
- •Federal State Budgetary Educational
- •The pancreas is a parenchymal organ located retroperitoneally. Performs two main functions exocrine
- •1) painful (in the epigastrium, shingles, after taking
- •- signs of diabetes mellitus: weakness, sweating due to the development of hypoglycemia.
- •abdomen in a patient with CP:
- •Pain points and zones detected by palpation in patients with chronic pancreatitis:
- •The projection of the pancreas on the abdominal wall.
- •Areas of cutaneous hyperesthesia with involvement of the head (1), body (2) and
- •Visceral pain (shaded) and the direction of pain irradiation in chronic pancreatitis (Mazatka
- •Acute pancreatitis (АP):
- •Etiology:
- •- Sudden, severe pain at the top half of the abdomen, often encircling,
- •Forced position of a patient with acute pancreatitis:
- •1.Acute vascular insufficiency (shock, collapse)
- •Chronic pancreatitis (CP) is an inflammatory disease of the pancreas, characterized by subtotal
- •7.Hereditary predisposition
- •Clinical classification:
- •By etiology:
- •CP in the acute phase:
- •pain in CP:
- •II. Exocrine pancreatic insufficiency leads to disruption of the processes of intestinal digestion
- •Exocrine pancreatic insufficiency is associated with the following mechanisms:
- •III. Endocrine insufficiency symptom
- •-weight loss,
- •There may be a symptom of "red droplets" or a symptom of Tuzhilin:
- •1) serum amylase level (after 2-12 hours from the onset of exacerbation, maximum
- •caused by:
- •in the duodenal contents obtained by a double probe is investigated
- •and GGTP (gamma-glutamyl transpeptidase) - partial or complete obstruction of the biliary tract
- •Radiography: duodenal stenosis in chronic pancreatitis:
- •10)Ultrasound: allows you to identify the nature and extent of the pathological process
- •Ultrasound for chronic pancreatitis:
- •Computed tomography (norm):
- •Endoscopic retrograde cholangiopancreatography:
- •Shock (hypovolemic) (blood pressure is low, expressed pain syndrome, tachycardia, pallor of the
- •exacerbation of CP with necrosis) Clinic: fever, abdominal pain, chills, tension of the
- •small and large intestines: Syndrome of insufficient absorption (malabsorption syndrome) is a violation
- •deficiency, which leads to impaired absorption of a particular substance: intolerance to disaccharides;
- •Secondary (acquired) - decrease (disruption) many enzymes and malabsorption of many nutrients:
- •of fat metabolism include:
- •carbohydrate absorption include: hypoglycemia that occurs after taking concentrated solutions of sugar, milk,
- •symptom complex (SNP), caused by a violation of the digestion of nutrients due
- •formation, impaired absorption and removal of gases.
- •Irritable bowel syndrome:
- •characterized by a variety of clinical manifestations. During an attack - stabbing pain
- •Thank you for Attention!

Radiography: duodenal stenosis in chronic pancreatitis:

10)Ultrasound: allows you to identify the nature and extent of the pathological process in the pancreas, an increase and change in the density of the pancreas, calcifications, pseudocysts, etc.
11)computed tomography: foci of necrosis, calcifications and pancreatic cysts
12)ERPHG - endoscopic retrograde cholangiopancreatography, this method increased the accuracy of CP and expanded the therapeutic possibilities.

Ultrasound for chronic pancreatitis:

Computed tomography (norm):

Endoscopic retrograde cholangiopancreatography:
Increased intrapancreatic pressure due to pancreatic duct stenosis
Two areas of pronounced narrowing of the main RV duct, followed by post- stenotic expansion

Shock (hypovolemic) (blood pressure is low, expressed pain syndrome, tachycardia, pallor of the skin, cold sweat, cyanosis, oliguria, stupor)
2.went. - kish. bleeding (from varicose veins of the esophagus and cardiac section of the stomach, resulting from thrombosis of the splenic vein, with the breakthrough of pseudocysts or abscesses in the intestine).
3.Stenosis of the distal common bile duct
4.Obstructive jaundice, cholangitis (mb -

exacerbation of CP with necrosis) Clinic: fever, abdominal pain, chills, tension of the anterior abdominal wall, leukocytosis
6. Pancreatic ascites.
FATAL OUTCOME in CP is associated with two groups of causes
1 - complications of CP - shock, abscesses, sepsis, massive GI - bleeding, complications of diabetes
2 - a combination of CP + damage to other organs and systems. So chronic alcoholism, along with CP, develops CP, affecting. heart, lungs, which can be the immediate cause of death.

small and large intestines: Syndrome of insufficient absorption (malabsorption syndrome) is a violation of the processes of absorption (absorption) of one or more nutrients in the small intestine.
Malabsorption syndrome can be: primary and secondary.

deficiency, which leads to impaired absorption of a particular substance: intolerance to disaccharides;
gluten enteropathy - peptidase deficiency; intolerance to monosaccharides (glucose, fructose); violation of the absorption of vitamin B12 - folic acid;
impaired absorption of amino acids (Hartnap syndrome, cystinuria - hereditary disorders of tryptophan absorption in the small intestine)

Secondary (acquired) - decrease (disruption) many enzymes and malabsorption of many nutrients:
-gastrogenic (after gastrectomy);
-pancreatogenic;
-hepatogenic;
-enterogenic;
-parasitic;
-vascular bowel disease;
-endocrine (diabetes, thyrotoxicosis, hypothyroidism);
-iatrogenic (postoperative).