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Deep t
Stained gelatin
ry
3.5 Identication ofSubSMAS Spaces oftheFace forFiller Injection: Cadaver Studies Using Stained Gelatin
Superficial temporal arte
emporal fascia
Superficial temporal fascia
Fig. 3.15 Gelatin in the space between supercial and deep temporal fascia
77
cle. However, targeting deep to the temporalis muscle is inefcient. In the deeper layer, a larger amount of ller is needed to create volume so the treatment effect when compared to volume of ller used is low. Another problem is that the movement of the injected ller occurs due to the strong contraction of the temporalis muscle that occurs when chewing, and the physical proper­ties of the ller change due to continuous stimu­lation, so the actual effect is not efcient compared to the hardness with the amount of the injected ller.
Generally, with sunken temples, the depres­sion is located in the lower temporal region immediately above the zygomatic arch. Of the two temporal fat pads located in this region, the supercial temporal fat pad located between the supercial and deep layers of the deep temporal fascia should be targeted. Compared to injecting deep to the muscle, efcient volumization of the sunken area above the zygomatic arch can be attained with a smaller amount of ller.
Contrary to the belief that it’s technically dif­cult to inject ller into the supercial temporal fat pad, over time, physicians will be able to easily identify the loose sensation of the supercial tem­poral fat pad. The cannula will penetrate the supercial temporal fascia, followed by the rmer
supercial layer of the deep temporal fascia before reaching the supercial temporal fat pad. Further insertion of the cannula will be eventually impeded by very rm deep layer of the deep tem­poral fascia. It is recommended that the physi­cians have accurately identied the layers of the temple before attempting to inject this region.
As shown in Fig. 3.16, the cadaveric study showed that gelatin could be injected accurately into the desired supercial temporal fat pad.
Within the two layers of the deep temporal fascia, the middle temporal vein traverses in the upper portion of the supercial temporal fat pad, and its course is parallel to the zygomatic arch. The sentinel vein traverses the temporal region perpendicularly and joins the middle temporal vein (Fig.3.15-5, right). Good understanding of the vascular anatomy of the supercial temporal fat pad reduces concerns regarding vessel injury (Fig.3.17).
After conrmation of placement of the gelatin in the supercial temporal fat pad, the deep layer of the deep temporal fascia was removed to eval­uate the deeper structures. Deep to the supercial temporal fat pad are the deep temporal fat pad (also known as the superior lobe or temporal extension of the buccal fat) and the temporalis muscle (Fig.3.18).
78
Superficial temporal fat padStained gelatin
of deep temporal fascia
Superf
Middle temporal vein Sentinel vein
3 Anatomical Considerations forFiller Procedures
Superficial temporal fasciaSuperficial layer
Fig. 3.16 Gelatin in supercial temporal fat pad
Fig. 3.17 Middle
temporal vein and sentinel vein
Superficial layer of deep temporal fascia
Stained gelatin
icial temporal fat pad
Superficial layer of deep temporal fascia
Deep la te
Superficial temporal fat pad
Pr
us space
3.5 Identication ofSubSMAS Spaces oftheFace forFiller Injection: Cadaver Studies Using Stained Gelatin
79
yer of deep
mporal fascia
Fig. 3.18 Deep temporal fat pad under deep temporal fascia
Fig. 3.19 Subprocerus
space of the nose
Superficial layer of deep temporal fascia
ocerus muscle
3.5.3 Subprocerus andSubnasalis Space
Deep temporal fat pad
Deep layer of deep temporal fascia
Subprocer
the bromuscular layer, allowing ller proce­dures for both supercial and deep layers.
However, the distal part, including the tip of the The soft tissue layer of the nose including the skin consists of ve layers from above: the skin; subcutaneous fat layer; bromuscular fat layer, which is connected to SMAS and includes nasa­lis muscle in the nasal bridge and procerus mus­cle in the nasal root area; submuscular fat layer; and nasal bone and cartilage layer.The proximal part of the nose, including the nasal root, has dynamic properties, so there is a space for the upper and lower layers to move smoothly around
nose, centered on the scroll area, the boundary
between the late nasal cartilage and the alar carti-
lage, has a bromuscular layer attached to the
skin tight because the subcutaneous fat layer con-
sists of dense collagen ber and fat cell.
Therefore, it is recommended to apply ller pro-
cedures to the subprocerus space of Fig.3.19 and
the subnasalis space of Fig. 3.20, which are
spaces under the muscles, when safely trying to
augment the volume.
80
Nasalis muscle
Subnasalis space
Orbicularis oculi muscle
Orbicularis ocli muscle
Fig. 3.20 Subnasalis space of the nose
3 Anatomical Considerations forFiller Procedures
Fig. 3.21 ROOF under orbicularis oculi muscle
During the procedure, we should hold and lift the skin thickly so that procerus muscle or nasalis muscle under the subcutaneous tissue layer is sufciently included and then inject the ller deeply under the muscle.
3.5.4 Preseptal Space ofUpper
For sunken eyelid correction, ller is injected to replace lost fat volume. Passing through the orbital septum to inject into the septal fat is asso­ciated with vascular injury/bleeding and levator muscle injury. The levator muscle passes poste­rior to the septal fat and is the muscle responsible for opening the eyes.
Eyelid
Stained elatin over orbital septum
ROOF under eyebrow region
Another potential target is the deep fat layer superior to the septum and is in the same plane as the retro-orbicularis oculi fat (ROOF, deep fat layer deep to the eyebrow). However, in case of sunken eyelid, this deep fat layer has atrophied signicantly and may be difcult to inject ller.
The preseptal space is an ideal target. Volumization with minimal risk of injury to the major neurovascular structures such as the supra­orbital artery and nerve and the palpebral vascu­lar arcade is possible in this space. The preseptal space is the space in between the orbicularis oculi muscle (SMAS of the midface) and the septal wall (deep to the orbicularis oculi muscle).
As shown in the left photo in Fig.3.21, when the cadaveric skin and subcutaneous fat tissue were removed to examine the orbicularis oculi
under orbicularis oculi muscle
3.5 Identication ofSubSMAS Spaces oftheFace forFiller Injection: Cadaver Studies Using Stained Gelatin
81
muscle, the gelatin present within the preseptal space was not visible. When the muscle was lifted, as shown in the right photo in Fig.3.21, the gelatin that had been placed along the ROOF and orbital rim margin below could be identied. Further dissection revealed gelatin that was placed accurately into the preseptal space above the septum.
3.5.5 Suborbicularis Space ofTear Trough
The tear trough deformity forms in the medial orbit, along the medial canthus to the midpupil­lary line. Deep to the orbicularis oculi muscle in the medial orbital region, there is no suborbicu­laris oculi fat tissue. Therefore, the subSMAS space can be viewed as the space between the orbicularis oculi muscle (SMAS) and perios­teum. The at orbicularis oculi muscle band is rmly attached to the orbital bone, and sufcient space may not be made. It can be seen that the injected gelatin was found not only deep to the muscle but also within the muscle.
The left picture of Fig.3.22 shows only the muscles, and the gelatin injected under the mus­cles is not well visible, but as shown in the right picture of Fig.3.22, the dyed gelatin is clearly visible.

3.5.6 Prezygomatic Space

For patients with a at appearance due to sunken anterior cheeks, ller can be injected to create round “apple cheeks.” As Caucasians experience bone volume loss with aging, ller injection in the periosteal layer immediately above the bone is generally recommended. In contrast, excluding patients who congenitally have underdeveloped cheekbones, most Koreans have at anterior cheeks due to the loss of soft tissue volume above the bone that occurs with age, rather than bone volume loss. Therefore, Koreans require a proce­dure that augments volume in this soft tissue area.
Unlike the forehead or the lower face, the mid­face has well-developed supercial and deep fat compartments, which are supercial and deep to the SMAS layer, respectively. For mild to moder­ate volume loss, ller is injected deep to the SMAS into the deep fat layer. For more severe volume loss, ller is injected into the prezygo­matic space located between the deep fat layer and the periosteum. There are no importance neurovascular structures in the prezygomatic space making it a safe injection zone.
The prezygomatic space is usually formed above the body of the zygoma. The oor is the origin of the zygomaticus muscle, the roof is the orbicularis oculi muscle line, the upper border is
Orbicularis oculi muscle
Fig. 3.22 Gelatin under orbicularis oculi muscle in tear trough region
Stained gelatin
82
Orbicular
Deep fat layer
Stained gelatin
premaxillary space
3 Anatomical Considerations forFiller Procedures
the orbicularis retaining ligament, and the lower border is the zygomatico-cutaneous ligament. The prezygomatic space is connected to the lower temporal space in the temporal region through the temporal tunnel.
This space could be divided into the seven lay-
ers (supercial to deep) (Table3.3).
In the cadaver picture, as described above, dyed gelatin in the prezygomatic space of the malar region corresponding to the preperiosteal space present on the bone can be seen that the fat in this space is whiter and more loose, unlike the yellow SOOF at the top (Fig.3.23).
3.5.7 Premaxillary andRistow’s
Space
The premaxillary space is a space that forms between the zygomatico-cutaneous ligament and the buccal portion of the maxillary ligament or between the angular artery (extension of the facial artery and runs along the side of the nose) and angular vein (extension of the facial vein that runs along the nasojugal groove). Like the prezy-
gomatic space, Ristow’s space is also a space between the deep fat layer and the periosteum (Fig.3.24).
When paranasal depression due to depressed canine fossa is present, Ristow’s space targeted for the procedure is within the same midface plane, and it is created between medial part of the deep medial cheek fat and the periosteum. The presence of gelatin in Ristow’s space in the para­nasal region of the nasolabial fold was conrmed (Fig.3.25).
Since the premaxillary space and Ristow’s space are on the same plane, the ller placed under the wrinkle line to correct the nasolabial fold can move across the wrinkle line to the top of the wrinkle line. Therefore, when performing a ller procedure on a paransasal region, it is nec­essary to press the upper part of the nasolabial crease with a non-treatment nger to prevent the ller from moving to the upper part of the wrin­kle line.
3.5.8 Preparotid andPremasseteric
Space
Table 3.3 Seven layers of prezygomatic space
1. Skin
2. Subcutaneous fat layer
3. Orbicularis oculi muscle
4. SOOF (Sub-Orbicularis Oculi Fat)
5. Deep fascia origin of zygomatic muscles
6. Preperiosteal (prezygomatic) fat layer
7. Periosteum
is oculi muscle
Fig. 3.23 Gelatin in prezygomatic space
The lateral zygomatic bone and zygomatic arch tend to show greater protrusion among Asians than Caucasians, and as a result, the lateral cheek hollow below the zygomatic arch appears more prominent than it actually is. Prominent lateral
Stained gelatin in
Fig. 3.24 Gelatin in premaxillary space
Deep fat layer
Deep fat layer
ligaments
3.5 Identication ofSubSMAS Spaces oftheFace forFiller Injection: Cadaver Studies Using Stained Gelatin
Fig. 3.25 Gelatin in Ristow’s space on paranasal region
Stained gelatin in Ristow’s space
Fig. 3.26 Zygomatic ligaments on lateral cheek and zygomatico­cutaneous ligaments on anterior malar region
83
cheek hollow is due to the zygomatic ligament, which is one of the most powerful retaining liga­ments in the face. The hollowness is not associ­ated with weight loss but due to the zygomatic ligament, parotid-masseteric ligament (below the zygomatic ligament), and ligaments that cover the platysma. These structures pull on the skin to make this area look at and hollow (Fig.3.26).
In such cases, ller injection into the subcuta­neous fat will not correct the hollowness. Injection into an incorrect plane may lead to wid­ening of the lateral area or hardening of the region
Zygomatic ligaments Zygomatico-cutaneous
where the ller has been implanted instead of correcting the cheek hollowness. Filler must be injected into the deeper layers of the preparotid and premasseteric space. The preparotid and pre­masseteric space is the region superior to the parotid gland covering the superior half of the masseter muscle and the lower half of the mas­seter muscle.
Like the upper and lower temporal spaces above the deep fascia of the temporalis, the prep­arotid and premasseteric spaces are also located above the deep fascia of the masseter muscle which is mastication muscle.
84
3 Anatomical Considerations forFiller Procedures
The preparotid and premasseteric spaces are
bounded by the following structures (Table3.4).
The Stenson’s duct exiting from the parotid gland and buccal branch of the facial nerve are located deep to the parotid-masseteric fascia (deep fascia). This space between the supercial and deep fascia is therefore a safe layer to per­form various procedures. Anterior to the bound­ary between the lateral and anterior face is where the facial nerve beings to descend from the plane close to the SMAS into the deeper layers. Therefore, anterior to this boundary, deep injec­tion requires caution (Fig.3.27).
Table 3.4 Boundary of preparotid and premasseteric space
1. The oor—Parotid gland and the lower half of masseter muscle
2. The roof—SMAS and platysma muscle
3. The posterior border—The anterior edge of strong platysma—auricular ligament
4. The anterior border—The masseteric ligaments near the anterior edge of masseter muscle
Just as in correcting the midcheek groove, in lateral cheek hollow treatment, space must be obtained via partial tunneling of the areas between the zygomatic ligaments attached along the zygomatic arch and the masseteric-cutaneous ligament below it to allow the ller to spread through the ligaments. After creating the space, injecting the ller into the preparotid and pre­masseteric space between the SMAS and parotid­masseteric fascia Fig.3.28 can result in a smooth and sufciently volumized cheek area without irregular borders of the implanted ller (Fig.3.29).

3.5.9 Prebuccal Space

In the buccal area, ller can be injected in the buccal space (contains buccal fat) and the prebuc­cal space, which is lateral to the buccal space.
The buccal space is one of the deep fascial spaces, and like the submandibular space (con­tains submandibular gland), the buccal space is
Fig. 3.27 Anatomical structures between the compartments of preparotid and premasseteric space
SMAS layer
Parotid gland
Stained gelatin
3.5 Identication ofSubSMAS Spaces oftheFace forFiller Injection: Cadaver Studies Using Stained Gelatin
Fig. 3.28 Gelatin in preparotid and premasseteric space
Fig. 3.29 Before and
after treatment of lateral cheek hollowness
85
deep to the deep fascia. The buccal space and the buccal fat within this space allow smooth move­ment of the overlying nasolabial segment of the midcheek and serve as a buffer against excessive motions of jaw movement. Buccal fat covers a much wider area than previously believed, span­ning from the area above the mandible to the tem­poral region. It is divided into superior, middle, and inferior lobes, with each lobe separated as capsules. Generally, it is the inferior lobe that is referred to as the buccal fat pad (Fig.3.30).
The buccal space where the buccal fat pad is located is an anatomically safe zone. The parotid duct runs supercial to the buccal space (between the middle and inferior lobes), and the marginal mandibular branch of facial and nerve runs along the oor of the buccal space, always passing across the mandible below the inferior lobe. When young, the buccal space is located superior to the oral commissure and medial to the anterior border of the masseter muscle. The space expands with age and the buccal fat prolapses below the
86
Stained gelatin
Fig. 3.30 Extensions of buccal fat
3 Anatomical Considerations forFiller Procedures
Superior lobe (Temporal extension of buccal fat)
Middle lobe
Inferior lobe (Buccal fat pad)
Table 3.5 Boundary of buccal space
1. The oor—The buccinator muscle
2. The roof—Mimetic muscles and the SMAS
3. The superior boundary—The maxillary ligament
4. The inferior boundary—Loose adhesion of the platysma muscle
5. The anterior boundary—The modiolus
6. The posterior boundary—The facial vein and the masseteric ligaments
level of the oral commissure to the anterior bor­der of the inferior portion of the masseter muscle, causing exacerbation of marionette line and jowl. The buccal space itself is located in the midface, below the medial and lateral part of the deep medial cheek fat in the midface, and its boundar­ies are described in Table3.5.
In cases with buccal cheek hollow, volumizing the thin capsule of the buccal fat pad may result in an undesirable effect of mouth protrusion and not the intended volumization of the lateral area. Targeting the following spaces will result in effective volumization with a smaller amount of ller: capsule that surrounds the buccal fat pad and forms part of the buccal space and prebuccal space between the SMAS that covers the afore­mentioned capsule. The buccal branch of the facial nerve that runs above the buccal fat pad is usually encapsulated, and thus, there is no con-
Buccal fat region
Fig. 3.31 Gelatin in prebuccal space
cern for major injuries, unless the area is pene­trated by a large bore needle.
The presence of gelatin in the prebuccal space between the capsule surrounding the buccal fat pad and the SMAS was conrmed (Fig.3.31).
3.5.10 Subdepressor Anguli Oris
Space
If the supercial brous layers of the orbicularis oris muscle and depressor anguli oris muscle, which are the most supercial of the muscles forming Modiolus, have a wide height difference from the deep brous layer of orbicularis oris muscle, a commissural line made vertically