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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5881_Библиотеки_им_академика_М_И_Перельмана.pdf
X
- •Aim and Scope
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •About the Editors
- •1.1 Introduction
- •1.2.1 Friction
- •1.2.1.3 Friction Under Lubricated Conditions
- •1.7.1 Joint Tribology
- •1.7.2 Skin Tribology
- •1.7.3 Oral Tribology
- •1.8 Summary
- •References
- •2.1 Introduction
- •2.3.1 Fluid Pressurization/Fluid-Film Lubrication
- •2.3.2 Boundary Lubrication
- •2.3.3 Hydrodynamic Lubrication
- •2.3.4 Squeeze-Film Lubrication
- •2.3.5 Synovial Fluid
- •2.3.6 Hydration Lubrication
- •2.5.2 Scaffolds
- •2.5.3 Synthetic Polymer
- •2.5.4 Polyacrylamide
- •2.5.5 PEG Hydrogel
- •2.5.6 PVA Hydrogel
- •2.5.7 Double Network Hydrogel
- •2.5.8 Triple Network Hydrogel
- •2.6.1 Polyacrylamide
- •2.6.2 PEG Hydrogel
- •2.6.3 PVA Hydrogel
- •2.6.4 Double Network Hydrogel
- •2.6.5 Triple Network Hydrogel
- •2.7.1 Mechanical Properties
- •2.7.2 Structural Properties
- •2.8 Conclusion
- •References
- •3.1 Introduction
- •3.3.1 Label-Based Biosensors
- •3.3.2 Label-Free Biosensors
- •3.4 Different Nanobiosensing Techniques
- •3.4.1 Optical Sensing
- •3.4.2 Electrochemical/Electrical Sensing
- •3.4.3 Magnetic Sensing
- •3.4.4 Mass-Based Sensing
- •3.6.2 Neurodegenerative Diseases
- •3.6.3 Infectious Diseases
- •3.6.4 Metabolic Diseases
- •References
- •4.1 Introduction
- •4.2.1 Surface Functionalization
- •4.2.2 Bioconjugation
- •4.3 Synthesis Approach
- •4.3.1 Hydrothermal Method
- •4.3.2 Chemical Vapor Deposition (CVD)
- •4.3.3 Wet Chemical Method
- •4.4 Plasmonic Black Bodies (PBBs)
- •4.4.1 Gold NP (AuNPs)-Based PBB
- •4.4.2 Silver NPs (Ag NPs)-Based PBB
- •4.4.3 Platinum NPs (Pt NPs)-Based PBB
- •4.5 Biomimetic NP
- •4.6 Upconverting NP (UCNP)
- •4.6.1 Synthesis
- •4.7 Inorganic NP
- •4.7.1 Synthesis
- •4.8 Photothermal Therapy (PTT)
- •4.9 Conclusion
- •References
- •5.1 Introduction
- •5.2 Human Skin
- •5.10 Future Scope
- •5.11 Conclusion
- •References
- •6.1 Introduction
- •6.1.1 Class 1
- •6.1.2 Class 2
- •6.1.3 Class 3
- •6.4.1.1 Surface Patterning
- •6.4.1.2 Direct-Write Patterning
- •6.4.1.5 Dip-Pen Nanotechnology
- •6.4.1.7 Composing Using Beams
- •6.4.1.8 Direct Write Photolithography (DWP)
- •6.4.1.9 Light-Beam Lithography Electron
- •6.4.1.10 Focused Ion Beam Lithography
- •6.4.2 Fabrication Techniques
- •6.4.2.4 Non-invasive Glucose Monitoring Devices Technique
- •6.4.2.6 Cost-Effective Electrochemical Voltametric Sensors Techniques
- •6.4.2.7 Three-Dimensional (3D) Printing Techniques
- •6.4.2.8 UV-LED Stereolithography Printer Technique
- •6.4.2.9 4D Printing Techniques
- •6.4.2.10 Advanced Biomedical Techniques Involving Biorobots
- •References
- •7.1 Introduction
- •7.6 Mechanical Biocompatibility Challenges
- •7.7 Poor Bio-Printing Resolution
- •7.9 Limited Biomaterial Selection
- •7.11 Conclusion
- •8.2 Animal Tribology
- •8.2.1 Joint
- •8.2.3 Integumentary Change
- •References
- •8.1 Introduction
- •8.3.1 Nanotribology
- •8.4 Green Tribology
- •8.5 Conclusion
- •References
- •9.1 Introduction
- •9.2 Bio-Tribological Issues
- •9.3.2 Bone Fracture Fixation
- •9.3.4 Cardiovascular Devices
- •9.3.5 Minimal Invasive Surgical Devices
- •References
- •10.1 Introduction
- •10.2.2.1 Structural Integrity
- •10.2.2.2 Controlled Release Properties
- •10.2.2.3 Enhanced Drug Loading Capacity
- •10.2.2.4 Tailored Material Properties
- •10.2.3.1 Biocompatibility
- •10.2.3.3 Mechanical Properties
- •10.2.3.4 Drug Compatibility
- •10.2.3.5 Fabrication Compatibility
- •10.3.1 Matrix Material Properties
- •10.3.4 Biocompatibility Assessment
- •10.3.4.1 In Vitro Cell Culture Studies
- •10.3.4.2 Hemocompatibility Studies
- •10.3.4.3 In Vivo Animal Studies
- •10.3.4.4 Histological Analysis
- •10.3.4.5 Immune Response Evaluation
- •10.3.4.6 Biodegradation Assessment
- •10.4 Surface Engineering Considerations
- •10.4.2.1 Surface Coatings
- •10.4.2.2 Plasma Treatment
- •10.4.2.3 Surface Grafting
- •10.4.2.4 Dip Coating
- •10.4.2.5 Spray Coating System
- •10.4.2.6 Electrotreated Coating
- •10.4.2.9 Microfabrication Techniques
- •10.4.2.10 Surface Roughness Control
- •10.5.1.2 Mechanical Properties
- •10.5.1.3 Surface Characteristics
- •10.5.1.4 Release Kinetics Analysis
- •10.5.1.5 Biological Compatibility
- •10.5.1.7 Other Analyses
- •10.6 Advanced Fabrication Techniques
- •10.8 Conclusion
- •References
- •11.1 Introduction
- •11.2 Shape Memory Alloys (SMA)
- •11.3 Shape Memory Polymers
- •11.3.1 Heat
- •11.3.2 Light
- •11.3.3 Magnetic Field
- •11.4 Shape-Changing Hydrogels
- •11.5 Biomedical Applications
- •11.6 Conclusion
- •References
- •12.1 Introduction
- •12.3 Bioresorbable Orthopedic Implants
- •12.4.1 Polylactides
- •12.4.2 Poly (Ortho Esters)
- •12.4.3 Polyphosphoesters
- •12.4.4 Polyphosphazenes
- •12.4.5 Polycaprolactone
- •12.4.6 Polyurethanes
- •12.4.7 Polycarbonates
- •12.5.1 Compression Molding
- •12.5.2 Transfer Molding
- •12.5.3 Injection Molding
- •12.5.4 Extrusion
- •12.5.5 Blow Molding
- •12.5.6 Calendering Process
- •12.5.7 Fiber Spinning
- •12.5.8 Thermoforming
- •12.5.9 Polymer Foaming
- •12.7 Challenges
- •12.8 Conclusion
- •References
- •13.1 Introduction
- •13.3.1.1 Total Hip Replacement (THR)
- •13.3.2 Resurfacing Hip Replacement (RHR)
- •13.5.1 Adhesive Wear
- •13.5.2 Abrasive Wear
- •13.5.3 Fatigue Wear
- •13.5.4 Corrosion/Oxidative Wear
- •13.5.5 Surface Cracking
- •13.6.1 Metallic Implants
- •13.6.1.1 Stainless Steel
- •13.6.1.2 Co-Cr Alloys
- •13.6.1.3 Ti-Alloy
- •13.6.2 Ceramic Implants
- •13.6.3 Polymer Implants
- •13.6.4 Composite Implants
- •13.6.5.2 Surface Coatings
- •13.7.2.1 Hydrodynamic Lubrication
- •13.7.2.2 Boundary Lubrication
- •13.7.2.3 Elastohydrodynamic Lubrication
- •13.7.3 Biomimetic Lubrication Approaches
- •13.7.3.1 Replicating Natural Lubrication Mechanisms
- •13.7.4.1 Implant Wear
- •13.7.4.3 Synovial Fluid Degradation
- •13.8.1 Hydroxyapatite Coatings
- •13.8.1.1 Bone Integration
- •13.8.1.2 Implant Stability
- •13.8.1.4 Biocompatibility
- •13.8.2 Diamond-Like Carbon Coatings
- •13.8.3 Metal Nitride Coatings
- •13.8.4 Polymeric Coatings
- •13.8.5 Nanocomposite Coatings
- •13.9.1 Pin-on-Disk Testing
- •13.9.2 Hip Joint Simulators
- •13.9.3 Knee Joint Simulators
- •13.9.4 Tribo-Corrosion Testing
- •13.9.5 Wear Debris Analysis Techniques
- •13.9.5.1 Scanning Electron Microscopy (SEM)
- •13.9.5.2 Energy-Dispersive X-Ray Spectroscopy (EDS)
- •13.10.1.1 Tailored Geometries
- •13.10.1.2 Improved Wear Characteristics
- •13.10.1.3 Accelerated Innovation
- •13.10.2.1 Real-Time Wear Monitoring
- •13.10.2.2 Functionality Assessment
- •13.10.2.3 Implant Status Monitoring
- •13.10.2.4 Patient-Centric Healthcare
- •13.10.3.1 Advanced Biomaterials
- •13.10.3.4 Multidisciplinary Approaches
- •13.10.4.1 Wear Data Analysis
- •13.10.4.2 Predictive Wear Patterns
- •13.10.4.3 Early Intervention Strategies
- •13.10.4.4 Personalized Treatment Plans
- •13.11 Conclusion
- •References
- •14.1 Introduction
- •14.2.1 Powder Bed Fusion (PBF)
- •14.2.2 Directed Energy Deposition
- •14.3.1 Extrusion-Based AM
- •14.5 Biomanufacturing
- •14.5.1 Tissue Engineering
- •14.5.2 Organ-on-a-Chip Models
- •14.6 Conclusion
- •References
- •Index

448
Index
Drug delivery, 12, 45, 85, 96, 115, 118–126,
130, 200, 212–214, 226, 252–262,
265–267, 269, 270, 273, 274,
276–278, 282, 285, 287–298,
320, 328, 331, 333, 337,
338, 434
Drug-eluting, 253, 260, 261, 265–270, 274,
275, 277–282, 284–287, 291,
294, 298
Drug-eluting devices, 252–298
E
Elastic modulus, 39, 42, 49, 52, 57, 63, 151,
156, 158, 336, 337, 372, 376,
438, 440
Electrochemical nano-biosensor, 85, 94, 96, 97
Engineering, 4, 10, 14, 21, 151, 192, 202, 218,
219, 227, 269, 278, 288, 296,
403, 413
F
4D printing, 173, 174, 178, 185, 188, 191,
192, 320
Friction coefcients, 7, 8, 16, 39, 40, 54,
57–62, 64, 65, 93, 151, 155, 156,
158–162, 221, 238, 239, 243,
377, 388
H
Human skin, 19, 150–164
Hydrogel types, 42, 55, 63
L
Lubrication, 2, 28, 91, 150, 177, 218, 238,
269, 348
M
Manufacturing technologies, 201, 203, 434
Mechanical characteristics, 28, 30, 39, 43, 51,
52, 153, 207, 209, 210, 212, 213,
337, 439, 441
Medical devices, 14, 15, 21, 156, 163, 169,
170, 172–173, 188, 189, 191, 200,
201, 204, 212–214, 235–246, 252,
269, 315, 332, 434–437
N
Nano-biosensors, 81–105, 130
Nanocomposites, 48, 95, 97, 100, 103, 118,
121, 134, 203, 320, 377, 389, 416,
419, 441
Nanomaterials, 82–86, 90–94, 101–105,
114–116, 118, 124, 126–130, 139,
142, 183, 186, 202, 203, 213, 283,
296, 389
O
Optical nano-biosensor, 82, 83, 88, 89, 98
Orthopedics, 177, 207, 237, 242, 253, 259,
261, 315, 328–338, 354, 356, 358,
366, 367, 369, 372, 375, 376,
379–381, 383, 385–391, 402–404,
412, 413, 415–418, 435, 436
I
Implants, 2, 43, 92, 151, 169, 200, 241, 259,
315, 329, 346, 434
Infectious diseases, 97–101
Innovations, 12, 14, 116, 118, 119, 163, 171,
177, 184, 185, 188, 200, 201, 203,
207, 208, 212, 215, 378, 413–417,
438, 440
J
Joint tribology, 16–18
K
Knee and hip joints, 347, 358–365, 419
P
Photothermal therapy (PTT), 123, 125,
126, 130–142
Polymers, 12, 39, 93, 115, 151, 173, 209, 240,
256, 314, 332, 346, 439
R
Resorbable polymers, 209, 337, 439
S
Scaffolds, 30, 42–47, 99, 178, 185, 189, 191,
255, 270, 273, 290–293, 319–321,
330, 366, 367, 438, 441, 442
Shape memory alloys (SMAs), 315–316,
322, 437

Index
449
Skin tribology, 19, 150, 151, 161–164
Smart biomaterials, 213, 314–322
Smart implants, 186, 414–416, 419
Structural, 4, 9, 11, 28, 32, 42–45, 49, 63, 65,
67, 92, 93, 124, 209, 210, 253, 255,
258–261, 278–280, 282, 284, 287,
294–296, 298, 348, 352, 362, 364,
365, 375, 380, 388, 389, 436, 441
Structural properties, 29, 44, 46, 52, 54–63,
65–66, 93, 213, 256
Surface interactions, 2–21, 33, 95, 177
Surgical instrument, 243–244
T
Targeted cancer therapy, 120
3D bioprinting (3DB), 136, 183, 184
Three-dimensional (3D) printing, 173, 174,
178, 183–184, 187–189, 191,
192, 200, 201, 203, 287, 290,
330, 338, 347, 412, 414, 436,
442, 443
Tissue engineering, 28, 30, 31, 42, 45, 156,
173, 174, 210, 212, 213, 273,
291–292, 296–298, 321, 331–333,
370, 441–442
Tribological properties, 28–31, 39, 42, 52, 64,
65, 91–93, 151, 163, 238, 239, 270,
274, 279
Tribology, 12, 15, 21, 91–94, 150, 151, 154,
163, 172–173, 177, 218, 221, 224,
226–228, 236, 237, 244
W
Wear, 2, 28, 91, 150, 177, 208, 218, 236, 269,
346, 436
Wear and friction mechanisms, 346–419
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