CST 2015 / Protein_Kinase_C
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CELL SIGNALING TECHNOLOGY |
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Protein Kinase C Signaling
Growth Factors,
Insulin, etc.
Receptor
PDK1
Akt/PKB |
PI3K |
p70S6K
PKCζ/λ |
PKCδ |
PKCθ |
PKCµ |
PKCα/βII |
Activated |
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By TPA |
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MARCKs
Pathway Diagram Keys
Kinase |
Enzyme |
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G-protein |
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Direct Inhibitory |
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Tentative Inhibitory |
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Translocation |
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Phosphatase |
pro-apoptotic |
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Acetylase |
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Modification |
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Modification |
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Transcriptional |
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Multistep Stimulatory |
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Separation of Subunits |
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Stimulatory Modification |
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Transcription Factor |
pro-survival |
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Deacetylase |
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Modification |
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or Cleavage Products |
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Transcriptional |
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Caspase |
GAP/GEF |
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Multistep Inhibitory |
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Joining of Subunits |
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Inhibitory Modification |
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Ribosomal subunit |
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Modification |
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Receptor |
GTPase |
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Direct Stimulatory |
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Tentative Stimulatory |
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Modification |
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Modification |
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