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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5881_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Aim and Scope
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •About the Editors
- •1.1 Introduction
- •1.2.1 Friction
- •1.2.1.3 Friction Under Lubricated Conditions
- •1.7.1 Joint Tribology
- •1.7.2 Skin Tribology
- •1.7.3 Oral Tribology
- •1.8 Summary
- •References
- •2.1 Introduction
- •2.3.1 Fluid Pressurization/Fluid-Film Lubrication
- •2.3.2 Boundary Lubrication
- •2.3.3 Hydrodynamic Lubrication
- •2.3.4 Squeeze-Film Lubrication
- •2.3.5 Synovial Fluid
- •2.3.6 Hydration Lubrication
- •2.5.2 Scaffolds
- •2.5.3 Synthetic Polymer
- •2.5.4 Polyacrylamide
- •2.5.5 PEG Hydrogel
- •2.5.6 PVA Hydrogel
- •2.5.7 Double Network Hydrogel
- •2.5.8 Triple Network Hydrogel
- •2.6.1 Polyacrylamide
- •2.6.2 PEG Hydrogel
- •2.6.3 PVA Hydrogel
- •2.6.4 Double Network Hydrogel
- •2.6.5 Triple Network Hydrogel
- •2.7.1 Mechanical Properties
- •2.7.2 Structural Properties
- •2.8 Conclusion
- •References
- •3.1 Introduction
- •3.3.1 Label-Based Biosensors
- •3.3.2 Label-Free Biosensors
- •3.4 Different Nanobiosensing Techniques
- •3.4.1 Optical Sensing
- •3.4.2 Electrochemical/Electrical Sensing
- •3.4.3 Magnetic Sensing
- •3.4.4 Mass-Based Sensing
- •3.6.2 Neurodegenerative Diseases
- •3.6.3 Infectious Diseases
- •3.6.4 Metabolic Diseases
- •References
- •4.1 Introduction
- •4.2.1 Surface Functionalization
- •4.2.2 Bioconjugation
- •4.3 Synthesis Approach
- •4.3.1 Hydrothermal Method
- •4.3.2 Chemical Vapor Deposition (CVD)
- •4.3.3 Wet Chemical Method
- •4.4 Plasmonic Black Bodies (PBBs)
- •4.4.1 Gold NP (AuNPs)-Based PBB
- •4.4.2 Silver NPs (Ag NPs)-Based PBB
- •4.4.3 Platinum NPs (Pt NPs)-Based PBB
- •4.5 Biomimetic NP
- •4.6 Upconverting NP (UCNP)
- •4.6.1 Synthesis
- •4.7 Inorganic NP
- •4.7.1 Synthesis
- •4.8 Photothermal Therapy (PTT)
- •4.9 Conclusion
- •References
- •5.1 Introduction
- •5.2 Human Skin
- •5.10 Future Scope
- •5.11 Conclusion
- •References
- •6.1 Introduction
- •6.1.1 Class 1
- •6.1.2 Class 2
- •6.1.3 Class 3
- •6.4.1.1 Surface Patterning
- •6.4.1.2 Direct-Write Patterning
- •6.4.1.5 Dip-Pen Nanotechnology
- •6.4.1.7 Composing Using Beams
- •6.4.1.8 Direct Write Photolithography (DWP)
- •6.4.1.9 Light-Beam Lithography Electron
- •6.4.1.10 Focused Ion Beam Lithography
- •6.4.2 Fabrication Techniques
- •6.4.2.4 Non-invasive Glucose Monitoring Devices Technique
- •6.4.2.6 Cost-Effective Electrochemical Voltametric Sensors Techniques
- •6.4.2.7 Three-Dimensional (3D) Printing Techniques
- •6.4.2.8 UV-LED Stereolithography Printer Technique
- •6.4.2.9 4D Printing Techniques
- •6.4.2.10 Advanced Biomedical Techniques Involving Biorobots
- •References
- •7.1 Introduction
- •7.6 Mechanical Biocompatibility Challenges
- •7.7 Poor Bio-Printing Resolution
- •7.9 Limited Biomaterial Selection
- •7.11 Conclusion
- •8.2 Animal Tribology
- •8.2.1 Joint
- •8.2.3 Integumentary Change
- •References
- •8.1 Introduction
- •8.3.1 Nanotribology
- •8.4 Green Tribology
- •8.5 Conclusion
- •References
- •9.1 Introduction
- •9.2 Bio-Tribological Issues
- •9.3.2 Bone Fracture Fixation
- •9.3.4 Cardiovascular Devices
- •9.3.5 Minimal Invasive Surgical Devices
- •References
- •10.1 Introduction
- •10.2.2.1 Structural Integrity
- •10.2.2.2 Controlled Release Properties
- •10.2.2.3 Enhanced Drug Loading Capacity
- •10.2.2.4 Tailored Material Properties
- •10.2.3.1 Biocompatibility
- •10.2.3.3 Mechanical Properties
- •10.2.3.4 Drug Compatibility
- •10.2.3.5 Fabrication Compatibility
- •10.3.1 Matrix Material Properties
- •10.3.4 Biocompatibility Assessment
- •10.3.4.1 In Vitro Cell Culture Studies
- •10.3.4.2 Hemocompatibility Studies
- •10.3.4.3 In Vivo Animal Studies
- •10.3.4.4 Histological Analysis
- •10.3.4.5 Immune Response Evaluation
- •10.3.4.6 Biodegradation Assessment
- •10.4 Surface Engineering Considerations
- •10.4.2.1 Surface Coatings
- •10.4.2.2 Plasma Treatment
- •10.4.2.3 Surface Grafting
- •10.4.2.4 Dip Coating
- •10.4.2.5 Spray Coating System
- •10.4.2.6 Electrotreated Coating
- •10.4.2.9 Microfabrication Techniques
- •10.4.2.10 Surface Roughness Control
- •10.5.1.2 Mechanical Properties
- •10.5.1.3 Surface Characteristics
- •10.5.1.4 Release Kinetics Analysis
- •10.5.1.5 Biological Compatibility
- •10.5.1.7 Other Analyses
- •10.6 Advanced Fabrication Techniques
- •10.8 Conclusion
- •References
- •11.1 Introduction
- •11.2 Shape Memory Alloys (SMA)
- •11.3 Shape Memory Polymers
- •11.3.1 Heat
- •11.3.2 Light
- •11.3.3 Magnetic Field
- •11.4 Shape-Changing Hydrogels
- •11.5 Biomedical Applications
- •11.6 Conclusion
- •References
- •12.1 Introduction
- •12.3 Bioresorbable Orthopedic Implants
- •12.4.1 Polylactides
- •12.4.2 Poly (Ortho Esters)
- •12.4.3 Polyphosphoesters
- •12.4.4 Polyphosphazenes
- •12.4.5 Polycaprolactone
- •12.4.6 Polyurethanes
- •12.4.7 Polycarbonates
- •12.5.1 Compression Molding
- •12.5.2 Transfer Molding
- •12.5.3 Injection Molding
- •12.5.4 Extrusion
- •12.5.5 Blow Molding
- •12.5.6 Calendering Process
- •12.5.7 Fiber Spinning
- •12.5.8 Thermoforming
- •12.5.9 Polymer Foaming
- •12.7 Challenges
- •12.8 Conclusion
- •References
- •13.1 Introduction
- •13.3.1.1 Total Hip Replacement (THR)
- •13.3.2 Resurfacing Hip Replacement (RHR)
- •13.5.1 Adhesive Wear
- •13.5.2 Abrasive Wear
- •13.5.3 Fatigue Wear
- •13.5.4 Corrosion/Oxidative Wear
- •13.5.5 Surface Cracking
- •13.6.1 Metallic Implants
- •13.6.1.1 Stainless Steel
- •13.6.1.2 Co-Cr Alloys
- •13.6.1.3 Ti-Alloy
- •13.6.2 Ceramic Implants
- •13.6.3 Polymer Implants
- •13.6.4 Composite Implants
- •13.6.5.2 Surface Coatings
- •13.7.2.1 Hydrodynamic Lubrication
- •13.7.2.2 Boundary Lubrication
- •13.7.2.3 Elastohydrodynamic Lubrication
- •13.7.3 Biomimetic Lubrication Approaches
- •13.7.3.1 Replicating Natural Lubrication Mechanisms
- •13.7.4.1 Implant Wear
- •13.7.4.3 Synovial Fluid Degradation
- •13.8.1 Hydroxyapatite Coatings
- •13.8.1.1 Bone Integration
- •13.8.1.2 Implant Stability
- •13.8.1.4 Biocompatibility
- •13.8.2 Diamond-Like Carbon Coatings
- •13.8.3 Metal Nitride Coatings
- •13.8.4 Polymeric Coatings
- •13.8.5 Nanocomposite Coatings
- •13.9.1 Pin-on-Disk Testing
- •13.9.2 Hip Joint Simulators
- •13.9.3 Knee Joint Simulators
- •13.9.4 Tribo-Corrosion Testing
- •13.9.5 Wear Debris Analysis Techniques
- •13.9.5.1 Scanning Electron Microscopy (SEM)
- •13.9.5.2 Energy-Dispersive X-Ray Spectroscopy (EDS)
- •13.10.1.1 Tailored Geometries
- •13.10.1.2 Improved Wear Characteristics
- •13.10.1.3 Accelerated Innovation
- •13.10.2.1 Real-Time Wear Monitoring
- •13.10.2.2 Functionality Assessment
- •13.10.2.3 Implant Status Monitoring
- •13.10.2.4 Patient-Centric Healthcare
- •13.10.3.1 Advanced Biomaterials
- •13.10.3.4 Multidisciplinary Approaches
- •13.10.4.1 Wear Data Analysis
- •13.10.4.2 Predictive Wear Patterns
- •13.10.4.3 Early Intervention Strategies
- •13.10.4.4 Personalized Treatment Plans
- •13.11 Conclusion
- •References
- •14.1 Introduction
- •14.2.1 Powder Bed Fusion (PBF)
- •14.2.2 Directed Energy Deposition
- •14.3.1 Extrusion-Based AM
- •14.5 Biomanufacturing
- •14.5.1 Tissue Engineering
- •14.5.2 Organ-on-a-Chip Models
- •14.6 Conclusion
- •References
- •Index

12 Bioresorbable Composite forOrthopedics andDrug Delivery Applications
337
like fracture plates, interference screws, and suture anchors, composite products
have mechanical characteristics like elastic modulus that are optimized to resemble
natural bone to reduce stress and precise degradation rate proles that promote
quicker patient healing [60–63].
12.7 Challenges
The development of novel materials with improved functional and technological
capabilities depends on the ongoing advancement of bone healing technology. The
creation of composite materials for bone regeneration that combine polymers and
ceramics is one exciting eld of study [63–67]. Compared to conventional bone
grafting materials, these materials provide several benets, such as the capacity to
be tailored to each patient’s unique requirements and a lower risk of disease transmission. The creation of polymer-ceramic biomaterials with enhanced bone regeneration capabilities has advanced signicantly in recent years [68–73].
Alloy design and fabrication plays an integral role in the performances [74–80].
Laser-assisted fabrication can be a potential method in surface modication [81–83].
Enhancing mechanical characteristics, biodegradability, and biocompatibility have
been the main focus of this progress. The difculties in producing bioresorbable
polymers, as well as their mechanical strength and cost-effectiveness, are noted.
Figure12.5 illustrates a few additional difculties [84–90]. In the development of
bioresorbable composites for orthopedics and drug delivery, challenges arise in
ensuring environmental stability [91, 92], maintaining vacuum conditions [93, 94],
and selecting appropriate manufacturing methods. Environmental factors like
Fig. 12.5 Challenges of
biocomposites in
biomedical applications

338
A. Prasad et al.
temperature and humidity can affect material integrity, while vacuum processing is
crucial for eliminating air bubbles and voids. Various manufacturing techniques,
such as solvent casting CNC [95], and 3D printing, each have specic requirements
and considerations. Additionally, achieving biocompatibility and controlled degradation kinetics is essential. Overcoming these challenges demands a multidisciplinary approach and technological advances to ensure the reliability and efcacy of
bioresorbable composites in orthopedic and drug delivery applications.
12.8 Conclusion
Although material that is bioresorbable, biocompatible, supports cell attachment,
proliferation, and maturation, and can eventually be resorbed once the new bone has
formed, allowing this bone to undergo remodeling, is ideal for a tissue-engineered
bone substitute, this goal has not yet been met. Dental implants have been developed to solve the issues with removable dental prostheses and bridges. An articial
permanent implant is used to replace the missing or damaged tooth. Prospects for
biobased resorbable composites are promising, particularly in nearly all biomedical
applications. Further research is required to fully understand the biobased resorbable composite’s cost-effectiveness, mechanical strength, and processing
approaches. The goals of research and clinical practice are complete bone regeneration and the prevention of brous encapsulation and epithelial cell migration to the
implant. However, more research is required to assess this material’s biocompatibility and biofunction.
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In: Biosensor Based Advanced Cancer Diagnostics. Elsevier, pp197–224.
52. Kumar A, Panda U, Patel VK, Kant R (2022c) Laser-Assisted Fabrication of Polymers by
Pushing Down the Limit of Resolution. Trends Fabr Polym Polym Compos 1–3.
53. Kumar A, Parihar A, Basha SN, Panda U (2022d) Clinically available/under trial drugs and
vaccines for treatment of SARS-COV-2. In: Computational Approaches for Novel Therapeutic
and Diagnostic Designing to Mitigate SARS-CoV2 Infection. Elsevier, pp451–488.
54. Kumar A, Parihar A, Panda U, Parihar DS (2022e) Microuidics-based point-of-care testing
(POCT) devices in dealing with waves of COVID-19 pandemic: The emerging solution. ACS
Appl Bio Mater 5:2046–2068.
55. Kumar A, Pathak A, Kumar A, Kumar A (2023a) Physics of Laser--Matter Interaction in
Laser-Based Manufacturing. In: Laser-based Technologies for Sustainable Manufacturing.
CRC Press, pp45–54.
56. Kumar A, Sharma AK, Katiyar JK (2023b) State-of-the-Art in Sustainable Machining of
Different Materials Using Nano Minimum Quality Lubrication (NMQL). Lubricants 11:64.
57. Sonika, Sabavath, G., Verma, S. K., Swaroop, R., & Prasad, A. (2023). New Frontiers of
Bioinspired Polymer Nanocomposite for Biomedical Applications. Advanced Materials and
Manufacturing Techniques for Biomedical Applications, 135–155.
58. Adeosun, S.O., Lawal, G.I., & Gbenebor, O. P. (2014). Characteristics of Biodegradable
Implants, (March), 88–106.
59. Babu, R.P., O’Connor, K., & Seeram, R. (2013). Current progress on bio-based polymers and
their future trends. Progress in Biomaterials, 2(1), 8. https://doi.org/10.1186/2194- 0517- 2- 8.
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60. Kumar A, Shrama AK, Gupta TVK, Katiyar JK (2022f) Inuence of hexagonal boron nitride
additive nanocutting uid on the machining of AA6061-T6 alloy using minimum quality lubrication. Proc Inst Mech Eng Part E J Process Mech Eng 09544089221110980.
61. Kumar S, Verma RK, Kumar A, Patel VK (2022g) Importance of Chemically Treated Natural
Fibers in the Fabrication of Natural Fiber Reinforced Polymer Composites. Trends Fabr Polym
Polym Compos 10–11.
62. Leventini SD, Martin-Gutierrez BS, Kumar A, Mittman AS, Kim SM, Martini A (2022) Tactile
Perception of Vellum Quantied by Friction and Surface Roughness. Tribol Lett 70:127.
63. Mehra AK, Saini R, Kumar A (2021) The effect of bre contents on mechanical and moisture
absorption properties of gourd sponge/coir bre reinforced epoxy hybrid composites. Compos
Commun 25:100732.
64. Parihar A, Kumar A, Panda U, Khan R, Parihar DS, Khan R (2023) Cryopreservation: A
Comprehensive Overview, Challenges, and Future Perspectives. Adv Biol 2200285.
65. Parihar A, Pandita V, Kumar A, Parihar DS, Puranik N, Bajpai T, Khan R (2021) 3D Printing:
Advancement in Biogenerative Engineering to Combat Shortage of Organs and Bioapplicable
Materials. Regen Eng Transl Med 1–27.
66. Parmar V, Kumar A, Mani Sankar M, Datta S, Vijaya Prakash G, Mohanty S, Kalyanasundaram
D (2018) Oxidation facilitated antimicrobial ability of laser micro-textured titanium alloy
against gram-positive Staphylococcus aureus for biomedical applications. J Laser Appl 30.
67. Parmar V, Kumar A, Prakash GV, Datta S, Kalyanasundaram D (2019) Investigation, modelling and validation of material separation mechanism during ber laser machining of medical
grade titanium alloy Ti6Al4V and stainless steel SS316L.Mech Mater 137.
68. Pathak A, Kumar A, Kumar A, Kumar A (2023) Application of Laser Technology in
the Mechanical and Machine Manufacturing Industry. In: Laser-based Technologies for
Sustainable Manufacturing. CRC Press, pp107–155.
69. Saurabh Gupta Ruchika Saini AKPS (2020) Performance Analysis of Gudgeon Pin of Various
Cross Sections by FEM.Int J Recent Technol Eng 8:4569–4573.
70. Shrivastava Prateek SR, Kumar A, others (2020) Investigation of Torsional Rod to Minimize
Vibration in Automobile using ANSYS.In: 2020 1st International Conference on Innovative
Research in Applied Science, Engineering and Technology (IRASET). pp1–6.
71. Singh RK, Kumar A, Kant R, Gupta A, Suresh E, Bhattacharya S (2014b) Design and fabrication of 3-dimensional helical structures in polydimethylsiloxane for ow control applications.
Microsyst Technol 20:101–111.
72. Subramanian Y, Gajendiran J, Veena R, Azad AK, Sabarish VCB, Muhammed Ali SA, Kumar
A, Gubendiran RK (2023) Structural, Photoabsorption and Photocatalytic Characteristics
of BiFeO3-WO3 Nanocomposites: An Attempt to Validate the Experimental Data Through
SVM-Based Articial Intelligence (AI). J Electron Mater 1–11.
73. Vats P, Gajrani KK, Kumar A (2023) Laser-Based Additive Manufacturing. In: Laser-based
Technologies for Sustainable Manufacturing. CRC Press, pp67–83.
74. Chakraborty, S.; Gupta, A. K.; Roy, D.; Basumallick, A.Studies on Nano-Metal Dispersed
Cu-Cr Matrix Composite. Materials Letters 2019, 257 (September), 126739. https://doi.
org/10.1016/j.matlet.2019.126739.
75. Roy, D.; Gupta, A.K.; Alam, S.; Srikanth, S.; Jha, B.K. Enhancement of Properties of MicroAlloyed Low-Carbon Ni-Added Steel by Thermomechanical Treatment. Journal of Materials
Engineering and Performance 2020. https://doi.org/10.1007/s11665- 020- 05311- w.
76. Chakraborty, S.; Gupta, A. K.; Roy, D.; Basu Mallick, A. Nanomechanical Properties of
Mechanically Alloyed and Spark Plasma Sintered W-Nanoparticulate Dispersed Cu-Nb
Alloys. Materials Letters 2020, 274, 128004. https://doi.org/10.1016/j.matlet.2020.128004.
77. Gupta, A. K.; Mallik, B.; Roy, D. Materials Performance and Characterization Structure
Property Correlation of In Situ Reinforced Al– Based Metal Matrix Composite via Stir Casting
Structure Property Correlation of In Situ Reinforced Al– Based Metal Matrix Composite via
Stir Casting. 2020, 9 (1). https://doi.org/10.1520/MPC20190038.
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12 Bioresorbable Composite forOrthopedics andDrug Delivery Applications
78. Roy, D.; Pal, S.; Tiwary, C.S.; Gupta, A.K.; Babu, P.N.; Mitra, R. Stable Nanocrystalline
Structure Attainment and Strength Enhancement of Cu Base Alloy Using Bi- Modal
Distributed Tungsten Dispersoids. Philosophical Magazine 2021, 0 (0), 1–21. https://doi.org/1
0.1080/14786435.2021.1988173.
79. Roy, D.; Chakraborty, S.; Gupta, A. K.; BasuMallick, A.; Scattergood, R. O.; Koch,
C.C. Synergistic Effect of Nb and Zr Additions on the Structure-Property Relationships of
Nanocrystalline Cu Processed by Mechanical Alloying and Hot Pressing. Journal of Alloys
and Compounds 2021, 854, 157174. https://doi.org/10.1016/j.jallcom.2020.157174.
80. Roy, D.; Chakraborty, S.; Gupta, A.K.; Basu Mallick, A.; Koch, C.C. Synergistic Effect of Nb
and Zr Addition in Thermal Stabilization of Nano-Crystalline Cu Synthesized by Ball Milling.
Materials Letters 2020, 271, 127780. https://doi.org/10.1016/j.matlet.2020.127780.
81. Soumya Mandal, Ashish Kumar Gupta, Elena Echeverria, David N. McIlroy, Jonathan
D. Poplawsky, R. S. Laser-Assisted Nanofabrication of Multielement Complex Oxide.
Materials & Design 2022, 220, 110882. https://doi.org/10.1016/j.matdes.2022.110882.
82. Gupta, A.K.; Gupta, S.; Mandal, S.; Sachan, R.Laser Irradiation-Induced Nanoscale Surface
Transformations in Strontium Titanate. 2022, 1–12.
83. Gupta, A. K.; Gupta, S.; Sachan, R. Laser Irradiation Induced Atomic Structure
Modications in Strontium Titanate. JOM 2022, 74 (1), 143–150. https://doi.org/10.1007/
s11837- 021- 04996- 1.
84. Bernardo, M.P., da Silva, B. C. R., Hamouda, A.E. I., de Toledo, M. A. S., Schalla, C.,
Rütten, S., … Sechi, A. (2022). PLA/Hydroxyapatite scaffolds exhibit invitro immunological inertness and promote robust osteogenic differentiation of human mesenchymal stem
cells without osteogenic stimuli. Scientic Reports, 12(1), 1–15. https://doi.org/10.1038/
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85. Kohane, D.S., & Langer, R. (2008). Polymeric biomaterials in tissue engineering. Pediatric
Research, 63(5), 487–491. https://doi.org/10.1203/01.pdr.0000305937.26105.e7.
86. Kumar, A., Singh Gangwar, A.K., Kumar, A., Meena, C.S., Singh, V.P., Dutt, N., … Gori,
Y. (2022). Biomedical study of femur bone fracture and healing. In Advanced Materials for
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87. Li, X., Cui, R., Sun, L., Aifantis, K.E., Fan, Y., Feng, Q., … Watari, F. (2014). 3D-printed biopolymers for tissue engineering application. International Journal of Polymer Science, 2014.
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88. Nezakati, T., Seifalian, A., Tan, A., & Seifalian, A. M. (2018). Conductive Polymers :
Opportunities and Challenges in Biomedical Applications. Chemical Reviews, 118,
6766–6843. review-article. https://doi.org/10.1021/acs.chemrev.6b00275.
89. Prasad, A., Chakraborty, G., & Kumar, A. (2022). Bio-based environmentally benign polymeric resorbable materials for orthopedic xation applications. In Advanced Materials for
Biomedical Applications (pp. 251–266). Boca Raton: CRC Press. https://doi.org/10.120
1/9781003344810- 15.
90. Waizy, H., Seitz, J. M., Reifenrath, J., Weizbauer, A., Bach, F. W., Meyer-Lindenberg, A.,
Windhagen, H. (2013). Biodegradable magnesium implants for orthopedic applications.
Journal of Materials Science, 48(1), 39–50. https://doi.org/10.1007/s10853- 012- 6572- 2.
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V., Raina, A. (eds) Proceedings of International Conference on Intelligent Manufacturing
and Automation. Lecture Notes in Mechanical Engineering. Springer, Singapore. https://doi.
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Conservation and Effective Utilization of Waste Heat from Air Conditioner’, IOP Conference
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Fryer. In: Vasudevan, H., Kottur, V., Raina, A. (eds) Proceedings of International Conference
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and Portable Smart CNC Machine. In: Vasudevan, H., Kottur, V., Raina, A. (eds) Proceedings
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A. Prasad et al.

Chapter 13
Wear andFriction Mechanism Study
inKnee andHip Rehabilitation:
AComprehensive Review
AmitChoudhari, AshishKumarGupta , AbhishekKumar ,
AvinashKumar , AshutoshGupta , NusratChowdhury ,
andAshwaniKumar
Abstract Wear and friction mechanisms in knee and hip rehabilitation have been a
focus of intense research due to their critical importance in the longevity and performance of prosthetic implants. This comprehensive review explores the key factors
inuencing the selection of hip and knee prosthetics, ranging from implant longevity and wear mechanisms to biological responses to wear debris, material selection,
A. Choudhari (*)
Mechanical Engineering Department, Cleveland State University, Cleveland, OH, USA
e-mail: a.choudhari@vikes.csuohio.edu
A. K. Gupta
School of Mechanical and Aerospace Engineering, Oklahoma State University,
Stillwater, OK, USA
e-mail: ashish.gupta10@okstate.edu
A. Kumar
J.Mike Walker ’66 Department of Mechanical Engineering, Texas A&M University,
College Station, TX, USA
Department of Mechanical Engineering, University of California, Merced, Merced, CA, USA
e-mail: akumar71@tamu.edu
A. Kumar
Department of Mechanical Engineering, Indian Institute of Information Technology Design &
Manufacturing (IIITDM), Kancheepuram, Chennai, Tamil Nadu, India
Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
e-mail: avikr@iiitdm.ac.in
A. Gupta
Department of Zoology, Dayanand Vedic College, Orai, UP, India
N. Chowdhury
University of Illinois Urbana-Champaign, Urbana, IL, USA
e-mail: nusratc2@illinois.edu
A. Kumar
Department of Mechanical Engineering, Technical Education Department Uttar Pradesh
(under Government of Uttar Pradesh), Kanpur, Uttar Pradesh, India
A. Kumar et al. (eds.), Applications of Biotribology in Biomedical Systems,
https://doi.org/10.1007/978-3-031-58327-8_13
345© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024

346
A. Choudhari et al.
design strategies, and patient-specic considerations. The clinical impact and regulatory standards governing these prosthetics are also examined. Various musculoskeletal conditions related to bones, including osteoporosis, bone cancer, congenital
anomalies, war-related injuries, and unexpected incidents, collectively result in a
yearly economic burden of $136.8 billion on the United States economy. The review
further classies types of hip and knee replacements, including total hip replacement (THR) and resurfacing hip replacement (RHR). It underscores the clinical
signicance of wear and friction in these contexts. Types of wear in knee and hip
joints, such as adhesive, abrasive, fatigue, and corrosion/oxidative wear, are discussed, along with materials selection for implants, encompassing metallic, ceramic,
polymer, and composite options. Various surface modications for enhancing wear
resistance are also explored, including ion implantation, surface coatings, and biomimetic modications. Lubrication strategies in hip and knee replacement, the role
of synovial uid, and lubrication techniques in articial joints are reviewed alongside emerging surface coatings for wear resistance, such as hydroxyapatite,
diamond- like carbon, and metal nitride coatings. Experimental approaches to wear
and friction studies, including pin-on-disk testing, joint simulators, tribo-corrosion
testing, and wear debris analysis techniques, are analyzed, with a focus on future
directions and emerging technologies like additive manufacturing, smart implants,
biomaterial innovations, and articial intelligence in wear prediction. This review
concludes by summarizing the current state of knowledge in wear and friction
mechanisms in knee and hip rehabilitation and outlines future research directions in
this critical area.
Keywords Wear and friction mechanisms · Knee and hip joint · Lubrication ·
Additive manufacturing · Smart implant · Articial intelligence
13.1 Introduction
Since its initial use, hip prosthetic design and material development have advanced
steadily. In implant technology, its development is one of the century’s most difcult problems. The rst hip operations were performed in England in 1750 to treat
cases of arthritis [1]. Early hip prostheses were made from wood, ivory, and natural
polymers like rubber. These tended to have poor durability and integration. This
treatment was terrible since the body was exposed to wear particles. The earliest
suggestion for treating a hip injury was to replace it with a prosthesis in 1840 [2, 3].
It was only possible to replace or resurface the acetabular portion of the femoral
head during this treatment. A decade later, around 1930s–1950s, stainless steel,
cobalt-chromium alloys and polyethylene became more commonly used in hip
implants, though longevity was still a problem. In the 1960s–1970s titanium alloys
were introduced. Titanium had improved biocompatibility and corrosion resistance
compared to earlier materials. In the 1980s–1990s ceramic materials like alumina
and zirconia were explored as alternatives to address wear and durability issues.
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