Учебники / Auditory Trauma, Protection, and Repair Fay 2008

Springer Handbook of Auditory Research

Volume 1: The Mammalian Auditory Pathway: Neuroanatomy

Edited by Douglas B. Webster, Arthur N. Popper, and Richard R. Fay

Volume 2: The Mammalian Auditory Pathway: Neurophysiology

Edited by Arthur N. Popper and Richard R. Fay

Volume 3: Human Psychophysics

Edited by William Yost, Arthur N. Popper, and Richard R. Fay

Volume 4: Comparative Hearing: Mammals

Edited by Richard R. Fay and Arthur N. Popper

Volume 5: Hearing by Bats

Edited by Arthur N. Popper and Richard R. Fay

Volume 6: Auditory Computation

Edited by Harold L. Hawkins, Teresa A. McMullen, Arthur N. Popper, and Richard R. Fay

Volume 7: Clinical Aspects of Hearing

Edited by Thomas R. Van De Water, Arthur N. Popper, and Richard R. Fay

Volume 8: The Cochlea

Edited by Peter Dallos, Arthur N. Popper, and Richard R. Fay

Volume 9: Development of the Auditory System

Edited by Edwin W Rubel, Arthur N. Popper, and Richard R. Fay

Volume 10: Comparative Hearing: Insects

Edited by Ronald Hoy, Arthur N. Popper, and Richard R. Fay

Volume 11: Comparative Hearing: Fish and Amphibians

Edited by Richard R. Fay and Arthur N. Popper

Volume 12: Hearing by Whales and Dolphins

Edited by Whitlow W.L. Au, Arthur N. Popper, and Richard R. Fay

Volume 13: Comparative Hearing: Birds and Reptiles

Edited by Robert Dooling, Arthur N. Popper, and Richard R. Fay

Volume 14: Genetics and Auditory Disorders

Edited by Bronya J.B. Keats, Arthur N. Popper, and Richard R. Fay

Volume 15: Integrative Functions in the Mammalian Auditory Pathway

Edited by Donata Oertel, Richard R. Fay, and Arthur N. Popper

Volume 16: Acoustic Communication

Edited by Andrea Simmons, Arthur N. Popper, and Richard R. Fay

Volume 17: Compression: From Cochlea to Cochlear Implants

Edited by Sid P. Bacon, Richard R. Fay, and Arthur N. Popper

Volume 18: Speech Processing in the Auditory System

Edited by Steven Greenberg, William Ainsworth, Arthur N. Popper, and Richard R. Fay

Volume 19: The Vestibular System

Edited by Stephen M. Highstein, Richard R. Fay, and Arthur N. Popper

Volume 20: Cochlear Implants: Auditory Prostheses and Electric Hearing

Edited by Fan-Gang Zeng, Arthur N. Popper, and Richard R. Fay

Volume 21: Electroreception

Edited by Theodore H. Bullock, Carl D. Hopkins, Arthur N. Popper, and Richard R. Fay

Continued after index

Jochen Schacht

Arthur N. Popper

Richard R. Fay

Editors

Auditory Trauma, Protection,

and Repair

123

Library of Congress Control Number: 2007926238

© 2008 Springer Science+Business Media, LLC

All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights.

Cover illustration: This image is Figure 8.2 from the text.

Printed on acid-free paper

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Dedication

This volume is dedicated to Professor Joseph Elmer Hawkins, Jr., scholar, educator, and oto-historian, in recognition of his lifelong contributions to the anatomy and pathology of the auditory system. Every chapter of this book reflects his influence as a scientist and mentor.

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Contents

Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix

Series Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii

Volume Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv

1. Auditory Pathology: When Hearing Is Out of Balance . . . . . . . . . . . . . . . 1

Jochen Schacht

2. Genetics of Hearing Loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

Ella Shalit and Karen B. Avraham

3. Cochlear Homeostasis and Homeostatic Disorders . . . . . . . . . . . . . . . . . . . 49

Philine Wangemann

4. Tinnitus: Theories, Mechanisms, and Treatments . . . . . . . . . . . . . . . . . . . . 101

Carol A. Bauer and Thomas J. Brozoski

5. Autoimmune Inner Ear Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131

Quinton Gopen and Jeffrey P. Harris

6. Age-Related Hearing Loss and Its Cellular and Molecular Bases. . . . . .145

Kevin K. Ohlemiller and Robert D. Frisina

7. Patterns and Mechanisms of Noise-Induced Cochlear Pathology . . . . . . 195

Donald Henderson, Bohua Hu, and Eric Bielefeld

8. Drug-Induced Hearing Loss . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219

Leonard P. Rybak, Andra E. Talaska, and Jochen Schacht

9. Central Consequences of Cochlear Trauma . . . . . . . . . . . . . . . . . . . . . . . . . 257

D. Kent Morest and Steven J. Potashner

10. Cell Death and Cochlear Protection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275

Steven H. Green, Richard A. Altschuler, and Josef M. Miller

11. Emerging Strategies for Restoring the Cochlea . . . . . . . . . . . . . . . . . . . . . . 321

Stefan Heller and Yehoash Raphael

Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .339

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Contributors

richard a. altschuler

Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109-0506, USA, Email: shuler@umich.edu

karen b. avraham

Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978 Israel, Email: karena@ post.tau.ac.il

carol a. bauer

Southern Illinois University School of Medicine, Department of Surgery, Springfield, IL 62794-9662, USA, Email: cbauer@siumed.edu

eric bielefeld

Center for Hearing & Deafness, SUNY at Buffalo, Buffalo, NY 14214, USA, Email: ecb2@buffalo.edu

thomas j. brozoski

Southern Illinois University School of Medicine, Department of Surgery, Springfield, IL 62794-9629, USA, Email: tbrozoski@siumed.edu

robert d. frisina

Otolaryngology Department, University Rochester School of Medicine and Dentistry, Rochester NY, 14642-8629, USA, Email: Robert_Frisina@ urmc.rochester.edu

quinton gopen

Division of Otology and Laryngology, Harvard Medical School, Children’s Hospital Boston, Brigham and Women’s Hospital, Boston, MA 02115, USA, Email: quinton.gopen@childrens.harvard.edu

steven green

Department of Biological Sciences, University of Iowa, Iowa City, IA 522421324, USA, Email: steven-green@uiowa.edu

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