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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5881_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Aim and Scope
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •About the Editors
- •1.1 Introduction
- •1.2.1 Friction
- •1.2.1.3 Friction Under Lubricated Conditions
- •1.7.1 Joint Tribology
- •1.7.2 Skin Tribology
- •1.7.3 Oral Tribology
- •1.8 Summary
- •References
- •2.1 Introduction
- •2.3.1 Fluid Pressurization/Fluid-Film Lubrication
- •2.3.2 Boundary Lubrication
- •2.3.3 Hydrodynamic Lubrication
- •2.3.4 Squeeze-Film Lubrication
- •2.3.5 Synovial Fluid
- •2.3.6 Hydration Lubrication
- •2.5.2 Scaffolds
- •2.5.3 Synthetic Polymer
- •2.5.4 Polyacrylamide
- •2.5.5 PEG Hydrogel
- •2.5.6 PVA Hydrogel
- •2.5.7 Double Network Hydrogel
- •2.5.8 Triple Network Hydrogel
- •2.6.1 Polyacrylamide
- •2.6.2 PEG Hydrogel
- •2.6.3 PVA Hydrogel
- •2.6.4 Double Network Hydrogel
- •2.6.5 Triple Network Hydrogel
- •2.7.1 Mechanical Properties
- •2.7.2 Structural Properties
- •2.8 Conclusion
- •References
- •3.1 Introduction
- •3.3.1 Label-Based Biosensors
- •3.3.2 Label-Free Biosensors
- •3.4 Different Nanobiosensing Techniques
- •3.4.1 Optical Sensing
- •3.4.2 Electrochemical/Electrical Sensing
- •3.4.3 Magnetic Sensing
- •3.4.4 Mass-Based Sensing
- •3.6.2 Neurodegenerative Diseases
- •3.6.3 Infectious Diseases
- •3.6.4 Metabolic Diseases
- •References
- •4.1 Introduction
- •4.2.1 Surface Functionalization
- •4.2.2 Bioconjugation
- •4.3 Synthesis Approach
- •4.3.1 Hydrothermal Method
- •4.3.2 Chemical Vapor Deposition (CVD)
- •4.3.3 Wet Chemical Method
- •4.4 Plasmonic Black Bodies (PBBs)
- •4.4.1 Gold NP (AuNPs)-Based PBB
- •4.4.2 Silver NPs (Ag NPs)-Based PBB
- •4.4.3 Platinum NPs (Pt NPs)-Based PBB
- •4.5 Biomimetic NP
- •4.6 Upconverting NP (UCNP)
- •4.6.1 Synthesis
- •4.7 Inorganic NP
- •4.7.1 Synthesis
- •4.8 Photothermal Therapy (PTT)
- •4.9 Conclusion
- •References
- •5.1 Introduction
- •5.2 Human Skin
- •5.10 Future Scope
- •5.11 Conclusion
- •References
- •6.1 Introduction
- •6.1.1 Class 1
- •6.1.2 Class 2
- •6.1.3 Class 3
- •6.4.1.1 Surface Patterning
- •6.4.1.2 Direct-Write Patterning
- •6.4.1.5 Dip-Pen Nanotechnology
- •6.4.1.7 Composing Using Beams
- •6.4.1.8 Direct Write Photolithography (DWP)
- •6.4.1.9 Light-Beam Lithography Electron
- •6.4.1.10 Focused Ion Beam Lithography
- •6.4.2 Fabrication Techniques
- •6.4.2.4 Non-invasive Glucose Monitoring Devices Technique
- •6.4.2.6 Cost-Effective Electrochemical Voltametric Sensors Techniques
- •6.4.2.7 Three-Dimensional (3D) Printing Techniques
- •6.4.2.8 UV-LED Stereolithography Printer Technique
- •6.4.2.9 4D Printing Techniques
- •6.4.2.10 Advanced Biomedical Techniques Involving Biorobots
- •References
- •7.1 Introduction
- •7.6 Mechanical Biocompatibility Challenges
- •7.7 Poor Bio-Printing Resolution
- •7.9 Limited Biomaterial Selection
- •7.11 Conclusion
- •8.2 Animal Tribology
- •8.2.1 Joint
- •8.2.3 Integumentary Change
- •References
- •8.1 Introduction
- •8.3.1 Nanotribology
- •8.4 Green Tribology
- •8.5 Conclusion
- •References
- •9.1 Introduction
- •9.2 Bio-Tribological Issues
- •9.3.2 Bone Fracture Fixation
- •9.3.4 Cardiovascular Devices
- •9.3.5 Minimal Invasive Surgical Devices
- •References
- •10.1 Introduction
- •10.2.2.1 Structural Integrity
- •10.2.2.2 Controlled Release Properties
- •10.2.2.3 Enhanced Drug Loading Capacity
- •10.2.2.4 Tailored Material Properties
- •10.2.3.1 Biocompatibility
- •10.2.3.3 Mechanical Properties
- •10.2.3.4 Drug Compatibility
- •10.2.3.5 Fabrication Compatibility
- •10.3.1 Matrix Material Properties
- •10.3.4 Biocompatibility Assessment
- •10.3.4.1 In Vitro Cell Culture Studies
- •10.3.4.2 Hemocompatibility Studies
- •10.3.4.3 In Vivo Animal Studies
- •10.3.4.4 Histological Analysis
- •10.3.4.5 Immune Response Evaluation
- •10.3.4.6 Biodegradation Assessment
- •10.4 Surface Engineering Considerations
- •10.4.2.1 Surface Coatings
- •10.4.2.2 Plasma Treatment
- •10.4.2.3 Surface Grafting
- •10.4.2.4 Dip Coating
- •10.4.2.5 Spray Coating System
- •10.4.2.6 Electrotreated Coating
- •10.4.2.9 Microfabrication Techniques
- •10.4.2.10 Surface Roughness Control
- •10.5.1.2 Mechanical Properties
- •10.5.1.3 Surface Characteristics
- •10.5.1.4 Release Kinetics Analysis
- •10.5.1.5 Biological Compatibility
- •10.5.1.7 Other Analyses
- •10.6 Advanced Fabrication Techniques
- •10.8 Conclusion
- •References
- •11.1 Introduction
- •11.2 Shape Memory Alloys (SMA)
- •11.3 Shape Memory Polymers
- •11.3.1 Heat
- •11.3.2 Light
- •11.3.3 Magnetic Field
- •11.4 Shape-Changing Hydrogels
- •11.5 Biomedical Applications
- •11.6 Conclusion
- •References
- •12.1 Introduction
- •12.3 Bioresorbable Orthopedic Implants
- •12.4.1 Polylactides
- •12.4.2 Poly (Ortho Esters)
- •12.4.3 Polyphosphoesters
- •12.4.4 Polyphosphazenes
- •12.4.5 Polycaprolactone
- •12.4.6 Polyurethanes
- •12.4.7 Polycarbonates
- •12.5.1 Compression Molding
- •12.5.2 Transfer Molding
- •12.5.3 Injection Molding
- •12.5.4 Extrusion
- •12.5.5 Blow Molding
- •12.5.6 Calendering Process
- •12.5.7 Fiber Spinning
- •12.5.8 Thermoforming
- •12.5.9 Polymer Foaming
- •12.7 Challenges
- •12.8 Conclusion
- •References
- •13.1 Introduction
- •13.3.1.1 Total Hip Replacement (THR)
- •13.3.2 Resurfacing Hip Replacement (RHR)
- •13.5.1 Adhesive Wear
- •13.5.2 Abrasive Wear
- •13.5.3 Fatigue Wear
- •13.5.4 Corrosion/Oxidative Wear
- •13.5.5 Surface Cracking
- •13.6.1 Metallic Implants
- •13.6.1.1 Stainless Steel
- •13.6.1.2 Co-Cr Alloys
- •13.6.1.3 Ti-Alloy
- •13.6.2 Ceramic Implants
- •13.6.3 Polymer Implants
- •13.6.4 Composite Implants
- •13.6.5.2 Surface Coatings
- •13.7.2.1 Hydrodynamic Lubrication
- •13.7.2.2 Boundary Lubrication
- •13.7.2.3 Elastohydrodynamic Lubrication
- •13.7.3 Biomimetic Lubrication Approaches
- •13.7.3.1 Replicating Natural Lubrication Mechanisms
- •13.7.4.1 Implant Wear
- •13.7.4.3 Synovial Fluid Degradation
- •13.8.1 Hydroxyapatite Coatings
- •13.8.1.1 Bone Integration
- •13.8.1.2 Implant Stability
- •13.8.1.4 Biocompatibility
- •13.8.2 Diamond-Like Carbon Coatings
- •13.8.3 Metal Nitride Coatings
- •13.8.4 Polymeric Coatings
- •13.8.5 Nanocomposite Coatings
- •13.9.1 Pin-on-Disk Testing
- •13.9.2 Hip Joint Simulators
- •13.9.3 Knee Joint Simulators
- •13.9.4 Tribo-Corrosion Testing
- •13.9.5 Wear Debris Analysis Techniques
- •13.9.5.1 Scanning Electron Microscopy (SEM)
- •13.9.5.2 Energy-Dispersive X-Ray Spectroscopy (EDS)
- •13.10.1.1 Tailored Geometries
- •13.10.1.2 Improved Wear Characteristics
- •13.10.1.3 Accelerated Innovation
- •13.10.2.1 Real-Time Wear Monitoring
- •13.10.2.2 Functionality Assessment
- •13.10.2.3 Implant Status Monitoring
- •13.10.2.4 Patient-Centric Healthcare
- •13.10.3.1 Advanced Biomaterials
- •13.10.3.4 Multidisciplinary Approaches
- •13.10.4.1 Wear Data Analysis
- •13.10.4.2 Predictive Wear Patterns
- •13.10.4.3 Early Intervention Strategies
- •13.10.4.4 Personalized Treatment Plans
- •13.11 Conclusion
- •References
- •14.1 Introduction
- •14.2.1 Powder Bed Fusion (PBF)
- •14.2.2 Directed Energy Deposition
- •14.3.1 Extrusion-Based AM
- •14.5 Biomanufacturing
- •14.5.1 Tissue Engineering
- •14.5.2 Organ-on-a-Chip Models
- •14.6 Conclusion
- •References
- •Index

Contents
1 Introduction to Biotribology: A Science of Surface Interaction . . . . . 1
Abhishek Kumar, Avinash Kumar, Ashwani Kumar,
Amit Choudhari, Ashish Kumar Gupta, and Sakib Faisal
2 Characterization of Hydrogel Properties in the Advancement
of Bio-Tribology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
Nusrat Chowdhury, Sakib Faisal, Abhishek Kumar,
Amit Choudhari, Ashish Kumar Gupta, Avinash Kumar,
and Ashwani Kumar
3 Recent Advancements in Developing Nanobiosensors
for Treating Inflammatory Diseases of Human:
A Comprehensive Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Ankita Chakraborty, Saubhik Mitra, Moytrey Chatterjee,
Abhijit Dey, and Suprabhat Mukherjee
4 Biological Smart Materials: Materials for Cancer Treatment . . . . . . 113
Debasish Panda, Mansi Agarwal, Beauty Kumari,
Prabhudutta Hota, and Ajay Agarwal
5 Tribological Measurements of Human Skin . . . . . . . . . . . . . . . . . . . . . 149
Ayushi Pal, Reetu Gour, Ashwani Kumar, Abhishek Kumar,
Avinash Kumar, and Nusrat Chowdhury
6 Tribological Hurdles in Biomedical Manufacturing:
A Comprehensive Examination . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167
Avinash Kumar, Pradipta Gajjar, Kavitha Sharanappa Gudadur,
Abhishek Kumar, Ashish Kumar Gupta, Amit Choudhari,
Nusrat Chowdhury, and Ashwani Kumar
xiii

xiv
Contents
7 Navigating the Landscape: Cutting-Edge Biomedical
Manufacturing Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
Milad Heidari, Sivasakthivel Thangavel, Pooyan Rahmanivahid,
Morteza Khashehchi, Ashwani Kumar, Abhishek Kumar,
and Avinash Kumar
8 Animal Tribology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217
Reetu Gour, Nikki Baliyan, Ayushi Pal, Ashwani Kumar,
Avinash Kumar, and Abhishek Kumar
9 Medical Devices Tribology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235
Nipun Jain, Yusuf Olatunji Waidi, Saswat Chowdhury,
Ranjit Barua, Samir Das, Arbind Prasad, and Sudipto Datta
10 Composites for Drug-Eluting Devices: Emerging Biomedical
Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251
Ashish Kumar Gupta, Amit Choudhari, Abhishek Kumar,
Avinash Kumar, Anamika Gupta, Sakib Faisal, and Ashwani Kumar
11 Biological Smart Biomaterials: Materials for Biomedical
Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313
Saswat Chowdhury, Nipun Jain, Yusuf Olatunji Waidi,
Ranjit Barua, Samir Das, Arbind Prasad, and Sudipto Datta
12 Bioresorbable Composite for Orthopedics and Drug Delivery
Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327
Arbind Prasad, Sudipto Datta, Sriparna De, Pavitra Singh,
and Bidyanand Mahto
13 Wear and Friction Mechanism Study in Knee and Hip
Rehabilitation: A Comprehensive Review . . . . . . . . . . . . . . . . . . . . . . 345
Amit Choudhari, Ashish Kumar Gupta, Abhishek Kumar,
Avinash Kumar, Ashutosh Gupta, Nusrat Chowdhury,
and Ashwani Kumar
14 Challenges and Perspective of Manufacturing Techniques
in Biomedical Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433
Yusuf Olatunji Waidi, Nipun Jain, Saswat Chowdhury,
Ranjit Barua, Samir Das, Arbind Prasad, and Sudipto Datta
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447

Contributors
Ajay Agarwal RIMS Group, Indian Institute of Technology (I.I.T), Jodhpur,
Rajasthan, India
Department of Electrical Engineering, Indian Institute of Technology (I.I.T),
Jodhpur, Rajasthan, India
MansiAgarwal Department of Bioscience and Bioengineering, Indian Institute of
Technology (I.I.T), Jodhpur, Rajasthan, India
NikkiBaliyan Chaudhary Charan Singh University, Meerut, Uttar Pradesh, India
RanjitBarua Centre for Healthcare Science and Technology, Indian Institute of
Engineering Science and Technology, Howrah, West Bengal, India
Ankita Chakraborty Integrative Biochemistry and Immunology Laboratory
(IBIL), Department of Animal Science, Kazi Nazrul University, Asansol, West
Bengal, India
MoytreyChatterjee Department of Life Sciences, Presidency University, Kolkata,
West Bengal, India
AmitChoudhari Mechanical Engineering Department, Cleveland State University,
Cleveland, OH, USA
NusratChowdhury University of Illinois Urbana-Champaign, Urbana, IL, USA
SaswatChowdhury Department of Bioengineering, Indian Institute of Science,
Bangalore, Karnataka, India
SamirDas Biomaterials and Tissue Engineering Lab, School of Medical Science
and Technology Indian Institute of Technology, Kharagpur, West Bengal, India
SudiptoDatta Department of Materials Engineering, Indian Institute of Science,
Bangalore, Karnataka, India
Sriparna De Department of Allied Health Sciences, Brainware University,
Kolkata, West Bengal, India
xv

xvi
Contributors
Abhijit Dey Integrative and Immunology Laboratory (IBIL), Department of
Animal Science, Kazi Nazrul University, Asansol, West Bengal, India
SakibFaisal South Dakota State University, Brookings, SD, USA
Pradipta Gajjar Department of Mechanical Engineering, Indian Institute of
Information Technology Design and Manufacturing (IIITDM) Kancheepuram,
Chennai, Tamil Nadu, India
Reetu Gour Department of Microbiology, IIMT University, Meerut, Uttar
Pradesh, India
KavithaSharanappaGudadur Department of Mechanical Engineering, Indian
Institute of Information Technology Design and Manufacturing (IIITDM)
Kancheepuram, Chennai, Tamil Nadu, India
Anamika Gupta Department of General Surgery, Ganesh Shankar Vidyarthi
Memorial Medical College, Kanpur, Uttar Pradesh, India
Ashish Kumar Gupta School of Mechanical and Aerospace Engineering,
Oklahoma State University, Stillwater, OK, USA
Ashutosh Gupta Department of Zoology, Dayanand Vedic College, Orai, Uttar
Pradesh, India
Milad Heidari Mechanical Engineering Department, Global College of
Engineering and Technology, Muscat, Oman
PrabhuduttaHota Department of Biotechnology, National Institute of Technology
(N.I.T), Rourkela, Odisha, India
Nipun Jain Department of Materials Engineering, Indian Institute of Science,
Bangalore, Karnataka, India
Morteza Khashehchi Mechanical Engineering Department, Global College of
Engineering and Technology, Muscat, Oman
Abhishek Kumar J. Mike Walker ’66 Department of Mechanical Engineering,
Texas A&M University, College Station, TX, USA
Department of Mechanical Engineering, University of California, Merced,
Merced, CA, USA
Ashwani Kumar Department of Mechanical Engineering, Technical Education
Department Uttar Pradesh (under Government of Uttar Pradesh), Kanpur, Uttar
Pradesh, India
Avinash Kumar Department of Mechanical Engineering, Stanford University,
Stanford, CA, USA
Department of Mechanical Engineering, Indian Institute of Information Technology
Design & Manufacturing (IIITDM), Kancheepuram, Chennai, Tamil Nadu, India

Contributors
xvii
BeautyKumari Department of Bioscience and Bioengineering, Indian Institute of
Technology (I.I.T), Jodhpur, Rajasthan, India
BidyanandMahto Government Engineering College, Vaishali (Under Department
of Science, Technology and Technical Education, Government of Bihar), Vaishali,
Bihar, India
SaubhikMitra Department of Health and Family Welfare, Government of West
Bengal, Santipur Block, Nadia, West Bengal, India
Suprabhat Mukherjee Integrative Biochemistry and Immunology Laboratory
(IBIL), Department of Animal Science, Kazi Nazrul University, Asansol, West
Bengal, India
Ayushi Pal Department of Microbiology, IIMT University, Meerut, Uttar
Pradesh, India
Debasish Panda RIMS Group, Indian Institute of Technology (I.I.T), Jodhpur,
Rajasthan, India
Department of Electrical Engineering, Indian Institute of Technology (I.I.T),
Jodhpur, Rajasthan, India
Department of Biomedical Engineering, All Indian Institute of Medical Science
(AIIMS), Jodhpur, Rajasthan, India
Arbind Prasad Mechanical Engineering Department, Katihar Engineering
College (Under Department of Science, Technology and Technical Education,
Government of Bihar), Katihar, Bihar, India
PooyanRahmanivahid Mechanical Engineering Department, Global College of
Engineering and Technology, Muscat, Oman
PavitraSingh Foundry Technology, National Institute of Advanced Manufacturing
Technology (NIAMT), Hatia, Ranchi, Jharkhand, India
SivasakthivelThangavel Mechanical Engineering Department, Global College of
Engineering and Technology, Muscat, Oman
Yusuf Olatunji Waidi Department of Materials Engineering, Indian Institute of
Science, Bangalore, Karnataka, India

About the Editors
AbhishekKumar is currently working as a graduate assistant (PhD scholar) in the
J. Mike Walker ’66 Department of Mechanical Engineering at Texas A&M
University, College Station. He received his MS in Mechanical Engineering (2023)
from the University of California Merced, USA; MTech in Design Engineering
(2016) from Indian Institute of Technology Delhi, India, in 2016; and Bachelor of
Engineering degree (honors) in Mechanical Engineering (2014) from Rajiv Gandhi
Proudyogiki Vishwavidyalaya, Bhopal. He has worked as an assistant professor at
Jabalpur Engineering College, Jabalpur (2018–2020); Galgotias University, Greater
Noida (2017); and Parul University, Vadodara (2016–2017). He was a summer visiting researcher at Indian Institute of Technology Kanpur (2018). He qualied
GATE-2014 with 99.25 percentile in 2014 and was awarded GATE fellowship by
the Government of India. His MTech thesis was based on the investigation of nanowear in Mg-based composites in collaboration with National University of
Singapore, Singapore. He has a very keen interest to work on the tribological characterization of interacting surfaces. He has experience of more than 8years as an
assistant professor and a graduate student researcher to work with tribological systems and their surface and wear characterization. He has gained hands-on experience of working with sophisticated experimental equipment in the past 8.5years
and has utilized his experimental skills to successfully complete more than ten
research projects with reputed industrial partners such as Chevron Corporation,
SpaceX, Chevron- Phillips, Lawrence Livermore National Laboratory, etc. and academic collaborators such as National University of Singapore, Indian Institute of
Technology Kanpur, California State University Chico, Illinois State University
Normal, etc. He has utilized his exposure to demanding and challenging projects by
publishing four peer-reviewed articles in peer-reviewed journals and presenting his
work in ve international conferences and publishing articles in two conference
proceedings. He has worked as book editor and book proposal reviewer for CRC
Press, Taylor & Francis USA, and reviewed two book proposals, edited one book,
and authored six book chapters. He has enthusiasm to learn about the advanced
research, and he frequently volunteers as a peer- reviewer for more than six high
impact journals (Journal of Magnesium and Alloys (IF = 17.6), Lubricants
xix

xx
About the Editors
(IF = 3.584), Journal of Composites Science (IF = 3.3), Tribology Transactions
(IF=2.056), Inorganic Chemistry Communications (IF=3.8), and Materials Today:
Proceedings (CS= 3.2), and has been recognized as a certied peer reviewer by
Elsevier and MDPI.He has been selected as the Outstanding Reviewer twice by the
Journal of Magnesium and Alloys (17.6 impact factor) due to his extraordinary contributions to the journal. He is also member of several professional societies such as
the American Society of Mechanical Engineers (ASME), the Society of Tribologists
and Lubrication Engineers (STLE), the American Ceramic Society (ACerS), the
Association for Iron and Steel Technology (AIST), the Minerals, Metals and
Materials Society (TMS), and ASM International (ASM). His research contributions have been acknowledged by STLE, and he has been selected as the technical
editor for Tribology and Lubrication Technology (TLT) magazine by STLE.He is
also the recipient of several awards and honors, including 2024 Houston Section
Scholarship by STLE.He is currently involved in the research that involves tribology, mechanical behavior of materials, material characterization, mechanical testing, mechanical properties, microstructure, nanomaterials, material characteristics,
materials, and materials processing.
AvinashKumar is currently working as an assistant professor in the Department
of Mechanical Engineering at the Indian Institute of Information Technology,
Design and Manufacturing (IIITD&M), Kancheepuram, Chennai (an institute of
national importance under Ministry of Education, Government of India). He is a
visiting research professor, Stanford University California, USA.His research interests include micro/nanofabrication, laser machining, surface engineering for microudics, and MEMS/micro/bio-devices. He has published more than 14 international
journals, 12 chapters, 3 books, and 10 international conference papers. His google
scholar ID is eiJdMdoAAAAJ, ORCID ID is 0000-0002-8071-5748, Scopus ID is
56564412000, and Web of Science Researcher ID is P-6124-2018. He is a reviewer
in ASME Journal of Solar Energy Engineering, Journal of Engineering Applications
of Computational Fluid Mechanics, ASME Journal of Heat Transfer, Journal of
Physics of Fluids, and many more. He worked as a post-doctoral fellow at Indian
Institute of Technology Kanpur until 2019. His post-PhD research experience
includes early post-doctoral fellow in the Department of Mechanical Engineering,
Indian Institute of Technology Delhi. He also worked as an assistant professor
(TEQIP faculty) in a World Bank and MHRD-(Government of India) project (NPIU)
for a semester (2018) at THDC- Institute of Hydropower Engineering and Technology
Tehri (Uttarakhand). He obtained his PhD from the Department of Mechanical
Engineering, Indian Institute of Technology, Delhi, in 2018. He received his
Bachelor of Engineering in Mechanical Engineering from Rajiv Gandhi Proudyogiki
Vishwavidyalaya, Bhopal in 2010 and M.Tech degree in Mechanical Engineering
from Indian Institute of Technology Kanpur, India, in 2012. He was a research associate at the Bio-MEMS and Micro-uidics Laboratory, Indian Institute of Technology
Kanpur, India, from August 2012 to November 2012. He worked as research associate with Prof. G. K. Ananthsuresh and Prof. Ashitava Ghoshal in Robert Bosch
Centre for Cyber Physical system, Mechanical Engineering Department, Indian

About the Editors
xxi
Institute of Science, Bangalore, for a year (2013). He qualied Indian Engineering
Services in 2010. He qualify GATE-2010 with 98.20% in 2010. His PhD thesis was
nominated for Best Thesis Award by the foreign and Indian examiner. He was
selected in India–Sri Lanka Youth Exchange Program 2017, organized by the
Ministry of Youth Affairs and Sports, Government of India. He was awarded DSTInternational Travel Fellowship in 2018 to visit Hawaii, USA.He is currently working on the various research projects by CSIR and DST- GOI.He has coordinated and
organized many conferences and workshops at IIITDM Kanchipuram- Chennai, IIT
Delhi, IIT Kanpur, and AIIMS Delhi. He has delivered many talks in webinars,
faculty development programs, and workshops in the institutes such as (a) BS Abdur
Rahman Crescent Institute of Science and Technology, Vandalur, Chennai, in association with Tamilnadu State Council for Science and Technology, Chennai; (b)
Sathyabama Institute of Science and Technology, Chennai; and (c) SRM University
Chennai and VIT Chennai. He have examined many MTech. and PhD students at
SRM University Chennai. He have guided more than 10 BTech, MTech, and PhD
students for their thesis.
Ashwani Kumar earned his PhD in Mechanical Engineering, specializing in
mechanical vibration and design. Currently, he is serving as a senior lecturer in
Mechanical Engineering (Gazetted Ofcer Group B) at the Technical Education
Department, Uttar Pradesh (under the Government of Uttar Pradesh) in Kanpur,
India, since December 2013. Prior to this, he held the position of assistant professor
in the Department of Mechanical Engineering at Graphic Era University, Dehradun,
India (NIRF Ranking 55), from July 2010 to November 2013. With over 13years of
extensive experience in research, academics, and administration, Dr. Kumar has
taken on various roles, including coordinator for AICTE-Extension of Approval,
nodal ofcer for PMKVY-TI Scheme (Government of India), internal coordinator
for CDTP scheme (Government of Uttar Pradesh), industry academia relation ofcer, assistant centre superintendent (ACS) in the Institute Examination Cell, and
zonal ofcer to conduct Joint Entrance Examination (JEE-Diploma), among others.
As an esteemed academician and researcher, Dr. Kumar serves as the series editor
for ve book series published by CRC Press (Taylor & Francis USA) and Wiley
Scrivener Publishing, covering topics such as advances in manufacturing, design,
computational intelligence techniques, renewable and sustainable energy developments, smart innovations and technological advancements in mechanical and materials engineering, and solar thermal energy systems. He is also a guest editor for a
special issue titled “Sustainable Buildings, Resilient Cities and Infrastructure
Systems” in Buildings (ISSN: 2075-5309, I.F. 3.8). Dr. Kumar holds the position of
editor-in-chief for the International Journal of Materials and Manufacturing and
Sustainable Technologies (IJMMST, ISSN: 2583-6625) and editor of the
International Journal of Energy Resources Applications (IJERA, ISSN: 2583-6617).
Additionally, he is a guest editor and editorial board member for 8 international
journals and serves as a review board member for 20 prestigious international journals indexed in SCI/SCIE/Scopus, including Applied Acoustics, Measurement,
JESTEC, AJSE, SV-JME, and LAJSS. With a remarkable publication record, Dr.

xxii
About the Editors
Kumar has authored/co-authored and edited over 30 books in mechanical, materials, and renewable energy engineering. He has secured three patents and is actively
involved in various research areas, including AI and ML in mechanical engineering,
smart materials and manufacturing techniques, thermal energy storage, building
efciency, renewable energy harvesting, sustainable transportation, and heavy vehicle dynamics. Recognized for his outstanding contributions, Dr. Kumar has been
awarded as the Best Teacher for excellence in academic and research. He has successfully guided 15 BTech, MTech, and PhD theses and serves as an external doctoral committee member at SRM University, New Delhi. Dr. Kumar continues to
contribute signicantly to the eld through his participation as an invited speaker,
session chair, advisory board member, review board member, and program committee member in various international conferences. His Orcid is 0000-0003-4099-935X,
and his research proles can be accessed via Google Scholar (https://scholar.google.
com/citations?hl=en&user=KOILpEkAAAAJ) and ResearchGate (https://www.
researchgate.net/prole/Ashwani- Kumar- 45).

Chapter 1
Introduction toBiotribology: AScience
ofSurface Interaction
AbhishekKumar , AvinashKumar , AshwaniKumar ,
AmitChoudhari , AshishKumarGupta , andSakibFaisal
Abstract Biotribology, the fascinating intersection of biology, materials science,
and engineering, delves into these interactions, unraveling the secrets of how biological systems minimize friction, resist wear, and adapt to their environments. This
chapter serves as an accessible introduction to the captivating world of biotribology.
It embarks on a journey through diverse biological interfaces, exploring the ingenious mechanisms employed by nature to achieve remarkable tribological feats.
From the self-lubricating joints of lobsters to the adhesive prowess of gecko feet, we
discover how these marvels inspire the development of novel biomimetic materials
and technologies. Delving deeper, we investigate the tribological challenges faced
by biological systems, such as biocompatibility, wear resistance, and lubrication
under extreme conditions. We explore how these challenges are overcome through
tailored surface structures, material properties, and ingenious biological uids. The
chapter then highlights the burgeoning eld of bioinspired tribology, where insights
from nature are harnessed to design innovative solutions for human applications.
We delve into exciting areas like biomimetic implants, self-cleaning surfaces, and
drag-reducing coatings, showcasing the immense potential of biotribology to revolutionize various elds. Finally, we ponder the future of biotribology, outlining current research frontiers and emerging trends. This chapter paves the way for further
exploration, inviting readers to join the captivating quest to understand and harness
the power of surface interactions in the biological world.
Keywords Biotribology · Surface interaction · Biomimetics · Bioinspiration ·
Lubrication · Wear · Biomaterials · Biointerfaces · Engineering
A. Kumar (*)
J.Mike Walker ’66 Department of Mechanical Engineering, Texas A&M University,
College Station, TX, USA
Department of Mechanical Engineering, University of California, Merced, Merced, CA, USA
e-mail: akumar71@tamu.edu
A. Kumar et al. (eds.), Applications of Biotribology in Biomedical Systems,
https://doi.org/10.1007/978-3-031-58327-8_1
1© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024
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