- •Table of Contents
- •Case Studies
- •Volume 2 Stephen m. Stahl
- •Thomas l. Schwartz
- •It furthers the University’s mission by disseminating knowledge in the pursuit of education, learning and research at the highest international levels of excellence.
- •Information on this title: www.Cambridge.Org/9781107607330
- •Illness – Chemotherapy – Examinations, questions, etc. |
- •Isbn 978-1-107-60733-0 Paperback
- •Introduction
- •Learning objectives
- •Accreditation and credit designation statements
- •Optional posttest and cme credit instructions (see p. 441) Peer review
- •Disclosures
- •Authors/developers
- •Disclosure of off-label use
- •Disclaimer
- •Cultural and linguistic competency
- •Provider
- •Support
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Case outcome: second interim follow-up visit at two months
- •Attending physician’s mental notes: interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 12 months
- •Case outcome: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Psychotherapy moment
- •Psychopharmacology components
- •Psychotherapy
- •Documentation
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through six months
- •Question
- •Attending physician’s mental notes: nine months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: nine-month follow-ups
- •Question
- •Attending physician’s mental notes: interim follow-up through nine months (continued)
- •Case outcome and multiple interim follow-ups to 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Tardive dyskinesia
- •Tardive dyskinesia facts
- •Tardive dyskinesia treatments
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through four months
- •Question
- •Attending physician’s mental notes: nine months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: 9–12 month follow-ups
- •Question
- •Case outcome: interim follow-ups through 12 months
- •Case outcome: multiple interim follow-ups through 16 months
- •Attending physician’s mental notes: 16-month follow-ups
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Abnormal Involuntary Movement Scale (aims)
- •Aims instructions
- •Case outcome: use of outcome measures
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Question
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four months
- •Question
- •Case outcome: interim follow-ups through six months
- •Attending physician’s mental notes: interim follow-up, nine months (continued)
- •Case outcome and multiple interim follow-ups to 12–120 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment How does vns theoretically work?
- •Vns side effects
- •Neurostimulation and neuromodulatory devices other than vns
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through one month
- •Question
- •Case outcome: interim follow-ups through two months
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four-month follow-ups
- •Question
- •Case outcome: interim follow-ups through four months (continued)
- •Attending physician’s mental notes: interim follow-ups through four months
- •Case outcome and multiple interim follow-ups to six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Is quetiapine (Seroquel) an antipsychotic, anti-manic, antidepressant, anxiolytic, or a hypnotic?
- •Pharmacodynamics of quetiapine and norquetiapine
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through one month
- •Case outcome: interim follow-ups through two months
- •Attending physician’s mental notes: two months
- •Question
- •Case outcome: interim follow-ups through two months
- •Case outcome: interim follow-ups through three months
- •Question
- •Case outcome and multiple interim follow-ups up to six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Pharmacodynamic moment
- •What is worse in causing escalated mania or mixed features, antidepressants or stimulants?
- •Should unipolar antidepressants be used in bipolar disorder?
- •Does clonazepam (Klonopin) work in bipolar mania?
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Question
- •Case outcome
- •Case debrief
- •Take-home points
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four months
- •Case outcome: interim follow-ups through six months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: nine-month follow-ups
- •Attending physician’s mental notes: interim follow-up, nine months (continued)
- •Case outcome and multiple interim follow-ups to 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Treating aawg with metformin
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through six months
- •Attending physician’s mental notes: six months
- •Case outcome: interim follow-ups through nine months
- •Case outcome: interim follow-ups through 18 months
- •Attending physician’s mental notes: through 20 months
- •Question
- •Case outcome: interim follow-ups through 24 months
- •Question
- •Attending physician’s mental notes: 24-month follow-ups
- •Case outcome: interim follow-up, 36 months
- •Attending physician’s mental notes: 48-month follow-ups
- •Question
- •Case outcome and multiple interim follow-ups to 48 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Techniques for switching antipsychotics
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Question
- •Case outcome
- •Case debrief
- •Clozapine sialorrhea statistics and etiology
- •Possible antidotes for cis
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through three months
- •Attending physician’s mental notes: six months
- •Case outcome: interim follow-ups through nine months
- •Case outcome: interim follow-ups through 12 months
- •Case outcome: interim follow-ups through 12 months (continued)
- •Question
- •Attending physician’s mental notes: 12 month follow-ups
- •Case outcome: interim follow-up, 24 months
- •Attending physician’s mental notes: 36-month follow-ups
- •Case outcome and multiple interim follow-ups to 60 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •A pharmacodynamic moment
- •Antihistamine and the sleep–wake switch
- •Serotonin receptor antagonism and sleep
- •What about 5-ht1d receptor antagonism?
- •What about 5-ht7 receptor antagonism?
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Case outcome: second interim follow-up visit at two months
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Question
- •Case outcome: interim follow-up visits through seven months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through seven months
- •Case outcome: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit eight weeks later
- •Question
- •Case outcome: second and third interim follow-up visits at three months
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through five months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 12 months
- •Attending physician mental notes
- •Case outcome: interim follow-up visits through 15 months
- •Question
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pharmacoeconomic and regulatory moment
- •How many ways can a drug be turned into a slow-release preparation?
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Medication history
- •Psychotherapy history
- •Social and personal history
- •Medical history
- •Family history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four to six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through three months
- •Case outcome: interim follow-up visits through three months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through three months (continued)
- •Case outcome: interim follow-up visits through six months
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Overview
- •Classification
- •Clinical manifestations
- •Therapy and management
- •Posttest self-assessment question and answer
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visit through six months (continued)
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 15 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Neurocircuitry moment
- •Treatments for ocd
- •Posttest-self assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Social and personal history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months (continued)
- •Case outcome: interim follow-up visits through four months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through four months
- •Case outcome: interim follow-up visits through nine months
- •Attending physician’s mental notes: interim follow-up visits through 12 months
- •Case outcome: interim follow-up visits through 18 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Diagnosis
- •Etiology
- •Rls and comorbidity
- •Rls treatment
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months (continued)
- •Case outcome: interim follow-up visits at three months
- •Question
- •Case outcome: interim follow-up visit at four months
- •Attending physician’s mental notes: interim follow-up visits through four months
- •Case outcome: interim follow-up visits through six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pharmacokinetic moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through 12 months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit three months later
- •Question
- •Case outcome: first interim follow-up visit three months later (continued)
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at six months
- •Case outcome: second interim follow-up visit at six months
- •Question
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 36 months
- •Question
- •Case outcome: interim follow-up visits through 48 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits four and eight weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case outcome: interim follow-up visits through nine months
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Question
- •Case outcome: interim follow-up visits through 15 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Neuropsychiatric moment
- •Causes, incidence, and risk factors
- •Symptoms
- •Signs and tests
- •Treatment
- •Prognosis
- •Pharmacodynamic moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Case outcome: interim follow-up visits through five years
- •Question
- •Attending physician’s mental notes: interim follow-up visits through five years
- •Case outcome: interim follow-up visits through six years
- •Question
- •Attending physician’s mental notes: interim visits through year six
- •Case outcome: interim follow-up visits through six years (continued)
- •Question
- •Attending physician’s mental notes: interim visits through year six (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits one to two weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three to four weeks
- •Case outcome: second interim follow-up visit at three to four weeks
- •Question
- •Case outcome: interim follow-up visits through four to six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six weeks
- •Case outcome interim follow-up visits through 10 weeks
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Chronic risks
- •Acute risks predictive of future suicide attempt include*
- •Summary
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Further investigation
- •Case outcome: first interim follow-up visits through six months
- •Question
- •Case outcome: second interim follow-up visits through 12 months
- •Question
- •Case outcome: second interim follow-up visits through 12 months (continued)
- •Question
- •Attending physician’s mental notes: interim visits through 18 months
- •Case outcome: interim follow-up visits through 18 months
- •Question
- •Case outcome: interim follow-up visits through 24 months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 24 months
- •Case outcome: interim follow-up visits through 24 months (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Gaba-a receptors and the positive allosteric modulation of the bZs
- •Gaba-a receptors: desensitization, tachyphylaxis, and tolerance
- •Why does this happen?
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits through three months
- •Question
- •Case outcome: interim follow-up visits through four months
- •Question
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: visits through six months
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Case outcome: interim follow-up visits through nine months (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Case outcome: via telephone
- •Further investigation
- •Case outcome: first interim follow-up six hours later
- •Question
- •Attending physician’s mental notes: six hours later
- •Question
- •Attending physician’s mental notes: interim follow-up information through 72 hours
- •Case outcome: interim follow-up information through 72 hours
- •Case outcome: interim follow-up visits through 80 hours
- •Attending physician’s mental notes: interim follow-up information through 72 hours (continued)
- •Question
- •Case outcome: interim follow-up information through 92 hours
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Delirium primer
- •Posttest self-assessment question and answer
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current psychiatric medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: initial visit
- •Further investigation
- •Question
- •Case outcome: first interim follow-up visit one week later
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Disulfiram (Antabuse)
- •Naltrexone (ReVia)
- •Acamprosate (Campral)
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Social and personal history
- •Medical history
- •Family history
- •Medication history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current psychiatric medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: initial visit
- •Further investigation
- •Case outcome: first interim follow-up visit two months later
- •Question
- •Case outcome: interim follow-up visits three to six months later
- •Attending physician’s mental notes: follow-up visit, six months
- •Case outcome: interim follow-up visits eight to 12 months later
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Medication management of adhd in children versus adults
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Patient evaluation on initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit at six weeks
- •Case debrief
- •Take-home points
- •Patient’s genetic summary
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit at four weeks
- •Case debrief
- •Take-home points
- •A short tutorial on the scientific background of this case
- •Patient’s genetic summary
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit through 16 weeks
- •Case debrief
- •Take-home points
- •Cme online posttest and certificate instructions
- •Index of drug names
- •Index of case studies
Patient evaluation on intake
57-year-old man with a chief complaint of “horrible depression”
Feels he “made a bad decision” late in his career and is now unemployed after many successful years in equipment sales
Fearful and nervous that, at his age, he is too young to retire and too old to find a new job and be successful again
Psychiatric history
He had been without major mental health issues until he left his gainful employment of 25 years as an equipment salesman
– He left during poor corporate economic times assuming his company would fold
– He left for a second company for a sales position in a different market, and performed poorly on commission and was let go
– Psychiatric symptoms developed after this
Has not been able to go back to work at all due to anxiety and fear about failing again
He admits to full syndromal depressive symptoms
– He has passive suicidal thoughts and ideational guilt that he is a bad spouse in that he has let his family down by being unsuccessful and unemployed
– Additionally, he is amotivated, fatigued, and states he is hopeless and pessimistic about the future
He now worries about everything, all the time, cannot focus, and is tense. He states he was never like this before
Additionally, he can barely “look people in the eye” and talk to them
– He is very concerned about doing and saying the right thing
– After years of remembering many details in sales, he can barely keep any facts straight, and is convinced that he will fail
– Panic attacks have occurred at recent job interviews, and since then is avoiding most situations where he has to speak to superiors
He has relatively few friends as most were colleagues at his previous job
While he is at home more, he is experiencing more conflict with his wife, although states she is supportive
Social and personal history
He graduated high school and served successfully in the military without traumatic experience
He was gainfully employed in sales for many years before changing jobs as noted
His wife is employed now but they are having difficulties financially
He does not use drugs or alcohol
Medical history
He has experienced 10 lbs of weight loss while depressed over last several months and is slightly underweight
He has no acute or chronic medical issues
He has no liver or renal disease
Family history
Denies any known psychiatric illness in any family member
Medication history
One treatment so far while in the care of his PCP
– He failed to respond to SSRI, paroxetine (Paxil) 40 mg/d
– Currently, perhaps 10% improvement in intensity and duration of symptoms at most because he feels less sad and weepy, but is still socially not functioning well
Psychotherapy history
Recently, started outpatient CBT with an adept clinician in the local area
Little to no response to these psychotherapeutic interventions, but acknowledges it is early in the course of this intervention and feels comfortable conversing about his problems
Patient evaluation on initial visit
Acute onset of MDD symptoms with associated, or possibly comorbid anxiety disorder roughly six months ago
Suffers immensely with guilt over his decision to leave his successful job for a new job this late in his career
Very compliant with medication management and has started psychotherapy
Good insight into his illness and wants to get better
He has current, fleeting passive suicidal ideation
There is possible guilt-based delusions (current ideation noted) but no other signs of psychosis
Reports no current side effects
