Nanomedicines are the applications of nanotechnology to achieve innovation in research or use of nano level measuring unit materials in the detection, prognosis, therapy and cure of disease. It makes use of the properties created by materials at its nanoscale level of 10-9 m, which often differ from the same substance at a larger size in terms of biology, physics and chemistry. Nanoparticles are important components of nanomedicine and have attracted a lot of attention as potential delivery systems of drugs for cancer diagnostics and therapy. Nanoparticles are potential therapeutic carrier system, limited oral bioavailability, and circulatory instability, insufficient tissues distribution and toxicity are some practically use challenges that have yet to be addressed. Nanoparticle will continue to open many advantages and emerge new biological applications due to their small size, customizable surface, enhanced solubility, and multi-functionality (Singh and Lillard Jr, 2009). Nanoparticles also have the advantage of becom­ing more suitable for intravenous delivery than larger microparticles (Bhattacharjee et al., 2010). The development of a number of innovative drug-delivery methods for targeting tumor has been supported by technological breakthroughs in the disciplines of biomaterials, polymer chemistry, and drug-delivery techniques (Wood et al., 2010). Nanotechnology has been extensively investigated and used for cancer treatment because nanoparticles can play a vital role as a drug delivery mechanism Nanoparticle-based drug delivery provides several advantages over traditional drug delivery, including greater stability and biocompatibility, increased permeability and retention effect, and precision targeting. Due to the gen­eral applicability development of hybrid nanoparticles, which integrate the characteristics of numerous nanoparticles, this type of drug-carrier system has evolved to the next level (Yao et al., 2020).