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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_1100_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Foreword
- •Preface
- •Contents
- •Contributors
- •Part I
- •Esophageal Surgery
- •Tracheo-Esophageal Fistula
- •Overview
- •Etiology
- •Clinical Presentation
- •Diagnosis
- •Management
- •Conservative Management
- •Endoscopic Management
- •Operative Management
- •Postesophagectomy TEF
- •Postintubation TEF
- •Bronchoesophageal Fistula
- •Prevention of Tracheoesophageal Fistula
- •Outcomes
- •Conclusion
- •Five Key Points to Avoid Complications
- •Five Key Points to Diagnose or Manage Complications Intra or Postoperatively
- •References
- •Esophageal Strictures Refractory to Endoscopic Dilatation
- •Introduction
- •Etiology of Esophageal Strictures
- •Treatment
- •Treatment of Benign Esophageal Strictures
- •Nonsurgical Options
- •Endoscopic Dilatation
- •Steroid Injection
- •Esophageal Stenting
- •Rendez-Vous Procedure
- •Incisional Therapy
- •Surgical Options
- •Antireflux Surgery for Peptic Strictures
- •Esophagectomy
- •Malignant Esophageal Strictures
- •Endoscopic Treatment
- •Dilatation
- •Stent Placement
- •Laser Therapy
- •Brachytherapy
- •Chemotherapy and Radiation Therapy
- •Surgical Treatment
- •Conclusion
- •Key Points for Avoiding Postsurgical Esophageal Strictures
- •Key Points for Managing Esophageal Strictures
- •References
- •Esophageal Anastomotic Leak
- •Introduction
- •Risk Factors for Anastomotic Leak
- •Presentation and Identification of a Leak
- •Prevention and Management of Anastomotic Leaks
- •Future Directions
- •Conclusion
- •Key Points on Avoiding an Esophageal Anastomotic Leak
- •Key Points on Diagnosis and Managing an Esophageal Anastomotic Leak
- •References
- •Transhiatal Esophagectomy—Intraoperative Disasters
- •Introduction
- •Preoperative Risk Factors for Bleeding with a THE
- •General Considerations
- •Anesthetic Considerations
- •Conduct of the Operation
- •Bleeding Scenarios During THE
- •Tracheal Tear
- •Summary
- •Key Points: Avoiding Catastrophic Complications—Mediastinal Bleeding and Airway Injury—During Transhiatal Esophagectomy
- •Key Points: Diagnosing and Managing Catastrophic Complications—Mediastinal Bleeding and Airway Injury—During Transhiatal Esophagectomy
- •References
- •Chyle Leak After Esophageal Surgery
- •Introduction
- •Historical Review
- •Basic Science
- •Embryology
- •Anatomy
- •Physiology
- •Composition of Chyle
- •Chylothorax
- •Etiology/Cause
- •Post-esophagectomy Chylothorax
- •Diagnosis
- •Clinical Features
- •Fluid Studies
- •Imaging
- •Treatment
- •Conservative Management
- •Surgical Management
- •Summary
- •Key Points on Avoiding an Esophageal Anastomotic Leak
- •Key Points on Diagnosis and Managing an Esophageal Anastomotic Leak
- •References
- •Evaluation of the Vocal Cords
- •Treatment of Unilateral Vocal Cord Dysfunction
- •Injection Augmentation
- •Framework Surgery for Unilateral Vocal Cord Dysfunction
- •Treatment of Bilateral Vocal Paralysis
- •Key Summary Points
- •References
- •Introduction
- •Pathophysiology
- •Classification
- •Symptoms
- •Diagnosis
- •Management of Airway, Hoarseness, and Vocal Cord Dysfunction After Esophagectomy
- •Introduction
- •Vocal Fold Dysfunction
- •Symptoms of Unilateral Vocal Cord Dysfunction
- •Symptoms of Bilateral Vocal Cord Dysfunction
- •Treatment
- •Complications
- •Conclusion
- •Five Key Points on How to Avoid Complications
- •Five Key Points on Diagnosing and/or Managing the Complications Either Intraoperatively or Postoperatively
- •References
- •Intraoperative Solutions for the Gastric Conduit that Will Not Reach
- •Colon as an Alternative Conduit
- •Jejunum as an Alternative Conduit
- •Pedicled Jejunal Interposition
- •Free Jejunal Interposition
- •Summary
- •Key Points
- •References
- •Injury to the Right Gastroepiploic Artery
- •Introduction
- •Anatomy of the RGEA
- •Vascular Considerations in Esophagectomy
- •Preoperative Evaluation of the RGEA
- •Preparation and Mobilization of the Gastric Conduit
- •Techniques for Improving Tissue Oxygenation
- •Tension-Free Anastomosis
- •“Supercharging”
- •Venous Drainage
- •Conclusion
- •Five Key Points: Avoiding Injury to the Right Gastroepiploic Artery
- •References
- •Intra-Operative Solutions for Ischemic Gastric Conduit
- •Gastric Esophageal Replacement Conduit
- •Diagnosis of Gastric Conduit Ischemia
- •Summary
- •Key Points for Avoiding Gastric Conduit Necrosis
- •Key Points for Managing Gastric Conduit Necrosis Postoperatively
- •References
- •Jejunal Feeding Tube Complications
- •Introduction
- •Technique for Placement
- •Open Surgical Jejunostomy Tubes
- •Laparoscopic Jejunostomy Tubes
- •Complications
- •Bowel Necrosis
- •Bowel Obstruction
- •Tube Dysfunction
- •Infectious Complications
- •Aspiration
- •Conclusion
- •Key Points
- •References
- •Part II
- •Gastric Surgery
- •Gastroparesis
- •Etiology
- •Clinical Presentation and Evaluation
- •Management
- •Bile Reflux
- •Etiology
- •Clinical Presentation and Evaluation
- •Management
- •Conclusion
- •Key Points (Prevention)
- •Key Points (Management)
- •References
- •Dealing with Dumping Syndrome
- •Introduction
- •Diagnosis
- •Prevention
- •Management of Dumping Syndrome
- •Diet
- •Pharmacologic Therapy
- •Acarbose
- •Somatostatin Analogs
- •Studies of the Fast-Acting Somatostatin Analog Octreotide
- •Studies of Long-Acting Octreotide LAR
- •Adverse Effects of Somatostatin Analogs
- •Surgical Treatment
- •Conversion of Billroth II to Billroth I Anastomosis
- •Roux-en-Y Conversion
- •Continuous Enteral Feeding
- •Conclusion
- •Key Points
- •References
- •Introduction
- •Epidemiology
- •Etiology
- •Pathophysiology
- •Clinical History
- •Physical Findings
- •Differential Diagnosis
- •Diagnosis
- •Noninvasive Imaging Studies
- •Treatment
- •Medical Treatment
- •Endoscopic/Interventional Radiology
- •Surgical Intervention
- •Summary
- •Key Points for Avoiding
- •Key Points for Diagnosing/Managing
- •References
- •Duodenal Stump Blowout
- •Introduction
- •Clinical Presentation of Blowout
- •Mechanisms Contributing to Blowout
- •Staple Line Failure
- •Distal Obstruction
- •Malnutrition
- •The Difficult Duodenum
- •Techniques for Reducing the Risk of Blowout
- •Management of the Difficult Duodenum
- •General Principles of Closure
- •Nissen Technique
- •Bancroft Technique
- •Tube Duodenostomy and Drainage
- •Management of Stump Blowout
- •Medical Management
- •Percutaneous Radiologic Techniques
- •The Decision to Operate and Surgical Approach
- •Summary of Management
- •Ramifications of Blowout
- •Conclusions
- •Key Points: Avoiding Duodenal Stump Blowout
- •Key Points: Diagnosing and Managing Stump Blowout
- •References
- •Postoperative Complications After Surgery for Gastric Cancer: Anastomotic Leakage
- •Introduction
- •Incidence
- •Prospective Factors
- •Detection
- •Differential Diagnosis
- •General Management
- •External Drainage
- •Treatment of the Leakage Site
- •Duodenal Stump Leakage
- •Summary
- •Five Key Points to Avoid Anastomotic Leakage
- •Five Key Points to Diagnose and Manage Leakage
- •References
- •Part III
- •Hepatobiliary and Pancreatic Surgery
- •Introduction
- •Definition of PHI
- •Risk Factors for PHI
- •Prevention of PHI
- •Systematic Volumetry of the “Fully Functioning” Part of the Liver
- •Portal Vein Embolization
- •Limiting the Duration of Preoperative Chemotherapy
- •Treatment of PHI
- •Conclusion
- •Key Points
- •References
- •Biliary Leaks and Thoracobiliary Fistula
- •Introduction
- •Definitions
- •Biliary Leak and Grading System
- •Controlled and Uncontrolled Biliary Leaks
- •Source
- •Risk Factors and Prevention
- •Prevention
- •Risk Factors for Bile Leaks After Extrahepatic Bilioenteric Anastomosis
- •Prevention
- •Risk Factors for Bile Leak After Liver Resection
- •Prevention of Biliary Leaks After Hepatectomy
- •Intraoperative Tests for Bile Leaks
- •Postoperative Drains
- •Diagnosis
- •Investigations
- •Ultrasonography or CT Scan
- •Fistulogram
- •MRC, ERC, and PTC
- •HIDA
- •Management
- •Medical Management
- •Endoscopic Management
- •Interventional Radiology
- •Combined Endoscopic and Interventional Radiology Approaches—Rendezvous Procedures
- •Thoracobiliary Fistula
- •Diagnosis
- •Treatment
- •Five Key Points to Avoid Complications
- •Five Key Points to Diagnosis or Manage Complications
- •References
- •Contralateral Bile Duct Injury During Hepatic Resection
- •Introduction
- •Etiology and Risk Factors
- •Anatomical Variations
- •Difficult Surgical Resection and Reoperation
- •Type of Liver Resection
- •Aggressive Dissection and Devascularization of Bile Ducts
- •Initial Investigations and Management
- •Initial Investigations
- •Stabilization and Operative Planning
- •No Evidence of Distal Obstruction with Fistula
- •Evidence of Distal Obstruction with Fistula
- •Evidence of Distal Obstruction but no Fistula
- •Definitive Management
- •Anatomy Relevant to Operative Repair of Biliary Outflow of Remnant
- •Operative Repair
- •Repair of Injury to Right Liver Outflow
- •Repair of Injury to Left Liver Outflow
- •Prevention of Contralateral Bile Duct Injury
- •Attention to Variation in Biliary
- •Intrahepatic Control of Biliary Radicals
- •Tumor Close to the Hilum
- •Outcomes
- •Five Key Points to Avoid Contralateral Bile Duct Injury
- •Five Key Points to Diagnose and Treat Contralateral Bile Duct Injury
- •References
- •Massive Intraoperative Hemorrhage During Hepato-Biliary and Pancreatic Surgery
- •Introduction
- •Hemorrhage During Liver Surgery
- •Magnitude of Problem
- •Hepatic Vascular Anatomy
- •Prevention of Major Hemorrhage During Hepatic Resection
- •Techniques Aimed at Reducing Blood Loss During Hepatic Surgery
- •Deliberate Dissection and Exposure of Retro-Hepatic Vena Cava and Major Hepatic Veins
- •Hepatic Inflow Control
- •Vascular Isolation
- •Acute Normovolemic Hemodilution (ANH)
- •Management of Intra-Operating Bleeding During Liver Resection
- •Massive Hemorrhage During Pancreatic Surgery
- •Pancreatic Anatomy
- •Bleeding During Pancreaticoduodenectomy
- •Summary
- •5 Key Points to Avoid Complications
- •References
- •Intraoperative Injury to Hepatic Arterial Structures
- •Introduction
- •Normal Anatomy of the Hepatic Arterial Vasculature
- •Variant Anatomy of the Hepatic Arterial Vasculature
- •Replaced and Accessory Right Hepatic Arteries
- •Replaced and Accessory Left Hepatic Arteries
- •Replaced Common Hepatic Artery
- •Celiac Artery Stenosis
- •Preoperative Radiographic Assessment
- •Preoperative Considerations
- •Intraoperative Considerations
- •Specific Intraoperative Considerations
- •Pancreaticoduodenectomy (PD)
- •Replaced/Accessory Right Hepatic Artery
- •Replaced Common Hepatic Artery
- •Celiac Artery Stenosis
- •Hemi-hepatectomy
- •Conclusions
- •Key Points: Preoperative Interventions
- •Key Points: Intraoperative Principles
- •References
- •Hepatic Abscess
- •Etiology
- •Diagnosis
- •Computed Tomography
- •Ultrasound
- •Magnetic Resonance Imaging
- •Treatment
- •Five Key Points on How to Avoid Complications
- •Five Separate Key Points on Diagnosing and/or Managing the Complication
- •References
- •Hepaticojejunostomy Anastomotic Strictures
- •Introduction
- •Diagnosis
- •Clinical and Biological Presentation
- •Morphological Evaluation
- •Incidence and Risk Factors According to the Clinical Context
- •Iatrogenic Bile Duct Injury
- •Liver Transplantation (LT)
- •Pancreatic Head Resection
- •Choledochal Cyst
- •Therapeutic Options
- •Conservative Management
- •Choice of the Approach
- •To Stent or Not to Stent?
- •Periprocedural Management
- •Surgery
- •Revisionary Surgery
- •Liver Resection
- •Liver Transplantation (LT)
- •Key Points: How to Avoid HJ Stricture
- •Key Points: Diagnostic and Management
- •References
- •Defining Pancreatico-Jejunostomy Strictures (PJS) and Pancreatico-Jejunostomy Strictures (PGS) by Symptoms, Morphology and Function
- •Management of Intractable Pain Due to PJA or PGS Stenosis in Surgical Case Series
- •Endoscopic Techniques for Management of PJA Strictures
- •Technical Clinical Results for ERP
- •EUS-Guided Access and Drainage
- •EUS-Guided Rendezvous
- •Pancreatic Antegrade Needle Knife (PANK) Technique
- •EUS-Guided Pancreatogastrostomy
- •Jejunal Stenosis Mimicking PJA Stenosis
- •Conclusions
- •Key Points
- •References
- •Postoperative Portal, Mesenteric, and Splenic Vein Thrombosis
- •Introduction
- •Pathophysiology
- •Diagnosis: Clinical Manifestations and Blood Tests
- •Diagnosis: Imaging Tests
- •Treatment
- •Anticoagulation
- •Interventional Techniques
- •Surgery
- •Conclusion
- •Key Points for Diagnosis
- •Key Points for Treatment
- •References
- •Postpancreatectomy Hemorrhage: Early and Late
- •Introduction
- •Prevention of Late PPH
- •The Falciform Ligament
- •The Portal Dissection
- •GDA Ligation
- •Reinforcing the Pancreatic Transection Site (Distal Pancreatectomy)
- •Diagnosis of Late PPH
- •Symptoms/Signs
- •Imaging for Late PPH
- •Management of PPH
- •Early PPH
- •Late PPH
- •Conclusion
- •Key Points to Avoid Complications
- •Key Points to Diagnose/Manage
- •References
- •Major Disruptions of Pancreaticojejunostomy
- •Introduction
- •Conclusion
- •Key Points: How to Avoid Complications
- •Key Points: Diagnosis/Management
- •References
- •Persistent Pancreatic Fistula
- •Introduction
- •Definition of Pancreatic Fistula
- •Procedure-Specific Incidence and Risk Factors for Pancreatic Fistula
- •Pancreaticoduodenectomy
- •Distal Pancretectomy
- •Duodenum-Preserving Pancreatic Head Resection/Lateral Pancreaticojejunostomy
- •Pancreatic Pseudocyst Drainage/Pancreatic Necrosectomy
- •Other Pancreatic Resections
- •Prevention of Pancreatic Fistula
- •Complications of Pancreatic Fistula
- •Management of Pancreatic Fistula
- •Initial Management
- •Delineation of Pancreatic Duct
- •Definitive Treatment of Pancreatic Fistula
- •Operative Management of Pancreatic Fistula
- •Conclusion
- •Key Points to Avoid Complications
- •Key Points: Diagnosing and/or Managing Complications Either Intra- or Postoperatively
- •References
- •Management of Chyle Leaks Following Pancreatic Resection
- •Introduction
- •Background
- •Anatomy and Physiology of Visceral Lymphatics
- •Diagnosis of a Chyle Leak
- •Management of a Chyle Leak
- •The Contained Chyle Leak
- •Chylous Ascites
- •Management of Refractory Chyle Leaks
- •Conclusion
- •Key Points in Managing a Chyle Leak
- •References
- •Overview
- •Diagnosis
- •Prevention
- •Identifying Risk Factors
- •Role of Octreotide
- •Role of Pancreatic Stenting
- •Dissection and Management of the Pancreatic Stump
- •Minimally Invasive Versus Open Techniques
- •Drain Placement and Management
- •Management of Complications of Pancreatic Leak
- •Goal-Directed Resuscitation and Infection Control
- •Further Definition of Anatomy and Source Control
- •Optimizing Patient Clinical Status for Ongoing Conservative Management
- •Deliberate Reintervention When Clinically Indicated
- •Summary
- •Key Points on Avoiding Complications
- •Key Points on Diagnosis/Management of Complications
- •References
- •Part IV
- •Colorectal Surgery
- •Pearls for the Small Bowel and Colon That Will Not Reach
- •Introduction
- •Anatomic Constraints
- •Diagnosing the Problem
- •Specific Techniques: Making It Reach
- •Colorectal and Coloanal Anastomosis
- •Lateral-to-Medial Approach
- •Medial-to-Lateral Approach
- •Ileal-Pouch Anal Anastomosis (IPAA)
- •Stomas that Do Not Reach
- •Bailout Maneuvers—It Just Does Not Reach
- •Conclusions
- •Key Points on How to Avoid the Complication
- •Key Points on Diagnosing/Managing the Complication
- •References
- •Anastomotic Leak/Pelvic Abscess
- •Introduction
- •Prevention
- •Diagnosis and Management
- •Diagnosis
- •Management
- •Type I: Generalized Peritonitis
- •Type II: Localized Pelvic Abscess
- •Type III: Fistula
- •Long-Term Outcome
- •Need for a Permanent Stoma
- •Stenosis or Stricture
- •Local Recurrence
- •References
- •Management of Anastomotic Stricture
- •Introduction
- •Etiology of Anastomotic Stricture
- •Presentation and Diagnosis
- •Nonoperative Treatment
- •Balloon Dilation and Endoscopic Options
- •Stents
- •Operative Treatment
- •Reoperative Surgery
- •Anastomotic Revision and Diverting Stomas
- •New Technology
- •Conclusion
- •To Avoid Anastomotic Strictures in Colorectal Resections
- •Five Points on Diagnosing and Managing Anastomotic Strictures
- •References
- •Intraoperative Ureteral Injury
- •Introduction
- •Role of Preoperative Stenting
- •Incidence of Ureteric Injury and Early Identification of Injury
- •Placement of Ureteral Stents
- •Detection of Ureter Injury
- •Management of Ureter Injury
- •Proximal Third Injuries
- •Middle Third Ureteral Injuries
- •Lower Third Ureteral Injuries
- •Delayed Ureteral Transection or Ligation
- •Management Post Repair
- •Outcomes
- •Key Points to Avoiding Injury
- •Key Points to Diagnosis and Manage the Complication
- •References
- •Introduction
- •Anatomy
- •Incidence
- •Types of Prostatic Urethral Injury
- •Prevention
- •Detection
- •Management
- •Delayed Rectourethral Fistula
- •Conclusion
- •Key Points on Avoiding Complications
- •Key Points on Diagnosing/Managing Prostatic Urethral Injuries
- •References
- •Vaginal Injury During Stapled Anastomosis
- •Introduction
- •How to Avoid Vaginal Injury
- •How to Fix Vaginal Injury
- •Key Points on How to Avoid Vaginal Injury
- •Management of Rectovaginal Fistula
- •Introduction
- •General Principles
- •Local Repair
- •Mucosal Advancement Flap Repair
- •Endorectal Advancement Flap with Muscular Plication (Anterior Levatorplasty)
- •Transanal Sleeve Advancement Flap
- •Transvaginal Repair
- •Fistulotomy
- •Ligation of Intersphincteric FistulaTract
- •Biological Agents: Fibrin Glue and Fistula Plug
- •Miscellaneous
- •Tissue Transfer Procedures
- •Gracilis Muscle Interposition Flap
- •Martius Flap
- •Abdominal Procedure
- •Transperineal Omental Flap
- •Perioperative Management
- •Conclusion
- •Key Points to Avoid Complications
- •Key Points on Diagnosis and/or Managing Complications
- •References
- •Management of Presacral/Pelvic Bleeding
- •Introduction
- •Anatomy
- •Patterns of Injury
- •Management
- •Role of the Anaesthesiologist
- •Role of the Surgeon
- •Minimal-Access Surgery
- •The Postoperative Period
- •Summary
- •Key Points
- •References
- •Introduction
- •Preoperative Evaluation
- •Medical Comorbidities
- •Radiation Therapy
- •Chemotherapy
- •Imaging
- •Timing of Reconstruction
- •Classification of Defect
- •Reconstructive Surgical Tenants
- •Adjuncts to Flap Surgery
- •Negative Pressure Wound Therapy
- •Tissue Expansion
- •Biologic Tissue Matrices
- •Rectus Abdominis Muscle
- •Gracilis Muscle Flap
- •Gluteus Maximus Muscle
- •Pudendal Flap
- •Anteriolateral Thigh Flap
- •Postoperative Care
- •Ambulation
- •Drain Management
- •Complications
- •Summary
- •Key Points: Preventing Complications
- •Key Points: Managing Complications
- •References
- •Complications After TEM (Transanal Endoscopic Microsurgery) and TAMIS (Transanal Minimally Invasive Surgery)
- •Background
- •Complications of TEM and TAMIS
- •Postoperative Fever
- •Wound Dehiscence
- •Rectal Pain
- •Peritoneal Perforation
- •Pelvic Phlegmon and Abscess
- •Fistula
- •Bleeding
- •Incontinence
- •Conclusion
- •Key Points: Avoiding a Complication
- •Key Points: Managing/Diagnosing Septic Complications
- •References
- •Parastomal Hernia
- •Overview
- •Definition and Classification
- •Incidence
- •Pathophysiology
- •Risk Factors
- •Complications
- •Prevention
- •Preoperative Considerations
- •Operative Considerations
- •Diagnosis
- •History and Physical Exam
- •Imaging
- •Management
- •Nonoperative Management
- •Operative Management
- •Open Approach
- •Laparoscopic Approach
- •Postoperative Complications
- •Management of Recurrent Parastomal Hernias
- •Key Points: Diagnosing/Managing Parastomal Hernia
- •Key Points: Avoiding Parastomal Hernia Complications
- •References
- •Stoma Retraction/Ischemia/Stenosis
- •Introduction
- •Etiology/Incidence/Risk Factors
- •Prevention
- •Recognition/Assessment/Severity/Therapy
- •Conclusions
- •Five Keys Points in Diagnosing and Managing Stenosis, Retraction, and Ischemia in an Ostomy
- •Five Key Points on How to Avoid Tension and Ischemia in an Ostomy
- •References
- •Incontinence After Lateral Internal Sphincterotomy/Fistulotomy
- •Introduction
- •Lateral Internal Sphincterotomy
- •Fistulotomy
- •Management
- •Evaluation
- •Treatment
- •Injectables
- •Magnetic Bowel Sphincter
- •Sacral Nerve Stimulator
- •Artificial Bowel Sphincter
- •Diversion
- •Key Points: Strategies to Avoid the Complication of Incontinence
- •Key Points: Diagnosing and/or Managing the Complication of Incontinence Either Intraoperatively or Postoperatively
- •References
- •Anal Stenosis After Hemorrhoidectomy: Avoidance and Management
- •Introduction
- •Diagnosis
- •Classification of Stenosis
- •Treatment
- •Prevention
- •Nonoperative Intervention
- •Operative Intervention
- •Anatomic Versus Functional Stenoses
- •Preoperative Planning
- •Postoperative Care
- •Summary
- •Key Points: Managing Complications
- •References
- •Part V
- •Other Considerations
- •Delivering Bad News: Conversations with My Surgeon
- •Introduction
- •Informed Consent
- •The Family Does Not Want the Patient to be Fully Informed
- •Perioperative Death
- •When an Intraoperative Death Does Occur
- •Discussion of Unresectability or Metastatic Disease that Precludes Resection
- •Discussion of a Postoperative Complication
- •Discussion of the Unanticipated Major Postoperative Complication
- •Discussion of Operative Findings
- •The Need for Reoperation
- •Complications that Occur in your Absence from the Hospital
- •Withdrawal of Life-Sustaining Measures
- •Discussing the Pathology Report
- •Discussion of Long-term Survival Prospect
- •Management of the Difficult Family
- •References
- •Index

36934 Intraoperative Ureteral Injury
anastomotic leak is demonstrated. A urinary leak
occurs in approximately 10–24 % of ureteroureterostomy repairs. Most early postoperative leaks
can be managed with continued closed-suction
drainage.
Outcomes
Recognition and treatment of ureteric injuries at
the time of surgery are associated with less morbidity compared to those in whom the diagnosis
was delayed. In patients with prompt diagnosis
of ureteric injury, Al-Awadi et
al. demonstrated
a 94 % successful resolution of ureteric injuries
[18
]. The success rate for a ureteroureterostomy
%. Between 10 and 24 % of early repairs
is 90
develop a urine leak, which is managed with
the drain
stricture develops in approximately 10
teroureterostomy
placed intraoperatively [18]. A ureteral
% of ure-
repairs. Ureteral strictures are
late complications and can be managed endoscopically with balloon dilation. If endoscopic
management is unsuccessful, then open repair
is required. Ileal replacement of the ureter has a
reported success rate of 83–100
% [26]. Armatys
et al. reported a 3 % anastomotic stricture and 6 %
fistula rate after
ileal replacement [26]. Ileal replacement of the ureter can result in hyperchloremic metabolic acidosis, which can be treated by
sodium bicarbonate. Pisters et
that the overall success rate of a
al. demonstrated
TUU, measured
in terms of patent anastomosis and bilateral functioning kidneys, is greater than 95
Psoas
hitch and Boari flap have also been
% [24].
shown to be highly successful. Long-term success rates have been reported from 95 to 100
[5, 6
, 18, 22]. Ureteral reflux typically does not
%
lead to long-term complications. Obstruction at
the reimplantation site has been reported in ap-
proximately 5−10
%, which is
typically managed
with endoscopic dilation [5, 6, 18, 22].
Key Points to Avoiding Injury
1. Knowledge of the ureter anatomy is essential
to avoid injury.
2. Preoperative imaging should be reviewed to
determine the anatomy of the ureter and the
possibility of the ureter being involved by
tumor.
3. Prophylatic ureteral stents should be placed in
high-risk patients.
4. The ureter should be identified with meticulous dissection early in the procedure.
5.
Visualization of the
ureter must be performed
before transection of colonic mesentery.
Key Points to Diagnosis and Manage the Complication
1. Lower ureteral injuries are the most common
injuries and should be managed with ureteral
reimplantation to the bladder. Avoid primary
ureteroureterostomy for lower ureteral injures.
2. If an injury is suspected intraoperatively, indigo carmine can be given intravenously and
the ureter observed for extravasation of dye.
3. If an injury is detected intraoperatively, the
ureter should be debrided to healthy tissue and
a spatulated tension-free anastomosis should
be performed if possible. The type of repair
depends on the site and type of injury.
4. If an injury is suspected postoperatively, the
BUN and Cr of an intra-abdominal fluid collection or drain fluid can be compared to the
patient’s serum level.
5. A retrograde pyelogram can give the precise
location of injury, and a stent could be deployed over the injury.
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re-

ProstaticUrethral Injury
Negar M. Salehomoum and Steven D. Wexner
35
Introduction
Colorectal surgery frequently involves pelvic dissection for both benign and malignant conditions.
While the ureter is more commonly injured during pelvic surgery, the urethra is not immune [1].
The most common urethral injury in colorectal
surgery is secondary to traumatic Foley catheter
placement. We herein discuss prostatic urethral
injuries, specifically offering tips on prevention, methods of detection, and management of
injuries.
Anatomy
An important factor to help reduce the risk of
prostatic urethral injuries is a thorough understanding of its anatomy. The urethra can be anatomically divided into an anterior and posterior
portion, separated by the genitourinary perineal
membrane.
The anterior urethra, also known as the
spongy or cavernous urethra, consists of the bulbous portion and pendulous, or penile, portion.
The bulbous portion starts at the genitourinary
perineal membrane and extends to the penoscrotal junction where the pendulous portion begins
S. D. Wexner () · N. M. Salehomoum
Department of Colorectal Surgery, Cleveland Clinic
Florida, 2950 Cleveland Clinic Blvd,
Weston, FL 33331, USA
e-mail: wexners@ccf.org
and extends to the external meatus. Figure 35.1
illustrates this anatomy.
The posterior urethra is composed of the prostatic urethra and the membranous, or intermediate, portion of the urethra. The prostatic urethra is
the first portion of the urethra leading to the intermediate portion which is enclosed by the sphincter urethrae muscle. While the membranous portion of the posterior urethra is most commonly
injured secondary to pelvic fractures, the prostatic segment of the posterior urethra is susceptible
to iatrogenic injury [2]. The majority of prostatic
urethral injuries are secondary to prostatic resections such as transurethral prostatic resections
(TURP) or radical prostatectomies. Figure 35.2
demonstrates the close relation between the prostatic urethra and rectum, which makes it susceptible to iatrogenic injury during pelvic surgery.
The discussion within this chapter is limited to
injuries of the prostatic urethra which can occur
during colorectal surgeries.
Incidence
Colorectal operations at risk for injuring the urethra include proctectomies and abdominoperineal resections. Such injuries may occur during
dissection for either benign or malignant conditions. This fact is not surprising considering that
the anterior portion of the lower rectum is intimately associated with the posterior border of the
prostate.
T. M. Pawlik et al. (eds.), Gastrointestinal Surgery, DOI 10.1007/978-1-4939-2223-9_35,
© Springer Science+Business Media New York 2015
371

372 N. M. Salehomoum and S. D. Wexner
Fig. 35.1 The anterior and posterior portions of the urethra are depicted
Types of Prostatic Urethral Injury
During pelvic surgery and dissection of the rectum, the prostatic urethra is prone to two different
types of injury. Transection of the urethra during
sharp dissection may lead to immediate urine
leakage although transection with an energy device may temporarily occlude the lumen resulting in a delayed leak. Pelvic dissection with elec-
trocautery may lead to ischemia of the urethra
followed either by a stricture or a delayed leak.
Prevention
The key to preventing a prostatic urethral injury, or
any urinary injury for that matter, is to be vigilant
about the risk. This risk is increased in patients

37335 Prostatic Urethral Injury
Fig. 35.2 Demonstration of the anatomy of the urethra
in relation to the rectum. The straight arrow points to the
rectum. The wavy arrow points to the prostatic urethra
with bulky anterior rectal tumors, a history of
radiation, and/or history of a prostatectomy, all
of which may obliterate the rectoprostatic space.
The inflammation and scar tissue in the former
setting make it difficult to visualize and dissect in
the plane immediately anterior to the rectoprostatic, or Denonvillier’s fascia. The large inflamed
rectum in patients with proctitis and following
an anastomotic leak also increases the risk of
injury.
One technique to facilitate awareness of the
location of the urethra is the placement of a large
diameter Foley catheter. Alternatively, urethral
sounds may be more easily palpated intraoperatively secondary to their rigidity. The wider
diameter catheter can help the surgeon palpate
the prostatic urethra especially when nearing it.
However, it is important to not have an overwhelming sense of security with this technique
as it may still be difficult to identify the location of the urethra in cases of previous radiation
and/or prostatectomy. When reoperating on patients following a pelvic anastomotic leak or for
a recurrent rectal carcinoma, special vigilance is
needed.
Detection
Should the surgeon encounter the unfortunate
situation of having injured the prostatic urethra,
the ideal time for detecting the injury is during
surgery. Early recognition may allow for synchronous repair and may potentially allow for a
better repair without having to subsequently reenter the pelvis.
Some surgeons advocate the routine use of indigo carmine or methylene blue during colorectal
surgeries in which the urinary system is at risk.
Therefore, if the surgeon is concerned about the
prostatic urethra, such as in cases where bulky
tumors or radiation have eliminated the normal
planes, the anesthesiologist can administer 10 mL
of indigo carmine or methylene blue intravenously with or without furosemide to expedite diuresis. Another intraoperative method for detecting
injuries is to inject 10–20 ml of methylene blue
via an angiocatheter placed in the urethra adjacent to the Foley catheter [1]. Again, any visualized extravasation of methylene blue would indicate injury to the urinary tract.
The surgeon may also encounter delayed recognition of urethral injury. Postoperative signs of
urinary injury may include a rise in blood urea
nitrogen (BUN) and creatinine levels secondary
to urinary absorption from the peritoneal cavity and an increase in drain output, particularly
if serous in quality. If an injury is suspected, the
drain output can be sent to the laboratory for a
creatinine level. A drain creatinine level in excess
of the serum creatinine level indicates a urinary
leak. A renal ultrasound may indicate dilatation of the more proximal urinary system or a
distended bladder if the urethra is strictured. A
computed tomography scan of the abdomen and
pelvis with intravenous contrast may also be used
to detect urinary injuries; however, the contrast
must have reached the site of injury for extravasation to occur and will not indicate the specific
site of injury.
A retrograde urethrogram can also be used to
visualize urethral injuries, either intraoperatively
or postoperatively. Rosenstein and Alsikafi have

374 N. M. Salehomoum and S. D. Wexner
provided a detailed description the technical
aspects of performing a retrograde urethrogram
[3]. The patient is first positioned supine on the
table, and then the left pelvis is elevated 30–45°
from the table. The right thigh is bent at a right
angle to the hip while the left leg is kept straight.
A 14 French Foley catheter is then inserted into
the tip of the penis and the Foley balloon distended with 2 ml of water; 30 ml of water-soluble
contrast is then injected and a radiograph exposure taken at least near the end of the injection if
not throughout the injection. This technique will
allow appropriate visualization of the entire urethra and any leaks or strictures.
Management
A prostatic urethral injury detected at any time
should lead to a urology consultation if available
and primary repair at the initial operation. It is
important to keep in mind that most data regarding the management and outcome of prostatic
urethral injuries are based on traumatic urethral
disruptions.
Intraoperative detection of a prostatic urethral injury will potentially allow for a primary
repair if able to be performed in a tension-free
manner [1]. The two ends of the urethra should
be spatulated in such a repair to try to obviate
subsequent anastomotic stricture. In patients who
have undergone pelvic radiation, it may be prudent to reinforce the repair with omentum, a local
tissue flap, and/or a biologic mesh [1]. In cases
of significant loss of urethra, urethral reconstruction has been described using a pedicled gracilis
flap [4]. During intraoperative repair of the urethra, if there is difficulty in identifying the more
proximal urethra after a complete transection, a
urethral sound may be placed through either a
suprapubic location or by creating an anterior
cystotomy.
Prostatic urethral injuries that are detected
postoperatively are more difficult to manage. Unless a patient is within the first few postoperative
days, there will likely be significant adhesions
in the pelvis making any immediate surgical approach more difficult. Experience with traumatic
posterior urethral injuries indicates that primary
urethral realignment results in lower rates of
fibrotic defects compared to primary bladder
drainage with plans for delayed urethroplasty;
however, the erectile dysfunction and urinary incontinence rates were higher [5–7]. Other authors
have reported lower rates of erectile dysfunction
and urinary incontinence following surgical realignment [8–10]. Primary urethral realignment
can be performed either surgically, transabdominal or transperineal, or endoscopically. A
urethral stricture, either from cautery injury or
following initial management of the injury with
primary urethral realignment, may be amenable
to bulboprostatic anastomotic urethroplasty via
either an abdominoperineal or transperineal approach [11–13]. It is important to keep in mind
that some degree of the complications described
with the various techniques may be related to the
traumatic mechanism of injury.
The key to managing any urinary injury is to
allow adequate drainage of the urinary system. A
bladder catheter should be kept in place across
the urethral injury postoperatively to keep the
bladder decompressed. Some authors also advocate placing a suprapubic catheter in addition to
the bladder catheter to ensure appropriate drainage should one mechanism fail. If, however, the
urethral injury is postoperatively detected, a suprapubic catheter should be placed for drainage.
Additionally, drains placed adjacent to any of
the above-discussed repairs will enable detection
of urinary extravasation and, more importantly,
help ensure adequate drainage should a urine leak
or a fistula develop.
Delayed Rectourethral Fistula
A delayed urethral injury may also present as a
rectourethral fistula. These patients may present with pneumaturia, fecaluria, urine draining
through the rectum, or recurrent urinary tract
infections. Different modes of treatment exist in
the treatment of delayed iatrogenic rectourethral
fistulas including transperineal, transanal, transsphincteric, and transabdominal approaches [14].

37535 Prostatic Urethral Injury
Transperineal repairs usually involve closure of the rectum and/or closure of the urethral
opening. These outcomes are improved by interposing muscle between the rectal and urethral
repairs, especially if the pelvis was previously
irradiated. The gracilis muscle and dartos muscle interposition flaps are well described in the
treatment of rectourethral fistulas [15–18]. The
preference of the authors is to perform gracilis interposition flaps for pelvic fistula disease specifically using the transperineal approach because it
provides great access to the fistula, brings a large
piece of viable muscle to help buttress the fistula
repair, and minimally affects the donor extremity
with mild numbness being the main side effect
[16, 19–21]. The gracilis muscle is a large muscle
dependent on one main neurovascular bundle at
its origin, which makes it versatile. All patients
should undergo fecal diversion either prior to
or occasionally at the time of graciloplasty. The
creation of an ileostomy or colostomy should facilitate healing by reducing fecal contamination.
Maintenance of an indwelling Foley catheter and
occasionally also a suprapubic catheter throughout the duration of treatment is mandatory. The
objective is to prevent both urine and stool from
entering the area of the repair.
The technical aspects of performing a graciloplasty have been well described [19]. The gracilis
muscle is harvested from the patient in the LloydDavies position. A 3–4-cm incision is first made
in the distal medial thigh, staying posterior to the
saphenous vein. Dissection is carried down onto
the gracilis muscle after which its tendon is encircled with either a red rubber catheter or a penrose drain. A second small incision is then made
on the proximal thigh about four fingerbreadths
distal to the pubic tubercle where the gracilis
muscle is again identified and encircled. The surgeon then bluntly dissects through the space superficial to the gracilis muscle to create a tunnel
connecting both incisions. The gracilis tendon
is then divided from behind the medial condyle
after which a laparoscopic energy device is used
to circumferentially mobilize the muscle up to its
neurovascular bundle 10
cm from the
pubic tubercle. Throughout this procedure, it is important
for the anesthesia team to avoid any paralytics
so that the location of the neurovascular pedicle
Fig. 35.3 The patient is in the prone jackknife position.
The gracilis muscle is grasped and about to be pulled into
the perineal incision
can be confirmed by stimulating the nerve. A
tunnel is then created from the upper thigh incision to the site of the planned perineal incision.
The thigh incisions are closed over a drain. The
patient is then routinely repositioned into the
prone jackknife position to optimize exposure. A
5-cm circumanal perineal incision is then made
through the perineal body and carried proximally
at least 2
cm above the fistula in healthy
tissue.
The edges of the fistula tract are then resected.
While the rectal defect is always closed with an
advancement flap, the urethral defect is almost
always left open depending on the fistula size
and on the condition of the surrounding tissues;
very small urethral defects surrounded by healthy
pliable tissue may occasionally be primarily repaired. A series of bilateral 2.0 prolene sutures
are placed from the apex to the distal aspect of
the dissected space, after which the sutures are
passed through the gracilis muscle, interposing
it between the rectum and urethra (Figs.
35.4
and 35.5). A closed suction drain is also left
35.3,
under the perineal incision. Later, the patient is
placed in an adduction splint prior to reversal of
general anesthesia.
Postoperatively, the patient is on bed rest with
an adductor splint for 3
days, intravenous antibiotics for 3 days after which oral antibiotics are
started, and a bladder catheter
for 6–8
weeks.
Successful fistula closure is verified 6 weeks
following surgery with a water
-soluble contrast
enema, a retrograde urethrogram, cystoscopy,

376 N. M. Salehomoum and S. D. Wexner
Fig. 35.4 The gracilis muscle after being pulled through
the perineal incision. (With permission from Zmora et al.
[15] © by Lippincott Williams & Wilkins)
and examination under anesthesia. Stoma closure is generally performed 12 weeks after the
surgery, at which time the Foley catheter is also
removed.
We reviewed our results with gracilis interposition flaps for rectourethral, rectovaginal, and
pouch-vaginal fistulas [16]. Our results included
53 patients from 1995 to 2007 including 36 males
with a rectourethral fistula and 17 females, 15 of
whom had a rectovaginal fistula. Thirty of the 36
males had undergone treatment for prostate carcinoma. Five males required a second gracilis interposition flap for the following reasons: failure
after an initial gracilis flap, intraoperative muscle
necrosis, perineal sepsis requiring debridement,
and persistent fistula. Only one of those males
had a persistent fistula after two gracilis flaps;
however, he eventually healed his fistula after a
transanal rectal advancement flap. There were
23 complications in 17 patients: perineal wound
infection, urethral stricture, prolonged perineal
wound drainage, fever, urinary retention, urinary
tract infection, perineal bleeding, penile cellulitis,
deep venous thrombosis, thigh hematoma, thigh
pain/numbness, and fecal incontinence following
stoma reversal. Thus, our success rates were 78 %
after initial graciloplasty and 97 % after secondary
procedures. Table 35.1 includes a review of the
success rates with graciloplasty in treating rectourethral fistulas.
Fig. 35.5 The gracilis muscle being interposed between
the rectum and urethra. (With permission from:Zmora
al. [15] © by Lippincott
et
Williams & Wilkins)
Transanal techniques involve a full-thickness
rectal advancement flap beyond the area of the
fistula with simultaneous ligation of the fistula
tract. Visualization for more proximal rectourethral fistulas has been augmented with the availability of transanal endoscopic surgery (TES).
Transanal endoscopic surgery includes transanal
endoscopic microsurgery (TEM) during which a
large rigid anoscope is placed in the anus with
subsequent insufflation of the rectum to allow
visualization. Other variations of TES include
placing a single-incision laparoscopic gel port
into the anus with subsequent insufflation. The
TES platforms present much improved visualization than standard transanal surgery. Full-thickness rectal advancement flaps with ligation of the
fistula have been reported using TEM [22, 23].
A urethral stent may also be placed to span the
fistula opening without primary closure of the
urethral end with success [22].
A transsphincteric approach most commonly
involves a posterior, or York-Mason, incision extending from the anal verge to the coccyx with
division of the sphincter muscles as well as the
posterior rectal wall [24–28]. The fistula tracts
may then be either excised or ligated. This procedure has the risk of rectocutaneous or anocutaneous fistula and fecal incontinence and may not be
the best option in patients at risk for poor wound
healing.

Table 35.1 Review of gracilis interposition for repair of rectourethral fistula
Study Year Patients with
Samalavicius et al. [31] 2012 1
Netsch et al. [32] 201
Samplaski et al. [33] 201
Gonzalez-Contreras [34] 201
Vanni et al. [35
Ulrich et
Gupta et al. [37] 2008 15 0 (0) 100 100
Wexner et al. [16] 2008 36 18 (50) 78 97
Rabau et al. [38] 2006 4 0 (0) 75–100
Bukowski et al. [39] 1995 1 0 (0) 0 100
RUF rectourethral fistula
a
Exact success rate could not be determined. These papers evaluated both rectourethral and rectovaginal fistulas, but
it is unclear to which group the persistent fistula(s) belong.
] 2010 68 36 (53) 87 100
al. [36] 2009
gracilis interposition for RUF, n
1 1
1 13
1 1
26 14 (54) >
Irradiated
patients,n (%)
1 (100) 100 100
0 (0) 100 100
7 (54) 92 100
1(100) 100 100
Success rate
after initial
gracilis interposition (%)
a
94
Final success rate
(either repeat gracilis interposition or
other fistula repair)
(%)
> 94
a
75–100
a
a
37735 Prostatic Urethral Injury
A transabdominal approach will allow repair of a rectourethral fistula if a proctectomy
or prostatectomy is attempted [29, 30]. Open
or laparoscopic approaches may be undertaken.
Most transabdominal approaches described in the
literature refer to radiotherapy-induced rectourethral fistulas rather than postoperative iatrogenic
rectourethral fistulas.
This brief description of rectourethral fistula
repairs sheds light to the numerous techniques
that exist. It is important to individualize treatment options depending on the patient’s comorbidities, expectations, and quality of life, in addition to the anatomic details of the fistula.
Conclusion
Prostatic urethral injury is a major risk of pelvic
colorectal surgery, especially when involving
reoperative surgery, irradiated tissue, bulky tumors, and obese males. Avoiding urethral injury
requires a high awareness of the risk as well as
prophylactic measures to try to reduce the risk.
Such techniques include the use of a large urethral catheter or sound to palpate the urethra.
Suspicion for injury can be intraoperatively
tested with retrograde instillation of indigo carmine, methylene blue, and/or a retrograde urethrogram. Furthermore, retrograde urethography
remains important both during and after surgery
to diagnose the injury. In the unfortunate event
of a prostatic urethral injury, a urology consult
is highly recommended at the time of diagnosis
for optimal management. A delayed rectourethral
fistula may be treated by either a transperineal
approach with a gracilis or dartos interposition
flap or a transanal approach with a full-thickness
rectal advancement flap.
Key Points on Avoiding Complications
1. Always be aware of the possibility of urinary
injuries.
2. Be especially vigilant in cases of bulky tumors
or history of pelvic irradiation.
3. Use a large Foley catheter to palpate the urethra.
4. Insert a urethral sound to palpate the urethra.
5. If concerned about a urinary injury, check
prior to leaving the operating room.
Key Points on Diagnosing/Managing Prostatic Urethral Injuries
1. Inject methylene blue or indigo carmine either
intravenously or retrograde through the urethra to check for a urethral injury.

378 N. M. Salehomoum and S. D. Wexner
12.
2. If a urethral injury is diagnosed intraoperatively, aim to repair the injury at the initial
surgery.
3. Obtain a urology consult at time of diagnosing
a urinary injury.
4. Retrograde urethrography will best diagnose a
urethral injury either intraoperatively or postoperatively.
5.
With any urinary injury, the urine should be
diverted with either a Foley catheter or a suprapubic catheter until the injury has healed.
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