РУДН
2018
Воспалительная болезнь кишечника (ВБК) – это группа идиопатических хронических воспалительных состояний кишечника.
environment
diet
possibly genetics
bacteria
a virus
or a protein in food
Diarrhea Constipation
Bowel movement abnormalities Abdominal cramping and pain Nausea and vomiting
World Gastroenterology Organization (WGO)
|
Ulcerative colitis |
Crohn’s disease |
Incidence |
11/100 000 |
7/100 000 |
Age of onset |
15-30 & 60-80 |
15-30 & 60-80 |
Male:female ratio |
1:1 |
1,1-1,8:1 |
Smoking |
May prevent |
May cause disease |
|
disease |
|
Oral contraceptive |
No increased risk |
Relative risk 1,9 |
Appendectomy |
Not protective |
Protective |
Monozygotic twins |
8% concordance |
67% concordance |
Crohn's disease differs from UC in the areas of the bowel it involves - it most commonly affects the last part of the small intestine and parts of the large intestine.
Crohn's disease isn't limited to these areas and can attack any part of the digestive tract
Aphthousus
ulcers
Segmental distribution of ulcers
Cobblestone |
Strictures due |
appearance |
to fibrosis |
