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S T E P 3 C ON T R O V ER S I E S
• Necessity of complete reduction
S T E P 4 P EA R L S
• Fluoroscopic guidance
S T E P 4 I MP L A N T A T I O N /
I N S T RU M E N T A T I O N
• Cruciate reamer (Figure 30-9)
• Titanium mesh cage
Procedure 30  | Surgical Treatment of High-Grade Spondylolisthesis    289
FIGURE 30-7 
A
C
FIGURE 30-8, A-C 
B
FIGURE 30-9 
290    Procedure 30| Surgical Treatment of High-Grade Spondylolisthesis
L5
L4 screw
Gap closed
S1 screw
FIGURE 30-10 
S T E P 5 P EA R L S
• Neuromonitoring during osteotomy closure
S T E P 5 P IT FA L L S
• Overreduction
S T E P 5
I N S T RU M E N T A T I O N /
I M P L AN TAT IO N
• Transforaminal lumbar interbody fusion (TLIF) graft in vertebrectomy defect
FIGURE 30-11 
Step 5
n
Gaines procedure (L5 vertebrectomy) (Figure 30-10)
n
Posterior closure of resected segment (Figure 30-11)
Procedure 30  | Surgical Treatment of High-Grade Spondylolisthesis    291
P O S T OP E R AT IV E P E A R L S
• Aggressive physical therapy is crucial to recovery.
P O S T OP E R AT IV E P I T F A L L S
• Patient with significant neurologic deficit should be immediately taken back to operating room for reduction of correction.
P O S T OP E R AT IV E
I N S T RU M E N T A T I O N /
I M P L AN TAT IO N
• Immediate postoperative AP/lateral plain radiographs
• CT scan if new neurologic deficit
• Standing anteroposterior (AP)/lateral 36-inch scoliosis radiographs before discharge to assess sagittal balance
P O S T OP E R AT IV E
C O N T RO V E R S IE S
• Mild postoperative weakness may or may not require return to operating room.

Postoperative Care and Expected Outcomes

n
Complete blood count (CBC), chemistry panel
n
Pain control (patient-controlled analgesia [PCA])
n
Neurologic monitoring (q 2 hr neurologic checks × 24 hours)
n
Anticoagulation postoperative day (POD) 2

Evidence

Gaines RW. L5 vertebrectomy for  the surgical treatment of spondyloptosis: thirty 
cases in 25 years.  Spine  2005;30(Suppl  6):S66-70.
Hanson DS, Bridwell KH,  Rhee  JM,  et al. Correlation of pelvic  incidence with 
low- and high-grade isthmic  spondylolisthesis.  Spine  2002;27:2026-9.
Labelle H, Roussouly P, Berthonnaud E, et al.  Spondylolisthesis, pelvic  incidence, 
and spinopelvic balance: a  correlation  study. Spine 2004;29:2049-54.
Lehmer SM, Steffee AD, Gaines RW Jr. Treatment of L5-S1 spondyloptosis by 
staged L5 resection with  reduction  and  fusion of L4 onto S1  (Gaines procedure).  Spine 1994;19:1916-25.
Ogilvie JW. Complications in spondylolisthesis  surgery. Spine 2005;30(Suppl  6): 
S97-101.
Sailhan F, Gollogly S, Roussouly P. The radiographic results and neurologic 
complications of instrumented reduction  and  fusion  of high-grade  spondylolisthesis without decompression of  the  neural  elements: a retrospective  review of 44 patients.  Spine  2006;31:161-9;  discussion 170.
Smith JA, Deviren V, Berven S, et al. Clinical outcome of  trans-sacral interbody 
fusion after partial reduction  for  high-grade  L5-S1 spondylolisthesis. Spine  2001;26:2227-34.
P R O C ED U R E 3 1
Interspinous Process
Motion-Sparing Implant
Christopher F. Wolf, Mark M. Mikhael,
and Arya Nick Shamie
I N D I CAT I O NS P I T F A L L S
• Symptoms unresolved with lumbar flexion
• Axial back pain as the main complaint (versus buttock and/or leg pain)
• Osteoporosis with recent history of fragility fracture (severe osteoporosis)
• Spondylolisthesis greater than 25% on static or dynamic radiographs
• Significant scoliosis (greater than 25 degrees at the level of stenosis)
• Ankylosis of the involved segment

Indications

n
Lumbar stenosis at one or two levels
• Central stenosis
• Lateral recess stenosis
• Foraminal stenosis
• Facet hypertrophy and cyst formation
n
Patient must report a resolution of symptoms when seated or flexed forward
(i.e., “shopping cart” sign) when upright.

Examination/Imaging

n
Standing anteroposterior (AP), lateral (neutral, extension [
[
right
]) views (Figure 31-1)
left
] and flexion
FIGURE 31-1 
Figures 31-3, 31-5, 31-6, and 31-8 © 2011 Medtronic Spine, LLC. Used with permission.
I N D I CAT I O NS
C O N T RO V E R S IE S
• “Mild to moderate” stenosis indication for ISP implantation refers to patients’ symptoms (able to walk at least 50 feet), not the MRI findings.
• Although studies show that
claudication in patients with severe stenosis (on magnetic resonance imaging [MRI]) can be helped with ISP implants, some surgeons reserve this device for mild to moderate stenosis (on MRI) patients only.
• Three-level implantation of the device is not currently approved. Some surgeons have had success with treatment of three-level stenosis with ISP implantation.
T R E A T M E N T OP T I O N S
• Nonsurgical management, that is, physical therapy, epidural steroid injections, and so forth
• Laminectomy without fusion or with fusion in setting of spondylolisthesis
• Anterior versus lateral interbody fusion alone with indirect decompression
• Disk arthroplasty
Procedure 31  | Interspinous Process Motion-Sparing Implant    293
FIGURE 31-2 
P O S I TI O N I N G PE A R L S
• Radiolucent table
• Ensure patient positioning with hips and knees flexed to accentuate lumbar flexion; this position will splay the spinous processes, aiding in ease of insertion of the ISP device.
P O S I TI O N I N G PI T FA L L S
• Inadequate imaging: Use AP and lateral fluoroscopy to confirm, before incision, that desired views can be obtained.
P O S I TI O N I N G EQ U I P M EN T
• Bean bag with adequate padding for all bony prominences
• Secure patient with straps, especially for procedures done under conscious sedation/local anesthetic.
FIGURE 31-3 
• If patient has grade 2 spondylolisthesis on static or dynamic films, that condi­tion is considered a contraindication to the interspinous process (ISP) procedure.
n
MRI with axial, sagittal, and coronal imaging to assess disk herniation, canal
stenosis, and Modic changes (Figure 31-2)

Surgical Anatomy

n
Midline skin incision with bilateral fascial incision exposing the inferior and
superior aspects of the spinous processes at the selected interspinous segment (Figure 31-3)
n
Careful preservation of the supraspinous ligament
n
Avoiding disruption of the facet joint anatomy
294    Procedure 31| Interspinous Process Motion-Sparing Implant

P O S I TI O N I N G

C O N T RO V E R S IE S
• Appropriate lumbar flexion for lateral positioning
• Maximum flexion obtained with lateral decubitus versus prone positioning

P O RTA L S / E X P O S U R ES

P E A R LS
• If operating at the L4-5 level, avoid an incision directly over the prominent L4 spinous process, and deviate slightly more caudad to center on the interspinous space.
• Hypertrophic facet capsules need to be trimmed to position the implant as anterior as possible.
P O RTA L S / E X P O S U R ES
P I T F A L L S
• Ensure the patient is adequately secured to the bed with straps.
• If the facet capsule is hypertrophic, the implant will be placed too posteriorly, compromising its efficacy and increasing the risk of implant dislodgement.
Positioning
n
Lateral positioning on radiolucent table (Figure 31-4)
n
Prone positioning on a Jackson table with a Wilson frame for maximal flexion
at the index level
Portals/Exposures
n
Make a midline incision.
n
Perform blunt subperiosteal dissection with Cobb elevator, avoiding excessive
muscle injury.
n
Avoid injury to the supraspinous ligament as well as the facet anatomy.
n
Remove excessive spinous process osteophytes with rongeur.

Procedure

Step 1:  Positioning
n
The lateral position can be used in combination with conscious sedation and
local anesthetic (see Figure 31-4).
n
General anesthesia and prone positioning is also appropriate if a Wilson frame
is used.
Step 2:  Incision
n
Make a midline skin incision with bilateral fascial incision exposing the inferior
and superior aspects of the spinous processes at the selected interspinous segment (Figure 31-5).
P O RTA L S / E X P O S U R ES
E Q U I PM E N T
• Cobb elevator
• Large right-angled Gelpi retractor
S T E P 1 P EA R L S
• In patients with high anesthetic risk, the lateral position can be used in combination with conscious sedation and ample local anesthetic, avoiding general anesthesia.
S T E P 2 P EA R L S
• If operating at the L4-5 level, avoid an incision directly over the prominent L4 spinous process, and deviate slightly more caudad to center on the interspinous space.
S T E P 2 P IT FA L L S
• An incision too cephalad, making implant insertion more difficult
FIGURE 31-4 
FIGURE 31-5 
Procedure 31  | Interspinous Process Motion-Sparing Implant    295
S T E P 3 P EA R L S
• All implants have specific dilators for their respective system. It is important to become familiar with them before the procedure.
S T E P 3 P IT FA L L S
• Ensure, radiographically, the correct level, as well as that the dilators and sizers for the interspace are positioned sufficiently anteriorly, just posterior to the spinolaminar junction.
• Avoid overdilating, because this may lead to fracture of the spinous processes or rupture of the interspinous/supraspinous ligaments.
S T E P 4 P EA R L S
• When sizing, the interspace tension in the supraspinous ligament should be developed until the sizing device has two-finger resistance; oversizing the implant should be avoided.
Step 3:  Preparing Interspace
n
Develop the interspinous space with the small and large dilators, and confirm
the position on a radiograph (Figure 31-6).
n
Gradually increase the space by dilation using the sizer until it is noted, clinically,
that the interspinous ligament is taut (sometimes a “vacuum disk” is noted radiographically at the posterior aspect of the disk space, confirming a disk space distraction) (Figure 31-7).
Step 4:  Implantation
n
Select the appropriate implant size based on the sizing trials.
n
Each implant has unique fixation methods that should be clearly understood by
the surgeon before the procedure (Figure 31-8).
S T E P 4 P IT FA L L S
• Do not overstuff the interspace with too large an implant, because this may stress the spinous processes and result in a delayed fracture caused by superphysiologic forces on the spinous processes.
FIGURE 31-7  FIGURE 31-8
FIGURE 31-6 
296    Procedure 31| Interspinous Process Motion-Sparing Implant
P O S T OP E R AT IV E P E A R L S
• Most patients state that their preoperative claudication pain is relieved immediately after surgery.
• Inadequate preoperative symptom relief should be evaluated with further imaging and may potentially require additional therapy, including physical therapy and at-time epidural steroid injections.
• If patient continues complaining of axial low back pain, they should be reminded that the surgery was to address their buttock and leg pain; once the leg and buttock pain is relieved, the patient may start complaining of the remaining low back pain.
P O S T OP E R AT IV E P I T F A L L S
• Although rare, any neurologic change occurring abruptly postoperatively should signal immediate evaluation by the surgeon, because dislodgement, fracture, disk herniation, and infection are a concern.

Postoperative Care and Expected Outcomes

n
The patient can mobilize postoperatively with adequate analgesia.
n
A 2-week follow-up should be done for wound evaluation as well as standing
AP and lateral radiographs to ensure maintained implant positioning.

Evidence

Christie S, Song J,  Fessler  R.  Dynamic interspinous process technology. Spine 
2005;30(Suppl 16):S73-8.
This article is an overview of interspinous technology.
Kabir SM, Gupta SR,  Casey  AT. Lumbar interspinous spacers: a systematic review of 
clinical and biomechanical evidence.  Spine  2010;35:E1499-506.
This is a review of the biomechanical and clinical evidence related to interspinous spacer technology.
Kim D, Albert T. Interspinous process spacers. J Am Acad Orthop  Surg 2007;15: 
200-7.
This article is an overview of interspinous technology.
Siddiqui M, Nicol M,  Karadimas  E,  et al. The positional magnetic  resonance 
imaging changes in the  lumbar  spine  following insertion of a novel  interspinous  process distraction device. Spine  2005;30:2677-82.
This article reports the MRI changes before and after interspinous process implantation.
Weiner BK. Interspinous  process decompression system device affords superior 
outcomes and equal safety  to  non-operative  therapy. Spine 2005;30:2846-7.
The article highlights the clinical advantages of the interspinous spacer over nonoperative therapy.
Zucherman JF, Hsu KY, Hartjen CA, et al.  A multicenter, prospective, randomized 
trial evaluating the X  STOP  interspinous  process decompression system for the  treatment of neurogenic intermittent  claudication:  two-year  follow up results.  Spine 2005;30:1351-58.
This a Level I research paper evaluating the 2-year results of interspinous process spacer implantation for neurogenic intermittent claudication.
P R O C ED U R E 3 2
Anterior Lumbar
Interbody Fusion
Michael D. Daubs
I N D I CAT I O NS P I T F A L L S
• Prior anterior lumbar surgery
• Prior anterior abdominal surgery (retroperitoneal)
• Peripheral vascular disease/vessel calcification
• Osteopenia
• Morbid obesity

I N D I CAT I O NS

C O N T RO V E R S IE S
• Males have a 2% to 5% risk for retrograde ejaculation with the anterior lumbar approach.
Indications
n
Lumbar degenerative disk disease
n
Anterior column support in long fusion constructs
n
Restoring lumbar lordosis
n
Pseudarthrosis following posterior lumbar fusion
n
Lumbar fusions at high risk for nonunion
n
Tumor and trauma

Examination/Imaging

n
Use magnetic resonance imaging to assess degree of disk degeneration (Figure
32-1).
n
Obtain a standing lateral radiograph of the lumbar spine to assess whether the
sacral slope and L5-S1 disk are at an angle that can be accessed through the anterior approach (Figure 32-2). If the sacral slope is severe (L5-S1 spondylo­listhesis), access to the disk can be very difficult.
FIGURE 32-1 
FIGURE 32-2 
298    Procedure 32| Anterior Lumbar Interbody Fusion
Inferior vena cava
Median sacral
vessels
L5, S1 disc
FIGURE 32-3 
Aorta
Superior hypogastric plexus
Iliac arteries
Left common iliac vein
T R E A T M E N T OP T I O N S
• Posterior intertransverse fusion
• Posterior lumbar interbody fusion
• Transforaminal lumbar interbody fusion
• Direct lateral transpsoas lumbar interbody fusion
P O S I TI O N I N G PE A R L S
• A bolster can be used in the lumbar region to accentuate lordosis as needed.
P O S I TI O N I N G PI T FA L L S
• If using fluoroscopy, obtain images preoperatively to ensure that all views are obtainable without obstruction from the table or the patient’s extremities.
P O S I TI O N I N G EQ U I P M EN T
• An operating room table that can rotate side to side can be helpful for visualization during the approach.

Surgical Anatomy

n
Aorta, vena cava, iliac veins and arteries (Figures 32-3 and 32-4)
n
Ureter
n
Sympathetic nerves
n
Hypogastric plexus

Positioning

n
The patient is positioned supine on a radiolucent operating room table.
n
The patient’s arms are positioned at the sides in an abducted position on rests
to allow lateral imaging (Figure 32-5).

Portals/Exposures

n
A lateral fluoroscopic image is used to mark the level of incision.
n
A radiopaque rod or pin is used to mark the angle of the disk and the corre-
sponding trajectory to the abdominal wall. The incision site is adjusted to give optimum access to the disk to be operated upon.
n
A transverse or longitudinal incision is made a few centimeters lateral to midline
at the corresponding disk level, in line with the angle of the disk space. Figure
32-6, (
line A
) shows the more vertical approach to L4-5 and a higher incision level, and Figure 32-6, ( levels are being addressed, the incision should be between the levels, or a longitudinal incision can be used.
n
The anterior rectus sheath is incised transversely, while avoiding the underlying
rectus muscle.
n
The transversalis fascia is gently incised with a no. 15 scalpel, and the interval
between the peritoneum and fascia is developed.
n
The retroperitoneal cavity is dissected bluntly toward the midline (left to right),
and the peritoneal contents are retracted to expose the anterior spine.
line B
) displays the trajectory to the L5-S1 disk. If both