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12

Thymus. Palatine

Medullary substance of a hemopoietic organ's lobule in a histological specimen is

 

Tonsils.

lighter coloured and contains epithelial bodies. What organ are these morphological

 

 

properties typical for?

 

 

A Thymus*

 

 

B Lymph node

 

 

C Spleen

 

 

D Liver

 

 

E Kidney

 

 

At the newborn child it is revealed hypoplasia of thymus. What kind of haemopoiesis

 

 

will be broken?

 

 

A. Lymphopoiesis*

 

 

B. Neutrophilopoiesis

 

 

C. Erythropoiesis

 

 

D. Monocytopoiesis

 

 

E. Megakariocytopoiesis

 

 

On histological preparation the organ wich consists of lobules that are surrounded by

 

 

layers of connective tissue. At the periphery of lobules the number of cells is more

 

 

than in the center, lymph nodules are absent. Which organ is represented?

 

 

A Thymus*

 

 

B Red bone marrow

 

 

C Lymph node

 

 

D Spleen

 

 

E Tonsils

 

 

The antigen independent proliferation and differentiation of T lymphocytes are studied

 

 

in the child with impaired immune reactivity. Punctate of what organ was taken for

 

 

study?

 

 

A Thymus*.

 

 

B Spleen.

 

 

C Lymph nodes.

 

 

D Red bone marrow.

 

 

E Tonsils

 

 

Histological examination of a 40 y.o. man's thymus revealed decreased share of

 

 

parenchymatous elements, increased share of adipose and loose connective tissue,

 

 

and its enrichment with thymus bodies. The organ's mass was unchanged. What

 

 

phenomenon is it?

 

 

A Age involution*

 

 

B Accidental involution

 

 

C Hypotrophy

 

 

D Dystrophy

 

 

E Atrophy

 

 

The specimens present sections of haemopoetic and immunogenetic organs. Organ

 

 

has lymph tissue forming different structures (lymph nodes, lobules, bars). In what

 

 

organ does antigen-independent proliferation and differantiation take place?

 

 

A Thymus*

 

 

B Lymphatic nodes

 

 

C Spleen

 

 

D Hemolymph nodes

 

 

E Tonsil

 

 

 

13

Spleen. Lymph

Examination of a patient who was exposed to the X-ray radiation revealed damage of

 

nodes.

wight pulp of the spieen. What cells of white pulp undergo pathological changes?

 

 

A Lymphocytes*

 

 

B Neutrophilic leukocytes

 

 

C Basophilic leukocytes

31

DMonocytes

ETissue basophils

At morphological research of a spleen activization of immunity reactions in an organism has been determined. In what structures of the given organ begins secondary proliferation of T-lymphocytes?

A. Mantile zone of white pulp B. Red pulp

C.Periarterial zone of white pulp*

D.Marginal zone of white pulp

E.Central zone of white pulp

On preparation the organ is submitted, in reticular stroma which matures cells of blood and lymph nodules are placed. What organ is submitted on preparation?

A.Tonsils

B.Тhymus

C.Spleen *

D.Lymph node

E.Red bone marrow

At the preparation the organ is represented wich covered connective tissue capsule from which trabeculae away. In the organ you can distinguish cortex, which contains lymphatic nodules, and the medulla with lymphoid cells. Which organ is represented on the preparation?

ALymph node*

BThymus

CSpleen

DRed bone marrow

ETonsils

At histological preparation the organ’s parenchyma is represented by lymphoid tissue that forms the lymph nodules, the latter are diffusely and contain a central artery. Which organ is represented on the preparation?

ASpleen*

BTonsils

CLymph node

DThymus

ERed bone marrow

At histological preparation there is an organs which cells form three types of lymphatic structure: lymphatic nodules, sinuses and medullary cord. Which organ is represented?

ALymph node*

BSpleen

CThymus

DTonsils

ERed bone marrow

The spherical formations of lymphocytes were found on micropreparations. In the middle of formations - the central artery. Which organ is examined?

A Spleen. *

BKidney.

CThymus.

DBone marrow.

ELymph node.

A student examinated two histological preparations. Both of them had organs that had lymph nodules. On the first preparation - only follicles, and on the secondfollicles contained eccentrically vessel. Determine what kind of organ?

32

 

A First - lymph node, the second - spleen*

 

B The firstred bone marrow, the second-spleen

 

C The first - thymus, the second - spleen

 

D The first -liver, the second-lymph node

 

E The first - liver, the second-spleen

 

In a histological specimen parenchyma of an organ is represented by lymphoid tissue

 

that forms lymph nodes; the latter are arranged in a diffuse manner and enclose a

 

central artery. What anatomic formation has such morphological structure?

 

A Spleen *

 

B Tonsil

 

C Lymph node

 

D Thymus

 

E Red bone marrow

 

A specimen shows an organ covered with the connective tissue capsule with trabeculae

 

radiating inward the organ. There is also cortex containing some lymph nodules, and

 

medullary cords made of lymphoid cells. What organ is under study?

 

A Lymph node *

 

B Thymus

 

C Spleen

 

D Red bone marrow

 

E Tonsils

 

 

14 System of the

A patient has a skin defect as a result of an extensive burn. In order to mask this defect

immunity

the surgeons transplanted a skin flap from other body part of this patient. What

defence.

type of transplantation is it?

 

A Autotransplantation*

 

B Explantation

 

C Allotransplantation

 

D Xenotransplantation

 

E Homotransplantation

Blood analysis of a 16-year-old girl suffering from the autoimmune inflammation of thyroid gland revealed multiple plasmatic cells. Such increase in plasmocyte number is caused by proliferation and differentiation of the following blood cells:

AB-lymphocytes*

BT-helpers

CTissue basophils

DT-killers

ET-supressors

At older people’s frequency of occurrence of tumors rises. One of principal causes of it:

A.Decreasing of intensity of antibodies’ formation

B.Increasing of frequency of infringements mitosis

C.Decreasing of activity of cellular immunity*

D.Increasing of activity of cellular immunity

E.Increasing of activity of antibodies’ formation

To the patient with the big burns have made change of a donor’s skin. But for 8 day transplantant’s color has changed and for 11 day it started to be torn away. What cells accepted in it participation?

А. T-lymphocytes*

B. Erythrocytes С. B-lymphocytes

D.Acidophills

E.Basophills

33

 

 

A patient 30 years was diagnosed with skin tumor. What epidermal cells take part in

 

 

the immune response?

 

 

A T-lymphocytes*

 

 

B Keratinocytes

 

 

C Keratinocytes and Merkel cells

 

 

D Merkel cells

 

 

E Cells of stratum spinosum

 

 

Burn wound was closed pig skin (heterotransplantation). Name the effector cells with

 

 

reject the transplant (pig skin).

 

 

A T-killer*

 

 

B T-helper

 

 

C T-suppressor

 

 

D B lymphocytes

 

 

E Natural killer

 

 

Antibodies are produced when antigen enters the body repeatedly. With the

 

 

function of what immune cells this phenomenon linked?

 

 

A Memory lymphocytes*

 

 

B T - killer

 

 

C T - suppressor

 

 

D Macrophages

 

 

E Dendritic cells

 

 

In girl’s blood 16 years old which suffers autoimmune inflammation of thyroid

 

 

gland, numerous plasma cells are found out. With proliferation and differentiation of

 

 

what blood cells connects increase in quantity amount plasma cells?

 

 

A. T-lymphocytes

 

 

B. T-helpers

 

 

C. Mast cells

 

 

D. Т-killers

 

 

E. B-lymphocytes *

 

 

 

15

Endocrine system.

A 35 year old patient complains about permanent thirst, poor appetite. He drinks 9 l

 

Hypothalamus.

water per day. Daily diuresis is increased, urine is colourless, and its relative

 

Epiphysis.

density is 1,005. The most probable cause of this pathology development is damege

 

 

of:

 

 

A Hypothalamic nuclei*

 

 

B Epithelium of renal tubuli

 

 

C Adenohypophysis

 

 

D Epiphysis

 

 

E Basal membrane of glomerular capillaries

 

 

Woman 40 years old have powerless childbirth, caused by weakness of contractile

 

 

abilities of myometrium. What hormonal preparation needs to be entered to help her?

 

 

A. Аldosterone

 

 

B. Cortisol

 

 

C. Dexamethasone

 

 

D. Оxitocine *

 

 

E. Prednisolone

 

 

 

16

Hypophysis.

The aim of the morphological study was to investigate an endocrine gland with

 

Hypothalamo-

parenchyma consisting of epithelium and neural tissue. In the epithelial trabeculae

 

hypophyseal

the study revealed two types of cells: chromophile and chromophobe. Identify this

 

system.

organ:

 

 

A Pituitary gland*

 

 

B Adrenal gland

 

 

C Hypothalamus

 

 

D Thyroid gland

34

E Parathyroid gland

The patient of very high growth comes to the doctor. He has long thick fingers of hands, the big bottom jaw and the drooped lower lip. Increased secretion of what hormone can be suspected?

A. Somatotrophin*

B. Thyrotroph

C.Gonadotroph

D.Vasopressin

E.Oxitocin

Growth of the child of 10 years reaches achieves 178 sm, weight - 64 kg. What endocrine gland it is connected to infringement of activity?

A.Reproductive

B.Suprarenal

C.Thyroid

D. Hypophysis*

E. Parathyroid

 

A month later after childbirth the woman of 25 years addressed to the doctor with

 

complaints to decrease reduction in quantity amount of milk. What reduction of

 

secretion of hormone has led to such condition?

 

A. Thyrotrophin

 

B. Insuline

 

C. Prolactine*

 

D. Gonadotrophin

 

E. Somatotrophin

 

Student investigated endocrine gland. Its parenchyma consists of epithelium and

 

neural tissue. Epithelial trabecules have two types of cells: chromophilic and

 

chromophobic. Identify this organ:

 

A Hypophysis *

 

B Adrenal glands

 

C Hypothalamus

 

D Thyroid gland

 

E Parathyroid gland

 

 

17 Thyroid gland.

A 9 y.o. boy was admitted to the endocrinological department. This boy has already

Parathyroid

had several fractures of his extremities due to bone brittleness. The function of the

glands.

following endocrinal glands (gland) is disturbed:

 

A Parathyroid*

 

B Thyroid

 

C Thymus

 

D Adrenal

 

E Epiphysis

Parodontitis is treated with calcium preparations and hormones that stimulate tooth mineralization and inhibits tissue resorption. What hormone is it?

ACalcitonin*

BParathormone

CAdrenalin

DAldosterone

EThyroxine

Clinical examination of a female patient revealed reduction of basal metabolism by 40%, gain in body mass, drop of body temperature, face puffiness, sexual disfunctions, inertness and apathy, lowered intelligence. These symptoms are caused by dysfunction of the following endocrine gland:

A Hypofunction of thyroid gland*

35

BHypofunction of parathyroid glands

CHypophysis hyperfunction

DEpiphysis hypofunction

EHyperfunction of thyroid gland

After a surgical procedure an experimental animal died from intense convulsions. What endocrinal glands were extracted?

AParathyroid*

BThyroid

CAdrenal

DOvaries

ETesticles

A 5-month-old boy was hospitalized for tonic convulsions. He has a life-time history of this disease. Examination revealed coarse hair, thinned and fragile nails, pale and dry skin. In blood: calcium - 1,5 millimole/l, phosphor - 1,9 millimole/l. These changes are associated with:

AHypoparathyroidism*

BHyperparathyroidism

CHyperaldosteronism

DHypoaldosteronism

EHypothyroidism

The woman of 53 years, growth of 163 sm, weight of 93 kg, fat constitution, the face with edema, inactive, apathetic. Infringement of functions what endocrine gland causes a condition of the patient?

A. Suprarenal B. Gonades C. Parathyroid

D.Thyroid*

E.Hypophysis

On histopreparation it is submitted parenchymal organ. Parenchyma consists of the many follicles which wall is formed by a layer of cuboidal cells. In a gleam of follicles collects colloid. To what organ such morphological attributes are characteristic?

A.Thyroid gland*

B.Ovaries

C.Lymph node

D.Hypophysis

E.Suprarenal gland

At the patient for the third day after total thyroidectomia muscle spasmes have appeared. What medical products should be appointed this patient?

A.Preparates of calcium*

B.Antispasmatic drags

C.Sedative drags

D.Antibiotics

E.Preparates of potassium

Kidneys of a man under examination show increased resorbtion of calcium ions and decreased resorbtion of phosphate ions. What hormone causes this phenomenon?

A Parathormone *

BThyrocalcitonin

CHormonal form D 3

DAldosterone

EVasopressin

18

Suprarenal gland. In a histological specimen of adrenal cortex there are petite polygonal cells that form

36

roundish clusters and contain some lipidic inclusions. What part of adrenal is presented in this histological specimen?

AGlomerular zone*

BIntermedial zone

CFasciolar zone

DReticular zone

E-

A patient ill with adenoma of glomerular zone of adrenal cortex (Conn's disease) has arterial hypertension, convulsions, and polyuria. What is the main factor in the pathogenesis of these disturbances?

AAldosterone hypersecretion*

BAldosterone hyposecretion

CCatecholamines hypersecretion

DGlycocorticoids hypersecretion

EGlycocorticoids hyposecretion

Microscopic examination of a parenchymatous organ revealed that its epithelial cords formed glomerular, fascicular and reticular zones. The central part of the organ was presented by accumulations of chromaffin cells. Specify this organ:

AAdrenal gland*

BThyroid gland

CEpiphysis

DLiver

EHypophysis

A patient with Itsenko-Cushing syndrome has persistent hyperglycemia and glycosuria, hypertension, osteoporosis, obesity. Increased synthesis and hypersecretion of the following hormone will be observed in this case:

ACortisol*

BAdrenaline

CGlucagon

DThyroxin

EAldosterone

At the man of 42 years which long time was in a condition of stress, in urine the contents of 17-ketosteroids is considerably increased, that first of all testifies to increase of secretion:

A.Epinephrine *

B.Estradiol

C.Kortizol

D.Norepinephrine

E.Aldosterone

Organ’s parenchyma forms dense glomerulus, formed from endocrinocytes. To what organ the given structure is characteristic?

A.Lymph node

B.Spleen

C.Kidney

D.Suprarenal gland*

E.Pancreas

A patient has been given high doses of hydrocortisone for a long time. This caused atrophy of one of the adrenal cortex zones. Which zone is it?

A Fascial *

BGlomerular

CReticular

DGlomerular and reticular

E-

37

19

Control

 

of

 

 

mastering

of

the

 

 

submodule 3.

 

 

20

General

 

 

In course of embryogenesis maxillary and mandibular processes grow together

 

description

of

with a delay. What development anomalies should be expected in this case?

 

organs

of

the

A Macrostomia*

 

digestive

system.

B Microstomia

 

Development

of

C Cleft palate

 

face and organs of

D Gothic palate

 

oral cavity

 

E Cleft of superior lip

 

The constant nasal regurgitation of milk from a nose has been detected at

 

newborn during the first feeding. What anomaly of development does this

 

symptom testify to?

 

A. Bronhiogenic fistula

 

B. Makrostomija

 

C. Mikrostomija

 

D. Hiatus of palate*

 

E. Hiatus of lips

 

At the baby during the certificate acts of swallowing nasal regurgitation of milk

 

from a nose. At survey of the child the surgeon has found out congenital defect, so-

 

called “the wolf mouth”. Specify what anomalies of development result in occurrence

 

of the given pathology.

 

A. Defect between mandibular processes

 

B. Infringement of accretion of average of nasal and maxillar processes

 

C. Defect between palatal processes *

 

D. Defect between lateral lingual tuberculums

 

E. Infringement of development of the frontal processes

 

At the newborn child defect of formation of the human - a medial crevice of the

 

upper lip is determined. What infringement of growth of human’s a germ has taken

 

place in this case?

 

A. Medial nasal processes*

 

B. Lateral nasal and maxillar processes

 

C. Maxillar and mandibular processes

 

D. Palatal processes

 

E. Lateral lingual swellings

 

 

21 Description of the

The stomatologist in cabinet study has given the task to the intern to survey at the

oral mucosa. Lip.

patient sites of oral mucousa, which keratinazed. What it is a site?

Cheek. Gums.

A. Ventral surface of the tongue and palatine tonsils

 

B. Hard palate, ventral surface of the tongue, gingiva

 

C. Cheeks, lower lip, tongue

 

D. Palate and a diaphragm of the mouth

 

E. Hard palate, marginal zone of gingiva and intermediate part of cheeks *

The student has remembered, that epithelia of oral mucosa non-keratinazed. On a histological preparation of the cheek he has seen, that from both its parties sides keratinized epithelia. What the student should remember?

A.Mandibular zone of a cheek can keratinized

B.Maxillar zone of a cheek can keratinized

C.Intermediate zone of a cheek can keratinized*

D.Place of parotid duct opened can keratinized

E.Marginal zone of a cheek can keratinized

On a histological preparation oral cavity’s organ which will consist of three parts, - skin, intermediate and mucous is seen. The basis is formed striated muscle tissue.

38

 

 

What it for body?

 

 

A. Cheek

 

 

B. Gingiva

 

 

C. Hard palate

 

 

D. Soft palate

 

 

E. Lip*

22 Development

and

A histological specimen of an oral cavity organ demonstrates that the organ's anterior

structure

of

surface is lined with squamous nonkeratinized epithelium, and its posterior surface -

tongue. Hard

and

with pseudostratified ciliated epithelium. What organ is it?

soft palate

 

A Soft palate*

 

 

B Gingiva

 

 

C Hard palate

 

 

D Lip

 

 

E Cheek

A child damaged the lateral surface of his tongue. What lingual papillas are most likely to be damged?

AFoliate*

BConic

CVallate

DFiliform

EFungiform

There is a specimen of soft palate where both oral and nasal surfaces can be seen. It was revealed that oral cavity had damaged epithelium. What epithelium is damaged?

AStratified squamous nonrtratinized*

BStratified cuboidal nonrtratinized

CStratified cilindrical nonrtratinized

DStratified squamous keratinized

EPseudostratified ciliated epithelium

On a histological preparation of oral cavity’s organ it is visible 4 zones: adipouse, glandular, sutural and marginal. What for organ on a preparation?

A.Soft palate

B.Gingiva

C.Hard palate *

D.Lip

E.Cheek

On a histological preparation of oral cavity’s organ it is visible, that the one surface is covered by non-keratinized epithelia, and the second surface – pseudostratified epithelia. What it for body?

A.Cheek

B.Gingiva

C.Hard palate

D.Soft palate *

E.Lip

At the sick child the white strike in tongue is observed. Due to what papilla there is a given phenomenon?

A.Circumvallate

B.Foliate

C.Conic

D.Fungiform E. Filiform *

As a result of the chemical burn of the lateral surface of tongue at 5 years child in this site there is no taste sensitivity that is connected to destruction of taste touch cells. What structures of the cell take part in perception recognition of taste?

39

A.Microvilli on apical surfaces *

B.Lateral surface

C.Microvilli on basal surfaces

D.Nucleus

E.Basal lamina

23Large and small At micropreparation of the submandibular salivary gland there are shown some salivary glands basket-shaped cells concentrated around the acini and excretory ducts. These cells surround bases of the serous cells and are called myoepitheliocytes. These cells relate

to the following tissue: A Muscle tissue *

B Epithelial tissue C Nervous tissue

D Special connective tissue

E Loose fibrous connective tissue

A histological specimen of a mandibular gland shows an exctretory duct. Mucous membrane of the duct is lined with cuboid epithelium whose cells have weakly developed organellas. What excretory duct is it?

AIntercalated*

BStriated

CInterlobular

DCommon excretory

E-

A microspecimen of parotid gland presents secretory acini with serous cells that synthesize mostly enzymes. According to the chemical composition classification, the parotid gland relates to the following glands:

ASerous*

BMucous

CSeromucous

DEnzymatic

E-

Examination of a microspecimen made of an unknown organ revealed some acini that contained 10-15 cone cells with basophilic cytoplasm, round nucleus and well developed granular endoplasmic reticulum. An acinus is surrounded by a basal membrane with myoepithelial cells localized in its splitting. What organ is the slice made of?

AParotid gland*

BPancreas

CLungs

DSublingual gland

ELiver

At an acute inflammation of parotid gland processes of secretion and allocation are broken. What cells suffer thus?

A.Serous, mucous

B.Albuminous, serous, mucous

C.Serous, cells with basal striation, stellate cells

D. Serous, myoepithelial cells *

E. Bordered epitheliocytes, cells with basal striation

At chronic inflammatory processes of salivary glands damage of ductal epithelia is observed. What epithelia will be damaged injured thus in striated ducts of major salivary glands?

A.Cuboidal epithelia with basal striation

B.Cilindrical epithelia with basal striation *

40