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148
Fig. 5.37 3 grooves and 3 segments in old age. A Lid–cheek segment, B Malar segment (malar mound/malar festoon), C Nasolabial segment (with kind permission of DAEHAN medbook)
5 Filler Procedures Based ontheFacial Area
3 cm. As aging progresses, palpebromalar grooves appear on the lateral side of the infraor­bital area. Later it connects to the tear trough, which looks like a semicircular curve.
The midcheek groove is a curve that starts at the midpoint of the tear trough and the palpebromalar groove and extends inferolater­ally. It can appear as a long curve connected to a tear trough, but most seem to have two lines con­nected like the shape of a seagull’s wing. Sometimes it appears as a crease starting in the middle of the anterior cheek. It is also called an Indian band.
The three grooves above divide the anterior cheek into three segments (Fig.5.37).
• Three Grooves
– Tear trough/tear trough deformity – Palpebromalar groove (orbitomalar groove) – Midcheek groove (midcheek furrow)
• Three Segments
– Lid-cheek segment – Malar segment (malar mound/malar
festoon)
– Nasolabial segment
5.2.3.2 Tear Trough andNasojugal Groove
The denition of a tear trough varies among authors, making it difcult to dene precisely. According to the article by Nicholas T. etal., the area from the medial canthus to the mid-pupillary line is called the tear trough and from the mid­pupillary line to the lateral canthus is called the palpebromalar groove.
A tear trough is formed between the palpebral and orbital portions of the orbicularis oculi muscle and is located 2–3mm below the orbital rim. Previously, it was thought that ligaments were only present in the lateral part (palpebroma­lar groove) and not in the medial part (tear trough). However, recent anatomical studies have revealed that ligaments do exist in tear troughs. Therefore, this ligament is called the tear trough ligament (Fig.5.38).
There are several causes of tear troughs:
1. The presence of the tear trough ligament and
its sagging
2. Thin skin thickness under the eyes
5.2 Midface
Fig. 5.38 Sagittal section of medial infraorbital area
149
3. Difference in the amount of subcutaneous fat above and below based on the tear trough liga­ment. (There is more fat in the lower part, and the skin is thicker.)
4. Bulging of infraorbital fat
5. Resorption of the maxilla bone
The severity of the tear trough varies from
individual to individual.
The nasojugal groove is almost similar inloca­tion to the tear trough, which can be confusing, but it differs anatomically from the tear trough. The tear trough is formed between the palpebral and orbital portions of the orbicularis oculi mus­cle (OOm), whereas the nasojugal groove is formed between the orbital portion of the OOm and the origin of the levator labii superioris alae­que nasi muscle (LLSAN). In other words, the tear trough is located above the medial band of the orbital portion of the OOm, and the nasojugal groove is located below it. The nasojugal groove is also less pronounced than the tear trough.
5.2.3.3 Palpebromalar Groove andOrbital Retaining Ligament (ORL)
The palpebromalar groove progresses superolater­ally from the midpoint of the pupil where the tear trough terminates and aligns parallel to the infraor­bital rim. Typically, the nasojugal grooves appear rst, followed by the development of the palpebro­malar grooves. The orbital retaining ligament (ORL), a structural component, encapsulates the border of the infraorbital rim, resembling a septum. The thickness and length vary across different regions, not uniformly encircling the orbital area in a 360° manner (Fig.5.39). Notably, the ORL in the infraorbital region signicantly varies between its medial and lateral sections. Therefore, the medial section is referred to as the tear trough ligament, while the ORL is conned to the lateral part.
Medial Part (Tear Trough Ligament)
• The tear trough ligament is situated between
the palpebral and orbital portions of the orbi-
150
5 Filler Procedures Based ontheFacial Area
cularis oculi muscle. It is a robust ligament, short and rmly attached to the bone. Previously considered a ligamentous attach­ment (not an actual ligament), it is now classi­ed as a ligament.
• This ligament extends from the medial canthal tendon to the mid-pupillary line.
• The ligament shows individual variability in terms of sagging and asymmetry on both sides.
Lateral Part (Orbital Retaining Ligament,ORL)
• The orbitomalar ligament is a more relaxed and elongated ligament, not as rmly attached to the bone, creating a space between the orbital bone and the orbicularis oculi muscle. This space facilitates easier ller injection compared to the medial part.
• It is also easier to create space for ller injec­tion and to relax the ligament for injection in this area compared to the medial part.
• Lateral hooding often occurs due to the laxity of the orbitomalar ligament.
5.2.3.4 Midcheek Groove andZygomatico-cutaneous Ligament
The midcheek groove initiates where the tear trough and palpebromalar groove meet, extending inferolaterally. It appears connected to the tear trough, but the zygomatico-cutaneous ligament (Z-C ligament) begins where this connection seems unnatural. The Z-C ligament is attached from the maxilla extending to the zygomatic bone, resulting in a midcheek groove forming a long, band-like brous region along this ligament within the anterior cheek (Fig.5.39). The region inated with malar fat between the midcheek and palpe­bromalar grooves is known as the “malar mound.” Both the tear trough and midcheek groove coin­cide with the superior border of the malar fat pad. Based on the Z-C ligament, supercial and deep malar fats are segmented into upper and deeper sections. As aging progresses, the deep medial cheek fat (DMCF) beneath the Z-C ligament con­tracts and depresses, while the supercial fat (such as nasolabial and medial cheek fat) sags.
Fig. 5.39 Sagittal section of lateral infraorbital area. Green dotted line: Tear trough ligament, yellow dotted line: Palpebromalar groove, red dotted line: Midcheek groove(Indian band). SOOF: Suborbicularis Oculi Fat.
Layers from super cial to deep: skin, super cial fat (malar fat), orbicularis oculi muscle, SOOF (Suborbicularis Oculi Fat)
5.2 Midface
151
Conversely, the supercial and deep malar fat pads above the Z-C ligament are supported by the liga­ment, forming a distinct top/bottom boundary based on the Z-C ligament.
5.2.3.5 Orbital Fat, SOOF (Suborbicularis Oculi Fat), andMalar Fat
Orbital Fat
Orbital fat is present in both infraorbital and supraorbital regions. Both infraorbital and supra­orbital fat are enclosed by orbital septa and extend outward (fat-orbicularis oculi muscle­skin). Herniation of infraorbital fat is one of the causes of the formation of tear troughs and palpe­bromalar grooves (Fig.5.38).
Suborbicularis Oculi Fat (SOOF)
The deep fat under the orbicularis oculi muscle (OOm) beneath the eye is called suborbicularis oculi fat (SOOF), and the deep fat under the OOm above the eye is termed retro-orbicularis oculi fat (ROOF). As age progresses, the volume of SOOF and deep medial cheek fat decreases (Fig.5.39). This leads to a reduction in the vol­ume of the anterior cheek and the appearance of infraorbital hollowness.
SOOF provides a suitable space for injecting llers to correct infraorbital hollowness. Although the angular vein passes through this SOOF space before coursing along the medial border of the orbicularis oculi muscle, it can be safely injected deep into the prezygomatic space.
The SOOF is divided into medial and lateral parts. The innermost part of the tear trough has tight muscles and no SOOF, making it fundamen­tally impossible to correctly inject ller into the fat layer below the innermost OOm. A small amount is injected medially, and sufcient vol­ume is created by injecting enough ller laterally. If the groove is not adequately corrected on the inner side, undermine below the skin and inject the ller with low viscosity to complete the correction.
Malar Fat
The fat deeper than the orbicularis oculi muscle (OOm) under the eye is divided into superior and
inferior fat based on the tear trough ligament and orbitomalar ligament. The fat in the superior (cra­nial) part is infraorbital fat, and the fat in the infe­rior (caudal) part is the suborbicularis oculi fat (SOOF).
The supercial fat over the OOm, which is inferior (caudal) based on the tear trough liga­ment, is malar fat. That is, both the tear trough and palpebromalar grooves coincide with the superior border of the malar fat pad (Fig.5.39). The fat more medial than the malar fat is super­cial medial cheek fat and nasolabial fat. Malar fat is divided into superior and inferior parts based on the zygomatico-cutaneous ligament to form midcheek grooves. The bulging of malar fat between the midcheek groove and the palpebro­malar groove is termed the malar mound.
5.2.4 Dark Circle (Tear Trough
andPalpebromalar Groove)
Dark circles are primarily caused by three fac­tors: color change, contour change, and skin lax­ity. Treatment varies depending on the cause. Various methods such as laser treatment, fat transfer, llers, transconjunctival blepharoplasty, HIFU, and radiofrequency are available. One of the cases that can be resolved by ller injection is the change of contour under the eye. As aging progresses, dark circles develop as the infraor­bital fat starts to bulge, fat volume decreases, and bone resorption occurs. Upon close examination of dark circles, not only changes in color but also changes in contour or skin laxity can be observed.
In this chapter, we will discuss ller treatment for tear troughs and palpebromalar grooves caused by the anatomical structures mentioned in the previous chapter.
5.2.4.1 Design
Since the cause of dark circles is due to structural differences in the submuscular plane, correction of deeper layers should also be considered.
There are some precautions to be taken in the design process and while checking results with the patient. When designing before the proce­dure, it is advisable to check the area in a mirror
152
5 Filler Procedures Based ontheFacial Area
with the patient. It is important to check exactly where the patient wants to be corrected: tear trough, palpebromalar groove, or midcheek groove. This is because the patient usually wants to correct the infraorbital hollowness and some­times claims that the desired area has not been corrected after the procedure. After correction of tear trough, the nal assessment should be checked with the patient gazing straight ahead. In general, the tear trough looks more severe when looking upward than gazing ahead and less severe when looking down. Therefore, it is advisable to correct the tear trough based on the patient gaz­ing straight ahead. When a patient looks in the mirror after the procedure, they tend to check by looking up at the eyes. When the patient looks upward, the tear trough appears to be more severe, and the patient tends to think that it is not corrected. In other words, if the patient looks upward, the result appears undercorrected. If the patient looks downward, the result appears over­corrected. Therefore, it is desirable to check the treatment area by gazing at front in a mirror and to explain that it may look slightly different depending on the angle of view and lighting.
5.2.4.2 Anesthesia
Infraorbital nerve block simplies the procedure execution. Although it’s possible to use local anes­thetic creams, cold anesthesia, and lidocaine­infused llers without a nerve block, the patient may experience pain depending on the depth of the injection. It’s recommended to perform an infraor­bital nerve block rst when injecting into the deep layer. For supercial injections, the procedure can be performed using only topical anesthesia.
5.2.4.3 Choice ofFiller
It is advisable to avoid llers with low viscoelas­ticity when injecting into the deep layer, i.e., the prezygomatic space. If the skin is thin and the amount of fat (SOOF/malar fat) is small, the overall thickness of the soft tissue is thin, so ll­ers with medium viscoelasticity are recom­mended. In such cases, using a high viscoelastic ller may cause the shape to appear unnatural and bulge out. Conversely, if the skin is thick and the amount of fat is large, the volume increase
may appear too modest after injection with a medium viscoelastic ller. In this case, it is advis­able to use a high viscoelastic ller.
When injecting into supercial layers, llers with the lowest viscoelasticity and minimal water retention capacity should be used. Choose a ller that molds well after the procedure and retains its shape. Since llers with high water retention capacity may cause edema post-procedure, spe­cial care should be taken not to overcorrect if the skin is thin. To prevent edema and achieve suf­ciently corrected results during supercial injec­tion, it is advisable to complete the nal procedure with a secondary treatment after a certain period following the rst procedure.
5.2.4.4 Injection Technique
Tear Trough
When correcting the tear trough, the injection depth can be chosen from (1) deep, (2) super­cial, and (3) deep + supercial. The author pre­fers (3) deep + supercial for primary correction and (2) supercial for secondary treatments.
Based on the pattern of sagging of the tear trough, you can choose from the three methods above. Deep injection is required if there is a lack of volume in the anterior cheek. Typically, when the tear trough ligament is tightly attached, caus­ing the skin to be deeply recessed, deep injection alone does not improve the condition and super­cial injection is necessary. It is also essential to perform ligament release before injecting the ller.
Asymmetry may occasionally be present on both sides of the tear trough, so it should be assessed prior to the procedure. This may be due to differences in the attachment point or length of the ligament below the orbital rim. Taking these differences into consideration, varying the vol­ume and depth of ller injection accordingly is recommended for effective correction.
If the medial border of the orbicularis oculi muscle (OOm) is band-like on one or both sides, wrinkles may become visible during smiling or frowning. Patients may not notice this before ller treatment, but may discover it days after the procedure and express dissatisfaction with asym­metry during facial expressions. Therefore, it is
5.2 Midface
153
essential to ask the patient to frown during the assessment to check for any prominent medial bands of the OOm and inform the patient in advance. For correcting the medial band of the OOm, supercial ller injection alone is not suf­cient—combination treatment with botulinum toxin is necessary.
The entry point is placed along the extension of the tear trough, approximately 1–2cm away from the end of the groove to be corrected (Fig.5.40). The cannula is inserted at a 45–60° angle through the entry point. After reaching the bone, it is advanced along the prezygomatic space of the SOOF layer (Fig.5.41), entering just beneath the tear trough. Then, ller is injected slowly using a retrograde technique. Since the available space for injection in the medial portion is very limited, only a small amount should be injected while checking for visible volume eleva­tion at the midpoint (Fig.5.42).
Because deep-layer injection alone may not sufciently correct the medial portion of the tear trough ligament, the cannula should be reposi­tioned to a more supercial plane above the orbi­cularis oculi muscle, and then ller should again be injected slowly using the retrograde technique (Fig. 5.43). Low-viscosity llers are injected
with a 25G cannula. Before injecting into the supercial layer, it is important to rst tunnel the area beneath the skin. Slightly wider tunneling than the actual injection area is key. This allows the ller to spread into the adjacent area rather than bulging under the thin skin, resulting in a more natural contour. If the medial tear trough is sufciently long or relatively loose, deep layer injection alone may be sufcient for correction.
Palpebromalar Groove
The palpebromalar groove can be partially improved by the volume effect after correcting the tear trough or midcheek groove rst. This is because during the tear trough correction, the volume is somewhat lled by deep injection. However, if the volume decreases and additional deep injection is needed in this area, inject ller into the submuscular plane.
Special attention should be given to vascular damage when treating this area. Since visible supercial veins (especially the inferior palpebral vein) are more developed on the lateral than the medial aspect of the infraorbital area, it is advis­able to visually check the veins and avoid them before making the entry point.
a
Fig. 5.40 Location of entry point and injection space for tear trough correction. (a) Cannula at the entry point. (b) Cannula is located under the tear trough while injecting ller into deep layer
b
154
Fig. 5.41 Deep injection and supercial injection for tear trough correction (transverse view). (a) Blue area – deep injection. (b) Pink area – supercial injection
5 Filler Procedures Based ontheFacial Area
5.2.4.5 Side Eects andPrecautions
• Combination Treatments for Dark Circles: If llers alone cannot resolve dark circles, it’s crucial to thoroughly explain to the patient that additional combination treatments may be necessary. Surgical intervention might be required in cases of severe infraorbital fat pro­trusion. Surgical treatments may prove more effective than ller injections, particularly for patients aged 50–60 and older. For those with pigmentation under the eyes, a combination with laser therapy is necessary.
• Vessels to Avoid During Injection: Over 30% of Koreans have an infraorbital branch of the duplex type facial artery, known as the “detoured branch of the facial artery.” The angular vein has a large diameter, especially
when dilated in the supine position. Both these vessels (infraorbital branch of the duplex type facial artery and angular vein) pass through the SOOF and DMCF and then ascend along the medial border of the orbicularis oculi mus­cle (Fig.5.44). Injection with a needle has a higher likelihood of causing vascular damage, hence the strong recommendation to use a cannula. Even with cannula use, careful han­dling is required to avoid damage to the vessels.
• Nodularity: Injecting more supercially than the orbicularis oculi muscle can cause prob­lems in the following situations: (1) uneven injection of ller, (2) excessive volume of injection, (3) injection of high viscoelastic ll­ers, and (4) injection of llers with high water retention capacity.
5.2 Midface
155
a
b
c
Fig. 5.42 Deep injection for tear trough correction. (a) Insert cannula under the tear trough. (b) Check if the can­nula is located in a deep layer not a supercial layer.
a
Fig. 5.43 Comparison of depth of cannula during deep injection and supercial injection for tear trough correc­tion. (a) Deep injection – cannula is placed under the
(c) Inject ller and feel the resistance over the treatment area with ngertips on the opposite hand
b
muscle so that skin is not inuenced by its movement. (b) Supercial injection – skin is lifted and motion of cannula is visible when cannula is lifted and moved
156
Fig. 5.44 Running of detoured branch of facial artery and angular vein (deep fat layer) / (with kind permission of MANIAMIND)
5 Filler Procedures Based ontheFacial Area
• Overcorrection: Injecting too much volume into both deep and supercial layers can appear unnatural and blur the boundaries with the pre-tarsal fullness. Since the tear trough is dense tissue on the medial side and is not suf­ciently released, injecting large amounts into deep layers can make dark circles appear more pronounced. Therefore, it is advisable to use the sandwich technique, where a small amount is injected into the deep layer of the tear trough, followed by a supercial injection.

5.2.5 Midcheek Groove

5.2.5.1 Causes andAnatomy
The midcheek groove can develop due to several factors.
Firstly, changes in fat around the zygomatic-
cutaneous ligament (Z-C ligament) are the pri­mary cause. As discussed in Sect. 5.2.3, with aging, the volume of the deep medial cheek fat (DMCF) beneath the Z-C ligament decreases more compared to the deep fat above the Z-C ligament, creating a top/bottom boundary based on the Z-C ligament.
Secondly, bone resorption of the maxilla
results in volume loss of the anterior cheek.
Thirdly, sagging of the Z-C ligament leads to
the prominence of the malar mound.
The treatment method varies depending on the
causes. Anatomical causes are rst examined, followed by the appropriate treatment. Among
these treatments, there are two methods to treat with llers, and the choice of anesthesia, injec­tion method, and ller varies depending on the depth of injection.
5.2.5.2 Treatment
Supercial Injection
Before injecting the ller, it is benecial to rst use a cannula to tunnel the brous tissue at the reticular dermis level of the zygomatic-cutaneous ligament (Z-C ligament). While holding the skin still with the other hand, move the cannula. Repeat this process about 10 times using a 23G cannula and inject the ller once the movement of the cannula has softened. Too much damage to the tissue during the tunneling process can increase the risk of bruising and swelling, so gen­tle handling is necessary to minimize tissue injury. A medium viscoelastic ller is typically injected in this area. In patients with sufcient volume in the anterior cheek, supercial injection alone may be sufcient for correction.
Deep Injection
If there is insufcient volume in the anterior cheek, supercial injection alone will not resolve the issue. In such cases, deep injection alone can have an excellent correction effect and high patient satisfaction. There are two methods for deep injection—using either a cannula or a needle.
First, use medium to high viscoelastic llers.
Inject the ller using a needle at the supraperios-
5.2 Midface
Fig. 5.45 Deep injection and supercial injection for midcheek groove correction. (a) Blue area – deep injec-
tion. (b) Pink area – supercial injection
teal level, and move up to the middle layer using the towering technique. The injection position of the needle is crucial, and make sure to inject directly beneath the Z-C ligament. As aging pro­gresses, the volume of the SOOF and DMCF located directly below the Z-C ligament decreases. Filling the volume loss by injecting ller results in lifting of the sagging Z-C ligament and improv­ing the midcheek groove (Fig.5.45).
The second method involves using a cannula. For deep injections, it is recommended to rst
ll the volume under the tear trough with a can­nula and then correct underneath the Z-C liga­ment. In the treatment of the midcheek groove, deep injection alone provides excellent correc­tion, but if the patient desires detailed correction, additional injection to the supercial layer is recommended.
Reduction of Malar Fat
When the midcheek groove is caused by malar fat bulging, or patients who refuse llers need treat­ment, a different approach should be taken. As explained in the rst part of the chapter, the DMCF below the Z-C ligament decreases more in volume compared to the deep fat above the ZC ligament. Reduction of the fat above the Z-C lig­ament decreases the difference in fat volume
157
above and below the Z-C ligament, improving the midcheek groove. A lipolytic agent and HIFU can be used to reduce the malar mound volume above the Z-C ligament. However, since the cor­rection is not as detailed as with llers, it should only be applied to patients who are not keen on llers, and the physician must explain in advance that it will not be an ideal correction.
5.2.6 Anteromedial, Buccal, andLateral Cheek Hollow
Pre-procedural Considerations
When referring to sunken cheeks, there are ethnic differences based on differences in facial bone structure. Typically, Koreans dene sunken cheeks as either lateral cheek hollow (hollowness in the area inferior to the zygomatic arch) or buc­cal cheek hollow (hollowness in the perioral region). In contrast, Caucasians refer to hollow­ness in the maxillary region across the anterome­dial cheek (midcheek) and zygoma or volume loss needing malar augmentation as sunken cheeks.
When creating “apple cheeks” by augmenta­tion of the malar eminence, the preferred loca­tions and shapes of the apple cheek differ among Caucasians and Asians. Caucasians prefer to have the apex of the cheek to be lateral to or above the cheekbone, whereas Asians, who have wider mid­faces with more prominent cheekbones, prefer the apex to be located more medially.
Prior to ller administration, the central point of the cheekbone should be located. In Asians, this point can be located by drawing a horizontal line from the lower portion of the alar groove to the root of the helix and a vertical line from the lateral canthus to the lateral commissure. The apex should be located close to the intersection of the two lines or slightly medial to this point. Unlike in Westerners who request prominent augmentation of the cheeks, the anterior malar area should be injected just enough to observe a smooth mound that occurs when the smiling action elevates the cheek fat pad (Fig.5.46).