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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_605_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Biomedical Engineering in Gastrointestinal Surgery
- •Copyright
- •Contents
- •Foreword
- •Acknowledgments
- •2.1.3 Attrition and Erosion
- •2.2 Esophagus
- •2.2.1 Anatomical Description
- •2.2.2 Functional Task
- •2.2.3 Disorders and Diseases
- •2.2.4 Cancer
- •2.2.5 Biomedical Engineering Aspects
- •2.2.5.1 Internal (Endoscopic) Reinforcement
- •Reference
- •2.1 The Gastrointestinal Tract: an Overview
- •2.1.1 Structural Defects
- •2.1.2 Functional Defects
- •2.2.5.2 Implants
- •2.2.5.3 Electrical Stimulation
- •2.3 Stomach
- •2.3.1 Anatomical Description
- •2.3.2 Functional Task
- •2.3.3 Disorders and Diseases
- •2.3.4 Biomedical Engineering Aspects
- •2.4 Duodenum and Small Intestine
- •2.4.1 Anatomical Description
- •2.4.2 Functional Task
- •2.4.3 Disorders and Diseases
- •2.4.4 Biomedical Engineering Aspects
- •2.5 Colon and Rectum
- •2.5.1 Anatomical Description
- •2.5.2 Functional Task
- •2.5.3 Disorders and Diseases
- •2.5.4 Biomedical Engineering Aspects
- •2.6 Liver/Gallbladder
- •2.6.1 Anatomical Description
- •2.6.2 Functional Task
- •2.6.3 Disorders and Diseases
- •2.6.4 Biomedical Engineering Aspects
- •2.7 Pancreas
- •2.7.1 Anatomical Description
- •2.7.2 Functional Task
- •2.7.3 Disorders and Diseases
- •2.7.4 Biomedical Engineering Aspects
- •References
- •3.1 Definition
- •3.2 Basic Surgical Principles
- •3.2.1 Wound Healing, Wound Treatment
- •3.2.2 Indications for Surgery
- •3.2.2.1 Emergency Surgery
- •3.2.2.2 Urgent Surgery
- •3.2.2.3 Semielective Surgery
- •3.2.2.4 Elective Surgery
- •3.2.3 Steps of the Operation
- •3.2.3.1 Positioning on the OR Table
- •3.2.3.2 Incision
- •3.2.3.3 Exposure
- •3.2.3.4 Dissection
- •3.2.3.5 Resection
- •3.2.3.6 Specimen Retrieval
- •3.2.3.7 Viscerosynthesis/Reconstruction
- •3.2.3.8 Wound Closure
- •3.3 Structure and Organization of Surgical Care
- •3.3.1 Outpatient Surgical Care
- •3.3.2 In-Hospital Surgical Care
- •3.3.2.1 Emergencies in Visceral Surgery
- •3.3.2.2 Elective Surgery
- •3.3.2.3 Hospital Beds
- •4.1 Asepsis
- •4.1.1 The Detection of Antisepsis
- •4.1.2 Reprocessing of Surgical Instruments
- •4.1.3 Sterilization
- •4.2 Anesthesia
- •4.2.1 Sedation
- •4.3 Dedicated Workplace: The Operating Room
- •4.3.1 The Surgical Workplace
- •4.3.2 Core Elements of the Surgical Site
- •4.3.3 Stationary Systems
- •4.3.4 Typical Surgical Positions in Visceral Surgery
- •4.3.5 Maximum Load
- •4.3.6 Cleaning and Disinfection
- •4.3.7 Operating Lights
- •4.3.8 Peripheral Devices
- •4.3.9 Structural Preconditions
- •References
- •5.1 Conventional Radiology
- •5.1.1 Technical Aspects
- •5.1.2 Generation and Detection of X-Rays
- •5.1.3 Projection Radiography
- •5.1.4 Real-Time Radiography
- •5.2 Computed Tomography
- •5.2.1 Principle of Computed Tomography
- •5.2.2 Multislice Computed Tomography
- •5.2.3 Cone Beam Computed Tomography
- •5.2.4 Dual-Energy Computed Tomography
- •5.3 Magnetic Resonance Imaging
- •5.3.1 General Considerations
- •5.3.2 Technical Insights
- •5.3.3 Contrast Agents for Magnetic Resonance Imaging
- •5.3.4 Magnets
- •5.3.5 Real-Time Magnetic Resonance Imaging
- •5.3.6 Magnetic Particle Imaging
- •5.2.5 Dual-Source Computed Tomography
- •5.2.6 Phase-Contrast Computed Tomography
- •5.2.7 X-Ray Microtomography
- •5.2.8 Electron-Beam Computed Tomography
- •5.4 Diagnostic Ultrasound
- •5.4.1 History
- •5.4.2 Transducer Arrays
- •5.4.3 US Application in Visceral Medicine
- •5.4.4 Doppler Imaging
- •5.4.5 US Elastography
- •5.4.5.1 Acoustic Radiation Force Impulse Imaging
- •5.4.5.2 Shear Wave Elastography
- •5.4.5.3 Shear Wave Dispersion Ultrasound Vibrometry
- •5.4.6 3D/4D Ultrasound
- •5.4.7 Ultrasound Computed Tomography
- •5.5 Nuclear Imaging Systems
- •5.5.1 Gamma Camera
- •5.5.2 Positron Emission Tomography
- •5.5.3 Single-Photon Emission Computed Tomography
- •5.5.4 Conclusion
- •5.6 Advanced Optical Systems
- •5.6.1 Photodetectors
- •5.6.2 Optical Coherence Tomography
- •5.6.2.1 Time-Domain Optical Coherence Tomography
- •5.6.2.2 Fourier-Domain Optical Coherence Tomography
- •5.6.2.3 Fourier-Domain Doppler Optical Coherence Tomography
- •5.6.3 Optical Fluorescence Imaging
- •5.6.4 Hyperspectral Imaging
- •5.6.5 Diffuse Optical Imaging (Near-Infrared Optical Tomography)
- •5.6.6 Confocal Laser Scanning
- •5.6.7 Photoacoustic Imaging
- •5.6.8 Conclusion
- •5.7 Endoscopy
- •5.7.1 Rigid Endoscopes
- •5.7.2 Flexible Diagnostic Endoscopy
- •5.7.2.1 Flexible Scopes
- •5.7.2.1.1 The Handle
- •5.7.2.1.2 Connection to the Control/Supply Unit
- •5.7.2.2 Control/Support Unit
- •5.7.2.2.1 Imaging/Illumination
- •5.7.2.2.2 Suction/Irrigation/Insufflation
- •5.7.2.3 Instruments
- •5.7.2.4 The Endoscopic Trolley
- •5.7.2.5 Instrument Reprocessing
- •5.7.2.6 Clinical Applications
- •5.7.2.6.1 Colonoscopy
- •5.7.2.6.2 Enteroscopy, “Deep Endoscopy”
- •5.7.3 Autofluorescence Imaging Endoscopy
- •5.7.4 Computed Virtual Chromoendoscopy/Narrow Band Imaging (NBI)
- •5.7.5 Confocal Endomicroscopy
- •5.7.6 Endoscopic Optical Coherence Tomography
- •5.7.7 Endoscopic Ultrasound
- •5.7.8 Wireless Capsule Endoscopy
- •5.7.9 Conclusion
- •5.8 Hybrid Systems
- •5.8.1 Real-Time Virtual Sonography
- •5.8.2 Positron Emission Tomography/Computed Tomography
- •5.8.3 Single-Photon Emission Computed Tomography/Computed Tomography
- •5.8.4 Positron Emission Tomography/Magnetic Resonance Imaging
- •5.8.5 Single-Photon Emission Computed Tomography/Magnetic Resonance Imaging
- •5.8.6 X-Ray/MRI
- •5.8.7 Integrated Optical Coherence Tomography Ultrasound Imaging System
- •5.8.8 Integrated Optical Coherence Tomography and Positron Detection
- •5.8.9 Microscope Integrated Optical Coherence Tomography and Optical Coherence Microscope
- •5.9 Intraoperative Diagnostic Procedures
- •5.9.1 Ultrasound
- •5.9.2 Conventional Radiography (C-Arm)
- •5.9.3 Isocentric Radiography
- •5.9.4 Intraoperative Volume Data Acquisition
- •5.9.5 Intraoperative Computed Tomography/Magnetic Resonance Imaging
- •References
- •6.1 “Classical” Surgical Instruments for Conventional Surgery
- •6.1.1 Surgical Knives/Scalpels
- •6.1.2 Forceps/Tweezers
- •6.1.2.1 Basic Forceps Designs
- •6.1.3 Scissors
- •6.1.4 Fixation Instruments/Locking Forceps
- •6.1.4.1 Hemostats
- •6.1.4.2 Vascular Clamps
- •6.1.5 Retractors
- •6.1.6 Self-Retaining Retractors
- •6.1.7 Needle Holders
- •6.1.8 Others
- •6.2 Electrosurgery
- •6.2.1 Thermal Low-Temperature Effects
- •6.2.2 Hyperthermia and Devitalization
- •6.2.3 Thermal Coagulation
- •6.2.4 Thermal Desiccation
- •6.2.5 Thermal High-Temperature Effects
- •6.2.6 Carbonization
- •6.2.7 Vaporization
- •6.2.8 Principles of Electrosurgery
- •6.2.9 Physical Theories of Electrosurgery
- •6.2.10 Electrosurgical Techniques
- •6.2.11 Monopolar Technique
- •6.2.12 Electrosurgical Coagulation and Desiccation (Hemostasis)
- •6.2.12.1 Impedance-Controlled Electrocoagulation
- •6.2.12.2 Argon Plasma Coagulation
- •6.2.13 Electrosurgical Cutting
- •6.2.14 Electrosurgical Unit
- •6.2.15 Clinical Aspects of Electrosurgery
- •6.3 Ultrasound Dissection
- •6.4 Water Jet
- •6.5 Stapling Devices
- •6.5.1 Linear staplers
- •6.5.2 Linear Cutting Devices
- •6.5.3 Circular Staplers
- •6.6 Biomaterials
- •6.6.1 Surgical Suture Materials
- •6.6.1.1 Absorbability
- •6.6.1.2 Internal Structure
- •6.6.2 Surgical Mesh
- •References
- •7.1 Basics
- •7.1.1 Pneumoperitoneum
- •7.1.1.1 Creation of the Necessary Space
- •7.1.2 The Veress Needle
- •7.1.2.1 Insertion of the Veress Needle
- •7.1.3 Gas Insufflators
- •7.1.3.1 Insufflation Device
- •7.1.3.2 Creation of the Pneumoperitoneum
- •7.1.4 Trocars
- •7.1.4.1 Reusable Trocars
- •7.1.4.2 Disposable Trocars
- •7.1.4.3 Hybrid Systems
- •7.1.5 Visualization
- •7.1.5.1 Laparoscopes (Laparoscopic Telescopes)
- •7.1.5.1.1 Advanced Laparoscopes
- •7.1.5.1.2 Future Developments
- •7.1.5.2 Laparoscopic Cameras
- •7.1.5.3 Laparoscopic Image Processors (Camera Control Unit)
- •7.1.5.4 Monitors
- •7.1.5.5 3D Endoscopy
- •7.1.6 Light Source and Transmission
- •7.1.6.1 Halogen Lamps
- •7.1.6.2 Xenon
- •7.1.6.3 Halide Lamps
- •7.1.6.4 Condensing Lens
- •7.1.6.5 Illumination Control
- •7.1.6.6 Light Cables
- •7.1.7 Suction/Irrigation Device
- •7.1.8 Documentation
- •7.1.9 Equipment Cart
- •7.2 Hand Instruments
- •7.2.1 Forceps/Graspers
- •7.2.2 Dissectors
- •7.2.3 Scissors
- •7.2.4 Needle Drivers
- •7.2.5 Retractors
- •7.2.6 Laparoscopic Electrosurgery
- •7.2.7 Clips and Clip Appliers
- •7.2.8 Laparoscopic Stapling Devices
- •7.2.9 Laparoscopic Ultrasound Dissection
- •7.2.10 Impedance-Guided Dissection
- •7.3 Minilaparoscopic Procedures
- •7.4 Mono-Port (Single Port) Surgery
- •7.4.1 Trocars
- •7.4.2 Hand Instruments
- •7.4.2.1 The SPIDER Surgical System
- •7.4.2.2 Critical Comments and Outlook
- •References
- •8.1 “Operative” Endoscopes
- •8.1.1 Upper Gastrointestinal Scopes, Colonoscopes
- •8.1.2 Side-Viewing Duodenoscopes
- •8.2 Instruments
- •8.2.1 Knives
- •8.2.2 Hooks
- •8.2.3 Snares
- •8.2.4 Injection Needles
- •8.2.5 Forceps/Graspers
- •8.3 Clips
- •8.3.1 Standard endoscopic clips
- •8.3.2 Over-the-Scope-Clip
- •8.4 Clinical Applications
- •8.4.1 Gastrointestinal Bleeding
- •8.4.1.1 Injection Therapy
- •8.4.1.2 Thermal Hemostasis
- •8.4.1.2.1 Contact Methods
- •8.4.1.2.2 Noncontact Methods
- •8.4.1.3 Mechanical Methods
- •8.4.2 Percutaneous Endoscopic Gastrostomy
- •8.4.3 Endoscopic Resection of Neoplastic Tissue
- •8.4.3.1 Snare Polypectomy
- •8.4.3.2 Endoscopic Mucosal Resection
- •8.4.3.3 Endoscopic Submucosal Dissection
- •8.4.4 Endoscopic Interventions on the Bile Duct (ERCP)
- •8.4.5 Gastrointestinal Stenting
- •8.4.5.1 Bougienage and Balloon Dilatation
- •8.4.6 Outlook
- •References
- •9.1 Combined Laparoscopic-Endoscopic Procedures (CLEP)
- •9.1.1 Indications
- •9.1.2 Esophagus
- •9.1.3 Stomach
- •9.1.4 Duodenum
- •9.1.5 Colon
- •9.1.6 Contraindications
- •9.1.7 Tumor Localization
- •9.1.8 Defining the Line of Section (Margin)
- •9.1.9 Selection of the Appropriate Technique for Tumor Resection
- •9.1.10 Specimen Retrieval
- •9.1.11 Leak Test
- •9.1.12 Technical Considerations
- •9.2 Natural Orifice Transluminal Endoscopic Surgery—Surgery Without Visible Scars
- •9.2.1 Access into the Abdominal Cavity
- •9.2.1.1 Transgastric Approach
- •9.2.1.2 Transurethral Approach
- •9.2.1.3 Transvaginal Approach
- •9.2.1.4 Transcolonic Approach
- •9.2.2 Intestinal Closure
- •9.2.2.1 Clips
- •9.2.2.2 Suturing Devices
- •9.2.3 Flexible Staplers
- •9.2.4 Plicator-Like Devices
- •9.2.5 Rivets
- •9.3 Spatial Orientation
- •9.4 Illumination
- •9.5 Fog/Mist Elimination
- •9.6 Stabilization of the Horizon
- •9.7 View Extension
- •9.8 Three-Dimensional Stereoscopy
- •9.9 Multifunctional Endoscopes and Mechanical Platforms
- •9.9.1 Endosamurai
- •9.9.2 Anubis
- •9.9.3 SPOT (Single Port Overtube System), Technische Universität München
- •9.10 Outlook
- •References
- •10.1 Computerized Systems
- •10.1.1 Active Camera Holders
- •10.1.1.1 Automated Endoscope System for Optimal Positioning
- •10.1.1.2 Currently Available Active Camera Holders
- •10.1.1.3 Conclusion and Further Development
- •10.1.2.1 Zeus
- •10.1.2.2 DaVinci
- •10.1.2.3 New Developments
- •10.1.2.3.1 Titan SPORT
- •10.1.2.3.2 Senhance Surgical Robot System
- •10.1.2.3.3 MiroSurge
- •10.1.3 Computerized Platforms for NOTES
- •10.1.3.1 Electromechanically Controlled Conventional Endoscopes
- •10.1.3.2 Systems With Elements of Autonomous Locomotion
- •10.1.3.2.1 Endotic
- •10.1.3.2.2 Aer-O-Scope
- •10.1.3.3 Robotically Driven Instrumentation
- •10.1.3.3.1 Single Access and Transluminal Robotic Assistant for Surgeons (ISIS-STRAS)
- •10.1.3.3.2 C-SPOT
- •10.1.3.3.3 MASTER (Master and Slave Transluminal Endoscopic Robot)
- •10.1.3.3.4 Endomina
- •10.2 Nontethered (Cable-Less) Systems/Modular Assembling Reconfigurable Miniature Robots
- •10.2.1 ARES
- •10.2.2 ARAKNES
- •10.3 Special Aspects of Roboterized Surgery
- •10.3.1 Haptic Feedback
- •References
- •11.1 Optical Tracking Systems
- •11.2 Electromagnetic Tracking Systems
- •11.3 Fiber Bragg Grating Sensors
- •11.4 Radio-Based Tracking Systems
- •11.4.1 Radio-Frequency Identification Devices
- •11.4.2 RFID Applications in Health Care
- •11.4.3 Bluetooth
- •11.4.4 Wi-Fi
- •11.4.5 ZigBee
- •11.4.6 Ultra-Wide Band
- •11.4.7 RuBee
- •11.5 Acoustic Tracking Systems
- •11.6 Inertial Tracking Systems
- •11.7 Others
- •11.7.1 Depth Maps, 3D Surface Reconstruction
- •11.7.2 Passive Methods
- •11.7.2.1 Stereoscopy
- •11.7.3 Monocular Shape-From-x
- •11.7.4 Simultaneous Localization and Mapping
- •11.7.5 Active Methods
- •11.7.5.1 Time-of-Flight (ToF)
- •11.7.5.2 Structured Light (Color-Coded Triangulation)
- •11.8 Strengths and Weaknesses of Real-Time 3D Surface Reconstruction Methods
- •References
- •12.1 Hospital Information Systems
- •12.1.1 Specialty-Specific Extensions
- •12.1.1.1 Picture Archiving and Communication System
- •12.1.1.2 Others
- •12.1.2 Health Informatics On-Site
- •12.1.2.1 HIS in the Outpatients (Preadmission) Department
- •12.1.2.2 HIS in the Surgical Floor
- •12.1.2.3 HIS for Multidisciplinary Conferences
- •12.1.2.4 HIS in the OR
- •12.1.2.5 HIS and Quality of Care
- •12.1.2.6 Data Mining
- •12.2 Surgical Telematics/”Telesurgery”
- •12.2.1 Teleconsultation
- •12.2.2 Telepresence
- •12.2.3 Telesurgery
- •References
- •13.2 Cadaver Studies
- •13.3 Live Animal Training

Classical (Open) Surgery
Figure 6.16 (A) A selection of dedicated vascular clamps: (a) Bulldogs forceps: This
is a class of forceps differing considerably from normally hinged forceps. It is spring
loaded. By squeezing the proximal shanks, the tip opens and the forceps is positioned on the artery. By releasing the pressure, the vessel is occluded. (b) Satinsky
clamp; (c) Cooley clamp. Particularly suitable for tangential temporary exclusion
of larger vessels; (d) Dardik; (e) De Bakey: The long tips enable to modify the pressure
exerted to the tissue: The closer to the articulation the tissue is positioned, the
stronger is the force. (B) Straight and curved Bulldog clamps (magnified). All from MITI.
231
exerts significantly less trauma. After successful surgical repair, blood flow
is reestablished by releasing the clamps. Any pressure damage to the vascular
wall—in particular of the intima (innermost layer)—favors the formation of
thrombosis and endangers the success of the surgery.
The difficult combination of (elastic) strength and gentle manipulation
of the tissue stimulated the design of very sophisticated vascular clamps
(
Fig. 6.16).
Bulldog clamps are a particular subtype of hemostats with a very short
handle. They can be positioned in the surgical site when it is very
crowded. The jaws are opened by squeezing the handle. When the
pressure is released from the handles, the clamp closes and stops blood
flow until it is removed again.
Vascular clamps are not exclusively used by vascular or cardiac surgeons
but by visceral surgeons as well.
6.1.5 Retractors
Surgical retractors are medical instruments used to separate the edges
of a wound or incision. This instrument offers surgeons access to an area,
while inflicting a min imal amount of damage to the wound. Surgical
technologists or assistants may be responsible for holding these

232
Biomedical Engineering in Gastrointestinal Surgery
Figure 6.17 (A) Handheld retractors: (a) Gillies hook with sharp, thorn-shaped tips
for skin retraction; (b) Volkmann hook: Sharp teeth to retract skin/subcutaneous
tissue; (c) Langenbeck hook: Smooth blades; (d) Roux hooks; (e) Abdominal wall
retractor (Fritsche); (f) Retractor for internal organs (Doyen), such as liver and small
bowel. (B) Instrument tray with a variety of retractors. All from MITI.
Figure 6.18 (A) A pair of Roux hooks to separate the edges of an inguinal incision;
(B) Liver hook (1) maintains the adequate position of the liver to give access to the
hepatoduodenal ligament. All from MITI.
instruments in place during an operation. In addition to handheld retractors (
Fig. 6.17A), so-called self-retaining retractors are available. They are
usually provided together in the so-called retractor tray (
Fig. 6.17B).
For an optimal exposure of the surgical site, it is of utmost importance
to hold back the adjacent tissues and organs, which is often a tedious and
boring task for the assistant whose task it is (
Fig. 6.18).
6.1.6 Self-Retaining Retractors
Retractors have to distract incisions and accesses by exerting traction
forces on both sides of the access. Accordingly, two hooks are required.

Classical (Open) Surgery
233
Figure 6.19 Two types of self-retaining retractors: (A) Self-retaining retractor for skin
incision (Weilander). The jaws are kept within their selected position by the arresting
mechanism with the liver. (B) Four (or more) hooks are mounted on a ring to keep
an abdominal incision open (Zenker). From MITI.
If these are connected by a hinge, the distension force can be maintained
mechanically (
Fig. 6.19).
Self-retaining retractors often enable the surgeon to do the operation
(usually smaller ones) without the help of an assistant (“solo surgery”)
(
Fig. 6.20).
For larger incisions, in particular of the abdominal wall, more complex
devices are in use. In
Fig. 6.21 a ring-shaped retractor (Zenker) and an addi-
tional pulled hook are shown. The pulled hook is connected to an anchor.
The traction can be varied to permit a wide access to the abdominal cavity.
6.1.7 Needle Holders
The purpose of this hemostat-like instr ument is to hold the surgical
needle firmly during surgery. Whereas a tailor is able to manipulate the

234
Biomedical Engineering in Gastrointestinal Surgery
Figure 6.20 Self-retaining retractor in situ. The two edges of skin/subcutaneous tissues are kept apart, facilitating further tissue dissection in deeper layers. From MITI.
Figure 6.21 Abdominal incision. Hooks mounted to the metal ring permit a good
access to the abdominal organs. Note the additional pulled hook. From MITI.
needle with bare fingers, suturing in surgery is only feasible by the use of
needle holders. Usually, needle holders have an integrated clamp mechanism which locks the needle in place as long as it is required. Two main
types exist: The Mayo-Hegar (
(
Fig. 6.22B). In a Mayo-Hegar needle driver the clamp mechanism is
Fig. 6.22A) and the Mathieu variant
released by lateral pressure to the bows. The Mathieu-type needle holder
is opened by squeezing the handles beyond the point of arrestment.

Classical (Open) Surgery
Figure 6.22 The most often used needle drivers in abdominal surgery: (A) MayoHegar; (B) Mathieu. From MITI.
235
The design of the tip is a particular challenge. On the one hand,
a firm grip on the needle has to be maintained. On the other hand, any
mechanical deformation of the needle has to be avoided strictly. The
texture or structure of the jaws must offer the best trade-off. As soon
as they are becoming blunt, they have to be exchanged (
Fig. 6.23).
In surgical ORs all over the world, it is striven to provide the
instruments in a very standardized manner and adapted to the particular
application. Standardized containers for basic surgical operations (
Fig. 6.24)
are complemented by additional specialized containers.
6.1.8 Others
In addition to the “general purpose” instruments as mentioned above,
a wide range of highly specialized instruments is additionally provided.
They are designed to enable the surgeon to perform only one or just
a few well defined—but cr ucial—steps of the operation.
Stone forceps are a typical example. These funny shaped instruments
are required to remove stones out of the common bile duct or the pelvis
of the kidney/ureter (
Fig. 6.25).

Figure 6.23 Needle driver in action. It is locked, keeping the needle in a
stable position which overcomes tissue resistance. The needle is fixed in a rectangular position. From MITI.
Figure 6.24 Two instrument trays for basic surgical interventions. (A) Clockwise:
Hemostats, retractors, scissors, forceps. (B) Clockwise: Pads, kidney dishes, clip
applier. All from MITI.

Classical (Open) Surgery
Figure 6.25 Stone forceps. The different angles allow for a good anterograde and
retrograde positioning of the forceps within the duct system. From MITI.
237
Another instructive example of a highly specialized instrument is the
so-called purse string clamp. If it is considered necessary to perform a socalled “staple anastomosis” using a circular stapler, the stump of the GI
tract which will later on bear the anvil of the stapler (usually distal esophagus or proximal colonic stump) has to be prepared by means of a purse
string (see
Section 6.5: Stapling Devices). A purse string is a continuous
suture which is stitched around the circular edge of the stump.
When it is closed by knotting, the shaft of the anvil will fit snugly
into the stump. This time-consuming process of stitching the suture
around the edge can be considerably simplified by applying the suture
clamp (
Fig. 6.26).
For the nonsurgical reader, the detailed mode of action is perhaps difficult to understand, but the message should be clear: Even in conventional surgery, particular problems which were valid in surgery for many
decades can be overcome by the invention of an apparently simple and
logical new approach (“the egg of Columbus”). The authors are convinced that there is—still after about 150 years of conventional surgery—
a high potential for improvements, like the one shown above.
6.2 ELECTROSURGERY
When using the principles of electrosurgery to cut tissue, heat is applied
only to small locally distinct tissue areas. Electrosurgery does not have
an impact on the systemic temperature of the patient, but it does have

Figure 6.26 The purse string clamp: (A) The highly sophisticated jaws have specially
designed teeth with needle canals. After correct positioning of the clamp, the surgeon
just has to place the two needles of a double armed suture through the two needle
channels and to remove the clamp. (B) Sigmoid resection: The upper part has to be
removed. The lower part remains in the body. Later, it has to receive the anvil of the
circular stapler (see
der. (C) The two needles of a thread are inserted into the needle channels. (D) The upper
part of the sigmoid is cut off with a scalpel. (E) The clamp is removed. Note the two
ends of the purse string suture (above). The anvil can now be introduced. All from MITI.
Section 6.5: Stapling Devices). The clamp is positioned on the bor-

239Classical (Open) Surgery
a severe impact on local tissue and therefore cells adjacent to the heat
input. Thermal effects occur if cells are exposed to temperatures out of
the thermo-neutral zone between 35˚C and 41.5˚C. All thermal effects
are dependent on the intensity and duration of the thermal input. It is,
therefore, not important how the specific temperature is reached and how
it is induced. This chapter will further breakdown low- and hightemperature effects into five groups of thermal effects that biological tissue
can pass through when it is heated above 37˚C.
6.2.1 Thermal Low-Temperature Effects
Human beings are homeothermic. That means that the core temperature
is regulated by internal metabolic processes within a narrow bandwidth
of 0.5 K. The human body core temperature is 37˚C independently
of the ambient conditions. This core temperature is needed to maintain
all physiological processes running and is regulated by the hypothalamus
by dilation and contraction of blood vessels. Human cells are very sensitive to temperature changes. The first effects occur at around 35˚C if the
temperature is lowered and 41.5˚C if the temperature is increased. Both
effects are used for medical purposes.
Targeted lowering of local temperature is used, e.g., for cryotherapy
to destroy lesions. Heating of tissue has an influence which is used for different purposes. Since electrosurgery is mainly based on heat, only tissue
effects due to increasing temperature are described in detail.
gives an overview of the low-temperature effects of hyperthermia, devitalization, coagulation, and desiccation, furthermore showing the different
thermal effect zones exemplified for a monopolar active electrode
The thermal effect which is induced by the highest thermal input always
lies in the closest proximity to the active electrode.
Fig. 6.27A
[5].
6.2.2 Hyperthermia and Devitalization
When normal body temperature is raised no irreversible effects will occur
until the tissue temperature reaches 41.5˚C. This temperature zone is
called “hyperthermia.” If the temperature of human tissue is raised above
41.5˚C an irreversible “devitalization” effect will occur. At this temperature level time is of great importance. With increasing temperature the
devitalization will stride forward and will irreversibly damage the tissue.
The devitalization effect is time-dependent up to a temperature of 49˚C.
If temperatures of more than 49˚C are reached the devitalization of the

240
Biomedical Engineering in Gastrointestinal Surgery
Figure 6.27 Thermal low- and high-temperature effects—high-frequency current
application to tissue through a monopolar electrode causes diverse thermal defects.
(A) Low-temperature effects are caused through ohmic current flow from the electrode to the tissue and can be divided into three zones: temperatures above 41.5°C
lead to devitalization; temperatures above 60°C lead to coagulation; and temperatures up to 100°C lead to desiccation. (B) High-temperature effects are caused by
electrical arcs sparking from the electrode to the tissue and can be divided into two
zones: temperatures above 200°C leading to carbonization and temperatures above
500°C leading to vaporization of tissue. To achieve high-temperature effects temperature ranges that cause low-temperature effects have to be passed through. Thermal
effects occurring at the highest temperatures are always in closest proximity of the
electrode. From MITI.
target tissue will occur almost instantaneously. One of the two treacherous
characteristics of devitalization is the low-temperature difference to the
standard tissue temperature by only 4.5˚C. Furthermore, the fact that
devitalized tissue does not change in tissue color or structure and therefore cannot be seen with reasonable effort is cr ucial. If heat input has
raised the tissue temperatures above 41.5˚C and below 60˚C, the tissue
will be damaged irreversible, nevertheless not noticeable for the human eye
[6]. Surgeons and endoscopists do not have the ability to make the devitali-
zation zone visible. If the devitalization reaches into the muscularis propria
and the damaged muscle tissue disintegrates several hours after the intervention, delayed perforations and bleedings may occur. These are dangerous
to life and must be surgically treated instantly. During cutting and coagulation processes, the devitalization is an unintended side effect, but it can also
be used meaningful, e.g., for tumor destruction.
6.2.3 Thermal Coagulation
The second low-temperature effect is called “thermal coagulation” and sets
in at a temperature level above 60˚C. Coagulation is defined as the
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