- •Table of Contents
- •Case Studies
- •Volume 2 Stephen m. Stahl
- •Thomas l. Schwartz
- •It furthers the University’s mission by disseminating knowledge in the pursuit of education, learning and research at the highest international levels of excellence.
- •Information on this title: www.Cambridge.Org/9781107607330
- •Illness – Chemotherapy – Examinations, questions, etc. |
- •Isbn 978-1-107-60733-0 Paperback
- •Introduction
- •Learning objectives
- •Accreditation and credit designation statements
- •Optional posttest and cme credit instructions (see p. 441) Peer review
- •Disclosures
- •Authors/developers
- •Disclosure of off-label use
- •Disclaimer
- •Cultural and linguistic competency
- •Provider
- •Support
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Case outcome: second interim follow-up visit at two months
- •Attending physician’s mental notes: interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 12 months
- •Case outcome: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Psychotherapy moment
- •Psychopharmacology components
- •Psychotherapy
- •Documentation
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through six months
- •Question
- •Attending physician’s mental notes: nine months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: nine-month follow-ups
- •Question
- •Attending physician’s mental notes: interim follow-up through nine months (continued)
- •Case outcome and multiple interim follow-ups to 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Tardive dyskinesia
- •Tardive dyskinesia facts
- •Tardive dyskinesia treatments
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through four months
- •Question
- •Attending physician’s mental notes: nine months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: 9–12 month follow-ups
- •Question
- •Case outcome: interim follow-ups through 12 months
- •Case outcome: multiple interim follow-ups through 16 months
- •Attending physician’s mental notes: 16-month follow-ups
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Abnormal Involuntary Movement Scale (aims)
- •Aims instructions
- •Case outcome: use of outcome measures
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Question
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four months
- •Question
- •Case outcome: interim follow-ups through six months
- •Attending physician’s mental notes: interim follow-up, nine months (continued)
- •Case outcome and multiple interim follow-ups to 12–120 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment How does vns theoretically work?
- •Vns side effects
- •Neurostimulation and neuromodulatory devices other than vns
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through one month
- •Question
- •Case outcome: interim follow-ups through two months
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four-month follow-ups
- •Question
- •Case outcome: interim follow-ups through four months (continued)
- •Attending physician’s mental notes: interim follow-ups through four months
- •Case outcome and multiple interim follow-ups to six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Is quetiapine (Seroquel) an antipsychotic, anti-manic, antidepressant, anxiolytic, or a hypnotic?
- •Pharmacodynamics of quetiapine and norquetiapine
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through one month
- •Case outcome: interim follow-ups through two months
- •Attending physician’s mental notes: two months
- •Question
- •Case outcome: interim follow-ups through two months
- •Case outcome: interim follow-ups through three months
- •Question
- •Case outcome and multiple interim follow-ups up to six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Pharmacodynamic moment
- •What is worse in causing escalated mania or mixed features, antidepressants or stimulants?
- •Should unipolar antidepressants be used in bipolar disorder?
- •Does clonazepam (Klonopin) work in bipolar mania?
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Question
- •Case outcome
- •Case debrief
- •Take-home points
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through three months
- •Question
- •Attending physician’s mental notes: four months
- •Case outcome: interim follow-ups through six months
- •Case outcome: interim follow-ups through nine months
- •Question
- •Attending physician’s mental notes: nine-month follow-ups
- •Attending physician’s mental notes: interim follow-up, nine months (continued)
- •Case outcome and multiple interim follow-ups to 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Treating aawg with metformin
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through six months
- •Attending physician’s mental notes: six months
- •Case outcome: interim follow-ups through nine months
- •Case outcome: interim follow-ups through 18 months
- •Attending physician’s mental notes: through 20 months
- •Question
- •Case outcome: interim follow-ups through 24 months
- •Question
- •Attending physician’s mental notes: 24-month follow-ups
- •Case outcome: interim follow-up, 36 months
- •Attending physician’s mental notes: 48-month follow-ups
- •Question
- •Case outcome and multiple interim follow-ups to 48 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Techniques for switching antipsychotics
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Question
- •Case outcome
- •Case debrief
- •Clozapine sialorrhea statistics and etiology
- •Possible antidotes for cis
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Further investigation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim follow-ups through three months
- •Attending physician’s mental notes: six months
- •Case outcome: interim follow-ups through nine months
- •Case outcome: interim follow-ups through 12 months
- •Case outcome: interim follow-ups through 12 months (continued)
- •Question
- •Attending physician’s mental notes: 12 month follow-ups
- •Case outcome: interim follow-up, 24 months
- •Attending physician’s mental notes: 36-month follow-ups
- •Case outcome and multiple interim follow-ups to 60 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •A pharmacodynamic moment
- •Antihistamine and the sleep–wake switch
- •Serotonin receptor antagonism and sleep
- •What about 5-ht1d receptor antagonism?
- •What about 5-ht7 receptor antagonism?
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Case outcome: second interim follow-up visit at two months
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Question
- •Case outcome: interim follow-up visits through seven months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through seven months
- •Case outcome: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit eight weeks later
- •Question
- •Case outcome: second and third interim follow-up visits at three months
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through five months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 12 months
- •Attending physician mental notes
- •Case outcome: interim follow-up visits through 15 months
- •Question
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pharmacoeconomic and regulatory moment
- •How many ways can a drug be turned into a slow-release preparation?
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Medication history
- •Psychotherapy history
- •Social and personal history
- •Medical history
- •Family history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four to six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through three months
- •Case outcome: interim follow-up visits through three months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through three months (continued)
- •Case outcome: interim follow-up visits through six months
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Overview
- •Classification
- •Clinical manifestations
- •Therapy and management
- •Posttest self-assessment question and answer
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visit through six months (continued)
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 15 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Neurocircuitry moment
- •Treatments for ocd
- •Posttest-self assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Social and personal history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months (continued)
- •Case outcome: interim follow-up visits through four months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through four months
- •Case outcome: interim follow-up visits through nine months
- •Attending physician’s mental notes: interim follow-up visits through 12 months
- •Case outcome: interim follow-up visits through 18 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Diagnosis
- •Etiology
- •Rls and comorbidity
- •Rls treatment
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months (continued)
- •Case outcome: interim follow-up visits at three months
- •Question
- •Case outcome: interim follow-up visit at four months
- •Attending physician’s mental notes: interim follow-up visits through four months
- •Case outcome: interim follow-up visits through six months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pharmacokinetic moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through 12 months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 24 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit three months later
- •Question
- •Case outcome: first interim follow-up visit three months later (continued)
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at six months
- •Case outcome: second interim follow-up visit at six months
- •Question
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Case outcome: interim follow-up visits through 36 months
- •Question
- •Case outcome: interim follow-up visits through 48 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Patient evaluation on intake
- •Psychiatric history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits four and eight weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months
- •Case outcome: second interim follow-up visit at three months
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three months (continued)
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six months
- •Case outcome: interim follow-up visits through nine months
- •Attending physician’s mental notes: interim follow-up visits through nine months
- •Question
- •Case outcome: interim follow-up visits through 15 months
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Neuropsychiatric moment
- •Causes, incidence, and risk factors
- •Symptoms
- •Signs and tests
- •Treatment
- •Prognosis
- •Pharmacodynamic moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visit four weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at two months
- •Case outcome: second interim follow-up visit at two months
- •Question
- •Case outcome: interim follow-up visits through five years
- •Question
- •Attending physician’s mental notes: interim follow-up visits through five years
- •Case outcome: interim follow-up visits through six years
- •Question
- •Attending physician’s mental notes: interim visits through year six
- •Case outcome: interim follow-up visits through six years (continued)
- •Question
- •Attending physician’s mental notes: interim visits through year six (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits one to two weeks later
- •Question
- •Attending physician’s mental notes: second interim follow-up visit at three to four weeks
- •Case outcome: second interim follow-up visit at three to four weeks
- •Question
- •Case outcome: interim follow-up visits through four to six weeks later
- •Question
- •Attending physician’s mental notes: interim follow-up visits through six weeks
- •Case outcome interim follow-up visits through 10 weeks
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Chronic risks
- •Acute risks predictive of future suicide attempt include*
- •Summary
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Further investigation
- •Case outcome: first interim follow-up visits through six months
- •Question
- •Case outcome: second interim follow-up visits through 12 months
- •Question
- •Case outcome: second interim follow-up visits through 12 months (continued)
- •Question
- •Attending physician’s mental notes: interim visits through 18 months
- •Case outcome: interim follow-up visits through 18 months
- •Question
- •Case outcome: interim follow-up visits through 24 months
- •Question
- •Attending physician’s mental notes: interim follow-up visits through 24 months
- •Case outcome: interim follow-up visits through 24 months (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Gaba-a receptors and the positive allosteric modulation of the bZs
- •Gaba-a receptors: desensitization, tachyphylaxis, and tolerance
- •Why does this happen?
- •Patient evaluation on intake
- •Psychiatric history
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Further investigation
- •Case outcome: first interim follow-up visits through three months
- •Question
- •Case outcome: interim follow-up visits through four months
- •Question
- •Case outcome: interim follow-up visits through six months
- •Question
- •Attending physician’s mental notes: visits through six months
- •Case outcome: interim follow-up visits through nine months
- •Question
- •Case outcome: interim follow-up visits through nine months (continued)
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Case outcome: via telephone
- •Further investigation
- •Case outcome: first interim follow-up six hours later
- •Question
- •Attending physician’s mental notes: six hours later
- •Question
- •Attending physician’s mental notes: interim follow-up information through 72 hours
- •Case outcome: interim follow-up information through 72 hours
- •Case outcome: interim follow-up visits through 80 hours
- •Attending physician’s mental notes: interim follow-up information through 72 hours (continued)
- •Question
- •Case outcome: interim follow-up information through 92 hours
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Delirium primer
- •Posttest self-assessment question and answer
- •Pretest self-assessment question (answer at the end of the case)
- •Patient evaluation on intake
- •Psychiatric history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current psychiatric medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: initial visit
- •Further investigation
- •Question
- •Case outcome: first interim follow-up visit one week later
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Mechanism of action moment
- •Disulfiram (Antabuse)
- •Naltrexone (ReVia)
- •Acamprosate (Campral)
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Social and personal history
- •Medical history
- •Family history
- •Medication history
- •Psychotherapy history
- •Patient evaluation on initial visit
- •Current psychiatric medications
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: initial visit
- •Further investigation
- •Case outcome: first interim follow-up visit two months later
- •Question
- •Case outcome: interim follow-up visits three to six months later
- •Attending physician’s mental notes: follow-up visit, six months
- •Case outcome: interim follow-up visits eight to 12 months later
- •Case debrief
- •Take-home points
- •Performance in practice: confessions of a psychopharmacologist
- •Tips and pearls
- •Medication management of adhd in children versus adults
- •Posttest self-assessment question and answer
- •Patient evaluation on intake
- •Psychiatric history
- •Patient evaluation on initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit at six weeks
- •Case debrief
- •Take-home points
- •Patient’s genetic summary
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit at four weeks
- •Case debrief
- •Take-home points
- •A short tutorial on the scientific background of this case
- •Patient’s genetic summary
- •Case outcome: initial visit
- •Question
- •Attending physician’s mental notes: initial evaluation (continued)
- •Case outcome: interim visit through 16 weeks
- •Case debrief
- •Take-home points
- •Cme online posttest and certificate instructions
- •Index of drug names
- •Index of case studies
Patient evaluation on intake
26-year-old man with a chief complaint of being “depressed, more or less”
Mainly experiences MDEs of varying lengths and severities, occurring since he was a teenager
Asks for a consultation because he has legal issues concerning an altercation that occurred recently
Psychiatric history
Significant MDEs consistent with recurrent MDD are evident
– Some MDEs have been incapacitating and have interfered with school and work
– Seems to have good inter-episode recovery, which allows him to return to class and work
When in the middle of an MDE, he admits to most MDD symptoms
– Except he does not have suicidal thoughts
– Admits to decreased sleep, despondent thoughts and mood, low interest in activities, poor energy and cognition
– Says his self-esteem drops as he feels disgruntled, rejection-sensitive, and is guilt-ridden for no apparent reason
He admits to SAD symptoms where he
– Is often nervous around new people and acquaintances
– Experiences anticipatory anxiety and will avoid certain social events
– The SAD appears separate from the MDEs where these anxiety symptoms occur regardless of his affective state
The main reason for consultation is that he has a legal issue regarding drinking while driving that he feels was likely fueled by psychiatric symptoms
– At the time of the infraction, he had been started on an SSRI for the MDD and SAD symptoms
This caused his mood to elevate excessively and in a sustained fashion over several days
– With this, he felt invincible and that the law did not apply to him
– During this episode he was also in an altercation at a bar when he purposefully antagonized another patron
This is extremely out of character for his usually quiet, socially anxious demeanor
Despite being a shy, avoidant, SAD person during this period, he lost all anxiety, fear, and avoidance tendencies
– During these spells, he experienced a moderate amount of talkativeness, distractibility, racing thoughts, hyperactivity, hyposomnia, impulsivify (flirting, drinking more than usual, fighting) and grandiosity (becomes invincible, arrogant, back-talking, and challenging of authority [police, bystanders, etc.])
These mood-elevating events were complicated by the fact that AUD criteria were likely met during these times
– While in college, he admitted to heavy alcohol use on weekends
– When depressed, he may use cannabis intermittently
Has now completed college and has few friends in the immediate area
Family is very supportive
Wants to be a writer, specifically a news reporter, and is planning on applying to graduate school
Currently presents in a euthymic state at his first office appointment
Social and personal history
Graduated high school and college
Is not gainfully employed but is considering graduate school now
Drug and alcohol history as noted
He does not smoke and uses low amounts of caffeinated drinks
His family is supportive
Medical history
There are no acute or chronic medical issues
Family history
GAD is reported for his mother
No bipolar family members
Medication history
Via his PCP, he has had two short SSRI trials with sertaline (Zoloft) 50 mg/d and paroxetine (Paxil) 20 mg/d, both of which caused mood elevations with problematic behaviors and drinking
Took a few doses of mood stabilizing divalproex sodium (Depakote) but was too sedated to continue its use
Prescribed the BZ anxiolytic clonazepam (Klonopin) in the past without misuse
Psychotherapy history
None
Patient evaluation on initial visit
Recurring MDD since late teens with comorbid SAD are evident
Possible hypomanic spells in last two to three years versus antidepressant-induced activating side effects versus alcohol intoxication-induced mood disorder
All mood elevations reported seem secondary to SSRI and/or alcohol use
He has not had a chance to be compliant with medication treatment due to side effects
He has no suicidal ideation and no signs of psychosis
He is euthymic now and functioning well psychosocially
