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Procedure 34  | The Transpsoas Approach for Thoracolumbar Interbody Fusion    319
S T E P 3 P EA R L S
• When performing this procedure at rostral levels, the diaphragm can push the surgeon’s dilators and retractor downward. Therefore it is important to push the diaphragm out of the way when coming in with the PAK needle and various dilators.
• The authors secure the retractor to the vertebra with a pin. Depending on the angulation of the retractor and the location of the retractor on the vertebral body, the authors choose a vertebral body where the risk of injuring a segmental vessel is least likely, and, if this is the rostral toward the chest, they prefer to secure the retractor to the more rostral vertebra to maximize resistance against the rib cage.
Step 3
n
The C-arm is swung to the anteroposterior position.
n
Serial dilators are used to sequentially dilate the psoas muscle. Figure 34-4, A
is a fluoroscopic image showing first dilator being passed over the guidewire down to the level of the disk space. Figure 34-4, B shows serial dilators being placed in this matter to open a working channel between fibers of the psoas muscle. The dilators should be gently rotated back and forth during placement to separate the fibers of the psoas.
n
Free-run and triggered electromyography are only useful in identifying motor
nerve structures and do not aid in identifying any sensory branches.
n
Dilator placement may elicit a free-running electromyographic response, which
indicates mechanical irritation to the motor nerve structures. This is just an indication of mechanical contact.
n
Some manufacturers offer directional stimulated dilators, which use triggered
electromyography to identify the location of motor nerve structures. The dilator is rotated during insertion, while constant electrical current is applied or variable current stimulation is performed. The subsequent electromyographic response assists with motor nerve identification relative to the dilator. Directionally stimu­lated dilators of increasing size are inserted sequentially until the retractor is placed over the final dilator.
A
FIGURE 34-4, A-B 
B
320    Procedure 34| The Transpsoas Approach for Thoracolumbar Interbody Fusion
n
At this point, a small surgical field is within view at the deep end of the retractor.
Some surgeons prefer to perform the procedure through this port, while others choose to expand the retractor to allow a larger field of vision.
n
A shallow or short docking retractor technique has also been described for dis-
secting through the psoas to identify any neural structures before docking against the vertebral body.
n
Direct field stimulation using a ball-tip stimulating probe can be helpful for
identifying any motor nerve structures that may be pressed between the annulus and the retractor.
n
Any suspected neural structures can be swept out of the field.
n
The ball-tip probe stimulator should be used to sweep the area before pin or
shim placement for anchoring of the retractor system. The retractor is then secured to the patient with a pin in the vertebra.
n
The retractor is then further secured to the table using an articulating arm
(Figure 34-5).
A
FIGURE 34-5, A-B 
B
Procedure 34  | The Transpsoas Approach for Thoracolumbar Interbody Fusion    321
S T E P 4 P EA R L S
• Great care is taken not to violate the anterior/longitudinal ligament. The anterior longitudinal ligament should be identified before starting the diskectomy.
• Frequent fluoroscopic shots should be taken to ensure that instruments are not being past pointed into the abdomen.
Step 4
n
A radical diskectomy is performed under anteroposterior (AP) fluoroscopy. A
no.15 blade is used to incise the disk. Great care is taken not to violate the anterior/longitudinal ligament. The anterior longitudinal ligament should be identified before starting the diskectomy.
n
Subsequently, a small Cobb elevator is taken across the disk space under AP
fluoroscopy and is confirmed to pass just beyond the disk space. This is done with the aid of a mallet. Figure 34-6 is an AP fluoroscopic image showing a small Cobb elevator being passed into the disk space. Note the presence of the still-present guidewire, which is removed only after passing the small Cobb elevator initially into the disk space. Also note the retention pin, which secures the retractor, in this case, to the inferior vertebrae.
FIGURE 34-6 
322    Procedure 34| The Transpsoas Approach for Thoracolumbar Interbody Fusion
n
The Cobb elevator is then rotated to release the contralateral annulus. A small
Cobb elevator is passed all the way across to the contralateral annulus (Figure
34-7, A) and then rotated to release the annulus (Figure 34-7, B). This is critical
in correcting deformity. Subsequently, a larger Cobb elevator is used for the same procedure and to obtain greater release.
n
Care should be taken to avoid injury to contralateral neural and vascular struc-
tures when releasing the contralateral annulus.
n
A series of curettes (Figure 34-8, A), rasps (Figure 34-8, B), a uterine curette,
and rakes are used to radically excise the disk and prepare the end plates. This is once again performed under lateral fluoroscopic guidance.
A
FIGURE 34-7, A-B 
A
FIGURE 34-8, A-B 
B
B
Procedure 34  | The Transpsoas Approach for Thoracolumbar Interbody Fusion    323
S T E P 5 P EA R L S
• If the trial is bouncing while attempting insertion, this generally means that not enough of a diskectomy has been performed. The trial should be removed if it does not pass readily into the disk space, or more disk material should be removed.
• For dosing of RhBMP2/ACS, the authors use 2 to 4 mg in each polyether ether ketone (PEEK) cage.
• They also use demineralized bone matrix and pack it into the disk space before removing the retractor.
• In cases where the chest has been entered and the purse-string closure has been performed, the authors have not had to use chest tubes. Postoperative radiographs have shown the patient to have less than 10% pneumothorax, which can be monitored.
S T E P 5 P IT FA L L S
• Great care should be taken to preserve the anterior longitudinal ligament. If, at any point, there is a sudden give of the trial, most likely the anterior longitudinal ligament has been violated.
• If the anterior longitudinal ligament has been violated, the procedure can be salvaged by eventually directing the trials and cage more posteriorly. Great care, however, should be taken to avoid this situation, because any violation of the anterior longitudinal ligament puts the vascular and viscous structures at risk.
Step 5
n
Serial trials are then placed into the disk space, and positions are confirmed
under AP fluoroscopy.
n
After each trial, more disk material is removed.
n
The final trial should fit snugly into the disk space (Figure 34-9).
n
The disk space is then irrigated, and a polyether ether ketone (PEEK) spacer
filled with demineralized bone matrix and recombinant human bone morpho­genetic protein-2/absorbable collagen sponge (RhBMP2/ACS) (Infuse, Medtronic Minneapolis, Minn. Tenn.) is malleted into position.
FIGURE 34-9 
324    Procedure 34| The Transpsoas Approach for Thoracolumbar Interbody Fusion
n
AP (Figure 34-10, A) and lateral (Figure 34-10, B) fluoroscopy imaging confirms
placement of the spacer before the removal of the insertion handle. Figure
34-10, C is a photograph of the actual prosthesis in place.
n
The retractor is then removed. The retractor should be removed with the blades
open to visualize the retroperitoneal contents and ensure there is no bleeding. In addition, this ensures that any demineralized bone matrix placed does not come out into the retroperitoneal space.
n
In cases where the chest is entered, a red rubber catheter is inserted through
an incision communicating with the thoracic cavity. The thoracic incisions are all closed watertight.
• The incision through which the catheter is coming out is closed last with a purse-string stitch placed around the catheter.
• The anesthesiologist is asked to have the patient perform a Valsalva maneuver.
• At the same time, the catheter is connected to suction and then pulled out while the purse-string suture is closed in watertight fashion.
A
C
FIGURE 34-10, A-C 
B
Procedure 34  | The Transpsoas Approach for Thoracolumbar Interbody Fusion    325
P O S T OP E R AT IV E P I T F A L L S
• Complications commonly seen, such as thigh paresthesias and hip flexor and quadriceps weakness, are usually related to neural structures that have a close relationship to these muscles.
• Retroperitoneal structures, such as the ureter and kidney, can be injured, in addition to bowel and vasculature, although the rates of these injuries are probably significantly lower than in traditional abdominal approaches.
• If at any point there is excessive bleeding from this approach, the exposure can be readily converted to a laparotomy and/or thoracotomy.

Postoperative Care and Expected Outcomes

n
Typically, the authors will follow surgery, on the same day or on a different day,
with posterior fixation.
n
With a deformity correction, rotational deformity appears not to be corrected
using this methodology; rather, this can be corrected using pedicle screw instrumentation.
n
Postoperatively, a substantial portion of the patient’s complaint is of thigh
dysesthesias. These tend to improve with time and generally resolve.
n
A very small percentage of patients may have transient psoas or quadriceps
weakness. To minimize this risk, the authors avoid using a posterior blade, especially at L4-5. In addition, should there be any sustained neural irritation during the dilation stages of the muscle or placement of a retractor, they con­sider avoiding that level.
n
On several occasions, a nerve has been visualized in the field, and the authors
decided to perform interbody fusion by another approach.

Evidence

Anand N, Baron EM,  Thaiyananthan  G,  Khalsa K, Goldstein TB. Minimally  invasive 
multilevel percutaneous correction and  fusion  for  adult lumbar degenerative  scoliosis: a technique and  feasibility  study. J Spinal Disord  Tech 2008;21:459-67.
This is a technical paper reviewing the transpsoas technique, among other minimally invasive spine surgery (MISS) techniques used for circumferential deformity correction and fusion. Experience with 12 cases is reported. The mean surgical time for anterior procedures was 4.01 hours (standard deviation [SD]
1.88), and for posterior procedures, it was 3.99 hours (SD 1.19). The mean Cobb angle preoperatively was 18.93 degrees (SD 10.48), and postoperatively it was
6.19 degrees (SD 7.20).
Anand N, Rosemann R,  Khalsa  B,  Baron EM. Mid-term to long-term  clinical and 
functional outcomes of minimally  invasive  correction  and fusion for adults with  scoliosis. Neurosurg Focus 2010;28:E6.
This study presented a 22-month mean follow-up of 28 patients undergoing transpsoas lumbar interbody fusion as part of a minimally invasive deformity correction. The mean Cobb angle was 22 degrees (range 15 to 62 degrees), which corrected to 7 degrees (range 0 to 22 degrees). The major complications found were two patients with quadriceps palsies, from which they recovered within 6 months; one patient with a sustained retrocapsular renal hematoma; and one patient with an unrelated cerebellar hemorrhage. The authors concluded that minimally invasive surgical correction of adult scoliosis results in midterm to long-term outcomes similar to traditional surgical approaches. Whereas operating times are comparable with those achieved with open approaches, blood loss and morbidity appear to be significantly decreased in patients undergoing minimally invasive deformity correction.
Davis TT, Bae HW, Mok  MJ, Rasouli A, Delamarter RB. Lumbar Plexus  Anatomy 
within the Psoas Muscle: Implications for  the transpsoas Lateral Approach to the  L4-5 Disc. J Bone  Joint  Surg  Am. 2011 Aug 17;93(16):1482-7.
This article reviewed a neural structures of the lumbar plexus in the psoas muscle of 18 cadaveric specimens.
Ozgur BM, Aryan HE,  Pimenta  L,  Taylor WR. Extreme  Lateral Interbody Fusion 
(XLIF): a novel surgical  technique  for  anterior lumbar interbody fusion. Spine  J  2006;6:435-43.
This is an original-technique paper regarding the transpsoas approach. No complications were seen in the authors’ first 13 patients. The authors concluded that this approach allows anterior access to the disk space without using an approach surgeon or having the complications of an anterior intraabdominal procedure.
326    Procedure 34| The Transpsoas Approach for Thoracolumbar Interbody Fusion
Wang MY, Mummaneni PV. Minimally invasive  surgery for thoracolumbar spinal 
deformity: initial clinical experience  with  clinical  and radiographic outcomes.  Neurosurg Focus 2010;28:E9.
A retrospective study of 23 patients was undertaken to assess the clinical and radiographic results with minimally invasive surgery performed for adult thoracolumbar deformity. All patients underwent a lateral interbody fusion, followed by posterior percutaneous screw fixation and possible minimally invasive surgical transforaminal lumbar interbody fusion, if fusion near the lumbosacral junction was necessary. The mean follow-up was 13.4 months. Complications included two returns to the operating room, one for cerebrospinal fluid (CSF) leakage and the other for hardware pullout. In this study 30.4% experienced new thigh numbness, dysesthesias, pain, or weakness, and in one patient, these new symptoms were persistent.
P R O C ED U R E 3 5
Lumbar Total Disk
Arthroplasty
Michael F. Duffy and Jack E. Zigler
I N D I CAT I O NS P I T F A L L S
• Active systemic infection or infection localized to the site of implantation
• Osteopenia or osteoporosis defined as dual energy x-ray absorptiometry (DEXA) bone density–measured T-score less than 1.0
• Bony lumbar spinal stenosis
• Allergy or sensitivity to implant materials (cobalt, chromium, molybdenum, polyethylene, titanium)
• Isolated radicular compression syndromes, especially resulting from herniation

Indications

n
Symptomatic, single-level degenerative disk disease in the lumbar spine (L3-S1)
in skeletally mature patients with no more than grade I spondylolisthesis at the involved level and who have failed nonsurgical treatments for at least 6 months.

Examination/Imaging

n
Figure 35-1, A and B show flexion/extension lateral radiographs showing disk
height loss and degeneration at L5-S1. Note the absence of instability.
A
FIGURE 35-1, A-B 
B
328    Procedure 35| Lumbar Total Disk Arthroplasty
• Pars defect
• Involved vertebral end plate dimensionally smaller than 34.5 mm in the medial to lateral and/or 27 mm in the anterior to posterior directions
• Clinically compromised vertebral bodies at affected level because of current or past trauma
• Lytic spondylolisthesis or degenerative spondylolisthesis of grade greater than 1
• Scoliosis (lumbar curve greater than 11 degrees)
• Absolute contraindications for an anterior approach are significantly calcified aorta, and extensive abdominal wall reconstructions.
• Relative contraindications for the anterior approach are age, morbid obesity, previous intraabdominal or retroperitoneal surgery, history of severe pelvic inflammatory disease, and previous anterior spinal surgery.
FIGURE 35-2 
I N D I CAT I O NS
C O N T RO V E R S IE S
• Diagnosis of diskogenic syndrome by diskography is considered controversial by some authors.
• The upper limits of disk height loss for arthroplasty are not clearly defined.
T R E A T M E N T OP T I O N S
• Continued conservative treatment with medications, physical therapy, and injections
• Fusion of the involved segment— various techniques
• Artificial disk replacement at the involved level
FIGURE 35-3 
n
Use T2 weighted-sagittal magnetic resonance imaging (MRI) to document disk
degeneration (Figure 35-2).
n
Use axial MRI images to assess significant facet joint degeneration, which would
be a contraindication for arthroplasty.
n
Perform preoperative DEXA scan to verify adequate bone density (T-score greater
than 1.0) before the procedure.
n
Figure 35-3 is a computed tomography (CT) diskogram showing morphologic
changes at L5-S1; the patient reported 10/10 concordant pain. The L4-5 level was normal with minimal discomfort.