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CLymphocytes

DMonocytes

EBasophilic leukocytes

In smear of peripheral blood among leukocytes prevalate spherical cells with the segmented nucleus. Fine granularity in their cytoplasm colorated in blue and red colours. How these cells refer to?

A.Young neutrophills

B.Basophills

C.Acidophills

D.Segment-shape-nucleus neutrophills *

E.Моnocytes

At the analysis of blood the reduced maintenance hemoglobin’s contents is revealed. What function of blood will be disturbed thus?

A.Transport of hormones

B.Transport of gases *

C.Maintenance of immunity

D.Blood regeneration

E.Transport of nutrients

Inflammation is characterized by reaction of blood capillaries on a site of damage, reduction of blood circulation, increase of permeability of the vessels’ wall. To what cells, mentioned below, possesses a leaguing role in it?

A.To macrophages

B.To fibroblasts

C.To plasma cells

D.To acidophills

E.To basophills*

In the analysis laboratory assistant has the additional conclusion that the blood belongs to the women. Features of the structure of what formed elements allow making a conclusion?

A Neutrophilic leukocytes*

BErythrocytes

CLymphocytes

DMonocytes

EBasophilic leukocytes

At histochemical research of leukocyte in blood smear there were found cells in which contain granules with histamine and heparin. What are cells?

ABasophils*.

BNeutrophils.

CEosinophils.

DMonocytes.

EErythrocytes

At transplantation of organ there was detected transplant rejection. Which blood cells provide this process?

A T – killer *

BT-helper

CT-suppressor

DT-lymphocytes-O

ET-lymphocytes-memory

Large cells with basophilic cytoplasm and bean-shaped nucleus is seen in a blood smear. The cell is the largest among the visible cell in the field of view. What is a cell?

A Monocytes*

11

 

 

B Macrophage

 

 

C Plasmocyte

 

 

D Basophils

 

 

E Small lymphocyte

 

 

In the experiment B lymphocytes were market in blood. Foreign protein was entered

 

 

the animal under the skin. What cells in the connective tissue will contain this mark?

 

 

A Plasma cells *

 

 

B T lymphocytes

 

 

C Macrophages

 

 

D Basophils

 

 

E Fibroblasts

 

 

Numerous plasma cells were found in the blood girl 16 years old, suffering from an

 

 

autoimmune inflammation of the thyroid gland. With the proliferation and

 

 

differentiation of what blood cells cause increase of plasmocyte?

 

 

A B lymphocytes*

 

 

B T-helper

 

 

C Mast cells

 

 

D T-killer

 

 

E T-suppressor

 

 

A student is given two smears preparations. One - the whole field of view covered by

 

 

erythrocytes, the second - defined blood cells in varying degrees of maturity. What

 

 

kind of smear?

 

 

A Blood and red bone marrow *

 

 

B Blood and lymph

 

 

C Blood frogs and human blood

 

 

D Blood smear and yellow bone marrow

 

 

E Smear of yellow and red bone marrow

 

 

At research of the patient's blood smear there were found the cells wich make up the

 

 

0.5% of total leukocytes and have S-shaped nucleus and blue granules in the

 

 

cytoplasm. What are these cells?

 

 

A Basophils*

 

 

B Neutrophils

 

 

C Eosinophils

 

 

D Monocytes

 

 

E Lymphocytes

 

 

Live vaccine is injected into the human body. Increasing activity of what cells of

 

 

connective tissue can be expected?

 

 

A Plasma cells and lymphocytes*

 

 

B Macrophages and fibroblasts

 

 

C Pigmentocytes and pericytes

 

 

D Adipocytes and adventitious cells

 

 

E Fibroblasts and labrocytes

 

 

In the blood of a 26-year-old man it was revealed 18% of erythrocytes of the

 

 

spherical, ball-shaped, flat and thorn-like shape. Other erythrocytes were in the

 

 

form of the concavo-concave disks. How is such phenomenon called?

 

 

A Physiological anisocytosis

 

 

B Pathological poikilocytosis

 

 

C Physiological poikilocytosis *

 

 

D Pathological anisocytosis

 

 

E Erytrocytosis

 

 

 

12

Myeloid and

In myeloid tissue punctate child 6 years cells are found. In these cells there were

 

lymphoid tissues

remove the nucleus during the process of differentiation. What kind of

12

 

of haemopoiesis.

hematopoiesis, characterized by morphological changes in the data.

 

Myelopoiesis and

A Erythrocytopoiesis *

 

lymphopoiesis.

B Trombotcytopoiesis.

 

 

C Granulcytopoiesis

 

 

D Lymphocytopoiesis

 

 

E Monocytopoiesis

 

 

At histological examination of biopsies of red bone marrow there were found the

 

 

cells of granulocytic group. What changes take place in the nucleus during

 

 

differentiation of these cells?

 

 

A Segmentation*

 

 

B Poliploidiya

 

 

C Piknoz

 

 

D Enucleation

 

 

E Increasing the size

 

 

At electron micrographs of red bone marrow ther were the megakaryocytes wich have

 

 

demarcation channels in the peripheral part of the cytoplasm. What is the role of

 

 

these structures?

 

 

A Formation of platelets *

 

 

B Increasing the surface area of the cells.

 

 

C Increase the number of ion channels.

 

 

D Division cell

 

 

E Destruction of cells

 

 

In punctate of red bone marrow ther were found a significant decrease in the number

 

 

of megakaryocytes. What changes in peripheral blood is accompanied?

 

 

A Decrease the number of platelets*

 

 

B Increasing the number of lymphocytes

 

 

C Increase the number of platelets

 

 

D Decrease the number of lymphocytes

 

 

E Decrease the number of monocytes

 

 

During postembryonal haemopoiesis in the red bone marrow the cells of one of the

 

 

cellular differons demonstrate a gradual decrease in cytoplasmic basophilia as well as

 

 

an increase in oxyphilia, the nucleus is being forced out. Such morphological

 

 

changes are typical for the following haemopoiesis type:

 

 

A Erythropoiesis *

 

 

B Lymphopoiesis

 

 

C Neutrophil cytopoiesis

 

 

D Eosinophil cytopoiesis

 

 

E Basophil cytopoiesis

 

 

 

13 Fibrous

A specimen of connective tissue of derma was stained with Sudan III and

 

connective

hematoxylin. There are clusters of big polygonal cells that turned orange. Their nuclei

 

tissues.

are flattened and located on periphery. What tissue is it?

 

 

A White adipose*

 

 

B Brown adipose

 

 

C Reticular connective

 

 

D Hyaline cartilaginous

 

 

E Lamellar osseous

To the cosmetician the patient with the request has addressed to deprive his tattoo on a shoulder. What substance which contains in a connective tissue, limits distribution of dye and makes possible such kind of "painting"?

A.Geparin

B.Fibronektin

C.Gamma-globulin

D.Elastin

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E. Hyaluronic acid*

At healing a wound in a site of defect of tissue develops scar from connective tissue. What cells provide this process?

A.Fibrocytes

B.Маcrophages

C.Fibroblasts*

D.Lymphocytes

E.Меlanocytes

On the histologic section of areolar connective tissue rather big cells filled basophilic granularity are found; with histochemical methods it is established, that granules contain heparine and histamine. What’s type of cells?

A.Аdipocytes

B.Fibroblasts

C.Маcrophages

D.Plasma cells

E.Mast cells*

As a result of contact on manufacture with Cr-connections at the woman has arisen allergic dermatitis of both hands. What cells of the skin have mainly taken part in realization of this disease?

A.Mast cells*

B.Plasma cells

C.Маcrophages

D.Neutrophills

E.Lymphocytes

The esophageal constriction occurred after a chemical burn due to its local scar formation. What cells of loose connective tissue involved in the formation of scars?

AMature specialized fibroblasts*

BYoung fibroblasts

CFibrocyte

DMyofibroblasts

EFibroclast

As a result of thrombosis of the left coronary artery the groups of contractile cardiomyocytes were damaged. What type of cells will take part in reparative regeneration in the area of damage?

AFibroblasts*

BCardiomyocytes

CMiosymplast

DMiosateliocyte

ESmooth myocytes

In the experiment B lymphocytes were labeled. The animal was injected subcutaneous a foreign protein. What cells of the connective tissue will contain this label?

APlasmocyte *

BT lymphocytes

CMacrophages

DBasophils

EFibroblasts

During the training an athlete was injured lower extremity. Traumatologist diagnoses the rupture of tendon. What type of connective tissue does tendon belongs?

ADense regular connective tissue*

BDense irregular connective tissue

CLoose connective tissue

DReticular tissue

14

 

E Cartilage

 

With age, the human skin is changed, its elasticity decreases. What elements of

 

connective tissue provide its elasticity?

 

A Collagen and elastic fibers*

 

B Ground substance

 

C cells of the epidermis

 

D cells of connective tissue

 

E Reticular fibers

 

A lot of stem cells of red bone marrow were destroyed in the experiment.

 

Development of what populations of cells in the loose connective tissue is inhibited?

 

A Macrophages*

 

B Fibroblasts

 

C Pigment cells

 

D Lipocyte

 

E Pericytes

 

Decreased blood supply to the organs causes hypoxia that activates fibroblasts

 

function. Volume of what elements is increased in this case?

 

A Intercellular substance *

 

B Vessels of microcircular stream

 

C Nerve elements

 

D Parenchymatous elements of the organ

 

E Lymphatic vessels

 

 

14 Development and

During the experimental analysis of chondrohistogenesis a sclerotome was damaged.

structure of

What cells will it make impossible to differentiate?

cartilage tissue

A Chondroblasts*

 

B Smooth myocytes

 

C Myoblasts

 

D Fibroblasts

 

E Epidermocytes

As a result of a chest trauma the costal cartilage was damaged. The cartilage regenerated due to the following layer of perichondrium:

AChondrogenic*

BFibrous

CElastic

DCollagen

ESharpey's fibers

At electronomicroscopic research of the hyaline cartilage’s cells with well advanced rough endoplasmic reticulum, Golgy complex come to light. What function is carried out with these cells?

A. Secretion of the lipids

B. Desruction of intercellular substance of a cartilage

C.Keeping of the glycogen

D.Formation of intercellular substance*

E.Nutrition of the cartilage tissue

On histological preparation of cartilage are isogenic group of cells. What are the initial cells in the formation of these groups?

AChondrocytes I type *

BChondroblasts.

CPrechondroblasts.

DChondrocytes type II.

EChondrocytes type III

15

 

Articular cartilages don’t have perichondrium. What type of these cartilages’ growth

 

are in the process of regeneration?

 

A Interstitial*

 

B Appositional

 

C By imposing

 

D Appositional and interstitial

 

E Does not react

 

 

15 Structure of bone

The symptoms of regeneration process (callus) on the place of fracture were

tissues.

revealed in the histologic specimen of tubular bone. What tissue forms this structure?

 

A Fibrous bone tissue*

 

B Loose connective tissue

 

C Reticular tissue

 

D Epithelial tissue

 

E Lamellar bone tissue

A histological specimen presents the tissue that contains cells having no processes and a few tens of nuclei each. One of cell surfaces has a corrugated zone that provides secretion of hydrolytic elements. What tissue is it?

ABone tissue*

BCartilage tissue

CEpithelial tissue

DNerve tissue

EMuscle tissue

Calcification of the intercellular substance of bone tissue is accompanied by the deposition of hydroxyapatite crystals along the collagen fibers. This process requires the presence of alkaline phosphatase in the intercellular substance. What cell produces this enzyme?

AOsteoblast*

BOsteocyte

COsteoclast

DChondroblast

EChondrocyte

The resorbtion (destruction) of bones is found in the patient. To what hyperactivity of bone cells it is connected?

A.Оsteocytes

B.Оsteoblasts and osteoclasts

C.Оsteocytes and osteoclasts

D.Оsteoblasts

E.Оsteoclasts*

In section of the tissue which contains cells without processes is submitted and everyone has ten nucleus. One of surfaces of cells has a goffered zone through which there is a secretion of hydrolyzed enzymes. What tissue is submitted in section?

A.Cartilage tissue

B.Epithelial tissue

C.Nervouse tissue

D.Bone tissue*

E.Muscle tissue

There is an increased loss of bone mass in older people, which shows the development of osteoporosis. Activation of what type of bone cells leads to the development of this disease?

AOsteoclasts*

BOsteoblasts

CMacrophages

16

 

 

D Basophils

 

 

E Osteocytes

 

 

 

16

Development of

On the Ro-gram of skeleton it is visible, that all three parts of pelvic bones are

 

bone tissues.

separated by intervals which answer an invisible cartilage on Ro-grams. It is typical of

 

 

what age?

 

 

A. To 25 years old

 

 

B. To 30 years old

 

 

C. To 16 years old*

 

 

D. Till 40 years old

 

 

E. To 50 years old

 

 

In course of indirect osteogenesis of tubular bone tissue a plate is formed between

 

 

epiphyseal and diaphyseal ossification centres that provides further lengthwise growth

 

 

of bones. What structure is it?

 

 

A Metaphyseal plate *

 

 

B Osseous cuff

 

 

C Osseous plate

 

 

D Osteon

 

 

E Layer of interior general plates

17

Development and

The regeneration process of damaged skeletal muscles іs very slow. What elements of

 

structure of

muscle fiber take part in the process of regeneration?

 

muscles tissues

A Myosatellitocytes*

 

 

B Myoblasts

 

 

C Smooth myocytes

 

 

D Myofibroblasts

 

 

E Myoepithelial cells

 

 

In clinical conditions trauma of skeletal muscles is diagnosed for the patient. The

 

 

fibers recycles slowly for the account:

 

 

A. Mitosis of the myosatelitocytes*

 

 

B.Division of the muscle fibres

 

 

C.Differentiation of fibroblasts

 

 

D. Increases in quantity amount of myofibrilles

 

 

E.Increases in quantity amount of sarcoplasm

In a phase of contraction of a myocardium (systole) in sarcoplasm of cardiomyocytes concentration of calcium’s ions sharply increases. What structures take part in deposition of calcium’s ions?

A.T - system

B.lysosomes

C.Ribosomes

D.L-system *

E.Nucleoles

At research of a cross-section of skeletal muscle fibers after mechanical trauma destruction thick myofilaments is observed. Where pathological changes will be located?

A.In a disk І

B.In a disk A*

C.In half of disk A

D.In disk A and in disk I

E.In half of disk I

At micropreparations of submandibular salivary glands there were the cells around the terminal parts and ducts that cover the serocyte and called mioepiteliocyte. What kind of tissue these cells belong to?

AMuscle*

BEpithelial

17

 

 

C Nervous

 

 

D Connective with special properties

 

 

E Loose connective

 

 

In histological preparation tissue is presented, the basic structural unit of which is fiber

 

 

that consists of symplast and satellite cells, covered by a basement membrane. For

 

 

what tissue this structure is characterized by?

 

 

A Skeletal muscle tissue *

 

 

B Smooth muscle tissue.

 

 

C Cardiac muscle tissue.

 

 

D Loose connective tissue.

 

 

E Reticular tissue.

 

 

At research of striated muscle fibers after the influence of hydrolytic enzymes

 

 

fracture of thin myofilaments was observed. Which structures have been damaged?

 

 

A Actin myofilaments *

 

 

B Tonofibrils

 

 

C T - Systems

 

 

D Sarcoplasmic reticulum

 

 

E Myosin miofilaments

 

 

Patient with injured muscles of the lower extremities was admitted to the

 

 

traumatological department. Due to what cells is reparative regeneration of the

 

 

muscle fibers and restoration of the muscle function possible?

 

 

A Satellite-cells*

 

 

B Myoblasts

 

 

C Myofibroblasts

 

 

D Fibroblasts

 

 

E Myoepithelial cells

 

 

The development of mesenchymal cells was inhibited in experiment. Development

 

 

which muscle tissue will be disturbed?

 

 

A Smooth muscle tissue*

 

 

B Muscle tissue neural origin

 

 

C Muscle tissue epidermal origin

 

 

D Cardiac muscle tissue

 

 

E Skeletal muscle tissue

 

 

Negative environmental factors have caused the dysfunction of myosatellite cells.

 

 

What function of the whole muscle fibre is likely to be changed in this case?

 

 

A Regeneration *

 

 

B Contraction

 

 

C Trophism

 

 

D Contractile thermogenesis

 

 

E Relaxation

 

 

 

18

Nervous tissue.

A sensitive neural ganglion consists of roundish neurocytes with one extension that

 

Neurons.

divides into axon and dendrite at some distance from the perikaryon. What are

 

Neuroglia.

these cells called?

 

 

A Pseudounipolar *

 

 

B Unipolar

 

 

C Bipolar

 

 

D Multipolar

 

 

E Apolar

 

 

 

19

Nervous fibres.

At traumatic damage probably development of degeneration of nervous fibers which is

 

Regeneration of

accompanied by breakage of axial cylinders, disintegration of myelin. Due to what

 

nervous fibres.

nervous structures there is a renewal of myelin at regeneration?

 

Nervous endings.

A. Gliocytes

18

 

Classification and

B. Shwann cells*

 

structure.

C. Peryneurium

 

 

D. Еndoneurium

 

 

E. Аstrocytes

 

 

In conditional experiment action of toxic substance breaks the mechanism of the

 

 

nervous impulse conduction. What structure provides performance of the given

 

 

function?

 

 

A. Neurolemma

 

 

B. Synaps *

 

 

C. Neurofibrills

 

 

D. Мitochondria

 

 

E. Nissle substance

 

 

 

20

Control of

 

 

mastering of the

 

 

submodule 2.

 

21

Final test control

 

 

of the module 1.

 

MODULE 2

 

TOPIC

TEST

1Nervous system. After amputation of the left top finiteness of the patient long time felt a strong pain Spinal cord. in it. What mechanism of formation of painful unhealthy sensations is most probable

Spinal ganglion.

in this case?

 

A. Fantomic *

 

B. Reflectory

 

C. Kausalgic

 

D. Hypoproduction of encephalines

 

E. Hyperproduction of encephalines

In a histological preparation the organ which will consist of grey and white substance is determined. The grey substance settles down in the center and will consist from radicular, associative neurons. Name body for which the given morphological attributes are characteristic.

A.Big hemispheres

B.Brain

C.Cerebellum

D.Spinal ganglia

E.Spinal cord*

In a histological preparation parenchyma of organ it is submitted by nervous fibers in which are determined pseudo-unipolar neurons. Neurons’ bodies are covered by glial and connective shalls, placed by groups. Named organ that has given morphological attributes.

A.Epiphysis

B.Spinal cord

C.Spinal ganglia *

D.Brain

E.Cerebellum

At a mechanical trauma the site of a peripheral nerve in length more than 10 sm is damaged injured. In result impellent activity of the top finiteness is broken.

Allotransplantation of criopreserved nerve is offered to the patient. What glial cells will take part in regeneration and maintenance of trophic the damaged injured site?

A.Microglial cells

B.Fibrous astrocytes

C.Neurolemmocytes *

D.Ependimogliocytes

19

 

 

E. Leucocytes

 

 

As a result of a trauma a patient has damaged anterior roots of spinal cord. What

 

 

structures have been affected?

 

 

A Axons of motoneurons and axons of neurons of lateral horns *

 

 

B Central processes of sensitive neurons of spinal ganglions

 

 

C Peripheral processes of sensitive spinal ganglions

 

 

D Axons of neurons of lateral horns

 

 

E Dendrites of neurons of spinal ganglions

 

 

 

2

Nervous system.

In a specimen that was coloured by method of silver impregnation some piriform cells

 

Cerebrum.

with 2-3 evident dendrites were found. What structure is being analysed?

 

Cerebellum.

A Cerebellar cortex*

 

 

B Spiral organ of middle ear

 

 

C Retina

 

 

D Cerebral cortex

 

 

E Spinal ganglion

One of sections of central nervous system has layerwise arrangement of neurocytes. Among them there are cells of the following forms: stellate, fusiform, horizontal, pyramidal. What section of central nervous system is this structure typical for?

ACortex of cerebrum*

BSpinal cord

CCerebellum

DMedulla oblongata

EHypothalamus

On preparation organ of nervous system which contains grey and white substance is submitted. The grey substance is placed on periphery. Neurons form three layers: molecular, ganglionar and granular. What organ is on preparation?

A.Brain cortex

B.Spinal cord

C.Spinal ganglia

D.Pons

E. Cerebellum cortex*

In a histological preparation the cut of precentral girus of the hemispheres is submitted. Specify, what layers are most advanced in this zone?

A.Molecular, pyramidal, ganglionar

B.Molecular

C.External and internal granular

D.Molecular and the layer of polymorphic cells

E.Pyramidal, ganglionar and a layer of polymorphic cells *

The alcoholic intoxication, as a rule, is accompanied by infringement of coordination of movement and balance, as a result of damage of structural elements of a cerebellum. Function of what cerebellum’s cells is broken first of all?

A.Stellate cells

B.Pyramidal cells

C.Fusiform cells

D.Pear-shaped cells*

E.Granular cells

In histological section, impregnated by salts of silver, determined the cerebellum cortex which contains pear-shaped, bascet-shape, stellate neurons, cells-grains. Named neurocytes which are part of the ganglionar layer.

A.Pear-shaped*

B.Stellate, pyramidal

C.Cells - grains, large stellate

20