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ECHO 2013 / When (and how) to use Stress Testing in Valvular Heart Disease

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Change in MR Volume with Exercise Degenerative MV Disease

Magne, J. et al. JACC 2010;56:300-9

©2013 MFMER | 3259292-31

Symptom-free survival

SPAP at rest and during exercise

Exercise PHT is associated with markedly low

2-year symptom-free survival, emphasizing the use of exercise echocardiography.

An exercise SPAP>56mmHg accurately predicts the occurrence of symptoms.

Magne, J. et al. Circulation 2010;122:33-41

©2013 MFMER | 3259292-32

Prosthetic Heart Valves

Normally and abnormally functioning prosthesis can produce similar estimated gradients at rest by TTE

Stress echo may be valuable in confirming or excluding the presence of hemodynamically significant prosthetic valve stenosis or PPM

Discordance between patient’s symptomatic status and the prosthetic valve hemodynamics measured at rest

©2013 MFMER | 3259292-33

Exercise Echocardiography and

Prosthetic Heart Valves

Mean gradient (mm Hg)

Aortic Prosthesis

140

120

100 Exercise

80

60

Patient #1

 

40

Patient #2

20

Rest

0

0.4

0.8

1.2

1.6

Mitral Prosthesis

70

60

50 Exercise

40

 

30

 

20

Patient #3

 

10

Patient #4

 

0

Rest

 

2.0 0.4 0.8 1.2 1.6 2.0

Indexed EOA (cm2/m2)

Indexed EOA (cm2/m2)

Picano et al: JACC 54:2251, 2009

©2013 MFMER | 3259292-34

Disproportionate increase in transvalvular gradient >20 mmHg for aortic prostheses

or

>12mmHg for mitral prostheses indicates severe

prosthesis dysfunction or PPM

Picano et al. JACC 2009;54:2251-60

©2013 MFMER | 3259292-35

Increasing exertional dyspnea after mitral valve repair

©2013 MFMER | 3259292-36

Exercise Echo Doppler after Mitral Valve Repair

©2013 MFMER | 3259292-37

60 year old woman with exertional dyspnea and new atrial fibrillation

©2013 MFMER | 3259292-38

60 year old woman with exertional dyspnea and new paroxysmal atrial fibrillation

©2013 MFMER | 3259292-39

60 year old woman with exertional dyspnea and new atrial fibrillation

©2013 MFMER | 3259292-40