Новые достижения в химии и химической технологии растительного сырья. Материалы III всероссийской конференции. Книга 2 [2007]

!"#$%&" 1. '#("#)*"++,- .(%/*"$$)0("1%2-/.%- 3"++,- 3$4 "+%$%3" 567

8"(".*-(%/*%."

:;<%(%2-/."4 1)(;=$" >)$-.=$4(+,? @-/ !-;<-("*=("

5$%+" @)$+,

!%< .(%/*"$$%2-/.)? (-A-*.% Space 0(=<<"

a (Å) b (Å) c (Å) B (°) ! (°)

" (°) V (Å3)

C$)*+)/*D (("//2%*"++"4) (;0/;3) 7)E11%&%-+* "#/)(#&%% (;;-1)

F (0 0 0)

F"G;-( .(%/*"$$" (;;)

# )#$"/*D 3$4 /#)(" 3"++,H '0("+%2%@"IJ%- %+3-./, C)$+)*" )#("#)*.% . #=25.99 >"./. % ;%+. <-(-3"2" 5"++,-/)0("+%2-+%4/<"(";-*(, C)."G"*-$D <(%0)3+)/*% <) F2 7)+-2+,- R %+3-./, [I>2L(I)] 6#/)$I*+,? /*(=.*=(+,? <"(";-*(

M"%#)$DA-- )*.$)+-+%- <%." % 4;,

R1=NOF0P–PFcO/NPF0P; wR2=N[w(F20–F2c)2/N[w(F20)2]1/

F%/. 1. ORTEP-

3%"0(";;" "+%$%3" 567 / @)3)()3+,- ;% "*);";%, <(-3- /*"@$-++,;% ;"- $-+D.%;% /1-(";% <()%G@)$D+)0) ("- 3%=/"

40

!"#$%&" 2. '(#)"**(+ ,$%*( % -.$( /012+3 ,$1 "*%$%," 456

4$%*( /012+3, Å

:%/.2. 7;"<808=*"1 ,%".)">>" "*%$%," 456

41

!"#$%$&'" #(!"%()"*#(" +,#$!$-"&!$*%( ,.#$#*(.(&$/,!(0 #,-1"!,

2.,. 3456785, ,.9. &5:;<=>, 9.,. +7=<?

!"! «#$%&%'(')%*'+ *,-'.&/0-&-1*%2),*3'&--4+ 5,6&7», 8/. 9)'6&*5,/0-,:, 2, #$%&%'(')%*–4, ;),%-&:)%*'+ *),+, 662544

(<&%%':) E-mail: radlesma@sandy.ru

!"#$%&'%-()&)$"&"*+#(), -+)(.", ()/0+') #% #1"-&)/" 1%$%2+') 3 %#'%34 1%$4*+'", 1-%#&56 )$("$"7%8%-'"$%356 90"-%3, (%&%-5+ 1-"- /+',:, " 3 ()*+#&3+ %&;4<+( 3 #%#&)3)6 1)-0:/+-'%-(%#/+&"*+#("6

#-+;#&3, " ()( 1-%/+24&%*'5+ #%+;"'+'", ;$, #"'&+7) #-+;#&3 7)="&5 -)#&+'">, 1+#&".";%3 " $+()-#&3+''56 1-+1)-)&%3.

?-%3+;+'% )$(%(#"$"-%3)'"+ ()/0+') %;'%)&%/'5/" #1"-&)/", "/+:="/" -)7$"*'4: #&-4(&4-4:

–1+-3"*'5/" #1"-&)/" ')#5=+''%@% -,;) $"'+>'%@% #&-%+'", – /+&)'%$%/, 9&)'%$%/, 1-%1)'%$%/-1, 84&)'%$%/-1, 1+'&)'%$%/-1, @+(- #)'%$%/-1, @+1&)'%$%/-1;

–1+-3"*'5/ #1"-&%/ ')#5=+''%@% -,;) -)73+&3$+''%@% #&-%+'",

–2-/+&"$1-%1)'%$%/-1 ("7%84&)'%$%/);

–1+-3"*'5/ #1"-&%/ '+')#5=+''%@% -,;) – 1-%1+'-2-%$%/ ()$- $"$%35/ #1"-&%/);

–1+-3"*'5/ #1"-&%/ )-%/)&"*+#(%@% -,;) – 8+'7"$%35/ #1"-&%/; A ()*+#&3+ ()&)$"7)&%-%3 1-%.+##) "74*+'5 /"'+-)$B'5+ ("#$%&5

H2SO4, H3PO4, HClO4, ) &)(2+ @+&+-%1%$"("#$%&5 (D?!) H4SiW12O40 " H7PW12O42. A -+74$B&)&+ 1-%3+;+''%> -)8%&5 4#&)'%3$+'%, *&% 1-"

37)"/%;+>#&3"" ()/0+') #% #1"-&)/" %#'%3'5/ 1-%;4(&%/ -+)(."" ,3$,+, #%%&3+&34:="> 1-%#&%> )$("$"7%8%-'"$%35> 90"-. E$(%(- #"$"-%3)'"+ ()/0+') – 1-%.+## %8-)&"/5>, *&% #$+;4+& "7 ("'+&"*+- #("6 ;)''56, 35,3$+''56 1% -+)(."" ()/0+') #% #1"-&)/" 3 1-"#4&- 3"" D?! " H2SO4:

42

!"#$%&'(, )&( *+, -$./012 3$4*5 '$2&-.+6'731 3(+$/5+.31 (/.38$') 1 1('.31 (%(+6#.&1-(#.''7$ 9-(&('7) #+1,'1$ -.%(-1&$+, (%91-&.) 3(4$& :7&6 (91%.'( 9-1 9(3(;1 %((&'(<$'1,:

=*$ k0 – /('%&.'&. %/(-(%&1 # %-$*$ % >=?, z·e– ".-,* 1('., r 1 r!– -.*15%7 1('. 1 ./&1#1-(#.''(=( /(39+$/%. %(($&%$''(. @&( %((&'(<$'1$ (%'(#.'( '. 5-.#'$'11 A(-'., /(&(-($ (9-$*$+,$& %#(:(*'5B C'&.+691B 9-1 9$-$3$;$'11 1('. # '$9-$-7#'(3 *1C+$/&-1/$ (% 9(%&(,''(2 *1- C+$/&-1)$%/(2 9-('10.$3(%&6B). D(%/(+6/5 (:7)'( r!>r, &( /('%&.'&. %/(-(%&1 *(+4'. 53$'6<.&6%, 9-1 5#$+1)$'11 *1C+$/&-1)$%/(2 9-('1-

0.$3(%&1 1 +1'$2'( /(--$+1-(#.&6 % #$+1)1'(2 &1 .

E./., +1'$2'., ".#1%13(%&6 /('%&.'&7 %/(-(%&1 (& "'.)$'1, *1- C+$/&-1)$%/(2 9-('10.$3(%&1 9(+5)$'. '.31 1 *+, -$./011 /.38$'. % 9$-#1)'731 .+18.&1)$%/131 %91-&.31 '(-3.+6'(=( %&-($'1,. D-1)$3 C&. ".#1%13(%&6, /./ 1 %+$*(#.+( (41*.&6, #79(+',$&%, *+, -."+1)'7F /.&.+1".&(-(# 1 &$39$-.&5- 9-(0$%%.. D(+5)$''7$ -$"5+6&.&7 9-1#$- *$'7 '. -1%5'/.F 1 1 2.

43

!"#$%&'(& )"*(+(,(-"./''01 !-"*$23". (4 5&-&630 5&-&40

6./. 2789:;<=>, &.6. -:?@AB9>, C.!. 6A=<D;<=>, 5.'. 2789:;<=

!"#$%$&$ '%(%% % '%(%)*#+,- $*'",.,/%% 01 234, &.. 567.6 867+#6 42, 576#",97#+, 660049 (2,##%9) E-mail: zenav@mail.ru

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

E% #A )35#< *"$#A,$%&'< +,-+()/+ 3!,28-%#30()$5/#-:*- 20(29)-(&(1) #-# %#30()3) 7():-#&$-3. F)$ /-$?&'6 D>#" :5/:/&$6 5#/-$)' # 7():-#&3:

CH3

H2C

CH3

CH3COO

H3C CH3

G(-;. %3&&$8$ #//-(%$,3+ +,-+-3/; "3A"37$)53 &$,$8$ /*$/$73 *$-:9(+ %#30()3)3 7():-#&3 &(*$/"(%/),(&&$ #A 7("(/)'.

!$ %3&&'1 BCHIJH, %#30()3) 7():-#&$-3 *"$+,-+() *"$)#,$- $*:<$-(,:. 35)#,&$/);. K35?( #1(.)/+ %3&&'( $ +"5$ ,'"3?(&&$1

44

!"#$"%&''&( )"*+,-.. )./0",/,/ 1",2#.'/ - +3/-'"'.. + &4.0./#5- '6( !"#$"%&''6( 73"7/3/,&( 4#/(.'/. 89-"+,'& $,& )./0",/, 1",2- #.'/ &1#/)/", %.7.7.)"(.$"+:.( )"*+,-."( [2].

;./0",/, 1",2#.'/ <-#<",+< +635"( )#< ('&%.= &3%/'.$"+:.= +.',"9&-, ,/:.= :/: 7$"'." 1",2#.'&-&* :.+#&,6, +"3&73&.9-&)'6= 1",2#.'/, +.',"9 30-/(.'&73&.9-&)'6= )./0",/,/ 1",2#.'/ . )32%.= [3].

>&-3"("''6" +7&+&16 7$"'.< )./0",/,/ 1",2#.'/ &+'&-/'6 '/ 3"/:0.<= /0",.#.3&-/'.< 1",2#.'/, -6)"#"''&%& .9 :&36 1"3"96. 89- -"+,'6 +7&+&16 7$"'.< )./0",/,/ 1",2#.'/ .9 1",2#.'/, :.7<$"'.- "( 1",2#.'/ - +("+. 7.3.).'/ . 2:+2+'&%& /'%.)3.)/, / ,/:!" 73. :.7<$"'.. 1",2#.'/ - +("+. 2:+2+'&* :.+#&,6 . 2:+2+'&%& /'%.)3.)/ [4]. ?/:!" .9-"+,"' (",&) 7$"'.< )./0",/,/ 1",2#.'/ /0",.#.3&- -/'."( 1",2#.'/ +("+5@ 2:+2+'&* :.+#&,6 . /0",/,&- +7.3,&- >1–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–6 $. D$"''6* 73&)2:, .("", - +-&"( +&+,/-" )& 93% ).- /0",/,/ 1",2#.'/. B")&+,/,:/(. )/''6= +7&+&1&- <-#<",+< .+7;&- -/'." ,&:+.$'6= . )&3&%&+,&<E.= =.(.:/,&-, '"&1=&).(&+,5 )&7'.- ,"#5'&* +,/).. – 7$"'.< 1",2#.'/ .9 1"3"+,6.

B/(. 73")#&!"'& )-/ +7&+&1/ 7$"'.< )./0",/,/ 1",2#.'/ .9 1"3"+,6.

D"3-6* +7&+&1 &+'&-/' '/ F:+,3/:0.. 1"3"+,6 - /77/3/," >&:+#"- ,/ «#")<'&*» 2:+2+'&* :.+#&,&*. 89("#5$"''/< 1"3"+,/ 7&("E/",+< - /77/3/, >&:+#",/ + 2:+2+'&* :.+#&,&*. D&+#" &$.+,:. /:,.-.3&-/''6( 2%#"( 3/+,-&3 -6#.-/",+< - =&)'2@ -&)2 . &,4.#5,3&-6-/",+< -6- +/!"''6* )./0",/, 1",2#.'/. D$"''6* 7&3&C&: +-",#&- :3"(&-&%& 0-",/ 73&(6-/",+< )& '"*,3/#5'&* 3"/:0.. . +2C.,+< - F:- +.:/,&3". A6=&) 7$"''&%& 73&)2:,/ +&+,/-#<", 35% &, (/++6 /.+. 1"3"+,6. G/++&-/< )< )./0",/,/ 1",2#.'/ - 7$"''&( 73&)2:,", +&+,/-#<", 1"" 98%. ?"(7"3/,23/ 7#/-#"'.< – 225 °>.

A,&3&* +7&+&1 &+'&-6-/",+< '/ -/3:" 1"3"+,6 - 2:+2+'&* :.+#&,". ;#< 73&-")"'.< F:+7"3.("',/ /1+@,'& +2=/< .9("#5$"''/< 1"3"+,/

45

(!"#$%&& 1–3 '') (&)* $+,$*-#. )/"/,0# ("#1'/"*' 3–10 ,') 2*'/3#- (#,4 - $"+5(*6*77+8 $*()+ , +$,+,7*9 $&,(*0*9 & $&2.0&(#,4 - 0/:/- 7&/ 7/,$*(4$&; :#,*-. <*,(/ *:&,0$& #$0&-&"*-#77=' +5(/' "#,0-*" -=(&-#(& - -*6+, 1#0/' *0!&(40"*-=-#(& -=,#>6/77=9 2"*6+$0. ?=- ;*6 2*(+:/77*5* 2"*6+$0# *0 '#,,= #.,. )/"/,0= ,*,0#-&( 35–38%. @#,,*-#. 6*(. 6%/0#0# )/0+(&7*(# - 2*(+:/77*' 2"*6+$0/ ,*,0#-(.- /0 92% 2"& &,2*(41*-#7&& &1'/(4:/77*9 !"#$%&& & 94% 2"& -#"$/ $+,$*-*9 )/"/,0=.

A0"*/7&/ ,&70/1&"*-#77*5* ,*/6&7/7&. 6*$#1#7* , &,2*(41*-#7&- /' ,*-"/'/77=; !&1&$*-;&'&:/,$&; '/0*6*- #7#(&1#: B@C 1D ,2/$- 0"*,$*2&& & 6#77=; E(/'/707*5* #7#(&1# (0#)(.).

<*(+:/77*/ -/3/,0-* &'//0 ,(/6+83&/ 6#77=/ 1D-B@C(CDCl3):

4,72 (1D, ', =AD2); 4,55 (1D, ', =AD2); 4,47 (1D, ', D3); 4,26 (1D, 6, J10,7 F%, D28); 3,86 (1D, 6, J10,7 F%, D28); 2,50 (1D, ', D19); 2,08(3D, ,,

AD3AG); 2,03 (3D, ,, AD3AG); 1,65; 1,02; 0,94; 0,82; 0,80 (-,/ 3D, ,,

AD3).

H$,2/"&'/70#(47=/ & 0/*"/0&:/,$&/ 6#77=/ 6%/0#0# )/0+(&7*(#

J(#5*6#". "#1"#)*0#77*'+ '/0*6+ 2*(+:/7&. 6%/0#0# )/0+(&7*- (# &1 )/"/,0= +6#(*,4 17#:&0/(47* +2"*,0&04 0/;7*(*5&8 2*(+:/7&. 6%/0#0# )/0+(&7#, # 0#$>/ +'/74K&04 1#0"#0= 7# 2"*&1-*6,0-*, 7/ ,7&>#. 2"& E0*' $#:/,0-# 2*(+:#/'*5* 2"*6+$0#.

!"#$%'%&

1.L(/;0/" G.J., D&5'#0+((&7# M.C., J#(0&7# M.N. & 6". <*(+:/7&/ )/0+- (&7*-*9 $&,(*0= &1 E$,0"#$0# )/0+(&7#. <"*0&-*-&"+,7#. & 2"*0&-*-

.1-/77#. #$0&-7*,04 7/$*0*"=; "*6,0-/77=; 0"&0/"2/7*&6*- // O&- '&$*-!#"'#%/-0&:/,$&9 >+"7#(. 2002. I. 36. P9. A. 26–28.

2.?#,&(/7$* Q.R., A/'/7:/7$* ?.L., L"*(*-# M.@. & 6". L#"'#$*(*5&- :/,$&/ ,-*9,0-# 0"&0/"2/7*&6*- $*"= )/"/1= // H$,2/"&'. & $(&7.

!#"'#$*(. 1993. I. 56. P4. A. 53–55

3.US 7041701. Triterpenoid derivatives. 09.04.2006.

4.M/-6#7,$&9 ?.N., S,4$&7 N.<., <*(/>#/-# D.T. ?=6/(/7&/ )/0+(&7# & ,+)/"&7# &1 $*"= )/"/1=, #$0&-&"*-#77*9 - +,(*-&.; «-1"=-7*5* #-- 0*5&6"*(&1#» // O&'&. "#,0&0/(47*5* ,="4.. 1998. P1. A. 5–9.

46

!"#$%& #'()* +,"-'( .%$/0"#1

$.". 234561, ..#. 2789:;3<2

1!"#"$%&"' ()*)$+,-./' 0."1)$%"2)2, 3$. !14#4*./',79,

5$+%.46$%&, 660041 (74%%"6) E-mail: kogay@lan.krasu.ru

28.%2"202 9":"" " 9":";)%&4' 2)9.4,4<"" != 7>?, >&+*):<4$4*4&, 5$+%.46$%&, 660036 (74%%"6)

!"#$"%% &'()* +,-. /#-#0. – /#-#()' –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

B454(+'% 5,84@4+'64% <-4-,8".9 /4,1,74(+4 '+)4?".9 (,- #84"#"4: <-4?,84) ? -%8# (12&'#? + 4")#-#(".5 -#021*)')'5 – ",?.# (,#84"#"4% <-,%?1%=) /,1## (41*"2= /4,1,74(+2= '+)4?",()*. C'+, 3,28-D-/4(-845#)41(2+64"') /#)214"' ,/1'8'#) '")4-!EF-1 '+)4?",- ()*= [1]. G4(7#54@)'1') /#)214"' <-,%?1%#) ?.(,+2= <-,)4?,?4-2(- "2= '+)4?",()* ? (,)'"44 ( 4552",()45214-2=A45 8#:()?4#5 [2]. H#<'),<-,)#+),-".54, '")4,+(48'")".54 4 <-,)4?,?,(<'14)#1*".54 (?,:()?'54 ,/1'8'#) -%8 8-2749 '641'),? /#)214"' [3, 4].

! "'(),%A## ?-#5% ?,0"4+1' "#,/9,845,()* ? -'($4-#"44 '((,-- )45#")' '641*".9 <-,40?,8".9 /#)214"' 81% <,4(+' /,1## ;@@#+)4?- ".9 1#+'-()?#"".9 <-#<'-'),?. I ;),: 6#1*= "'54 /.14 (4")#04-,?'- ". ",?.# 5,",- 4 84'641*".# <-,40?,8".# /#)214"'.

J-,?#8#", '6414-,?'"4# /#)214"' 91,-'"748-48'54 1-'8'5'")'"- +'-/,",?,:, 748-,+,-4&",:, +'<-41,?,: +4(1,) 4 91,-'"748-48,5 91,-748-')' !-'54",/#"0,:",: +4(1,).. !(# 91,-'"748-48., (4")#04- -,?'". <, 5#),84+# [5] 40 (,,)?#)()?2=A49 +4(1,) 4 <%)491,-4(),7, @,(@,-'. K6414-,?'"4# /#)214"' <-,?,8414 ? (29,5 /#"0,1# ? <-4- (2)()?44 /#0?,8",7, <4-484"' <-4 0 ºI ( <,()#<#"".5 "'7-#?'"4#5 (5#(4 8, 20 ºI ((9#5' 1).

47

!""#$"%&$'& ()*'$+ ' ,*"-+$.'/-'/+ 0'1*"#2 1"1#+3*4*" 1 : 2 3" 31&, "52#+, 6"/ -&+07'' ' 8'1#"#) 5"*)8&$$2, 1"&/'$&$'9 0"$#-"- *'-"3+*' :"/": ;!6 $+ 5*+1#'$0+, Silufol UV-254 1 '15"*<="3+$'&: 1'1#&:2 ,*"-">"-: – :+$"* – :)-+3<'$+4 0'1*"#+ (100 : 2 : 0,5). ?2- /&*&$$2& '= -&+07'"$$"9 1:&1' 5-"/)0#2 +7'*'-"3+$'4 "8'@+*' :"- /": 5-&5+-+#'3$"9 #"$0"1*"9$"9 ,-":+#".-+>'' $+ 1'*'0+.&*&. ? 0+8&- 1#3& A*B&$#+ '15"*<="3+*' ,*"-">"-:. C&1"-(7'B 5-"/)0#"3 +7'*'-"- 3+$'4 5-"3"/'*' :'*+7+#":. D"1*& "#."$0' :'*+7+#+, 5-"/)0#2 +7'*'-"3+$'4 /"5"*$'#&*<$" "8'@+*' 5&-&0-'1#+**'=+7'&9. !#-"&$'& 5"*)8&$$2, 1"&/'$&$'9 )1#+$+3*'3+*' :"/+:' EF- ' DGH- 15&0#-"10"5'', 5"/#3&-I/+*' A*&:&$#$2: +$+*'=":.

CH2OH RCOCl

C5H5N, C6H6

HO

O

CH2O-C

R

R2O

R = 1-+/+:+$#'*-; (2->&$'*)A#'*-; !-+:'$">&$'*-; .&5#'*- , + – R2 = J '*' R-CK !,&:+ 1

EF-15&0#-2 =+5'1+$2 $+ 5-'("-& «Vektor-22» 3 #+(*+, KBr, 15&0#-2 LGH (1J)- $+ 5-'("-& «Avance 200» >'-:2 Bruker 3 /&9#&-"- ,*"-">"-:&.

?-&=)*<#+#& 3=+':"/&91#3'4 ()*'$+ 1 ,*"-+$.'/-'/+:' 1-+/+:+$#+$0+-("$"3"9, .'/-"0"-'8$"9 0'1*"# ' ,*"-+$.'/-'/": ,*"--

.'/-+#+ 5-+:'$"(&$="9$"9 0'1*"#2 1'$#&='-"3+$2 :"$"A>'-2 ()*'$+: 28-K-1-+/+:+$#+#, 28-K-.'/-"7'$$+:+# ' 28-K-5-+:'$"(&$="+#. K(-+="3+- $'& :"$"A>'-"3 5"/#3&-I/&$" /+$$2:' EF ' DGH 15&0#-"10"5''.

?EF-15&0#-+, 5"*)8&$$2, 1"&/'$&$'9 "#1)#1#3) 5"*"1+ 5"-

.*"@&$'4, 1""#3#3)B@+4 3+*&$#$2: 0"*&(+$'4: 0+-("$'*<$"9

.-)552 '1,"/$2, ,*"-+$.'/-'/"3, ' 5"43*4B#14 5"*"12 5".*"@&$'4, 1""#3#3)B@'& 3+*&$#$2: 0"*&(+$'4: 0+-("$'*<$"9 .-)552 ' !–K

48

!"#$% !&'()*+ ,-%.'". /01, )02.%34., " 56-!2417.4 2.'89170 0:%&%-

.'"0)%# ;479&%)0 +&'.0)<%8.%8'3 1-08030)70)10.;')'"'= 1%!&'7* 2.%!97!7"947 2'&'!0 2'<&'>4)%# 2.% 1718,5 !3-1, !''7"47!7"9?>0# "0&4)7)*3 1'&4;0)%#3 !&'()',-%.)'= 10.;')%&@)'= <.922*. A0))0# 2'&'!0 2'<&'>4)%# '7!97!7"947 " 56-!2417.4 ;479&%)0. B'&'!0 2'<&'- >4)%# 2.% 1231 !3-1 !''7"47!7"947 "0&4)7)*3 1'&4;0)%#3 !"#$% C–D !&'()',-%.)'= <.922*. E 2.'89174 0:%&%.'"0)%# '7!97!7"947 2'&'!0 2'<&'>4)%# 2.% 1788 !3-1, !''7"47!7"9?>0# "0&4)7)*3 1'&4;0)%#3 10.;')%&@)'= <.922* +&'.0)<%8.%80 1-08030)70)10.;')'"'= 1%!&'7* %, 1.'34 7'<', '7!97!7"947 2'&'!0 2'<&'>4)%# 2.% 1693,5 !3-1, !''7"47- !7"9?>0# "0&4)7)*3 1'&4;0)%#3 10.;')%&@)'= <.922* 1-08030)70)- 10.;')'"'= 1%!&'7*.

E BFG !2417.0+ 0)0&%$%.943*+ !'48%)4)%= )0;&?8047!# !8"%< !%<)0&'" 347%&4)'"*+ 2.'7')'" 2.% C28 " ';&0!7@ ;'&44 !&0;'<' 2'. (4,26 3.8.; 4,32 3.8.; 3,86 3.8.% 3,81 3.8.) 2' !.0")4)%? ! !%<)0&03% ,7%+ 2.'7')'" " ;479&%)4 (3,78 3.8.; 3,83 3.8.; 3,37 3.8 % 3,31 3.8.), H7' !"%- 8474&@!7"947 ' 2'#"&4)%% .#8'3 ! 347%&4)'"*3% 2.'7')03% ;'&44 84- $,1.0)%.9?>4<' $034!7%74, H43 DI-<.9220. /01'= <.922'= " 80))'3 !&9H04 #"/!# 10.;'1!%&@)0# <.9220 1%!&'7.

A'10$074&@!7"'3 7'<', H7' 2'&9H4))*4 !'48%)4)%# – ,7' 3')'- ,-%.* ;479&%)0, !&9(%7 '7!97!7"%4 )%$1'2'&@)'<' !8"%<0 !%<)0&0 2.'7')0 2.% C3 2' !.0")4)%? ! !%<)0&'3 ,7'<' 2.'7')0 " ;479&%)4 (')% %84)7%H)* % !'!70"?7 3,21 3.8.).

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

3,28-D-8%102.%&07 ;479&%)0: C, % "*H. 79,31 ()0=84)' 77,83); I, % "*H. 11,49, ()0=84)' 10,86).

49