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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5632_Библиотеки_им_академика_М_И_Перельмана.pdf
X
- •Foreword
- •Preface
- •About the Book
- •Contents
- •1.2.3 Ceramic Biomaterials
- •1.2.4 Composite Biomaterials
- •1.2.5 Nanocellulose
- •1.3.1 Biocompatible Proteins
- •1: Sustainable Green Biomaterials in Drug Delivery
- •1.1 Introduction
- •1.2 Classification
- •1.2.1 Metallic Biomaterials
- •1.2.2 Polymeric Biomaterials
- •1.3.2 Composites (Cellulose, Chitosan, and Chitin)
- •1.3.3 Hydroxyapatite-Starch Based Biomaterials
- •1.3.4 Carbonaceous Materials
- •1.4 Perspective
- •1.4.1 Current Recycling Strategies
- •1.4.2 Dental and Orthopedic Implants
- •1.4.3 Medical Plastic Waste
- •1.4.4 Sterilization and Reusability
- •1.4.5 Waste Management for Recycling
- •1.5 Conclusion and Future Challenges
- •References
- •2: Prospects of Biodegradable Material: Sustainable and Patient-Centric Approach in the Realm of Biomedical Engineering
- •2.1 Introduction
- •2.2 Sustainable Green Biomaterials
- •2.2.1 Naturally Derived Polymers and Polymer Substrates
- •2.2.1.1 Protein Based Sustainable Biomaterials
- •2.2.1.2 Polysaccharides Based Sustainable Biomaterials
- •2.2.1.3 Hydroxyapatite Based Sustainable Biomaterials
- •2.2.1.4 Carbonaceous Sustainable Biomaterials
- •2.2.2 Synthetic Polymer Substrate
- •2.2.3 Biodegradable Metal Substrates
- •2.4 Bio-degradable Piezoelectrics for Medical Implants
- •2.5.1 Wound Healing
- •2.5.2 Drug Delivery Systems
- •2.5.2.1 Nano-based Drug Delivery Systems
- •2.5.2.2 Polymeric Nanoparticles
- •2.5.2.3 Solid-Lipid Nanoparticles (SLNs)
- •2.5.2.4 Liposomes
- •2.5.3 Medical Devices
- •2.5.3.1 Implants
- •2.5.3.2 Other Applications
- •2.7 Prospects and Conclusion
- •References
- •3: Strategies in Synthesis of Biodegradable Polymers
- •3.1 Introduction
- •3.2 Natural Biopolymers
- •3.2.1 Polysaccharides
- •3.2.2 Polynucleotide
- •3.2.3 Polypeptides
- •3.3 Chemically Synthesized Biodegradable Polymers
- •3.3.1 Extraction Methods of Biodegradable Polymers
- •3.3.2 Polymerization of Biodegradable Polymers
- •3.3.3 Fermentation Method of Biodegradable Polymers
- •3.3.4 Sonosynthesis of Biodegradable Polymers
- •3.3.5 Solvent Casting Method of Biodegradable Polymers
- •3.3.6 Electrospinning Method
- •References
- •4: Probiotic Bacterial Cellulose: A Bio-mediated Nanomaterial for Health Care Applications
- •4.1 Introduction
- •4.2 Probiotic Bacterial Cellulose and Bacterial Cellulose
- •4.3 Producers of Bacterial Cellulose
- •4.3.1 Process of Bacterial Cellulose Synthesis
- •4.4 Probiotic Bacteria and Their Beneficial Effects
- •4.5 Methods of Synthesizing Probiotic Bacterial Cellulose
- •4.6 Healthcare Applications of Probiotic Bacterial Cellulose
- •4.7 Conclusion
- •References
- •5: 3D Printing and 4D Printing: Sustainable Manufacturing Techniques for Green Biomaterials
- •5.1 Introduction
- •5.2 Fundamentals of 3D and 4D Bioprinting
- •5.3 Biomaterials in 3D Bioprinting
- •5.3.1 Types of Polymers Used in 3D Bioprinting (Fig. 5.1)
- •5.3.1.1 Synthetic Polymers
- •Polylactic Acid (PLA)
- •Polyethylene Glycol (PEG)
- •5.4 Polyglycolic Acid (PGA)
- •5.5 Sustainability in 3D Printing
- •5.5.1 What Makes your Biomaterial more Sustainable?
- •5.6 Advancements in 4D Bioprinting
- •5.6.1 Smart Polymers
- •5.6.2 Applications of 4D Bio-Printing in Sustainable Manufacturing
- •5.7 Case Studies on 3D and 4D Bioprinting
- •5.8 Challenges and Future Directions in 3D and 4D Bioprinting
- •5.8.1 The Technical Challenges in 3D Bio-Printing Include
- •5.8.2 Challenges in 4D Bio-Printing
- •5.8.3 Future Directions
- •5.9 Conclusion
- •References
- •6: Proteins as Biocompatible Material for Biomedical Applications
- •6.2.6 Zein
- •6.3 Proteins as Adaptable and Biocompatible Building Blocks for Biomedical Applications in Biomaterials
- •6.4.1 Protein-Based Particle Systems
- •6.1 Introduction
- •6.2 Protein Materials
- •6.2.1 Keratin
- •6.2.2 Collagen
- •6.2.3 Elastin
- •6.2.4 Silk
- •6.2.5 Resilin
- •6.4.2 Protein-Based Hydrogels
- •6.4.3 Protein-Based Films
- •6.4.4 Protein Electrospun Fibers
- •6.4.5 Protein-Based Microneedles
- •6.4.6 Keratin Composites
- •6.4.7 Elastin Composites
- •6.4.8 Collagen Composites
- •6.5.1 Bone Healing
- •6.5.2 Antibiotic Release
- •6.5.3 Diabetes
- •6.5.4 Cancer Treatment
- •6.5.5 Neuroinflammation
- •6.5.6 Wound Healing
- •6.5.7 Corneal Regeneration
- •6.6 Conclusion
- •References
- •7: Graphene-Based Carbonaceous Materials: A Sustainable Biomaterial for Biomedical Application
- •7.1 Introduction
- •7.2 Graphene and Its Family
- •7.2.1 Structure of Graphene
- •7.2.2 Properties of Graphene-Based Biomaterials
- •7.2.3 Synthesis of Graphene Compounds
- •7.2.4 Applications of Graphene Compounds
- •7.3 Carbonaceous Materials in Biomedical Applications
- •7.3.1 Tissue Engineering
- •7.3.2 Biosensing
- •7.3.3 Drug Delivery
- •7.3.4 Smart Biomaterials
- •7.4 Biomaterials and Sustainability
- •7.4.1 Sustainability in Graphene-Based Materials
- •References
- •8: Green Approach for Synthesizing Silk Fibroin Biomaterial Scaffolds
- •8.1 Introduction
- •8.3.1 Green Alternatives for Degumming
- •8.3.2 Green Alternative to Dissolution Techniques
- •8.3.3 Green Alternative to Fabrication Techniques
- •8.5 Applications of Silk Fibroin Biomaterial Scaffolds
- •8.6 Conclusion
- •References
- •9: Green Catalysts in the Synthesis of Biomaterials for Biomedical Applications
- •9.1 Introduction
- •9.2 Green Catalyst and Its Classification
- •9.2.1 Green Catalyst from the Light Source
- •9.2.2 Green Catalyst from Bio Source
- •9.2.3 Green Catalyst from Nanotechnology
- •9.2.4 Green Catalyst from Heteropolyacids
- •9.3 Biomedical Applications
- •9.3.1 Drug Delivery
- •9.3.2 Polymer Coating
- •9.3.3 Biosensor
- •9.3.4 Tissue Engineering
- •9.3.5 Wound Healing
- •9.3.6 Bioprinting
- •9.4 Methods Involved in the Synthesis of Green Catalyst
- •9.4.1 Green Solvent Synthesis Method of Catalyst
- •9.4.2 Biosynthesis Method of Catalyst
- •9.4.3 Electrochemical Synthesis Method of Catalyst
- •9.4.4 Plasma Method
- •9.4.5 Ultrasonic-Aided Synthesis
- •9.4.6 Microwave-Aided Synthesis (MAS)
- •9.4.7 Alternative Green Methods
- •9.5 Conclusion
- •References
- •10: Utilisation of Plant Extracts for Green Synthesis of Metallic Nanoparticles
- •10.1 Introduction
- •10.1.1 Silver Oxide Nanoparticles
- •10.1.2 Synthesis of Gold Nanoparticles
- •10.1.3 Synthesis Iron Oxide Nanoparticles
- •10.1.4 Cerium Oxide Nanoparticles
- •10.1.5 Zinc Oxide Nanoparticle
- •10.1.6 Copper Oxide Nanoparticle
- •10.1.7 Palladium Nanoparticles
- •10.2 Conclusion
- •References
- •11.1 Introduction
- •11.3 Sustainable Synthesis of Metal Nanoparticles Using Waste
- •11.3.1 Agri-Wastes
- •11.3.2 E-Wastes
- •11.3.3 Industrial-Wastes
- •11.5 Conclusion
- •References
- •12: Metal Framework in Biosensor
- •12.1 Introduction
- •12.2 Synthesis of MOFs
- •12.3 Sensors
- •12.3.1 Various Types of Biosensors
- •12.3.1.1 Electrochemical Biosensors
- •12.3.1.2 Amperometric and Voltammetric Immunosensor
- •12.3.1.3 Electrochemiluminescence (ECL) Biosensor
- •12.3.1.4 Aptamers
- •12.3.1.5 Field-Effect-Transistor-Based Sensors (FET)
- •12.3.1.6 MOF-Nanomaterials-Based Biosensors
- •12.3.1.7 Food Quality Monitoring
- •12.3.1.8 Environmental Analysis
- •12.3.1.9 Pesticide
- •12.3.1.10 Gas Sensors
- •12.3.1.11 Temperature Sensor
- •12.4 Diagnosis of Diseases
- •12.4.1 Cancer
- •12.4.2 Glucose Sensor
- •12.4.4 HIV Sensor
- •12.4.5 MOF Used for Optical Sensors
- •12.5 Conclusion and Future Perspective
- •References
- •13: Cellulose, Chitin, and Chitosan Composite-Based Sustainable Biomaterials
- •13.1 Introduction
- •13.2 General Structures of Cellulose, Chitin and Chitosan
- •13.2.1 Cellulose
- •13.2.2 Chitin
- •13.2.3 Chitosan
- •13.3.1 Cellulose Composite-Based Biomaterials
- •13.3.2 Chitin-Chitosan Composite-Based Biomaterials
- •13.5 Advantages and Disadvantages
- •13.7 Conclusion
- •References
- •14: Sustainable Synthesis of Cellulose-Derived Hydrogels for Tissue Engineering
- •14.1 Introduction
- •14.1.1 Overview of Cellulose-Derived Hydrogels
- •14.1.3 The Aim of this Chapter
- •14.2 The Sustainable Biomaterial of Cellulose
- •14.2.1 Cellulose Structure and Properties
- •14.2.2 Properties of Cellulose
- •14.2.3 Sources of Cellulose for Hydrogel Synthesis
- •14.2.4 Advantages of Using Cellulose-Derived Materials
- •14.3 Cellulose Hydrogel Formation Techniques
- •14.3.1 Synthesis Methods
- •14.3.1.1 Chemical Crosslinking Methods
- •14.3.1.2 Physical Crosslinking Methods
- •14.3.1.3 Hybrid Approaches
- •14.4 Tissue Engineering Applications
- •14.4.1 Scaffold Design Considerations
- •14.4.2 The Biocompatibility of Cellulose-Based Hydrogels
- •14.4.3 Case Studies of Tissue Engineering with Hydrogels Generated from Cellulose
- •14.5 Sustainability in Cellulose Hydrogel Synthesis
- •14.5.1 Green Synthesis Approaches
- •14.5.3 Assessment of the Life Cycle of Hydrogels Generated from Cellulose
- •14.6 Characterization Techniques
- •14.6.1 Structural Analysis
- •14.6.2 Mechanical Properties
- •14.6.3 Biodegradability Studies
- •14.7 Challenges and Future Directions
- •14.7.1 Current Limitations in Cellulose-Based Hydrogel Technology
- •14.7.2 Opportunities for Further Research and Development
- •14.8 Conclusion
- •14.8.1 Summary of Key Points
- •14.8.2 Implications for the Field of Tissue Engineering
- •14.8.3 Recommendations for Future Work
- •References
- •15: Hydroxyapatite-Starch-Based Sustainable Biomaterials
- •15.1 Introduction
- •15.2 Hydroxyapatite
- •15.2.1 Biomedical Applications of Hydroxyapatite
- •15.3 Starch
- •15.3.1 Sources, Structure and Properties of Starch
- •15.3.2 Biomedical Applications of Starch
- •15.5 Synthesis Techniques for HA-Starch Composites
- •15.5.1 Electrospinning
- •15.5.2 Sol-Gel
- •15.5.3 Thermally Induced Phase Separation
- •15.6 Starch-Based Drug Delivery Systems
- •15.8 Hydroxyapatite-Starch Based Drug Delivery Systems
- •15.10 Future Perspectives and Challenges
- •15.11 Conclusion
- •References
- •16: Surfactant-Free Synthesis of Metal and Metal Oxide Nanomaterials: Sustainable and Eco-Synthesis Methods
- •16.1 Introduction
- •16.2.1 Solvent-Assisted Synthesis
- •16.2.1.1 N,N-Dimethylformamide (DMF) Assisted Synthesis
- •16.2.1.2 Ethylene Glycol Assisted Synthesis
- •16.2.1.3 Benzyl Alcohol Assisted Synthesis
- •16.2.1.4 Methyl Isobutyl Ketone Assisted Synthesis
- •16.2.2 Simple Ion Assisted Synthesis
- •16.2.2.1 Citrate Assisted Synthesis
- •16.2.2.2 Amino Acid Assisted Synthesis
- •16.2.2.3 Iodide Assisted Synthesis
- •16.2.2.4 Buffer Assisted Synthesis
- •16.2.3 Physical Process-Mediated Synthesis
- •16.2.3.1 Photochemically-Mediated Synthesis
- •16.2.3.2 Sonochemically Assisted Synthesis
- •16.2.3.3 Laser Ablation-Mediated Synthesis
- •16.3.1 Synthetic Catalysis
- •16.3.2 Electrocatalysis
- •16.3.3 Surface-Enhanced Raman Scattering
- •16.4 Challenges, Limitation, and Future Perspective
- •16.5 Conclusions
- •References
- •Index

16 Surfactant-Free Synthesis of Metal and Metal Oxide Nanomateria ls:… 427
Ushasi Das Presently a PhD Research Scholar in the Department
of Pharmaceutical Technology at Jadavpur University, Kolkata.
Her academic journey commenced with an undergraduate degree
in Pharmacy from NSHM College of Pharmaceutical Technology,
NSHM knowledge campus, Kolkata in 2011, followed by postgraduate studies M. Pharm in Pharmaceutics at NSHM College of
Pharmaceutical Technology, NSHM knowledge campus, affiliated
to West Bengal University of Technology, culminating in 2013.
Over the past 10 years, she has made signi ficant contributions to
various institutions as an Analytical Chemist, including Joy
Beauty Care Pvt. Ltd. and Central Drugs Laboratory, Kolkata.
She has authored over 14 research and review articles, edited two
books, and six book chapters.
Dr. Popat Mohite is currently
working as an Associate professor
and Head of the Department at St. John Institute of Pharmacy and
Research, Palghar. He has a total of 16 years’ experience in
teaching. He has several National and International Journals
publications to his credit and Research grants from the University
of Pune. He has presented research papers at several national and
international conferences. He has guided more than 35 PG
students. He has published 85 research and review articles in
various national and international journals of repute. He has
authored 03 books in Lambert publishing house. He has granted
01 and published 01 patents. He is a reviewer and member of the
editorial board of various journals. He is a lifetime member of
IPA, APTI and ISTE. He was awarded with Young Researcher
Award, Young Scientist and Young Faculty award. His research
areas are synthesis and biological evaluation, QSAR study formulation, surface functionalization of polymers and analytical
method development and validation. His current Google Scholar
h-Index is 18; i10-Index is 28 with citation of 1075.
Dr. Sanchita Mandal is currently working as an assistant professor in the Department of Pharm Tech. at Jadavpur University.
She had qualified in GATE 2004, was Awarded UGC JRF in 2007
and the CSIR SRF (senior research fellowship) in 2010. She was
awarded her PhD from Jadavpur University in 2012. She attended
two oral presentations in Thailand and NTU Singapore. Stood 2nd
in the International Workshop-Seminar on ‘Liposome: From The-
ory to Practice’ 2010. She has also been an Approved Mumbai
University faculty member since 2012 and has worked at various
colleges in Mumbai. Recently, she has published four books
between 2021 and 24 and many Book Chapters. She also
published an AU Patent, in December 2021, Australian Government IP Australia. She has joined Jadavpur University in 2021.
She is also guiding four M. Pharm Student and three PhD students
and working with silicone nanoparticles, combating anti-microbial
resistance with hybrid nanogel, graphene and metal nano
composites, novel wound healing enzymes. So far she has gained
total experience of 18 years including Research and Teaching.

428 S. Churi et al.
Dr. Sudarshan Singh presently working as a Frontier Proactive
Researcher in Chiang Mai University, Thailand. He has authored
several technical books and books chapters and more than two
hundreds of research/review papers in reputed peer-reviewed
journals. He has registered five patents on his credit. He is working
as reviewer of various international journals. He has eleven years
of teaching experience in undergraduate and postgraduate courses
of pharmacy with more than six years of postdoctoral research
experience. He has guided several undergraduate and postgraduate
students in their project work. Moreover, during his postdoctoral
research at Prince of Songkhla University, Walailak University,
and Chiang Mai University, Thailand, co-supervised doctorate
students and won award of top researcher for the year of
2020–2021. He is a life member of professional bodies such as
the Society of Pharmacovigilance India and a registered pharmacist at the State Pharmacy Council of Chhattisgarh, India.

Index
A
Agri-wastes, 278–279, 289
α-amino acids (α-AA), 409
Anhydroglucose unit (AGU), 319
Anti-analgesic activity, 266
Antibacterial, 256–258, 262–266
Anti-cancer, 87, 93
Anti-cancer property, 260
Anti-inflammatory, 257, 266
Antimicrobial, 82, 85, 87, 88, 90, 92, 95, 256–
259, 261–264, 266
Antimicrobial activity, 278, 279
Antiviral, 256
Apple juice, 82
Applications, 132–154
Arthroplasty, 5
Artificial skin, 5
Au nanoparticles (AuNPs), 403, 408–412, 415,
416, 418
AuCl
-ions, 409
4
B
Bacillus subtilis, 286, 287
Bacterial cellulose, 76–96
Bacteriocins, 80, 86, 88, 89
Benzyl alcohol (B
OH), 405, 406, 417, 418
Z
B-1,4-glucosidic linkages, 320
Bile salt hydrolases (BSH), 88
Bioactive, 133, 145
Bioceramics, 4
Biocompatibility, 77, 80, 82, 83, 91, 95, 96,
166, 167, 174, 176–178, 182, 183, 262,
265, 333, 334
Biocompatible, 132–154
Biodegradability, 80, 91, 96, 167, 176, 183,
375, 380, 389
Biodegradable, 3–5, 7–11, 16,
133, 137, 140,
141, 146, 148, 154
Biodegradable proteins, 141
Bioengineering, 135, 136, 139–141, 148, 149
Biological activity, 59, 71
Biomaterials, 133, 134, 136–138, 140–150,
154, 219–243, 318
Biomedical,
26–49, 132–154
–335, 374–391
Biomedical application, 219–243
Biomimetic, 174, 178
Biomolecular proteins, 133
Biomonitoring technology, 296
Biopolymers, 29, 35, 41, 42, 46, 47, 138, 148,
150
Bioprinting, 220, 228, 236, 242
Biosensing, 175, 179
–180, 182
Biosensor applications, 297
Biosensors, 220,
223, 229, 230, 242
Biotechnology, 139
Black phosphorous, 220
C
Calcium ions (Ca
2+
), 352, 353
Capping agents, 403, 408, 412, 413, 419
Carbonaceous, 12, 166–187
Carbon-based nanomaterials, 296
Carbon dots, 167, 174, 181
Carbon nanotubes (CNTs), 167, 174, 177, 178,
296, 301, 302
Carboxymethyl cellulose (CMC), 349, 356
Catalytic c-MOF, 302
Cell adhesion, 174, 175, 177, 178
Cell proliferation, 176, 177
Cellulose, 318–335
Cellulose n
Ceramics, 4–6,
anocrystals (
11, 14, 16
CNCs), 349
#
The Editor(s) (if applicable)
and The
Author(s), under exclusive license to
Springer Nature Switzerland AG 2025
R. Malviya, S. Sundram (eds.), Sustainable Green Biomaterials As Drug Delivery
Systems, Biomaterials, Bioengineering and Sustainability 1,
https://doi.org/10.1007/978-3-031-79062-1
429

430 Index
Cerium oxide nanoparticle, 262
Chemistry, 375, 386
Chitin, 318–335
Chitosan, 29–32, 39, 40, 42, 43, 46, 318–335
Citrate assisted synthesis, 407–408
Citric acid, 201, 208
c-MOF-gated FET biosensors, 302
Coating agents, 281, 287, 289
Cobalt (II) chloride hexahydrate, 413
Co-culture, 90, 91
Collagens, 7–9
Composite materials, 318–335
Composites, 375, 377–379, 381–385, 388, 390,
391
Compression moulding, 324–326
Concentrations detection (nM), 302, 309
Condensation dehydration processes, 59
Conductive polymers, 178
Controlled release, 377, 378, 384, 385, 387
Copper oxide nanoparticle, 264, 265
Crude drugs, 276–289
D
Deep Eutectic Solvent (DES), 200, 202, 203,
208
Degradation kinetics, 323,
324
Degumming, 200–204, 208
DNA,
60, 61
Drug delivery, 2–16, 27, 28, 30–35, 37, 39, 42,
44–46, 48, 49, 77, 78, 80, 91–93, 96,
132, 133, 135, 136, 138, 139, 145,
148–154, 220, 222, 223, 227, 228, 242,
327, 330, 332, 374, 375, 377
–382,
384–391
Drug,
375, 377, 378, 381, 384– 391
Dynamic light scattering (DLS), 284, 285
E
Eco friendly, 264
EDS, 285, 286
Electrical
signals, 300, 302
Electrocatalysis, 403, 414, 416–417
Electrochemical amplification, 302
Electrochemical sensors, 298, 300, 304, 307
Electrohydrodynamic, 8
Electrospinning, 377, 381–382
Electrospinning method, 69–71
Enhancement factor (EF), 417, 418
Environmentally friendly products, 60
Environmental remediation, 261, 262, 265
Enzymatic degumming, 200–203, 208
Escherichia coli, 280, 286, 287
Ethylene glycol (EG), 401, 404–405, 414, 416,
418
E-wastes, 278–280
Exopolysaccharides (EPS), 87–89
Extraction methods of biodegradable polymers,
–64
62
Extracts, 276–289
F
Fermentation, 76, 78, 79, 81–84, 86, 96
Fermentation method of biodegradable
polymers, 65–66
Field-effect transistors (FETs), 298, 302
4D printing, 27, 35–37
Fourier transform infrared spectroscopy (FTIR),
360, 361
Functional groups, 169–171, 173, 179, 181,
182
G
Gas sensor
(SO
), 302, 305
2
Gelatin methacryloyl (GelMA), 352, 353
Gelatins, 7–11
Genetic engineering, 139
Gold nanoparticles (AuNPs), 408–411, 415
Graphene, 167–174, 176–182, 184–186, 220,
224, 229–232, 234, 238, 296, 302, 309
Graphitization, 167, 185
Green biomaterials, 104, 105, 110–112, 116
Green catalysts, 219, 220, 226, 227, 229, 230,
237, 239, 242
Green chemistry, 219, 234, 236
Greener approaches, 200, 203
Green synthesis, 253–265
Gut-brain axis, 88
Gut microbiota, 77, 83, 88
H
Hand lamination, 325
HEPES, 410, 418
Heteropolyacids (HPAs), 220, 226, 227
High mobility, 302
Hummer’s method, 171, 185
Hydrogels, 5, 8, 9, 11, 12, 222, 231–233, 235,
236
Hydroxyapatite, 3
8, 374–379, 381–383,
3, 3
385–391
Hydroxyethyl cellulose
(HEC), 349

Index 431
I
Immunomodulation, 94
Immunosensors, 298–300, 304–307, 309
Implants, 26–28, 34, 36–38, 46–49
Inducing secondary structures, 200, 202
Industrial wastes, 278, 280–281
Injection moulding, 324, 326, 328
Intermetallic nanoparticles (iNPs), 417
Iodide assisted synthesis, 409–410
Iron oxide nanoparticles, 261–262
K
Kampo medicines, 282, 288
Keratins, 7, 8
Komagataeibacter sp., 76, 79, 82, 90, 91, 93
L
Laser ablation, 412
Life cycle assessment (LCA), 358–360, 365
Liposome, 43, 45, 46
Lyophilization, 198, 201, 208
M
Materials, 26–49, 132–154
Maxillofacial implants, 5
Medical, 132, 133, 151, 154
Medical devices, 136
Medicinal plants, 276, 281–289
MEMS processes, 302
Metal and metal oxides,
400–419
Metal-based materials, 308
Metal-organic frameworks (MOFs), 220, 226,
228, 241, 242, 296–298, 300–310
Metal oxides, 296, 309
Metal substrate, 34
Methyl isobutyl ketone (MIBK), 401, 406
Microbial biodegradable
polymers, 66
–407
Microbial synthesis, 322
Microbiological resistance, 136
Microporous ZIF-67 MOFs, 302
MXene, 220, 225,
231
N
Nanocatalyst, 220,
238
Nanocelluloses, 6
Nanocomposites, 173, 176, 180
Nanocrystalline cellulose (NCC), 355
Nanofibers, 77, 81
Nanomaterials, 75–96, 105, 111, 113, 114, 116,
166–168, 174, 177, 181, 220, 221, 226,
228, 229, 231, 241, 242, 259, 265,
276–278, 280, 296, 300, 302, 319, 363,
399–419
Nanomedicine, 374, 375, 378–381, 384, 385,
390, 391
Nanoparticle-based materials, 302
Nanoparticles (NPs), 34, 43, 45, 221–224, 226,
228–230, 232, 237–239, 241, 242,
253–265, 400–405, 407–419
Nara, 276–289
Natural biopolymers, 58–62
Neurotransmitters, 88, 302
Nickel (II) acetate tetrahydrate, 413
N-methylmorpholine 4-oxide (NMMO), 350
N,N-dimethylformamide (DMF), 401–403,
414, 415
Non-toxicity, 236
Nucleic acids, 308, 309
O
Osteogenic differentiation, 176
P
Paeonia lactiflora, 282–289
Palladium nanoparticle, 265, 266
Patient-centered, 26, 34, 36,
49
Pd-nanoclusters, 414
Peony,
282, 283, 289
Personalized medicine, 334
Photocatalysts, 220–222
Photocatalytic properties, 262
Photoredox catalysis,
411
Physico-mechanical attributes, 323
Phytochemi
cals, 253, 254, 260, 262
Piezoelectric, 37–39, 47, 48
Plant derived biomaterials, 104–124
Plant extract, 253–265
Platinum-based nanoparticles, 302
Polyamide, 5
Polyesters, 4, 5, 12
Polyethylene glycol (PEG), 352
Polymer coatings, 220, 242
Polymeric, 43,
Polymerization o
45
f b
iodegradable polymers,
64–65
Polymers, 26–29, 31–37, 39, 41, 43, 44, 46–49,
105, 107–112, 115–116, 119, 120, 124,
377, 379, 381–387, 389, 390

432 Index
Polynucleotides, 59–61
Polypeptides, 59, 61–62
Polyphenols, 277, 279, 281
Polysaccharides, 8, 10, 12, 29, 31, 39, 59–60,
62, 63, 65, 67, 69, 381, 384
Polyvinyl alcohol (PVA), 352, 353
Porosity, 77, 79, 81, 82, 91
Probiotics, 76–96
Protein-based materials, 154
Proteins, 132–154
Pultrusion, 325
Q
Quantum dots (QDs), 296, 303
Quick output signal response, 302
R
Recycle, 14, 15
Reduced graphene oxide (rGO), 304, 416
Reducing agents, 276, 277, 279, 282, 289
Reducing stability, 409
Regenerated silk fibroin (RSF), 199, 205–207
Regenerative medicine, 26, 35–37, 45, 135, 148
Release systems, 334
Renewable, 3, 7, 11, 12
Resilin, 7, 9
Resin transfer, 326
RNA, 60
S
Scaffolds, 26, 28,
30, 33–41, 43–46, 138–141,
146–149, 151, 166, 168, 174–178,
181–183, 185, 223–226, 232
Scanning electron microscopy
(SEM), 285,
286, 360, 361
Self-assembly, 181
Self healing, 176, 181, 182
Semiconducting quantum dots, 302
Sensing devices, 35
Sensor technologies, 296, 299
Sericin, 197, 200, 201, 203, 204, 208
Short-chain fatty acids (SCFAs), 80, 86–89
Silk biodegradability, 197
Silk fibroins, 196–208
Silk I, 197, 199
Silk II, 197, 199
Silk III, 199
Silkworm, 196, 197, 200, 208
Silver ions, 402, 408, 409
Silver nanoparticles, 276–289
Silver oxide nanoparticle, 254–255
Sodium Hydroxide and Urea, 202
Solvent casting method of biodegradable
polymers, 69–70
Sonochemical synthesis, 412
Sonosynthesis of biodegradable polymers,
66–69
Sonosynthesis process, 69
Spider silk, 197
Starch, 374, 375, 379–391
Sterilized silk fibroin, 197
Supercritical CO
fluid, 201
2
Surface-enhanced Raman scattering, 417–418
Surface plasmon resonance (SPR), 284
Surfactant-free synthesis, 400–419
Sustainability, 168, 182–186, 242, 243, 375,
384, 385
Sustainable, 26–49
Sustainable green, 2–16
Sutures, 5
Synthetic catalysis, 414–416
Synthetic polymer, 318, 323, 334
T
Therapeutics, 3, 15, 16, 132–134, 142, 146,
149, 150, 154
Thermogravimetry
3-dimension
(TG), 285, 287, 288
(3D), 27,
32, 35–37, 39, 46
3D and 4D printing, 110–112
THPC, 410–411
TiO
nanoparticles, 302
2
Tissue engineering, 26, 28–36, 38, 40, 41, 43,
45–49, 77, 78, 80, 82, 89, 91, 92, 96,
135, 136, 140, 141, 148, 149, 166–168,
174–179, 220, 222–226, 228, 231, 233,
234, 242, 374, 377, 379, 382
Transition metal dichalcogenides (TMDCs),
224–226
Transmission electron microscopy (TEM), 360,
361
Trolox equivalent antioxidant capacity (TEAC),
288
Tympanic membrane (TM), 207
U
UV-Vis spectrum, 283, 284
V
etection, 296
Virus d
Vitronectin, 11

Index 433
W
Water annealing, 198, 200–202, 208
World heritage, 276, 281–289
Wound
dressings, 30, 39–41
Wound healing, 28–30, 32, 39–42, 44, 46, 77,
78, 80, 87, 89, 91, 92, 94–96, 220, 225,
228, 233, 235, 242
X
X-ray diffraction (XRD), 360, 361
Y
Yamato, 282, 283, 289
Z
Zeolite, 2
Zinc oxide
20, 226, 2
35, 240, 241
nanoparticle, 262–264
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