підручники. біохімія / Uchebnik_po_Biokhimii_E_S_Severin

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2. HiJbl - cneu,llfjJU'leCKUe JlUlQHObl

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5 cneuHQlH'leCKHXD.HCYJih<i>H)lHbIX cmJJett (B 3aBHCHMOCTH OT BH)la TOKCHHa). Cpo,UCTBO HeiilpoTOKCHHOB K XOJIHHepr11qecKHM peuerrTopaM OlJeHb BhICOKO (KnHcc = 10-11 ). Ol!eBH)lHO, Me)J()ly TOKCH-

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HA nP~MEPE rEMornoEi~HA

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A. CTPYKTYPA II ct>YHKUIIII MIIOfJIOBIIHA

Mttorno6HH OTHOC5IT K KJlaccy reMCO)lep)KaWHX 6eJlKOB, T.e. OH CO)lep)KHT npoCTeTH'leCKYTO rpynny - reM, llOBOJlhHO rrpo'IHOCB5l3aHHYTO c 6eJlKOBOH lJaCTbTO. M HOfJl06HH OTHOC51T K rno6yll51PHblM 6eJlKaM; OH HMeeT TOJlhKO OllHY noJlHnenTHllHYTO uenh.

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2. Cmpoeuue MUOl.!loouua

M11orno611H coLI,ep)KHT He6eJlKOByIO 'laCTh(reM) H 6eJlKOBYIO '!aCTh(anOMHOfJl06HH).

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CB513aHhI lJeTblpbM.H KOOp)lHHaUHOHHbIMH CB51-

351MH c Fe2+, HaxOMWHMC51 B ueHTpe MOJleKy-

JihI (pHC. 1-29).

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ny6nemu1 Me)l()J:y ABYMH a-c1rnpanHMH F 11 E.

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Ii. CTPYKTYPA H Cl>YHKQHH fEMOfJIOBHHA

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PMC. 1-30. Pacnono>KeHMe reMa B BKTMBHOM L\9HTpe anOMMorno6MH8 MnpoToMepoa anoreMorno6MHa.

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1. I'eMOM06UHbl 'le.ll06e1Ca

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B 3PHTpOUMTax B3pocnoro 'IeJioBeKareMorno611H COCTaBJUieT 90% OT Bcex 6eJIKOB .uaHHOH KJieTKM.

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(2a2p).

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I'eMomo6uuF - cpeTaJihHhIH reMorno611H, c11me311pyeTCH B rreqemf 11 KOCTHOM M03re IIJIO)J,a .uo rrep110.ua ero po)J()J;eHMH. HMeeT TeTpaMepHYJO CTpYKTYPY, COCTOHJUYIO 113 2 a- 11 2 y-uerreH:. Iloc.Jie po)!(UeHMH pe6ettKa rrocTerretttto JaMemaeTcH Ha reMorno611H A, KOTOphIH Ha'I11HaeTc11H-

Te3HpoBaTbCH B KJieTKax KOCTHOro M03ra ~e Ha

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2. Cmpoenue zeMoMo6una A

CTJJoeuue npoTOMepos reMorJio6uua

KoHcpopMau11H oT.ue.JihHhIX rrpoToMepoB reMorno611tta y.u11B11TeJibHO HarroM11ttaeT Kott¢>opMau1110 Ml10rno611tta, HeCMOTpH Ha TO, qTO B rrepB11qttoH CTPYKTYPe HX rro.JI11rrerrTHUHhIX uerreH: 11,UeHTlfqHbI TO.JlbKO 24 aMl1HOKMCJIOTHbIX OCTaTKa. IlpoTOMepbI reMorno611tta, TaK )Ke KaK 11 arrOMl10fJI0611H, COCTOHT 113 8 crr11paneti, CBepHYThIX B IIJIOTHYJO rno6y-

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IIJieKC, 4eM MHOf.JIOforn.

PoJib rucTu.uuua E7 B fi>YHKUHOHHposauuu MHOfJIOOHHa H reMOfJIOOHHa

feM HMeeT BbICOKOe cpo.ucrno K OKCHUY yrne-

po.ua (CO). B BO)J,HOH cpe.ue CB060)J,HbIH OT 6e.JIKOBOH qaCTl1 reM CBH3bIBaeTCH c co B 25 000 pa3 CMJibHee, qeM Or BhICOKaH cTerreHb cpo.ucrna reMa K co ITO cpaBHeHl1IO c 02 o6bHCHHeTCH pa3HbIM rrpocTpaHCTBeHHbIM pacrrO.JIO)l(eH11eM KOMIIJieKCOB Fe2+ reMa c CO 11 0 2 (pHc.

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HMH 0 2 (pwc. B pe3y.JihTaTe cpo.ucrno reMa K CO B 6e.JIKax Bcero B 200 pa3 rrpeBhilllaeT ero cpon:crno K 0 2.

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paBJleH 1151.

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u~

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nap1..1111anbHOe ,1:18Bfl0Hli1e 02, MM pT. CT.

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