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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3908_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Foreword
- •Foreword
- •Foreword
- •Preface
- •Acknowledgments
- •About the Book
- •Contents
- •Contributors
- •References
- •2.3.1 Component Therapy
- •2.3.1.1 Tranexamic Acid
- •2.3.1.3 Factor Concentrate-Based Resuscitation Strategies
- •2.3.1.4 Factor VIIa
- •Conclusion
- •References
- •3.1 Blunt Cerebrovascular Injuries
- •3.4 Medical Treatment
- •3.5 Endovascular Treatment
- •3.6 Penetrating Cervical Vascular Injuries
- •References
- •4.1 Introduction
- •4.2 Initial Evaluation
- •4.3 Line Placement Considerations
- •4.5 Embolization Agents
- •4.6 Gelfoam
- •4.7 Particles
- •4.8 Metallic Coils
- •4.9 Amplatzer Vascular Plugs
- •4.10 Liver Endovascular Embolization
- •4.11 Spleen Endovascular Embolization
- •4.12 Kidney Endovascular Embolization
- •4.13 Pelvic Endovascular Embolization
- •4.14 Endovascular Stent Grafts
- •4.15 Axillosubclavian Injuries
- •4.16 Thoracic Endovascular Aortic Repair
- •Conclusion
- •Expert’s Comments by Yoram Kluger
- •References
- •5.1 Introduction
- •5.2 Endovascular Damage Control
- •5.3 Lower Extremity Vascular Injuries
- •5.3.1 Common Femoral Artery
- •5.3.2 Profunda Femoris
- •5.3.3 Superficial Femoral Artery
- •5.3.4 Popliteal Artery
- •5.3.5 Infrapopliteal Arteries
- •5.4 Venous Injuries
- •5.6 Upper Extremity Vascular Injuries
- •5.6.1 Axillo-subclavian Arteries
- •5.7 Postoperative Care
- •References
- •6.1 Introduction
- •6.2 History
- •6.3 Indications
- •6.4 Procedure
- •6.4.1 Arterial Access
- •6.4.3 Sheath Placement
- •6.4.5 Management While Occluded
- •6.4.6 Balloon Deflation
- •6.5 Current Research
- •Conclusion
- •Expert’s Comments by Catherine Arvieux
- •References
- •7: Partial REBOA
- •7.1 Introduction
- •7.2 Physiology
- •7.6 Feasibility
- •7.7 Future Directions
- •Conclusion
- •References
- •8.1 Introduction
- •8.2 Traumatic Brain Injury
- •8.2.1 Epidemiology
- •8.2.2 Normal Brain Physiology
- •8.2.3 Pathophysiology After Traumatic Brain Injury
- •8.4 Future Directions
- •Expert’s Comments by Edoardo Picetti
- •References
- •9.1 Introduction
- •9.4 Mitigation Strategies
- •9.4.2 Balloon Occlusion Time
- •9.4.3 Partial REBOA
- •9.4.4 Pharmacologic Interventions
- •9.4.5 Nitric Oxide Inhibitors
- •9.4.6 Valproic Acid
- •9.4.7 Adenosine
- •9.4.8 Heme Oxygenase
- •9.4.9 Statins
- •9.4.10 Hypothermia
- •Conclusion
- •References
- •10.1 Introduction
- •10.3.2 Clinical Evidence
- •References
- •10.2 Nontraumatic Cardiac Arrest
- •10.2.1 Epidemiology
- •10.2.2 Physiology
- •10.3.1 Preclinical Studies
- •10.3.1.1 Intermittent Occlusion
- •10.3.1.2 Continuous Occlusion
- •10.3.1.3 Selective Aortic Arch Perfusion
- •11.1 Introduction
- •11.3 Uterine Blood Supply
- •11.5 First Trimester
- •11.5.1 Ectopic Pregnancy
- •11.5.2 Molar Pregnancy
- •11.6.1 Placental Abruption
- •11.6.2 Trauma
- •11.6.3 Postpartum Hemorrhage
- •11.6.4 Placenta Accreta Spectrum
- •11.8 Massive Transfusion Protocols
- •11.9 Adjunctive Medications
- •11.9.1 Tranexamic Acid
- •11.9.2 Lyophilized Fibrinogen Concentrate
- •11.9.3 Prothrombin Complex Concentrates (PCCs)
- •11.9.4 Activated Recombinant Factor VII
- •11.10 Endovascular Balloon Occlusion
- •References
- •12.1 Introduction
- •12.2 Prehospital EVTM
- •12.3 Austere EVTM
- •Conclusion
- •Expert’s Comments by Miklosh Bala
- •References
- •13.1 Background
- •13.2 Categorizing Bleeding Severity
- •13.3.1 Emergency IR (EIR)
- •13.5 Trauma IR (TIR)
- •13.5.1 Overview
- •13.5.2 Preadmission
- •13.5.4 Trauma Imaging
- •13.5.5 Patient Selection
- •13.6.1 Overview
- •13.6.2 Procedure
- •13.6.2.3 Embolic Agents
- •13.7 Future Trends
- •13.7.1 Hybrid ER Room
- •13.8 Hybrid Trauma Specialist
- •Conclusion
- •References
- •14.1 Introduction
- •14.3 Communication
- •14.4 Crew Resource Management
- •14.5 REBOA Before or After Anesthesia?
- •14.6 Nonarterial Circulatory Access
- •14.9 Analgesia
- •14.10 Hemostatic Resuscitation
- •14.11 Afterload Reduction
- •14.12 Monitoring
- •14.13 Electrolyte Management
- •14.14 Balloon Deflation
- •Conclusion
- •References
- •15.2 VV ECMO
- •15.3 VV ECMO Circuit Management
- •15.3.1 VV ECMO Cannulation Strategies
- •15.3.2 Monitoring Targets
- •15.4 VV ECMO Patient Management
- •15.4.1 Anticoagulation Range
- •15.4.2 Ventilator Management
- •15.4.3 Sedation Strategies
- •15.4.4 Peri-procedural Management
- •15.5 VA ECMO
- •Conclusions
- •References
- •16.1 Introduction
- •16.4 Access-Related Complications
- •16.6 Fluid Resuscitation
- •16.8 Extracorporeal Membrane Oxygenation
- •16.9 Coagulation
- •16.11 Renal Function
- •Conclusions
- •Expert’s Comments by Andrew Kirkpatrick
- •References
- •17.1 Access Site Complications
- •17.1.1 Hematoma
- •17.1.2 Pseudoaneurysm
- •17.1.3 Acquired Arteriovenous Fistula
- •17.2 Intervention Complications
- •17.2.1 Dissection
- •17.2.2 Thrombosis/Embolization
- •17.2.3 Rupture
- •17.3 Post-procedure Complications
- •17.3.1 Infection
- •17.3.2 Contrast-Induced Nephropathy
- •17.3.3 Contrast Media Allergy
- •Conclusion
- •References
- •18.6.1 Simulators
- •18.6.2 Porcine Models
- •18.6.3 Cadaver
- •18.6.4 Cath-Lab Training
- •18.7 Summary
- •References

xii
Pan American EVTM (#panamevtm2018, Houston, Texas) and EVTM-Ӧrebro in
June 2018 continued the dynamic, interactive discussions and debates with leaders
and interested professionals in this evolving eld internationally.
The intent of this textbook is to provide a comprehensive review of endovascular,
catheter-based approaches and technologies applied in the management of the criti-
cally injured patient and a complete review of damage control resuscitation con-
cepts, strategies, and techniques. This textbook has incorporated the most up-to-date
preclinical and clinical research into today’s evidence-based (i.e., best practice)
approach to trauma management for each chapter. The chapter authors were encour-
aged to highlight advanced endovascular applications for modern resuscitation and
surgical management. We asked the leading experts in trauma, in cooperation with
the World Society of Emergency Surgery (WSES), to add expert’s comments on
selected chapters. Our aim is to meticulously explore important issues, complexi-
ties, and controversies within the developing, cross-disciplinary, international con-
cepts central to EVTM, in order to improve the care and outcomes of the severely
injured patient globally.
Örebro, Örebro Län, Sweden TalHörer
Bethesda, USA ToddE.Rasmussen
Baltimore, USA JoeJ.DuBose
Bethesda, USA JosephM.White
Preface

xiii
Acknowledgments
We would like to recognize our distinguished chapter authors and coauthors who
comprise an international, multidisciplinary cohort of expert clinicians, surgeons,
and scientists. We greatly appreciate their dedication and contribution to this impor-
tant effort regarding endovascular resuscitation and trauma management (#EVTM).
Additionally, we would like to recognize the World Society of Emergency
Surgery (WSES). Their support for this project has been instrumental to its develop-
ment and success.

xv
About the Book
This text, constructed under the leadership of Tal Hörer and colleagues, provides
modern practitioners with insight into the effective incorporation of techniques of
endovascular resuscitation and trauma management (EVTM) into modern medical
care. The eld of EVTM continues to evolve, bringing together an increasingly
larger and more diverse multidisciplinary group of providers interested in exploring
these principles for the betterment of the patients we care for. The authors have
incorporated both current science and experienced practice into each of the described
elements of EVTM practices. As the rst text of its kind, this work is a testament to
the power of innovative collaboration and the diligent pursuit of knowledge as it
pertains to dene the optimal role of EVTM.

xvii
Contents
1 The Concept of Endovascular Resuscitation and Trauma
Management: Building the EVTM Team . . . . . . . . . . . . . . . . . . . . . . . . 1
Tal Hörer, David T. McGreevy, and Rigo Hoencamp
2 Principles of Modern Trauma Resuscitation . . . . . . . . . . . . . . . . . . . . . 13
Rowan R. Sheldon and Matthew J. Martin
3 Endovascular Management of Cervical Vascular Trauma . . . . . . . . . . 35
Todd Simon and Kevin Brown
4 Endovascular Management of Thoracic and Abdominal Trauma . . . . 49
Ravi R. Rajani and Christopher Ramos
5 Endovascular Surgery for Extremity Trauma . . . . . . . . . . . . . . . . . . . . 67
Paul W. White and Erin Koelling
6 Principles of REBOA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Anna Romagnoli and Megan Brenner
7 Partial REBOA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
Anders J. Davidson and Timothy K. Williams
8 REBOA in Traumatic Brain Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Carl A. Beyer and M. Austin Johnson
9 REBOA-Induced Ischemia-Reperfusion Injury . . . . . . . . . . . . . . . . . . 121
Jigarkumar A. Patel and Joseph M. White
10 REBOA in Nontraumatic Cardiac Arrest . . . . . . . . . . . . . . . . . . . . . . . . 135
James Daley and Jonathan Morrison
11 Endovascular Balloon Occlusion in Obstetrical Hemorrhage . . . . . . . 149
Karin A. Fox
12 Prehospital and Austere EVTM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167
Viktor A. Reva
13 Endovascular Embolization in Trauma and Bleeding . . . . . . . . . . . . . . 187
Brandon Dean Lohman and Junichi Matsumoto

xviii
14 Management of the Unstable Patient During EVTM
and REBOA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205
Albert Pierce and Jan O. Jansen
15 Extracorporeal Membrane Oxygenation
in the Unstable Trauma Patient . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215
Emily J. MacKay and Jeremy W. Cannon
16 Postoperative Critical Care Management Considerations . . . . . . . . . . 229
Kristofer F. Nilsson and Birger Axelsson
17 Complications of Endovascular and Hybrid Surgery . . . . . . . . . . . . . . 243
Jeniann Yi and Charles J. Fox
18 Endovascular Resuscitation and Trauma Management:
Education and Simulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253
Yosuke Matsumura, Mikkel Taudorf, Edmund Søvik, and Lars Lönn
Contents

xix
Contributors
Authors
BirgerAxelsson, MD, PhD Department of Cardiothoracic and Vascular Surgery,
Faculty of Medicine and Health, Örebro University Hospital and University, Örebro,
Sweden
Carl A. Beyer, MD Department of Surgery, University of California Medical
Center, Sacramento, CA, USA
Megan Brenner, MD, MS, FACS University of California Riverside School of
Medicine, Riverside, CA, USA
KevinBrown, MD Division of Vascular Surgery, Walter Reed National Military
Medical Center, Bethesda, MD, USA
JeremyW. Cannon, MD Division of Traumatology, Surgical Critical Care and
Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania,
Philadelphia, PA, USA
Department of Surgery, F.Edward Hébert School of Medicine, Uniformed Services
University of the Health Sciences, Bethesda, MD, USA
JamesDaley, MD, MPH, MS
Section of Emergency Ultrasound, Department of
Emergency Medicine, Yale New Haven Hospital, New Haven, CT, USA
AndersJ.Davidson, MD, MAS Department of Surgery, University of California
Davis Medical Center, Sacramento, CA, USA
Charles J. Fox, MD, FACS Division of Vascular Surgery and Endovascular
Therapy, Department of Surgery, University of Colorado Anschutz Medical Campus,
Aurora, CO, USA
Denver Health Medical Center, University of Colorado School of Medicine, Denver,
CO, USA
Karin A. Fox, MD, MEd, FACOG Maternal-Fetal Medicine, Department of
OB-GYN, Baylor College of Medicine, Houston, TX, USA
Medical Director of Maternal Transport, Texas Children’s Hospital Pavilion for
Women, Houston, TX, USA

xx
RigoHoencamp, MD, PhD, FEVBS Leiden University Medical Centre, Leiden,
The Netherlands
Department of Surgery, Alrijne Hospital, Leiderdorp, The Netherlands
Defense Healthcare Organization, Ministry of Defense, Utrecht, The Netherlands
Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical
Center Rotterdam, Rotterdam, The Netherlands
TalHörer, MD, PhD
Department of Cardiothoracic and Vascular Surgery, Örebro
University Hospital, Örebro, Sweden
Department of Surgery, Örebro University Hospital, Örebro, Sweden
JanO. Jansen, MBBS, PhD, FRCS, FFICM Division of Acute Care Surgery,
University of Alabama at Birmingham, Birmingham, AL, USA
M. Austin Johnson, MD, PhD Department of Surgery, Univeristy of Utah,
SaltLake City, UT, USA
Brandon Dean Lohman, MD Division of Trauma and Emergency Radiology,
Department of Emergency and Critical Care Medicine, St. Marianna University
School of Medicine, Kawasaki City, Kanagawa Prefecture, Japan
LarsLönn, MD, PhD Department of Cardiovascular Radiology, Faculty of Health
Sciences, National Hospital, University of Copenhagen, Copenhagen, Denmark
Emily J. MacKay, DO MD Department of Anesthesiology and Critical Care,
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA,
USA
MatthewJ.Martin, MD, FACS Trauma and Emergency Surgery Service, Scripps
Mercy Hospital, San Diego, CA, USA
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Junichi Matsumoto, MD Division of Emergency and Trauma Radiology,
Department of Emergency and Critical Care Medicine, St Marianna University
School of Medicine, Kawasaki, Kanagawa, Japan
YosukeMatsumura, MD Department of Emergency and Critical Care Medicine,
Chiba University Graduate School of Medicine, Chiba, Japan
David T.McGreevy, MD Department of Cardiothoracic and Vascular Surgery,
Örebro University Hospital, Örebro University, Örebro, Sweden
Erin Koelling, MD, FACS, CDR(sel), MC, USN The Department of Surgery,
Walter Reed National Military Medical Center, Uniformed Services University of
the Health Sciences, Bethesda, MD, USA
Jonathan Morrison, MB, ChB, MRCS, PhD Division of Vascular Surgery,
Department of Surgery, The University of Maryland Medical School, Baltimore,
MD, USA
Contributors

xxi
Kristofer F. Nilsson, MD, PhD Department of Cardiothoracic and Vascular
Surgery, Faculty of Medicine and Health, Örebro University Hospital and University,
Örebro, Sweden
JigarkumarA.Patel, MD, MAJ, MC, USA The Department of Surgery, Walter
Reed National Military Medical Center, Uniformed Services University of the
Health Sciences, Bethesda, MD, USA
Albert Pierce, MD Department of Anesthesiology and Perioperative Medicine,
University of Alabama at Birmingham, Birmingham, AL, USA
Ravi R. Rajani, MD, FACS Division of Vascular and Endovascular Surgery,
Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA
Christopher Ramos, MD Division of Vascular and Endovascular Surgery,
Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA
ViktorA. Reva, MD, PhD Department of War Surgery, Kirov Military Medical
Academy, Saint-Petersburg, Russian Federation
AnnaRomagnoli, MD, MAJ, MC, USA Department of Surgical Critical Care,
RA Cowley Shock Trauma Center, University of Maryland Medical Center,
Baltimore, MD, USA
RowanR.Sheldon, MD, CPT, USA, MC Department of Surgery, Madigan Army
Medical Center, Tacoma, WA, USA
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
ToddSimon, DO, FACS, LTC, MC, USA Division of Vascular Surgery, Dwight
D. Eisenhower Army Medical Center, Fort Gordon, GA, USA
Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Edmund Søvik, MD Department of Radiology, St. Olav’s University Hospital,
Trondheim, Norway
Medical Simulation Center, St. Olav’s University Hospital, Trondheim, Norway
MikkelTaudorf, MD, PhD
Department of Cardiovascular Radiology, Copenhagen
Academy for Medical Education and Simulation (CAMES), Rigshospitalet,
Copenhagen, Denmark
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
JosephM.White, MD, FACS, MAJ(P), MC, USA The Department of Surgery,
Walter Reed National Military Medical Center, Uniformed Services University of
the Health Sciences, Bethesda, MD, USA
PaulW.White, MD, FACS, FSVS, COL, MC, USA The Department of Surgery,
Walter Reed National Military Medical Center, Uniformed Services University of
the Health Sciences, Bethesda, MD, USA
Contributors

xxii
Timothy K. Williams, MD Vascular and Endovascular Surgery, Wake Forest
Baptist Health, Winston-Salem, NC, USA
Jeniann Yi, MD, MS Division of Vascular Surgery and Endovascular Therapy,
Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora,
CO, USA
Experts
Luca Ansaloni, MD General, Emergency and Trauma Department, Bufalini
Hospital, Cesena, Italy
Catherine Arvieux Trauma Centre Grenoble-Alpes, Chuga-University Hospital
Grenoble Alpes UGA-Grenoble Alpes University, Saint-Martin-d’Hères, France
Miklosh Bala, MD Hadassah—Hebrew University Medical Center, Jerusalem,
Israel
FaustoCatena, MD, PhD General and Emergency Surgery Department, Parma
University Hospital, Parma, Italy
AlessandroCircelli, MD ICU Department, Bufalini Hospital, Cesena, Italy
FedericoCoccolini, MD General, Emergency and Trauma Department, Bufalini
Hospital, Cesena, Italy
Emiliano Gamberini, MD Anesthesia and Intensive Care Department, Major
Trauma Center, Bufalin Hospital, Cesena, Italy
AndrewKirkpatrick, MD Foothills Medical Centre, Calgary, AB, Canada
Canadian Forces Medical Services, Borden, Canada
YoramKluger, MD, FACS, FISA Rambam Health Care Center, Haifa, Israel
ErnestE.Moore, MD University of Colorado Denver, Denver, CO, USA
Ernest E Moore Shock Trauma Center at Denver Health, Denver, CO, USA
Edoardo Picetti, MD Department of Anesthesia and Intensive Care, Parma
University Hospital, Parma, Italy
Editors
TalHörer, MD, PhD Department of Cardiothoracic and Vascular Surgery, Örebro
University Hospital, Örebro, Sweden
Department of Surgery, Örebro University Hospital, Örebro, Sweden
Contributors

xxiii
JosephM.White, MD, FACS, MAJ(P), MC, USA The Department of Surgery at
Uniformed Services, University of the Health Sciences and Walter Reed National
Military Medical Center, Bethesda, Maryland, USA
Joe J. DuBose, MD, FACS, FCCM University of Maryland Medical Center,
RAdams Cowley Shock Trauma Center, Baltimore, Maryland, USA
Todd E. Rasmussen, MD FACS F. Edward Hebert School of Medicine –
“America’s Medical School”, Uniformed Services University of the Health Sciences,
Bethesda, Maryland, USA
Walter Reed National Military Medical Center, The National Institutes of Health
Clinical Center, Bethesda, Maryland, USA
Contributors
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