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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5535_Библиотеки_им_академика_М_И_Перельмана.pdf
1356
Medical Laboratory Technology: Volume 3
Substance Determined Drugs Causing Increased Values
False Positives
Pyramidon
Sodium bicarbonate
Sulphadiazine
Sulphamethizole
Sulphamethoxazole
Sulphapyridine
Sulphathiazole
Sulfisoxazole
Sulphonamides
Tetracycline
Thoradex
Vanillylmandelic acid
(VMA)
Aminosalicylic acid (PAS) Aspirin
Anileridine Chlorpromazine
Aspirin
BSP Guanethidine
Cough medicines (some) Imipramine
Disulfiram (Antabuse) Levodopa
Epinephrine (Adrenaline) Monoamine oxidase inhibitors
Foods and beverages (bananas,
chocolate, coffee, tea vanilla
extract)
Glyceryl guaiacolate
Insulin (large doses)
Levodopa (L-dopa)
Lithium carbonate
Mandelamine
Mephenesin
Methocarbamol
Methyldopa
Morphine
Nalidixic acid
Nitroglycerin
Norepinephrine
Oxytetracycline
Phenazopyridine
Drugs Causing Decreased Values
False Negatives
Morphine
Pentobarbital
Reserpine
Contd.
Appendices
1357
Substance Determined Drugs Causing Increased Values
False Positives
PSP
Reserpine
Salicylates
Stibophen
Xylose excretion Glucose
Phenazopyridine
Drugs thAt mAy Affect colour of urine
Colour of Urine Drug
Reddish brown Aminopyrine
Cascara and senna laxatives in acid urine
Orange Aminopyrine
Phenazopyridine
Orange to orange red Ethoxazine
Phenindione
Pyridium
Rifampin
Senna
Orange to purple red Chlorzoxazone
Orange yellow Anisindione
Fluorescein (after IV administration)
Phenindione
SalicylazoSulphapyridine (in alkaline urine)
Rust yellow to brownish Primaquine
Nitrofurantoins
Salicylazosulphapyridine
Sulphonamides
Pink to red or red brown Danthron
Dilantin
Doxidan
Phenolphthalein
Phenothiazine
Phensuximide
Magenta Phenolphthalein
Red Amidopyrine
Aniline dyes
Drugs Causing Decreased Values
False Negatives
Contd.
1358
Colour of Urine Drug
Purple red Chlordiazepoxide Ibuprofen (also pink, red)
Dark brown Phenolic drugs
Brown black Amitriptyline
Pink to brown Phenothiazine tranquillizers
Pale blue Dyrenium (Triamterene)
Reddish iron chelate Deferoxamine
Dark coloured Iron salts
Urine that darkens on standing Antiparkinson drugs
Blue or green Methylene blue
Bright yellow Riboflavin
Yellow/pink-alkaline brown Cascara
Red brown Cinchophen
Brown, green, blue Nitrofurans
Pink red Diphenylhydantoin
Dark green Phenylsalicylate
Medical Laboratory Technology: Volume 3
Desferal
Neotropin
Phenolphthalein and pyridium in acid urine
Prontosil
PSP and BSP dyes in alkaline urine
Pyridium
Phenolphthalein in alkaline urine
Phenylhydrazine
Cascara
Jecotofir
Methylene blue
Pyridium (in alkaline urine)
Riboflavin
Levodopa
Sinemet
Amitriptyline
Triamterene
Pyridium in alkaline urine
Chloroquine
Iron salts
Metronidazole
Sulphamethoxazole
Sulphonamides (some)
Phenacetin
Appendices
Drugs Affecting results of fAecAl stuDies
Drugs Affecting Faecal Studies
1359
Substance Determined Drugs Causing Increased Values
False Positives
Occult blood-benzidine
or guaiac test
Boric acid (toxicity) Ascorbic acid (high doses)
Bromides Colchicine (toxicity)
Iodides
Iodine
Iron (inorganic)
Oxidising agents (excreted in urine)
Pyridium
Drugs Causing Decreased
Values False Negatives
Drugs Affecting colour or fAeces
Colour of Stool Drug
Whitish discolouration or speckling Aluminium hydroxide, antacids
Pink or red to black Anticoagulants (excess dose)
Salicylates (causing internal bleeding)
Black Bismuth salts, iron salts, charcoal
Brownish staining Dihydroxyanthraquinones
Green to blue Dithiazanine
Green Mercurous chloride, indomethacin, calomel
Orange red Phenazopyridine
Red Phenolphthalein, pyruvium pamoate, tetracyclines in
syrup, bromsulphalein
Yellow Rhubarb, santonin
Yellow to brown Senna
Pink to red to black (resulting from internal
bleeding)
Light Sitosterols
Salicylates
Drugs Affecting results of hAemAtologic AnD serologic stuDies
Substance Determined Drugs Causing Increased Values
False Positives
Bleeding Acetylsalicylic acid
Dextran
Mithramycin
Pantothenyl alcohol and derivatives
Drugs Causing Decreased
Values False Negatives
Contd.
1360
Medical Laboratory Technology: Volume 3
Substance Determined Drugs Causing Increased Values
False Positives
Streptokinase-streptodornase
Coagulation time All causes of positive Corticosteroids
Coombs' test Epinephrine
Anticoagulants
Azathioprine
Carbenicillin (high doses in
impaired renal function)
Cephalexin
Cephaloglycin
Cephaloridine
Cephalothin
Chlorpromazine
Diphenylhydantoin
Dipyrone
Ethosuximide
Hydralazine
Isoniazid
Levodopa
Mefenamic acid
Mephalan
Methyldopa (effect lasts 6 mo)
Mithramycin
Oxyphenisatin
Penicillin
Procainamide
Quinidine
Rifampin
Streptomycin
Sulphonamides
Tetracyclines
Erythrocyte count or haemoglobin Gentamicin Acetaminophen
Methyldopa (Aldomet) Acetophenazine maleate
Drugs Causing Decreased
Values False Negatives
Acetophenetidin
Aminosalicylic acid
Amphotericin B
Antimony compounds
Antineoplastic agents
Azathioprine
Contd.
Appendices
1361
Substance Determined Drugs Causing Increased Values
False Positives
Erythrocyte count or haemoglobin Oxyphenbutazone
Drugs Causing Decreased
Values False Negatives
Fluorouracil
Floxuridine
Hydroxyurea
Mechlorethamine
Mithramycin
Triethylene-melamine
Urethane
Arsenicals
Carbamazepine
Chloramphenicol
Chloroquine
Diiodohydroxyquin
Doxapram
Ethosuximide
Furazolidone
GlucoSulphone
Haloperidol
Hydantoin derivatives
Hydralazine
Hydroxychloroquine
Sulphate
Indomethacin
Isoniazid (rare)
MAO inhibitors
Mefenamic acid
Mepacrine (quinacrine)
Mephenoxalone
Mercurial diuretics
(prolonged use)
Metaxalone
Methaqualone
Methsuximide
Methyldopa (Aldomet)
Nitrites (rare)
Novobiocin
Oleandomycin
Paramethadione,
trimethadione
Contd.
1362
Medical Laboratory Technology: Volume 3
Substance Determined Drugs Causing Increased Values
False Positives
Leukocytes Allopurinol (hypersensitivity) Acetaminophen
Aminosalicylic acid Acetophenetidin
Ampicillin Allopurinol (hypersensitivity)
Atropine (in children)
Barbiturates Aminoglutethimide
Capreomycin
Cardiotonic glycosides Aminopyrine
Cephalothin Aminosalicylic acid
Drugs Causing Decreased
Values False Negatives
Penicillamine
Penicillin
Phenacemide
Phenobarbital (rare)
Phenylbutazone
Phytonadione (large doses in
infants)
Primaquine
Primidone
Pyrazolone derivatives
Pyrimethamine
Radioactive agents (large
doses)
Rifampin
Spectinomycin
Sulphameter
Sulphonamides (rarely with
Sulphathiazole)
Sulphones
Sulphonylureas (oral
hypoglycemic agents)
Tetracycline
Thiazide diuretics (rare)
Thiocyanates
Thiosemicarbazones
Trimethadione
Tripelennamine
Troleandomycin
Vitamin A (excess dose and
use)
Acetohexamide
Contd.
Appendices
1363
Substance Determined Drugs Causing Increased Values
False Positives
Chlorpropamide Amodiaquine
Clindamycin Antineoplastic agents
Cloxacillin Chlorambucil
Desipramine, imiprazine Cyclophosphamide
Diethylcarbamacine Fluorouracil
Digitalis (rare) Hydroxyurea
Diphenhydramine Mechlorethamine
Dipyrone Mithramycin
Epinephrine Triethylenemelamine
Erythromycin
Florantyrone (in patients with preexisting liver disease)
Antipyrine
Gold compounds Carbimazole
Hydantoin derivatives Cephalothin
Iodides Chloramphenicol
Iron dextran injection (Imferon) Chlordiazepoxide
Isoniazid Chlorpropamide
Kanamycin Chlorprothixene
Lincomycin (one case reported) Chlorthalidone
Methicillin Clofibrate
Methyldopa Cloxacillin
Methysergide Colistin
Nalidixic acid Corticosteroids reported for
Novobiocin
Phenothiazines (large doses)
Potassium iodide Diazepam
Primaquine Dichlorphenamide
Procainamide Diethazine
Drugs Causing Decreased
Values False Negatives
Cytoxan
Floxuridine
Azathioprine
Bismuth
Carbamazepine
Chloroquine
Clindamycin
prednisolone; Prednisone)
Desipramine, imipramine
Contd.
1364
Medical Laboratory Technology: Volume 3
Substance Determined Drugs Causing Increased Values
False Positives
Streptodornase streptokinase Diiodohydroxyquin
Ristocetin Diphenhydramine
Streptomycin Doxapram
Stibocapate (antimony) Ethacrynic acid
Sulphonamides (long-acting) Furosemide
Tetracyclines (prolonged use) GlucoSulphone
Triamterene Griseofulvin
Trifluperidol Haloperidol
Vancomycin Hydantoin derivatives
Viomycin
Drugs Causing Decreased
Values False Negatives
Ethoxazolamide
Glaucarubin
Gold compounds
Hydralazine
Hydroxychloroquine
Idoxuridine (in high
concentration)
Indandione derivatives (oral
anticoagulants)
Indomethacin
Iothiouracil
Mefenamic acid
Mepacrine (Quinacrine)
Mepazine
Mephenesin
Meprobamate
Mercurial diuretics (rare)
Metaxalone
Methampyrone
Methazolamide
Methimazole
Methocarbamol
Methsuximide
Methyldopa
Methylthiouracil
Methyprylon (metabolite:
methicillin sodium, oxacillin)
Methysergide
Metronidazole
Contd.
Appendices
1365
Substance Determined Drugs Causing Increased Values
False Positives
Drugs Causing Decreased
Values False Negatives
Monoamine oxidase
inhibitors
Nitrofurantoin (rare)
Novobiocin
Oleandomycin
Oxandrolone
Oxazepam
Oxyphenbutazone
Paraldehyde
Penicillamine
Penicillins
Phenothiazines (large doses)
Phenylbutazone
Potassium perchlorate
Primaquine
Primidone (rare)
Procainamide (both reported)
Procarbazine
Propylthiouracil
Protriptyline
Pyrathiazine (prolonged use)
Pyrazolone derivatives
Pyrimethamine (Daraprim)
Quinine
Radioactive agents
Rifampin
Ristocetin
Sulphonamides*
Sulphonylureas
(oral hypoglycemic agents)
Sulthiame
Thiabendazole
Thiazidediuretics (rare)
Thiosemicarbanzones
Thiothixene
Tripelennamine
Vitamin A (prolonged use)
Contd.