Psychodermatology has gained momentum and interest among medical disciplines in recent years, even though its origins go back a long way, as philosophers and physicians described the rst psychodermatological cases in ancient times [3, 4]. The rst case described in history seems to date back to the eighteenth century B.C. and concerns a Persian prince who developed a skin condition (compatible with what we now call “psoriasis”) due to the stress he felt about his imminent suc­cession to the royal throne [5]. In the fourth century B.C., Hippocrates described cases of people who had pulled out their hair due to stress, describing a clinical picture that corresponds to what we know today as “trichotillomania” [6]. In the same century, Aristotle recognized the role of the inseparability of the mind and the skin, considering them as two complementary and inseparable entities [3]. Anecdotal cases are also reported in sacred texts. Descriptions of trichotillomania were men­tioned in the Bible [3, 7], and the ancient Buddhist texts transmit the story of a woman whom Buddha taught to control her anger to improve her skin disease [8]. More recently, in the eighteenth century, the dermatologist Robert Willan described a patient who was convinced he had skin parasites that were causing him harm (describing the condition we would now call “delusional parasitosis”) [3]. Interest in this disorder continued in the following centuries. In the twentieth century, the neurologist Karl Axel Ekbom studied the difference between insect phobia and delusional parasitosis, which was later denitively dened in 1946 with this termi­nology [3]. In recent centuries, the close connection between skin and mind has been increasingly explored. In his book, the dermatologist William James Erasmus Wilson described some the so-called skin neurosis" (such as alopecia areata, hyper­hidrosis, pruritus, and delirious infestation) and investigated the relationship between these manifestations and depressive and anxious states [3, 9]. In 1933, the dermatologist John Thornton Ingram stated that the skin is an extension of the mind and that, consequently, an assessment of the external condition of the skin should be performed to obtain a complete evaluation of a person’s personality [10].