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178
A. Kate and S. Basu
chamber using the van Herick grading system can help screen patients with angle closure disease [15].
(e) Iris: Focal illumination using a slit beam
of varying width helps evaluate the iris pattern and color. Changes in the contour may indicate a local mass lesion, which will not be visible unless a thin slit is used. Similarly, a very high magnication is needed to rule out the presence of neo­vascularization around the pupillary area. Retro-illumination can identify focal areas of thinning of the iris tissue, which will transmit the reected light.
(f) Lens examination uses an optical section
where the illumination angle is usually greater than the one used for examining the cornea. Similar to the examination of the cornea, it is imperative to rst exam­ine with a wider slit to detect the presence of small alterations such as glaucom­ecken, early posterior subcapsular cata­racts, etc. Retro-illumination is perhaps a more sensitive technique for detecting early focal lenticular changes; it must be employed during routine lens examina­tion with the pupil dilated.
(g) Anterior vitreous: Examination of the
anterior vitreous is similar to the exami­nation of the anterior chamber. It is done using direct illumination with a moder­ately wide slit beam. Unlike the anterior chamber, the vitreous cavity is not optically clear and has a strand-like appearance that moves with the eyeball's movement. Using a conical light beam helps identify the presence of oating cells, dispersed vitreous hemorrhage, etc.
14.7 Slit Lamps Accessories
This section will discuss different accessories. When used, the utility of the slit lamp can extend beyond the examination of the anterior segment and the vitreous cavity.
1. Goldmann applanation tonometer: This instrument is attached either on the side of the slit lamp or superiorly and is swiveled into place when required. It consists of a prism­holding unit, a sensor arm, and a metal house for weights [16, 17]. The prism-holding unit is shaped as a truncated cone with a surface area of 7.35mm2 and a diameter of 3.06mm [16, 17]. It houses a doubling prism which breaks the circular meniscus and needs realignment to measure the intraocular pres­sure (IOP). The Goldmann applanation tonometer is the current gold standard for measuring IOP (see Chap. 17 for further details).
2. Lenses: Several handheld contact and non­contact lenses can augment slit lamp exami­nation. These include lenses for viewing angles, such as the Goldman, Posner, and Sussman lenses. Fundus evaluation with a slit lamp biomicroscope requires a +90D or +78D lens. The distance between the lens and the eye is indirectly proportional to the lens power; thus, a greater distance is required for lenses with lower powers [18]. Ensuring proper cleaning of these lenses is vital to pre­vent contamination and cross infections [19].
3. Photography and videography: This is done using cameras mounted on the slit lamp or with digital compact cameras [20]. The fol­lowing adjustments are made in the slit lamp to permit photo-videography:
(a) A beam splitter is required to divide the
light traversing back from the patient's eye so that half of it travels to the exam­iner’s viewing system and the other half is captured by the photography system. Alternatively, a reex mirror system can divert all the light to the system.
(b) A crosshair graticule is incorporated in
one of the eyepieces, which allows proper centration of the area of photographic interest.
(c) Alongside the slit beam, a diffuse light
source is also necessary during slit lamp examinations. This additional light source
14 Slit Lamp Biomicroscopy
179
should have an intensity approximately 2–3 times dimmer than the slit beam. This diffuse light provides a softer illumina­tion that complements the focused slit beam, aiding in the observation of subtle details and enhancing the overall visibil­ity of ocular structures.
(d) The camera should be mounted in a man-
ner that it does not interfere with the optics, the observer's movement, or the illumination arm.
(e) The slit lamp is also equipped with an
electronic ash feature, specically designed with minimal exposure unaf­fected by eye movement. This feature ensures that the ash duration is extremely short, minimizing the risk of motion arti­facts and allowing for precise and accu­rate imaging of the ocular structures.
(f) With the advent of smartphones, it may
now be possible to do away with these elaborate systems, which are difcult to maintain and are expensive. Various adapters designed for smartphones enable obtaining high-resolution photographs conveniently during slit lamp examina­tions [21, 22].
4. Lasers: The integration of lasers into slit lamps expands the scope of these instruments from diagnostics to therapeutics. Discussing the indications, techniques, and uses of slit lamp lasers is beyond the scope of this chap­ter. Briey, these can be used for treating sev­eral conditions, including posterior capsule opacication through capsulotomy, angle clo­sure disease through iridotomy, macular edema, and neovascularization through retinal laser procedures, among others [2326].
more convenient for clinicians to transport and maneuver the slit lamp within clinical settings [27, 28]. It is also advantageous in operating rooms to examine patients under anesthesia and people in the supine position or immobile for various reasons. A handheld slit lamp proves particularly valuable when evaluating children who may not cooperate with a standard slit lamp examination. Additionally, its portability facilitates eye examinations in mass eye screenings, such as in school screenings [27].
(ii) Incorporation of software within the pho-
tography systems has resulted in “functional slit lamp examination.” This technique offers an in vivo method of assessing the hemodynamics of the conjunctiva by pro­viding the blood ow rate, velocity, vessel size, etc. [29] These parameters currently provide an insight into contact lens tting and dry eye disease, and this may soon expand to include other diseases as well.
(iii) Slit lamps have also been adapted to optical
coherence tomography (OCT) machines to enable instant OCT imaging of different ocular structures [30]. Quantitative assess­ment of the meibomian glands can also be performed with slit lamp adaptors [31].
Similar integration of additional diagnostic modalities, such as automated refractometry, pachymetry, tomography, or optical biometry into the slit lamp platform, holds the promise of comprehensive evaluations within a compact setup. The ability to conduct these investigations with a single instrument permits a more seamless workow and facilitates rapid decision-making in clinical practice.
14.8 Recent Advances andFuture Directions
There are several new developments in slit lamps. Some of these are as follows:
(i) Compact and portable: By reducing the size
and weight of the instrument, it becomes
14.9 Conclusion
The usefulness of the slit lamp for obtaining high­resolution images and adjustable illumination and magnication has revolutionized the evaluation of the anterior structures of the eye. It allows for identifying subtle abnormalities, precisely mea­suring structures, and monitoring changes over
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time. Incorporating handheld lenses further enhance these capabilities, enabling detailed viewing of angle structures and the posterior seg­ment. This aids in identifying pathologies, con­tributing to better treatment decisions and improved patient outcomes. With newer innova­tions, the instrument is becoming more compact, allowing a comprehensive range of functionality. Eventually, performing all basic diagnostic inves­tigations with one multipurpose instrument may become possible. By expanding its utility to encompass areas beyond diagnostics, the slit lamp continues to be a cornerstone instrument in oph­thalmology, empowering practitioners to provide comprehensive care and deliver improved ocular health outcomes for their patients.
Acknowledgments The authors are grateful to Drs. Simmy Chaudhary, Anasua Kapoor, Shilpa Tarani, and Rashmi Deshmukh for sharing their clinical photographs for publication.
Funding Hyderabad Eye Research Foundation, Hyderabad, India.
Disclosure None.
References
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2. Mazurak M, Kusa J.Jan Evangelista Purkinje: a pas­sion for discovery. Tex Heart Inst J. 2018;45(1):23–6.
3. Gellrich M.The slit lamp. 3rd ed. Berlin: Springer;
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4. Muirhead JF.Adolph Barkan (1845-1935), European ophthalmologist in San Francisco. JAMA Ophthalmol. 2014;132(3):346–9.
5. Ehinger B, Grzybowski A. Allvar Gullstrand (1862–1930)—the gentleman with the lamp. Acta Ophthalmol. 2011;89(8):701–8.
6. Gloor BRP. Hans Goldmann (1899-1991). Eur J Ophthalmol. 2010;20(1):1–11.
7. Littmann H. A new slit lamp apparatus. Am J Ophthalmol. 1950;33(12):1863–70.
8. Vogt A.Atlas of the slitlamp-microscopy of the living eye. Surv Ophthalmol. 1962;7:316–21.
9. Sanderson J. Fundamentals of microscopy. Curr Protoc Mouse Biol. 2020;10(2):e76.
10. Srinivas SP, Rao SK. Ocular surface staining: cur­rent concepts and techniques. Indian J Ophthalmol. 2023;71(4):1080–9.
11. Kaur K, Gurnani B. Slit-lamp biomicroscope. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [cited 2023 Jul 1]. http://www.ncbi.
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12. Martin R.Cornea and anterior eye assessment with slit lamp biomicroscopy, specular microscopy, confo­cal microscopy, and ultrasound biomicroscopy. Indian J Ophthalmol. 2018;66(2):195–201.
13. Fritz B, Paschko E, Young W, et al. Comprehensive compositional analysis of the slit lamp bacteriota. Front Cell Infect Microbiol. 2021;11:745653.
14. Oshika T, Mori M, Araie M. A new approach to the study of aqueous humor dynamics by measur­ing the intensity of Tyndall’s effect. J Fr Ophtalmol. 1990;13(10):471–80.
15. Baskaran M, Oen FTS, Chan YH, etal. Comparison of the scanning peripheral anterior chamber depth analyzer and the modied van Herick grading system in the assessment of angle closure. Ophthalmology. 2007;114(3):501–6.
16. Zeppieri M, Gurnani B.Applanation tonometry. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [cited 2023 Jun 30]. http://www.
ncbi.nlm.nih.gov/books/NBK582132/.
17. Brusini P, Salvetat ML, Zeppieri M.How to measure intraocular pressure: an updated review of various tonometers. J Clin Med. 2021;10(17):3860.
18. Gellrich MM. The fundus slit lamp. Springerplus. 2015;4:56.
19. Sobolewska B, Buhl M, Liese J, Ziemssen F. Slit lamps and lenses: a potential source of nosocomial infections? Eye (Lond). 2018;32(6):1021–7.
20. Honavar S, Sen M.Beauty and the beam: Slit-lamp photography essentials [Internet] [cited 2023 Jun 30].
https://ijoreports.in/article.asp?issn=2772- 3070;year =2022;volume=2;issue=3;spage=643;epage=646;aul ast=Honavar
21. Ludwig CA, Murthy SI, Pappuru RR, etal. A novel smartphone ophthalmic imaging adapter: user feasibility studies in Hyderabad, India. Indian J Ophthalmol. 2016;64(3):191–200.
22. Muth DR, Blaser F, Foa N, etal. Smartphone slit lamp imaging-usability and quality assessment. Diagnostics (Basel). 2023;13(3):423.
23. Modena DAO, Miranda ACG, Grecco C, et al. Efcacy and safety of ND:YAG 1064 nm lasers for photoepilation: a systematic review. Lasers Med Sci. 2020;35(4):797–806.
24. He M, Jiang Y, Huang S, et al. Laser peripheral iridotomy for the prevention of angle closure: a single- Centre, randomised controlled trial. Lancet. 2019;393(10181):1609–18.
25. Saha BC, Kumari R, Sinha BP, et al. Lasers in glaucoma: an overview. Int Ophthalmol. 2021;41(3):1111–28.
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26. Yadav NK, Jayadev C, Rajendran A, Nagpal M.Recent developments in retinal lasers and delivery systems. Indian J Ophthalmol. 2014;62(1):50–4.
27. Hu S, Wu H, Luan X, et al. Portable handheld slit- lamp based on a smartphone camera for cataract screening. J Ophthalmol. 2020;2020:
1037689.
28. Yazu H, Shimizu E, Sato S, et al. Clinical observa­tion of allergic conjunctival diseases with portable and recordable slit-lamp device. Diagnostics (Basel). 2021;11(3):535.
29. Shu X, Wang J, Hu L. A review of functional slit lamp biomicroscopy. Eye Vis (Lond). 2019; 6:15.
30. Mueller M, Schulz-Wackerbarth C, Steven P, et al. Slit-lamp-adapted fourier-domain OCT for ante­rior and posterior segments: preliminary results and comparison to time-domain OCT. Curr Eye Res. 2010;35(8):722–32.
31. Arita R, Itoh K, Maeda S, etal. A newly developed noninvasive and mobile pen-shaped meibography sys­tem. Cornea. 2013;32(3):242–7.
Corneal Topography
15
RashmiDeshmukh andSayanBasu
15.1 Introduction
The cornea is the anterior transparent optical ele­ment of the eye. It plays a vital role in focusing the rays of light on the retina. It contributes to two-thirds of the total refractive power of the eye. In Greek, “topos” means “place” and “graphien” means “to write.” Topography relates to studying a surface. Corneal topography was developed as a technique to analyze the anterior surface of the cornea. Traditionally, topography refers to a two­dimensional representation of the corneal sur­face. In contrast, “tomos” means “section”; corneal tomography is a three-dimensional repre­sentation of the cornea derived from the anterior and the posterior surfaces of the cornea [1]. A good understanding of the principles of corneal topography and tomography and the ability to interpret these images accurately is crucial to diagnose corneal disorders such as keratoconus, pellucid marginal degeneration, keratoglobus,
R. Deshmukh (*) · S. Basu Shantilal Shanghvi Cornea Institute, Kallam Anji Reddy Campus, L V Prasad Eye Institute, Hyderabad, India e-mail: sayanbasu@lvpei.org
regular or irregular astigmatism, or corneal ecta­sia following refractive surgery. With the recent increase in the number of people opting for refractive surgery, corneal topography has become an indispensable tool for screening them for their eligibility and determining the proce­dure of choice.
15.2 History
The rst measurements of the corneal shape were reported by Scheiner in 1619. He used convex mirrors of different curvatures next to the eye to see the reections of window panes until he found a mirror reecting an image of the same size as the cornea [2]. Cuignet developed the rst keratoscope to see the reected image from the cornea, and the rst keratometer was developed by Helmholtz in 1854. Using a keratometer made it possible to measure the curvature of the central 3 mm of the cornea by assessing the distance between two pairs of reected points. In 1882, Placido developed a disc with alternating black and white concentric rings with a convex lens at the center of the disc to view the reected image. This disc named after him (Placido disc) is still widely used by reection-based topographers. Using the Placido disc in keratometers made it possible to analyze data from a large surface area of the cornea. The following century did not see much progress until the developments of contact
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024 T. Das, P. Satgunam (eds.), Ophthalmic Diagnostics, https://doi.org/10.1007/978-981-97-0138-4_15
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184
lens tting techniques made it necessary to get information about the mid-peripheral curvature of the cornea. Further developments in cataract surgeries, keratoplasties, and corneal refractive surgeries necessitated the measurements of the curvature of a large area of the cornea. Developments in videokeratoscopy made these measurements possible. Further development of the Scheimpug principle used the principle of projection rather than reection to generate true elevation data.
15.3 Principles andTechnology
15.3.1 Reection-Based Systems
Many topography systems use the principle of reection-based imaging. The principle is to direct the reected light from the corneal sur­face onto a two-dimensional image capture sys­tem. A reection-based topographer typically has a Placido disc; it is illuminated and pro­jected onto the cornea. The reected image from the cornea is captured and analyzed to deter­mine the shape of the cornea. Keratoscopes and videokeratoscopes are examples of topogra­phers based on this principle. The NIDEK-OPD (Nidek Technologies, Gamagori, Japan) scan combines a Placido disc with ray tracing aber­rometry and measures anterior corneal curva­ture, refraction, and pupil size [3]. Most Placido-based topographers use 22 rings with an angular resolution of 2° and can be divided into small and large cone topographers. Small cone systems image more data points and are hence more accurate, but it might be challenging to image deep-set eyes with these systems [4].
There are some limitations to this technology. The posterior cornea cannot be measured. Anterior corneal measurements with the help of reected mires might miss minor abnormalities. A healthy ocular surface is a prerequisite for a good image; hence, using this technology on peo­ple with ocular surface disorders is difcult. Another major limitation is limited corneal cov­erage, as it obviates measurements from the para­central and peripheral cornea (Fig.15.1).
R. Deshmukh and S. Basu
Fig. 15.1 Corneal topography using Placido disc tech­nology shows poor peripheral cornea coverage
15.3.2 Slit Scanning System
Slit scanning topography combines the reection of a Placido disc with the projection of a slit beam, similar to a slit lamp biomicroscope [5]. The slit beam is moved across the cornea, getting refracted at the anterior and posterior corneal sur­faces. Ray tracing triangulation allows the math­ematical analysis of the reected and refracted rays of light to analyze the anterior and posterior surfaces of the cornea. Simultaneous measure­ments of the anterior and posterior corneal sur­face enable global pachymetry measurement. Orbscan I (Orbscan, Inc., Salt Lake City, UT, USA) was the rst attempt at imaging the poste­rior corneal surface using a slit scanning system. A Placido disc was incorporated in the Orbscan II (Bausch & Lomb, Rochester, NY), and the latest version, Orbscan IIz (Bausch & Lomb, Rochester, NY), has an integrated Hartmann-Shack aber­rometer [6].
15.3.3 Scheimpug Imaging
The Scheimpug principle describes the optical imaging condition when the plane of an object is not parallel to the lm of the camera; it has the
15 Corneal Topography
185
advantage of achieving a wide depth of focus. It was described by Theodor Scheimpug, an Austrian navy ofcer who noticed this phenome­non could correct the perspective distortion of aerially acquired photographs. The Pentacam (Oculus, Inc., Lynnwood, WA), Galilei (Ziemer, Port, Switzerland), and Sirius (CSO, Italy) imag­ing devices use this principle for corneal tomogra­phy [7]. The devices use sub-pixel edge detectors to precisely detect corneal and anterior chamber edges. This technology allows the measurements of anterior and posterior cornea, anterior chamber angle and depth, and corneal and lenticular densi­tometry measurements (Fig.15.2) [8].
The Pentacam is the most popularly used Schiempug system. It has a static camera in the center to image the pupil center and control xa­tion. A second rotating camera with a slit light
Fig. 15.2 A Scheimpug image showing the cornea, anterior chamber, and lens imaging
source obtains slit images from 0° to 180°. The analysis is then converted into detailed topogra­phy and thickness maps.
15.4 Color Coding Systems
The analyzed measurements represent keratome­try, pachymetry, and elevation maps. These maps show individual data points and are represented using the Louisiana State University Color Coded maps. In this scale, the warmer colors (orange and red) represent steeper corneas, thinner areas, and areas with a higher elevation than the refer­ence surface. The cooler colors (violet and blue) represent atter curvatures, thicker corneas, and areas that are depressed compared to the refer­ence surface. The greens and the yellows are seen in normal corneas.
The color scale can further be absolute or nor­malized. An absolute scale has a xed color cod­ing system with the same colors representing the same dioptric steps for a particular instrument. However, subtle changes are easily missed since the dioptric steps are large. In contrast, in a nor­malized scale, the system identies the minimum and maximum values for each map and automati­cally distributes the colors in a gradient manner. Since the increment step assigned to each color is smaller, this scale gives more topographic details (Fig.15.3).
Fig. 15.3 Absolute (right) and normalized (left) scale of the same keratometry map
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15.5 Concept ofBest-Fit Sphere
The concept of the best-t sphere is a fundamen­tal principle in corneal topography aimed at understanding the baseline curvature of the cor­nea. The corneal surface is prolate, and its shape is complex, varying across different regions. The best-t sphere represents a smooth, symmetrical sphere that minimizes the deviations or differ­ences between the two when superimposed onto the irregular corneal surface. It is a reference point to analyze and quantify corneal curvature changes accurately [9].
Elevation-based topography uses the best-t sphere as a reference surface and plots the points above or below the reference surface [10]. The areas below the reference surface are represented in cool colors, and the areas above the reference surface are represented in warm colors.
15.6 Topography Maps
15.6.1 Keratometry Maps
Keratometry is the measurement of the corneal radius of curvature. It is dened as the curvature of the circle that touches the cornea at a given point of interest. Keratometry maps essentially provide details of the curvature of the cornea at a given point. Consequently, these maps help assess whether the cornea is regular or irregular (as in corneal scars), steep or at and whether there are any corneal ectatic disorders. Depending on the method used for calculating the radius of curvature, keratometry or curvature maps are dis­played as either sagittal (axial) curvature maps or tangential curvature maps. Normal keratometry values range from 41D to 46D with a mean of 43D [11].
15.6.1.1 Axial Curvature Maps
In this type of map, the radius of curvature at a given point on the corneal surface is measured from a reference axis (optical axis). Due to this common reference axis, small irregularities may not be visible or “smoothened out” as they are much smaller than the large corneal diameter.
These maps are calculated assuming that all the rays of light striking the corneal surface are refracted, forcing a focal point through the opti­cal axis as a reference axis and assuming that the center of rotation of the best-t sphere center lies on the optical axis. It gives a good global view of the cornea averaging out the values and reducing noise. Axial curvature maps are particularly use­ful in classifying the corneal shape and determin­ing the base curve of the contact lenses for tting. However, details of minor irregularities may be missed [12].
15.6.1.2 Tangential Maps
These maps more closely represent the actual curvature of the cornea over the axial map. The tangential radius of curvature is calculated at each point with respect to its neighboring points by tting the best-t sphere. It means that the tan­gents are projected at each point, and curvature is measured along the tangent. This type of map recognizes sharp power transitions more easily than the axial map and is more sensitive to irregu­larities on the corneal surface. It is useful for evaluating corneal shape, assessing refractive surgery candidates, surgically induced changes, and tting contact lenses [13].
15.6.2 Pachymetry Maps
These maps show the distribution of corneal thickness at various points on the cornea. Normal central corneal thickness ranges from 500 to 550 μm and gradually increases toward the limbus. Most often, the thinnest point on the cornea would be close to or almost coincide with the corneal apex. Pachymetry maps are of particular importance while screening for refrac­tive surgery. A normal corneal thickness is a pre­requisite for performing laser vision correction. Displacement of the thinnest location from the apex indicates ectasia, especially when accompa­nied by posterior elevation and keratometric steepening at the corresponding points. A glob­ally thin cornea is seen in the keratoglobus, while a thick cornea might indicate endothelial dysfunction.
15 Corneal Topography
187
15.6.3 Elevation Maps
The anterior and posterior elevation maps display the areas in the anterior and posterior corneal sur­face above and below the reference surface. The most used reference surface is the best-t sphere. However, best-t ellipse and best-t toric ellip­soid can also be used. During screening for refractive surgery, a best-t sphere to the central 8mm zone provides adequate data points to rec­ognize subtle ectasias and astigmatism [14].
15.7 Interpretation ofMaps
A typical quad map consists of 4 maps: the kera­tometry map (usually axial keratometry), pachymetry map, anterior elevation map, and posterior elevation map. However, since the dis­plays might differ between each machine, one must read a map and look for the red ag signs pointing toward ectasias.
15.7.1 Orbscan
A normal Orbscan quad map includes a keratom­etry map, pachymetry map, and anterior and pos­terior elevation maps with measurements displayed at the center (Fig.15.4).
The Rousch and Efkarpides criteria give the
typical red ag signs on an Orbscan map.
15.7.1.1 Rousch Criteria [15]
(a) A thinnest pachymetry of <470μm. (b) A difference of >100 μm from the thinnest
point to the values of the 7mm optic zone implies a steep gradient of thinning from mid-periphery to the thinnest point.
(c) The thinnest point on the cornea should cor-
respond with the highest point of elevation of the posterior corneal surface. A posterior high point should be >50μm above the best­t sphere on posterior elevation maps. A best-t sphere of power >55D on the poste­rior prole is required.
Fig. 15.4 An Orbscan quad map with anterior elevation map (top left), posterior elevation map (top right), keratometry map (bottom left), and pachymetry map (bottom right). The central box displays measurements of various parameters
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(d) A relative difference of >100 μm between
the highest and lowest point on the posterior elevation map must be seen.
(e) Keratometric mean power map readings of
>46D and a lazy C on the axial power map are suspect when the astigmatism shifts >20° from a straight line.
(f) A change within the central 3mm optic zone
of the cornea of more than 3D from superior to inferior can be correlated to the presence of vertical coma (the commonest aberration in keratoconus).
(g) Composite integrated information, which
includes the highest point on the posterior elevation, coincides with the highest point on the anterior elevation, the thinnest point on pachymetry, and the point of steepest curva­ture on the power map, can be acquired.
Additionally, the Efkarpides criteria suggest that ratio of the radii of the anterior and posterior
best-t spheres of the cornea should be >1.21. An astigmatic discrepancy of >1.5D in the 3 mm zone and a discrepancy of >2D in the 5mm zone should be an alert sign.
15.7.2 Pentacam
A standard Pentacam map (Fig. 15.5) displays certain numerical values on the left-hand side of the map.
Quality specication (QS): Species the quality of the topographic capture and should be displayed as “OK.” Otherwise, the Pentacam software tends to extrapolate the missing information leading to false readings in the missed areas.
K-readings: K1 indicates at keratometry, K2 indicates steep keratometry. Consider at K while treating myopia (should not be <34D
Fig. 15.5 Normal Pentacam display of a quad map with axial keratometry map (top left), pachymetry map (bot­tom left), anterior elevation map (top right), and posterior
elevation map (bottom right). The rectangular display on the left shows various parameters