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E. Microphages

It is known, that the important component of aero-haematic barrier is surfactant which warns closed alveoli during breathe in. By what cells of alveoli are synthesized phospholipids which constructed these membranes?

A.Alveolocytes ІІ type *

B.Respiratory cells

C.Goblet cells

D.Alveolar macrophages

E.Endotheliocytes of capillaries

In patient with laryngeal diphtheria doctor founded membranous coats on mucosa, that strong connected with epithelia. To what types of epithelia, marked below, the membranous coats fixed strong?

A.Compound keratinazed

B.Compound non-keratinazed *

C.Pseudostatified

D.Simple sqamous

E.Simple cilindrical

In histologic preparation of the organ which wall has mucous, submucous, fibrouscartilage and adventitial shall is submitted. Epithelia - pseudostratified. In submucous

– end-pieces of the mixed glands. Hyaline cartilage forms large plates. What organ has the given morphological attributes?

A.Large bronchi *

B.Trachea

C.Small bronchi

D.Larynx

E.Middle bronchi

In an electronic microphoto of biopsy structures into which structure enters surfactant, alveolocytes I type, basal lamina and fenestrated epithelia of capillaries are submitted. What histo-haematic barrier in human body content from these structures?

A.Haemato-encefalic

B.Haemato-thymic

C.Aero-haematic *

D.Uro-haematic

E.Haemato-testicularis

The patient has acted arrived in branch with attack of asthma which is caused by spasm of smooth muscles of respiratory ways. Name departments of respiratory ways to which basically it is connected this attack.

A.Bronchi of small caliber*

B.Bronchi of middle caliber

C.Bronchi of large caliber

D.Terminal bronchioles

E.Respiratory departments

Lung of premature infant is presented on electronic photomicrography of biopsy material. Collapse of the alveolar wall caused by the deficiency of surfactant was revealed. Disfunction of what cells of the alveolar wall caused it?

A Alveocytes type II *

B Alveocytes type I

CAlveolar macrophages

DSecretory cells

EFibroblasts

A patient was admitted to the hospital with an asphyxia attack provoked by a spasm of smooth muscles of the respiratory tracts. This attack was mainly caused by

51

 

alterations in the following parts of the airways:

 

A Small bronchi *

 

 

B Median bronchi

 

 

C Large bronchi

 

 

D Terminal bronchioles

 

 

E Respiratory part

 

 

At electronic microphotography of pulmonary alveole's wall a big cell presents. Its

 

cytoplasm has a lot of mitochondria, developed Golgi apparatus, osmiophil lamellated

 

corpuscles. What is the main function of this cell?

 

A It produces surfactant

*

 

B It is a component of blood-air barrier

 

C It warms the air

 

 

D It purifies the air

 

 

E It absorbs microorganisms

 

A pathological process in bronchi caused desquamation of epithelium. What cells will

 

regenerate bronchial epithelium?

 

A Basal *

 

 

B Intercalary

 

 

C Ciliate

 

 

D Endocrinal

 

 

E Goblet

 

 

Alveolar space of the acinus was invaded by some bacteria which interacted with the

 

surfactant.This led to the activation of the cells that are localized in the alveolar walls

 

and on the surface. What cells are these?

 

A Alveolar macrophages

*

 

B Alveolocytes type I

 

 

C Endothelial cells

 

 

D Clara cells

 

 

E Alveolocytes type II

 

 

 

32 Urinary system.

Electron micrograph of a kidney fragment presents an afferent arteriole with big

Kidneys. Urinary

cells under endothelium. These cells contain secretory granules. Name this type of

Tract.

cells:

 

 

A Juxtaglomerular*

 

 

B Mesangial

 

 

C Smooth muscular

 

 

D Juxtavascular

 

 

E Interstitial

 

A microphotography represents a fragment of cortical substance of a kidney. This fragment contains thick spot cells and juxtaglomerular cells with big secretory granules. What kidney structure is represented?

AJuxtaglomerular apparatus*

BRenal corpuscle

CFiltering barrier

DProstaglandin apparatus

EChoroid glomus

Electron-microscope investigation of cortical substance of a kidney reveals some structures lined with prismatic epithelium that normally has brush border and deep plicae of plasmolemma in its basal part. There is a big number of mitochondrions between these plicae. These structures belong to the following part of a nephron:

AProximal tubule*

BDistal convoluted tubule

CHenle's loop

DRenal corpuscle

52

E Distal straight tubule

The patient with disease of kidneys which is accompanied by an ischemia of parenchyma has the high level of arterial pressure. What conducting leading factor is the reason of increase the AP at this patient?

A.High level of angiotensin ІІ*

B.High level of vasopressine

C.High level of renine

D.Increase of sympathetic nervous system’s activity

E.Hyperkateholemia

At the patient after a heavy trauma the shock has developed and attributes of acute renal insufficiency (ARI) have appeared. What is conducting leading mechanism of development ARI in this case?

A. Stasis of urine

B. Decreasing of blood pressure*

C.Increasing of blood pressure

D.Renal injury

E.Nephroptosis

Symptoms of anemia are found out in the patient with chronic glomerulonephritis. What has caused occurrence of these symptoms?

A.Decreasing of erithropoietines’ synthesis*

B.Haematuria

C.Increasing of normal erythrocytes’ destruction

D.Haemolysis of erithricytes

E.Decreasing of synthesis of hemoglobin

At the patient of 18 years at laboratory analyses glucose presence in urine is revealed at normal its concentration in blood plasma. The most authentic reason of it is infringement:

A.Glomerular filtration

B.Tubular secretion

C.Glucocorticoids’ secretion

D.Secretion of insulin

E.Tubular reabsorbtion*

At electronic microscopy in renal cortex structures that lining by cylindrical epithelia with brush border and plicaes of basal plasmalemma are defined determined. Between plicaes there are many mitochondrias. What department of nephrons possesses the described structures?

A.Henle’s loop

B.Proximal convoluted tubule*

C.Renal corpuscle

D.Collecting tubule

E.Capsula of nephron

At the girl of 5 years old, who was treated for cystitis, increase temperature up to 390 С is marked. On the basis of clinical and laboratory analyses the acute inflammation of renal pelvises is diagnosed (pyelonephritis). What structural features have most likely caused propensity of child to pyelonephritis?

A.Renal infarct

B.Undevelopment почечных лоханок

C.Short ureters*

D.Renal ectopia

E.Small diameter of ureters

Developmental anomalies of urinary system meet, on the statistical data, in 10-14 % of newborn children. From which sources, marked below, kedney developmented?

53

A.Splanchnotome

B.Mezenchyma

C.Nephrogonotome*

D.Segmental legs

E.Allantois

During clinical inspection in the 35-years woman with disease of kidneys in urine blood cells are found out, that is authentically connected to infringement of renal filter. This filter will consist of what structures?

A.Endotheliocytes, podocytes

B.Three-layered basal lamina

C.Endotheliocytes, basal lamina

D.Podocytes, basal lamina

E.Endotheliocytes, basal lamina, podocytes *

In experiment increase of blood pressure is received from an animal by narrowing of renal arteries. What function of kidneys’ cells causes this effect?

A.Podocytes

B.Juxtaglomerular cells *

C.Endotheliocytes

D.Interstitial cells

E.Cells of macula densa

At the laboratory analysis of urine of the patient it is revealed, that it has subacidic reaction. What cells of kidneys provide this reaction of urine?

A.Cells of collecting tubules *

B.Juxtaglomerular cells

C.Juxtavascular cells

D.Cells of macula densa

E.Interstitial cells

On preparation it is well visible capillary rete, located between two arterioles (rete mirabile). In what body it is possible to find out this picture?

A.In kidney *

B.In liver

C.In suprarenal gland

D.In spleen

E.In lungs

The patient of 46 years has addressed to the surgeon with complaints to allocation from umbilicus a transparent liquid with unpleasant smell. At laboratory research of this liquid it is determined, that it is urine, the diagnosis is established. Surgical treatment is recommended. What structure it is necessary to lead carry out to the given patient?

A.Urahus*

B.Ureter

C.Uretry

D.Umbilical vein

E.Umbilical cord

The low specific gravity of the secondary urine (1002) was found out in the sick person. What is the most distant part of nephron where concentration of secondary urine takes place?

A In the collecting tubules *

BIn the nephron’s glomerulus

CIn proximal tubule of nephron

DIn ascending part of loop of Henle

EIn distal tubule of nephron

54

 

A histological specimen of a kidney shows a part of the distal tubule going between

 

the afferent and efferent arterioles. The cells building the tubule wall have dense

 

nuclei; basal membrane is absent. Such structural formation is called:

 

A Macula densa *

 

B Juxtaglomerular cells

 

C Mesangial cells

 

D Juxtavascular cells

 

E -

 

A histological specimen of kidney shows a structure consisting of a glomerulus of

 

fenestrated capillaries and a bilayer epithelial capsule. Specify this structure:

 

A Renal corpuscle *

 

B Proximal tubule

 

C Distal tubule

 

D Henle's loop

 

E Receiving tube

 

 

33 Male reproductive

In preparation of organ with many tubules which wall is formed by own environment

system. Testis.

which will consist from basal, myoid and fibrous layers is submitted. On basal lamina

 

supporting cells and spermatogenic epithelia placed. What organ is submitted in a

 

preparation?

 

A. Epididimis

 

B. Testis*

 

C. Ductus deferens

 

D. Ejaculatory duct

 

E. Prostata

In an embryo on 2-3 week of development are found out gonocytes - predecessors of reproductive cells. In what material these cells are differentiated?

A.In dermatomes

B.In mesenchyma

C.In germinal ectoderm

D.In yolk sac *

E.In germinal endoderm

At the man of 35 years after the received doze of an irradiation it is broken spermatogenesis. From what cells there is a restoration of spermatogenesis?

A.Glandulocytes

B.Spermatozoa

C.Spermatogonia*

D.Sustentocytes

E.Spermatides

At the middle-aged man occurrence is observed secondary sexual attributes behind female type. What function of testis’ cells is reduced?

A.Sustentocytes

B.Glandulocytes*

C.Spermatozoa

D.Exocrinocytes

E.Fibrocytes

In wall of yolk sac cells with the large nucleus, the raised increased maintenance contents of glycogen and high activity of alkaline phosphotaze are found out. Subsequently these cells with blood on vessels migrate to mesonephros. In what cells of man's reproductive system they are differentiated?

A.Leidig’s cells

B.Supporting cells

C.Spermatogenic cells *

D.Fibroblasts

55

 

 

E. Blood cells

 

 

Activity of man's reproductive system is adjusted by nervous and endocrine systems?

 

 

What from the listed hormones adjust activity of man's reproductive system?

 

 

A. Glycocorticoids

 

 

B. Gonadotrophins

 

 

C. Thyreotroph hormon

 

 

D. Теstosterone*

 

 

E. Epinephrine

 

 

At electronic microscopy coiled seminiferous tubules’ cells of pyramidal shape have

 

 

been found out. In cytoplasm of these cells it is well advanced smooth endoplasmic

 

 

reticulum, Golgy complex and various inclusions. What cells are there?

 

 

A. Spermatogonii

 

 

B. Leidig’s cells

 

 

C. Sustentocytes *

 

 

D. Fibroblasts

 

 

E. Gonocytes

 

 

Attributes of cryptorchism are found out in the boy – undescendence testis in

 

 

scrotum. If not to perform operation, it can result in what consequences?

 

 

A. Death of the supporting cells

 

 

B. Destruction of coiled seminiferous tubules’ wall

 

 

C. Cessation of spermatogenesis*

 

 

D. Migration of testis

 

 

E. Death of the glandulocytes

 

 

At research of prostatic liquid at the patient of 25 years the insufficient quantity

 

 

amount of reproductive cells is revealed. From what cells usually provide sufficient

 

 

quantity amount for fertilisation of spermatozoa?

 

 

A. Spermatogonia *

 

 

B. Sustentocytes

 

 

C. Supporting cells

 

 

D. Leidig’s cells

 

 

E. Glandulocytes

 

 

During pubescence the cells of male sexual glands begin to produce male sex hormon

 

 

testosterone that calls forth secondary sexual characters. What cells of male sexual

 

 

glands produce this hormone?

 

 

A Leidig cells *

 

 

B Sustentocytes

 

 

C Sertoli's cells

 

 

D Supporting cells

 

 

E Spermatozoa

 

 

 

34

Male reproductive

At the patient with a chronic prostatitis unfertilization is observed. What reason of it?

 

tract. Accessories

A. Disturbance of spermatogenesis

 

glands.

B. Unspermatogenesis

 

 

C. Disturbance of hormonal function

 

 

D. Decreasing of mobility of spermatozoa*

 

 

E. Disturbance of immunity system

 

 

 

35

Female

In the ovary specimen colored with hematoxylin-eosin, follicle is determined where

 

reproductive

cubic-shaped follicle epithelium cells are placed in 1-2 layers, and zona pellucida

 

system. Ovaries.

covering is seen around ovocyte. Name this follicle:

 

 

A Primary*

 

 

B Primordial

 

 

C Secondary

 

 

D Mature

56

 

 

E Atretic

 

 

The body of unknown woman has been delivered to medicolegal examination. On

 

 

section in ovary round formation in diameter about 5 sm that contains a pigment of

 

 

yellow color is revealed. This formation will consist of what cells?

 

 

A. Interstitial cells

 

 

B. Myocytes

 

 

C. Follikular cells

 

 

D. Fibroblasts

 

 

E. Luteocytes*

 

 

At preparation of ovary are determined structures which have the big cavity. Оvocyte

 

 

in them it is surrounded with zona pellucida, zona radiata. Wall is formed by layer

 

 

of follicular cells and teka. Specify what structure of ovary has given morphological

 

 

attributes.

 

 

A. Mature follicle *

 

 

B. Premordial follicle

 

 

C. Primary follicle

 

 

D. Yellow body

 

 

E. Atretic body

 

 

In blood of the woman have found out the increased quantity amount of oestrogens.

 

 

What cells synthesize these hormones?

 

 

A. Ovocytes

 

 

B. Follicular cells of secondary follicles *

 

 

C. Follicular cells of primary follicles

 

 

D. Follicular cells of premordial follicles

 

 

E. Follicular cells and ovocytes

 

 

In the woman 50 years old it is found out cyst of ovary. From what structure it has

 

 

developed?

 

 

A. From a follicle *

 

 

B. Ovary cortex

 

 

C. Atretic body

 

 

D. White body

 

 

E. Interstitial cells

 

 

On preparation of ovary many large blood vessels is revealed. What structure of

 

 

ovary on preparation?

 

 

A .Cortex

 

 

B. Medulla *

 

 

C. Thertery follicle

 

 

D. Atretic follicle

 

 

E. Yellow body

 

 

At microscopic research of biopsy of endometrium women who suffers on unfertility,

 

 

are found out changes in its structure, caused by action of progesterone. Where this

 

 

hormone is produced?

 

 

A. In hypothalamus

 

 

B. In follicles

 

 

C. In neurohypophisis

 

 

D. In adinohypophysis

 

 

E. In yellow body *

 

 

 

36

Female

The impact of oxitocine on uterus wall helps to stop uterine bleeding after labor. What

 

reproductive

shall of this oragan react on the effect of this hormone?

 

system. Uterus.

A Myometrium*

 

Mammary gland.

B Endometrium

 

 

C Perimetrium

57

 

D Parametrium

 

E Submucous membrane

 

A patient underwent Caesarean section. During the operation a long incision was made

 

in the uterus wall and the fetus was extracted from uterus. Healing of the sutured

 

myometrium will proceed in the following way:

 

A Formation of a fibrous scar*

 

B Formation of smooth muscular tissue

 

C Formation of cross-striated muscle fibers

 

D Proliferation of myosatellitocytes

 

E Hypertrophy of smooth myocytes

 

After gynecologic operation, the patient of 32 years old began to complain of pain in

 

lower part of abdomen and profuse discharge from vagina. After inspection the

 

diagnosis - an inflammation of an internal shall of uterus is established. What shall

 

have suffered?

 

А. Endometrium*

 

В. Myometrium

 

С. Perimetrium

 

D. Parametrium

 

Е. Peritoneum

 

At biopsy of mammary gland astra-shape cells located between basal lamina and

 

lactocytes are found out. Named a source of development of these cells?

 

A. Myotome

 

B. Sklerotome

 

C. Ectoderm *

 

D. Dermatome

 

E. Endoderm

 

In ovarian-menstrual cycle there are changes in endometrial glands. To what type

 

these glands belong?

 

A. Simple tubular *

 

B. Simple tubulo-alveolar

 

C. Simple alveolar

 

D. Comound alveolar

 

E. Compound tubular

 

 

37 Menstrual cycle.

In a preparation of ovary near to follicles of the different stadies of development

 

appear atretic bodies and mature yellow body. What stage of menstrual cycle is

 

answered with such condition?

 

A. Premenstrual *

 

B. Menstrual

 

C. Postmenstrual

 

D. Regenerative

 

E. Growth of follicle

At the analysis of blood in not pregnant woman the age of 26 years finds out low concentration of oestrogens and high of progesterone. In what stage of ovarianmenstrual cycle the analysis of blood has been made?

A.Premenstrual phase *

B.Menstrual phase

C.Postmenstrual phase

D.Desquamation

E.Proliferation

38Control of mastering of the submodule 4.

58

39Final test control of the module 2.

59