In recent years, there is a growing demand of ‘Point-of-care testing (POCT)’ that led to the rapid advancements in technology that will enable the physician to make decision on the bedside. This is making rapid changes in all aspects of health care. One of the major changes in the clinical laboratory has been the implementation and increased use of POCT. This brings the laboratory test to the patient rather than obtaining a specimen from the patient and transporting it to the laboratory for testing. This makes laboratory test results available more rapidly, providing improved patient care. In advanced countries it is applied in numerous situations—nursing homes, physician’s oce, emergency rooms, intensive care units and for bedside testing in hospital wards. The evolution of small, simple-to-use analysers that require only one drop, or less, of specimen has led to widespread POCT implementation. Handheld portable analysers can measure substances such as glucose, haemoglobin, cholesterol and electrolytes. Most require only a drop of blood, usually obtained by nger stick. Thus in the near future many of the routine clinical laboratory tests will be available in remote villages of developing countries although in the urban seing large automated system will continue to function. The clinical laboratories, however, will have to stay involved in making recommendations and compare the results with the classic procedures.