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ECHO 2013 / When (and how) to use Stress Testing in Valvular Heart Disease

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When and how to use stress testing in valvular heart diseases

Jae K. Oh, MD

State of the Art Echo in New York City April 3rd, 2013

Disclosure : Echo Core Lab for Core Valve Pivotal Trial

©2013 MFMER | 3259292-1

Valvular heart disease is usually considered static.

Its management relies upon resting evaluation only.

Most valve diseases have a dynamic component

©2013 MFMER | 3259292-2

82 year old man with exertional dyspnea

Previously healthy other than HTN in the last 2 yrs, treated by ACEI and diuretics

Progressive shortness of breath on exertion in the last 2 yrs

Had negative echo, angiogram and LV cath from outside

©2013 MFMER | 3259292-3

82 year old man with dyspnea soon after treated for hypertension

Normal coronary angiogram and stress test

©2013 MFMER | 3259292-4

Before and After exercise

Resting

Exercise

What is the mechanism ?

©2013 MFMER | 3259292-5

LVOT gradient before and after exercise

5 m/s

Baseline

Exercise

©2013 MFMER | 3259292-6

Repeat Echo 2 months later D/C of ACE i and Lasix Addition of Beta blocker

Rest

Exercise

©2013 MFMER | 3259292-7

LVOT gradient before and after exercise After change in Rx

Resting

Exercise

 

©2013 MFMER | 3259292-8

Stress Echo in VHD

In Asymptomatic Severe VHD or Symptomatic Non-severe VHD

 

Parameters

AHA/ACC Guideline

AS

Symptoms

Class II b (1 ESC)

 

Fall in BP

Class II b (II a)

 

↑ ∆ Pmean ≥15-20mmHg

 

 

↓ LVEF

 

AR

Symptoms

 

 

↓ LVEF

 

MS

Symptoms

Class 1 C

 

PASP>60mmHg

Class 1 C

 

∆ Pmean >15mmHg

Class 1 C

MR

Symptoms

Class II a

 

PASP >60mmHg

 

 

↓LVEF ≥ 4%

 

©2013 MFMER | 3259292-9

53 year old woman with Dyspnea s/p MV Balloon Valvuloplasty

Mean Gradient

7 mmHg

Heart rate

69 BPM

TR velocity

2.8 m/sec

 

 

©2013 MFMER | 3259292-10