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Genomics: The Science and Technology Behind the Human Genome Project.

Charles R. Cantor, Cassandra L. Smith

 

Copyright © 1999 John Wiley & Sons, Inc.

 

ISBNs: 0-471-59908-5 (Hardback); 0-471-22056-6 (Electronic)

APPENDIX

Databases

GenBank: A public database built and distributed by the National Center for Biotechnology Information.

http://www.ncbi.nlm.nih.gov/

ftp:ncbi.nlm.nih.gov

EMBL Nucleotide Sequence Database: A central activity of the European Bioinformatics Institute; an EMBL outstation.

http://www.ebi.ac.uk

ftp:ftp.ebi.ac.uk

DNA Data Bank of Japan (DDBJ): Activities began in earnest in 1986 in collaboration with EMBL and GenBank.

http://www.ddbj.nig.ac.jp/

ftp:ftp2.ddbj.nig.ac.jp

Genome Sequence DataBase (GSDB): Designed to meet the community-wide challenges of managing, interpreting, and using DNA sequence data at an ever increasing rate.

http://www.ncgr.org/gsdb

Protein Information Resource (PIR) and the PIR-International Protein Sequence Database:

http://www.nbrf.georgetown.edu

ftp:nbrf.georgetown.edu

MIPS: A database for protein sequences, homology data, and yeast genome information:

www.mips.embnet.org

SWISS-PROT protein sequence data bank and its supplement TrEMBL:

www.nlm.nih.gov (or EBI server)

Metabolic pathway collection:

www.cme.msu.edu/WIT/

NRSub database: ftp://biom3.univlyon1.fr/pub/nrsub ftp://ftp.nig.ac.jp/pub/db/nrsub

GDB Human Genome Database: http://gdbwww.gdb.org/ ftp://ftp.gdb.org/

Radiation Hybrid Database: http://www.ebi.ac.uk/RHdb ftp://ftp.ebi.ac.uk/pub/databases/RHdb

569

jpperra

570 APPENDIX

Mouse Genome Database (MGD): A comprehensive public resource of genetic, phenotypic, and genomic data.

ftp://www.informatics.jax.org/

ftp://ftp.informatics.jax.org/pub/

Molecular Probe Data Base (MPDB):

http://www.biotech.ist.unige.it/interlab/mpdb.html

Signal Recognition Particle Database (SPRDB): http://pegasus.uthct.edu/SRPDB/SRPDB.html ftp://diana.uthct.edu

Viroid and viroid-like sequence database: Addition of a hepatitis delta virus RNA section:

http://www.callisto.si.usherb.ca/

Mutation spectra database for bacterial and mammalian genes:

http://info.med.yale.edu/mutbase/

PRINTS protein fingerprint database: http://www.biochem.ucl.ac.uk/bsm/dbbrowser/ ftp://s-ind2.dl.ac.uk/pub/database/prints

PROSITE datases: http://expasy.hcuge.ch/ ftp.ebi.ac.uk

Blocks Database servers: http://blocks.fhcrc.org/ ftp://ncbi.nlm.nih.gov/repository/blocks

HSSP database of protein structure-sequence alignments: http://www.sander.embl-heidelberg.de/ ftp://ftp.embl-ebi.ac.uk/pub/databases/

Dali/FSSP classification of the three-dimensional protein folds: http://www.embl-heidelberg.de/dali/fssp/

DEF database of protein fold class predictions:

http://zeus.cs.uoi.gr/neural/biocomputing/def.html

SCOP: A structural classification of proteins database:

http://scop.mrc-lmb.cam.ac.uk/scop/

SBASE protein domain library: A collection of annotated protein sequence segments:

http://www.icgeb.triester.it http://base.icgeb.triester.it/sbase/(using BLAST)

Codon usage tabulated from the international DNA sequence databases: ftp://ftp.nig.ac.jp/pub/db/codon/current/

TransTerm: translational signal database:

http://biochem.otago.ac.nz:800/Transterm/homepage.html

REBASE: restriction enzymes and methylases:

http://www.neb.com/rebase

Ribonuclease P database:

http://www.mbio.ncsu.edu/RNaseP/home.html

APPENDIX 571

TRANSFAC, TRRD, and COMPEL: Toward a federated database system on transcriptional regulation:

http://transfac.gbf-braunschweig.de http://www.bionet.nsc.ru/TRRD

MHCPER: A database of MHC-binding peptides: http://wehih.wehi.edu.au/mhcpep/ ftp.wehi.edu.au/pub/biology/mhcpep/

Histone and histone fold sequences and structures:

http://www.ncbi.nlm.nih.gov/Basevani/HISTONES/

Directory of P450-containing Systems:

http://www.icgeb.trieste.it/p450

http://p450.abc.hu

O-GLYCBASE: A revised database of O-glycosylated proteins: http://www.cbs.dtu.dk/databases/OGLYCBASE/ ftp.cbs.dtu.dk/pub/Oglyc/Oglyc.base

Mitochondria

MITOMAP: Human mitochondrial genome database:

http://www.gen.emory.edu/mitomap.html

MmtDB: A Metazoa mitochondrial DNA variants database:

http://www.ba.cnr.it/ areamt08/MmtDBWWW.htm

IMGT: International ImMunoGeneTics database:

http://imgt.cnusc.fr:8104

SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis:

http://expasy.hcuge.ch/

GRBase: A database linking information on proteins involved in gene regulation: http://www.access.digex.net/ regulate ftp://ftp.trevigen.com/pub/Tfactors

ENZYME data bank:

http://expasy.hcuge.ch/

E. coli

 

 

 

Compilation of DNA sequences of

 

E. coli

K12: Description of the interactive

databases ECD and ECDC:

 

 

 

http://susi.bio.uni-giessen.de/usr/local/www/html/ecdc.html

 

EcoCyc: Encyclopedia of

E. coli

Genes and Metabolism:

http://www.ai.sri.com/ecocyc/ecocyc.html

 

 

 

GenProtEC: Genes and proteins of

 

E. coli

K12:

http://www.mbl.edu/html/ecoli.html

 

 

 

Yeast

Yeast Protein Database(YPD): A database for the complete proteome of

Saccharomyces cerevisiae:

http://www.proteome.com/YPDhome.html

LISTA, LISTA-HOP, and LISTA-HON: A comprehensive compilation of protein encoding sequences and its associated homology databases from the yeast

572 APPENDIX

Saccharomyces:

http://www.ch.embnet.org/

ftp://bioftp.unibas.ch

Drosophila

 

 

 

FlyBase: A

Drosophila

database:

 

http://flybase.bio.indiana.edu

 

 

ftp:flybase.bio.indiana.edu(in /flybase)

 

GIF-DB: A WWW database on gene interactions involved in

Drosophila

melanogaster

development:

 

 

http://www-biol.univ-mrs.fr/

lgpd/GIFTS_home_page.html

 

RNA

Compilation of 5S rRNA and 5S rRNA gene sequences: http://rose.man.poznan.pl/5SData/5SRNA.html http://www.chemie.fu-berlin.de/fb_chemie/ibc/agerdmann/5S_rRNA.html ftp.fu-berlin.de/science/biochem/db/5SrRNA

Small RNA database:

http://mbcr.bcm.tmc.edu/smallRNA/smallrna.html

uRNA database: http://pegasus.uthct.edu/uRNADB/uRNADB.html

guide RNA database:

 

http://www.biochem.mpg.de/

goeringe/

Ribosomal Database Project (RDP):

 

http://rdpwww.life.uiuc.edu/

 

ftp://rdp.life.uiuc.edu

 

Database on the structure of small ribosomal subunit RNA:

http://rrna.uia.ac.be/ssu/

Database on the structure of large ribosomal subunit RNA:

http://rrna.uia.ac.be/lsu/

RNA modification database: http://www-medlib.med.utah.edu/RNAmods/RNAmods.html ftp://medlib.med.utah.edu/library/RNAmods

Expansion of the 16S and 23S ribosomal RNA mutation databases (16SMDB and 23SMDB):

http://www.fandm.edu/Departments/Biology/Databases/RNA.html

Compilation of tRNA sequences and sequences of tRNA genes: ftp.ebi.ac.uk/pub/databases/tRNA

Specific gene Haemophilia:

Factor VIII Mutation Database on the WWW: The Haemophilia A Mutation, Search, Test, and Resource Site:

http://europium.mrc.rpms.ac.uk

ftp.ebi.ac.uk/pub/databases/hamsters

Haemophilia B: Database of point mutations and short additions and deletions:

http://www.umds.ac.uk/molgen/haemBdatabase

Database and software for the analysis of mutations in the human

human hpr t gene, and both the lacI, and lacZ gene in transgenic rodents: http://sunsite.unc.edu/dnam/mainpage.html

p53and APC gene mutations: Software and databases

Database of p53gene somatic mutations in human tumors and cell lines: http://www.ebi.ac.uk/srs/

Human

PAH mutation analysis consortium databases:

http://www.cf.ac.uk/uwcm/mg/hgmd0.html

alpha/beta fold family of proteins database and the cholinesterase gene server ESTHER:

http://www.ensam.inra.fr/cholinesterase

Marfan Database: Software and database for the analysis of mutations in the human FBN1 gene

BTKbase, mutation database for X-linked agammaglobulinemia (XLA):

http://www.helsinki.fi/science/signal/btkbase.html

Human type I collagen mutation database:

http://www.le.ac.uk/depts/ge/collagen/collagen.html

Receptors

Androgen receptor gene mutations database: http://www.mcgill.ca/andogendb/ ftp.ebi.ac.uk/pub/databases/androgen

Nuclear Receptor Resource Project:

http://nrr.georgetown.edu/nrr.html

Glucocorticoid receptor resource:

http://biochem1.basic-sci.georgetown.edu/grr/grr.html

APPENDIX 573

p53gene, the

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