarese F, Giorgi R, de Carli S, Uccelli
M. Modied sleeve gastrectomy combined with laparoscopic Rossetti
fundoplication and vascularization assessment with Indocyanine green.
Obes Surg. 2049;29:3086–8.
24. Frattini F, Lavazza M, Mangano A, Amico F, Rausei S, Rovera F, Boni L,
Dionigi G. Indocyanine green-enhanced uorescence in laparoscopic
sleeve gastrectomy. Obes Surg. 2015;25:949–50.
25. Ortega CB, Guerron AD, Yoo JS.The use of uorescence angiography
during laparoscopic sleeve gastrectomy. JSLS. 2018;22:e2018.00005.
https://doi.org/10.4293/JSLS.2018.00005.
26. di Furia M, Romano L, Salvatorelli A, Brandolin D, Lomanto D, Cianca
G, Schietroma M, Carlei F, Giuliani A. Indocyanine green uorescent
angiography during laparoscopic sleeve gastrectomy: preliminary results.
Obes Surg. 2019;29:2786–90.
27. Billy H, Jones G.Indocyanine green mesenteric angiography as an intraoperative assessment of bowel perfusion in revisional and primary bariatric operations. Assessment of 50 cases, operative ndings, and surgical
interventions taken. Surg Obes Relat Dis. 2019;15:S228.
28. Hagen ME, Diaper J, Douissard J, Jung MK, Buehler L, Aldenkortt F,
Barcelos GK, Morel P. Early experience with intraoperative leak test
using a blend of methylene blue and Indocyanine green during robotic
gastric bypass surgery. Obes Surg. 2019;29:949–52.
29. Kalmar CL, Reed CM, Peery CL, Salzberg AD.Intraluminal indocyanine
green for intraoperative staple line leak testing in bariatric surgery. Surg
Endosc. 2020;34:4194–9.
30. Sethi M, Zagzag J, Patel K, etal. Intraoperative leak testing has no correlation with leak after laparoscopic sleeve gastrectomy. Surg Endosc.
2016;30:883–91.
31. Bingham J, Lallemand M, Barron M, Kuckelman J, Carter P, Blair K,
Martin M.North Pacic surgical association routine intraoperative leak
225

226
https://t.me/medicina_free
testing for sleeve gastrectomy: is the leak test full of hot air? Am J Surg.
2016;211:943–7.
32. Ignat M, Vix M, Imad I, D’Urso A, Perretta S, Marescaux J, Mutter
D.Randomized trial of Roux-en-Y gastric bypass versus sleeve gastrectomy in achieving excess weight loss. Br J Surg. 2017;104:248–56.
33. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K,
Schoelles K. Bariatric surgery: a systematic review and meta-analysis.
JAMA. 2004;292:1724–37.
34. Schauer PR, Bhatt DL, Kirwan JP, etal. Bariatric surgery versus intensive
medical therapy for diabetes—5-year outcomes. N Engl J Med.
2017;376:641–51.
35. Aminian A, Brethauer SA, Andalib A, etal. Individualized metabolic surgery score: procedure selection based on diabetes severity. Ann Surg.
2017;266:650–7.
36. Pallati PK, Shaligram A, Shostrom VK, Oleynikov D, Mcbride CL,
Goede MR.Improvement in gastroesophageal reux disease symptoms
after various bariatric procedures: review of the bariatric outcomes longitudinal database. Surg Obes Relat Dis. 2014;10:502–7.
37. Peterli R, Wolnerhanssen BK, Peters T, et al. Effect of laparoscopic
sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight
loss in patients with morbid obesity: the SM-BOSS randomized clinical
trial. JAMA. 2018;319:255–65.
38. Bendewald FP, Choi JN, Blythe LS, Selzer DJ, Ditslear JH, Mattar
SG.Comparison of hand-sewn, linear-stapled, and circular-stapled gastrojejunostomy in laparoscopic Roux-en-y gastric bypass. Obes Surg.
2004;21:1671. https://doi.org/10.1007/s11695- 011- 0470- 6.
39. Sundaresan N, Sullivan M, Hiticas BA, etal. Impacts of gastrojejunal
anastomotic technique on rates of marginal ulcer formation and anastomotic bleeding following Roux-en-Y gastric bypass. Obes Surg.
2021;31:2921–6.
40. Smith MD, Adeniji A, Wahed AS, etal. Technical factors associated with
anastomotic leak after Roux–en–Y gastric bypass. Surg Obes Relat Dis.
2015;11:313–20.
41. Ballesta C, Berindoague R, Cabrera M, Palau M, Gonzales
M.Management of anastomotic leaks after laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2008;18:623–30.
42. Grifth PS, Birch DW, Sharma AM, Karmali S.Managing complications
associated with laparoscopic Roux-en-Y gastric bypass for morbid obesity. Can J Surg. 2012;55:329.
43. Gonzalez R, Sarr MG, Smith D, Baghai M, Kendrick M, Szomstein S,
Rosenthal R, Murr MM. Diagnosis and contemporary management of
anastomotic leaks after gastric bypass for obesity. J Am Coll Surg.
2007;204:47–55.
44. Kim J, Azagury D, Eisenberg D, DeMaria E, Campos GM.ASMBS position statement on prevention, detection, and treatment of gastrointestinal
E. B. Chen et al.

7 Use ofFluorescence Guidance inBariatric Surgery
https://t.me/medicina_free
leak after gastric bypass and sleeve gastrectomy, including the roles of
imaging, surgical exploration, and nonoperative management. Surg Obes
Relat Dis. 2015;11:739–48.
45. de Moura DTH, de Moura BFBH, Manfredi MA, Hathorn KE, Bazarbashi
AN, Ribeiro IB, de Moura EGH, Thompson CC. Role of endoscopic
vacuum therapy in the management of gastrointestinal transmural defects.
World J Gastrointest Endosc. 2019;11:329–44.
46. Carter JT, Tafreshian S, Campos GM, Tiwari U, Herbella F, Cello JP, Patti
MG, Rogers SJ, Posselt AM.Routine upper GI series after gastric bypass
does not reliably identify anastomotic leaks or predict stricture formation.
Surg Endosc Other Interv Tech. 2007;21:2172–7.
47. Lee SD, Khouzam MN, Kellum JM, DeMaria EJ, Meador JG, Wolfe LG,
Maher JW.Selective, versus routine, upper gastrointestinal series leads to
equal morbidity and reduced hospital stay in laparoscopic gastric bypass
patients. Surg Obes Relat Dis. 2007;3:413–6.
48. Hess DS, Hess DW. Biliopancreatic diversion with a duodenal switch.
Obes Surg. 1998;8:267–82.
49. Sethi M, Chau E, Youn A, Jiang Y, Fielding G, Ren-Fielding C.Surgery
for long-term outcomes after biliopancreatic diversion with and without
duodenal switch: 2-, 5-, and 10-year data. Surg Obes Relat Dis.
2016;12:1697–705.
50. Biertho L, Simon-Hould F, Marceau S, Lebel S, Lescelleur O, Biron
S.Current outcomes of laparoscopic duodenal switch. Ann Surg Innov
Res. 2016;10:1.
51. Mingrone G, Panunzi S, de Gaetano A, etal. Bariatric surgery versus
conventional medical therapy for type 2 diabetes. N Engl J Med.
2012;366:1577–85.
52. Scopinaro N, Adami GF, Marinari GM, Gianetta E, Traverso E, Friedman
D, Camerini G, Baschieri G, Simonelli A. Biliopancreatic diversion.
World J Surg. 1998;22:936–46.
53. Albaugh VL, Banan B, Antoun J, Xiong Y, Guo Y, Ping J, Alikhan M,
Clements BA, Abumrad NN, Flynn CR.Role of bile acids and GLP-1in
mediating the metabolic improvements of bariatric surgery.
Gastroenterology. 2019;156:1041–1051.e4.
54. Raghow R. Ménage-à-trois of bariatric surgery, bile acids and the gut
microbiome. World J Diabetes. 2015;6:367.
55. Albaugh VL, Banan B, Ajouz H, Abumrad NN, Flynn CR.Bile acids and
bariatric surgery. Mol Aspects Med. 2017;56:75–89.
56. Sánchez-Pernaute A, Rubio Herrera MA, Pérez-Aguirre E, García Pérez
JC, Cabrerizo L, Díez Valladares L, Fernández C, Talavera P, Torres
A.Proximal duodenal-ileal end-to-side bypass with sleeve gastrectomy:
proposed technique. Obes Surg. 2007;17:1614–8.
57. Yashkov Y, Bordan N, Torres A, Malykhina A, Bekuzarov D.SADI-S 250
vs roux-en-Y duodenal switch (RY-DS): results of 5-year observational
study. Obes Surg. 2021;31:570–9.
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