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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_1116_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Foreword
- •Preface
- •Acknowledgments by Salman Al-Sabah
- •Contents
- •Editors and Contributors
- •Introduction
- •Learning About the Laparoscopic Sleeve Gastrectomy (lSG) The Birth and Evolution of Laparoscopic Sleeve Gastrectomy
- •1 Introduction
- •2 Costing Methods
- •3 Costing Components
- •4 Cost of Obesity and Overweight: The Evidence
- •5 Overall Cost of Obesity
- •6.1 Ischaemic Heart Disease and Stroke
- •References
- •Obesity, a Costly Epidemic
- •6.2 Diabetes Mellitus
- •6.3 Osteoarthritis
- •6.4 Cancers
- •7 Conclusion
- •References
- •The Health Effects of Obesity
- •1 Obesity Reduces Life Expectancy
- •2 Obesity and Cardiovascular Disease
- •3 Obesity and Respiratory Disease
- •4 Obesity and Cancer
- •5 Other Obesity-Related Conditions
- •6 Health Effects of Obesity in Special Populations
- •6.1 Transplant Recipients
- •6.2 Orthopedic Surgery Patients
- •6.3 Pregnancy
- •6.4 Children and Adolescents
- •7 Conclusion
- •References
- •Obesity and Body Mass Index
- •2 Obesity and BMI
- •3 Percent Excess Weight Loss (%EWL)
- •4 Percent Excess BMI loss (%EBMIL)
- •5 Percent of Total Weight Loss (%TWL)
- •References
- •Dealing with Obesity: Patient Perspective
- •1 Considering the Psychology of Obesity
- •2 Education for Success
- •3 Understanding the Necessity of Mind Shift for Success
- •The Future of Bariatric Surgery and Genetics
- •1 Heritability and Obesity
- •2 Weight Loss Interventions and Genetics
- •3 Bariatric Surgery and Genetics
- •References
- •Sleeve Gastrectomy Registries
- •1 Introduction
- •3 The Value of Registries
- •7.1 Direct-Data Entry Only
- •7.2 Electronic Upload Only
- •8 Key Step 5—Create a Suitable Minimum Dataset
- •9 Key Step 6—Layer in GDPR Compliance
- •14 Conclusion
- •References
- •Weight Loss: Diet Options
- •1 Introduction
- •2 Principles in Dietary Therapies
- •3 Diet Options for Weight Loss
- •4 The Weight-Maintenance Diet
- •5 Summary
- •References
- •Candidates for Sleeve Gastrectomy
- •Eligibility Criteria for Sleeve Gastrectomy
- •1 Introduction
- •2 Current Eligibility Criteria for Bariatric Surgery
- •3 Age
- •4 BMI
- •5 Procedure Selection
- •6 Other Considerations in Decision-Making
- •7 Summary
- •References
- •The Sleeve and Pregnancy
- •1 Pre-pregnancy Weight Management
- •2 Pre-pregnancy Supplementation
- •3 Acceptable Weight Changes in Pregnancy
- •4 Care During Pregnancy
- •5 Gestational Diabetes
- •5.1 Screening
- •5.2 Treatment
- •5.3 Mode of Delivery
- •5.4 Postpartum
- •References
- •The Sleeve and Reproductive Potential
- •1 Introduction
- •2 Obesity and Female Reproduction
- •3 Obesity and Male Reproduction
- •4 Female Reproduction Following Bariatric Surgery
- •5 Male Reproduction Following Bariatric Surgery
- •6 Timing of Conception Following Bariatric Surgery
- •8 Conclusion
- •References
- •6 RYGB to SG
- •7 SG After Endoscopic Procedures
- •8 Conclusion
- •References
- •Converting Endoscopic Bariatric Procedures to LSG: POSE, Endosleeve, and Balloon
- •1 Introduction
- •The Sleeve as a Revisional Procedure
- •1 Introduction
- •2 General Considerations
- •3 Choice of Technique Based on Evidence
- •5 Sleeve Gastrectomy to Re-sleeve
- •2 The POSE Procedure
- •2.1 How the POSE is Performed
- •2.2 Converting a POSE to an LSG
- •3 The Endosleeve
- •3.1 How the Endosleeve is Performed
- •3.2 Converting Endosleeve to LSG
- •4 The Balloon
- •4.1 LSG Following Balloon Removal
- •5 Conclusion
- •References
- •The Sleeve Gastrectomy in Adolescents
- •1 Introduction
- •2 Eligibility
- •2.1 Who is Eligible?
- •3 Which Procedure is Right for Adolescents
- •4 Pre- and Post-operative Nutritional Care
- •5 Psychological Concern
- •6 The Outcomes of SG
- •References
- •2 Epidemiology
- •3 Risk Factors
- •4 Pathophysiology
- •5 Clinical Presentation
- •6 Diagnosis
- •7 Non-invasive Tests
- •7.1 Laboratory Investigations
- •7.2 Imaging
- •8 Scoring Systems
- •8.1 Invasive Measure
- •8.1.1 Liver Biopsy
- •9 Clinical Scores
- •10 Sleeve Gastrectomy in NAFLD and NASH
- •13 Sleeve Gastrectomy Pre-transplant
- •15 Sleeve Gastrectomy After Liver Transplantation
- •References
- •Sleeve Gastrectomy in Immunocompromised Patients
- •1 Introduction
- •2 Safety and Postoperative Morbidity
- •2.2 Perioperative Timing of Immunosuppressive Therapy
- •3 Outcomes of SG in Immunocomromised Patients
- •3.2 Changes to Rheumatoid and Autoimmune Conditions
- •4 Summary
- •References
- •Sleeve Gastrectomy and Cancer
- •1 Obesity and Cancer
- •2 Pathogenesis of Cancer in the Obese
- •3 Current Literature
- •4 Bariatric Surgery and Cancer Risk
- •5 Colorectal Cancer (CRC)
- •6 CRC in RYGB Versus SG and AGB
- •7 Breast and Endometrial Cancers
- •8 SG and Gastro-esophageal Cancer
- •9 Conclusion
- •References
- •Multidisciplinary Care Before and After Sleeve Gastrectomy
- •1 Introduction
- •2 Bariatric/Obesity Specialist
- •3 Bariatric Dietitian
- •4 Bariatric Clinical Psychologist
- •5 Bariatric Coordinator
- •6 Conclusion
- •References
- •Psychiatric Evaluation: Pre and Post Sleeve
- •1 Introduction
- •3 Depression
- •4 Eating Disorders
- •5 Anxiety
- •6 Substance Use Disorders
- •7 Self-harm and Suicidal Ideation
- •8 Psychotropic Medications
- •10 Mental Health Preoperative Assessment
- •11 Outline of Domains of the Evaluation
- •12 Psychiatric Contraindications for Bariatric Surgery
- •13 Conducting the Assessment
- •13.1 History of Weight Loss and Previous Attempts
- •13.2 Medical History
- •13.3 Pathological Eating Behavior
- •13.4 Psychiatric History and Screening of Substance Use
- •13.5 Support System
- •13.6 Psychiatric Medication
- •14 Psychiatric Assessment Conclusion
- •15 Special Populations
- •15.1 The Adolescent Patient
- •15.2 Limited Cognitive Function
- •16 The Impact of Bariatric Surgery on Mental Health
- •16.1 Quality of Life
- •16.2 Mental health status
- •16.3 Suicide
- •16.4 Addiction
- •16.5 Eating Disorders
- •16.6 Psychotropic Medication
- •16.7 Postoperative Pharmacological Considerations
- •17 Conclusion
- •References
- •Insurance, Self-Pay and Medical Tourism
- •How Much Does the Sleeve Cost
- •1.1 Economic Methodologies
- •1.2 Fixed Costs: Medical Devices
- •1.3 Fixed Costs: Personnel
- •1.4 Variable Costs: Reusable Instruments
- •1.5 Variable Costs: Disposables
- •2 Bariatric Surgery Costs
- •2.1 Methods for Identifying Cost Components
- •2.2 Methods for Valuing Cost Components
- •3 The Cost of the Sleeve Around the World
- •References
- •Analysis of LSG Competitors
- •1 Competition in the Industry
- •2 Potential of New Entrants into the Industry
- •3 Threat of Substitute Products
- •3.1 Anti-obesity Medications
- •3.2 Herbal and Alternative Medicine
- •3.3 Diet Program
- •3.4 Exercise
- •3.5 Acupuncture and Acupressure for Weight Loss
- •4 Power of Customers
- •5 Power of Suppliers
- •5.1 Strengths
- •5.2 Weaknesses
- •5.3 Weaknesses of Duodenal Switch Surgery
- •5.4 Opportunities
- •5.5 Threats
- •References
- •Medical Tourism: Global Bariatric Healthcare
- •1 Introduction
- •2 The Impetus Behind Global Healthcare
- •4 Conclusion
- •References
- •Sleeve Gastrectomy: Medicolegal Aspects
- •References
- •Laparoscopic Sleeve Gastrectomy 101
- •References
- •Robotic Sleeve Gastrectomy
- •1 Introduction
- •2 Robotic-Assisted Sleeve Gastrectomy
- •3 Cost of Robotic-Assisted Sleeve Gastrectomy
- •5 Operative Technique
- •6 Clinical Outcomes
- •7 Future Directions
- •8 Conclusion
- •References
- •Laparoscopic Sleeve Gastrectomy in Situs Inversus Totalis
- •1 Introduction
- •2 How to Perform the Procedure
- •3 Discussion
- •4 Conclusion
- •References
- •Banded Sleeves
- •1 Introduction
- •2 Procedure
- •3 Pre- Intra- and Post-Operative Management
- •4 Results
- •5 Band Complications
- •7 Conclusions
- •References
- •Buttressing the Sleeve
- •1 Introduction
- •2 Technical Aspects
- •3 Buttressing for Bleeding
- •4 Buttressing for Leaks
- •5 Results from the MBSAQIP
- •6 Previous Evidence
- •7 Conclusion
- •References
- •Sleeve and Ventral Hernias
- •1 Introduction
- •2 Prevalence, Incidence and Cost of Ventral Hernia
- •4 Primary Abdominal Wall Hernia
- •5 Incisional Hernia
- •5.1 Medial or Midline Zone
- •5.2 Lateral Hernias (Flank Hernias)
- •6 Size of the Hernia
- •7 Indication and Risks of Ventral Hernia Repair
- •8.1 Position of Trocar and Creation of Pneumoperitoneum
- •9 Principles of Adhesiolysis
- •10 Measurement of Hernia Defect
- •12 Technique of Open Ventral Hernia Repair [10, 25, 26]
- •13 Concurrent LSG with LVHR
- •14 LSG with Sequential LVHR
- •15 Conclusion
- •References
- •1 Introduction
- •5 Operative Concerns and Patient Selection
- •6 Preoperative Evaluation
- •7 Esophageal High-resolution Manometry
- •8 Surgical Technique
- •9 Discussion
- •References
- •Omentopexy in Laparoscopic Sleeve Gastrectomy
- •1 Background
- •3 Omentopexy in Sleeve Gastrectomy
- •3.2 Operative Technique
- •5 Effect on Gastric Emptying
- •6 Conclusion
- •References
- •Sleeve Gastrectomy and Gallstones Disease
- •1 Introduction
- •2 Obesity and the Risk of Gallstone
- •3 Rapid Weight Loss and the Risk of Gallstone
- •5 Incidence of Cholecystectomy in Sleeve Gastrectomy
- •6 Biliary Complications Post LSG
- •7 Cholecystectomy: When to Operate?
- •8 Prophylactic (Routine) Cholecystectomy
- •9 Elective (Selective) Cholecystectomy:
- •11 Ursodeoxycholic Acid (UDCA) Prophylaxis
- •12.1 Dose, Frequency
- •13 Disadvantages of UDCA
- •14 Summary
- •15 Conclusion
- •References
- •LSG Under Block Anesthesia (PVB)
- •1 Introduction
- •2 Review on General Anesthesia
- •2.1 General Overview
- •2.2 General Anesthesia in the Obese/bariatric Population
- •3 Review on Paravertebral Block (PVB)
- •4 Anatomy
- •4.1 Indication
- •4.2 Techniques
- •4.2.1 Blind Technique
- •4.2.2 Neurostimulation Technique
- •4.2.3 Ultrasound Guided Technique
- •4.3 Mechanism and Spread of Anesthetic
- •4.4 Anesthetic Drugs
- •4.5 Complications
- •4.6.1 Abdominal Surgeries
- •4.6.2 First Paravertebral Block in Sleeve Gastrectomy
- •References
- •Elderly High Risk Patients Undergoing Laparoscopic Sleeve Gastrectomy
- •1 Scope of the Problem
- •1.1 Increasing of the Elderly Population
- •1.3 Risks of Surgery in the Elderly
- •1.3.1 Bariatric Surgery in Elderly
- •2 Sleeve Gastrectomy: Procedure of Choice
- •2.1 Intraoperative Difference in Elderly
- •3 Postoperative Care in the Elderly
- •4 Postoperative Mortality and Morbidity
- •5 Postoperative Outcomes
- •5.1 Excess Body Weight Loss
- •5.2 Comorbidities Improvement
- •5.3 Quality of Life Improvement
- •6 LSG in Septuagenarians and Elderly Super Obese
- •7 LSG Compared to Gastric Bypass in Elderly
- •8 Conclusions
- •References
- •Postoperative Diet Progression for Laparoscopic Sleeve Gastrectomy
- •1 Introduction
- •2 Diet Progression: Stages
- •3 Conclusion
- •References
- •How Laparoscopic Sleeve Gastrectomy May Cause Weight Loss
- •1 Ghrelin Effect
- •1.1 Other Gastrointestinal Hormone Secretion
- •1.2 Other Molecular Changes
- •1.3 Bile Acid Metabolism
- •1.4 Microbiome
- •1.5 Central Nervous System Changes
- •1.6 Conclusion
- •References
- •Expected Weight Loss After the Sleeve
- •1 Introduction
- •2 Preoperative Weight Loss
- •3 Short-Term and Mid-Term Outcomes
- •4 Long-Term Outcomes
- •6 Summary
- •References
- •1 Introduction
- •2 Set Point Theory
- •3 Weight Regulation and Weight Loss Maintenance
- •6 Neurohormonal Regulation of the Body Set Point
- •8 Conclusions
- •References
- •Quality of Life and Bariatric Surgery
- •1 Medical Outcomes Survey Short Form 36S (SF-36)
- •3 The Bariatric Quality of Life Index (BQL)
- •References
- •LSG: Risks and Considerations
- •Risks Associated with Sleeve Gastrectomy
- •References
- •Outcomes and Complications After Sleeve Gastrectomy
- •1 Introduction
- •2 Impact on Obesity
- •3 Impact on Diabetes
- •4 Impact on Hypertension
- •5 Impact on Dyslipidaemia
- •6 Complications
- •7 Non-Surgical Complications of Sleeve Gastrectomy
- •9 Early Complications of Sleeve Gastrectomy
- •10 Alteration to Bile Flow After Sleeve Gastrectomy
- •11 Anatomical Changes After Sleeve Gastrectomy
- •12 Vagus Nerve Modulation After Sleeve Gastrectomy
- •13 Cardiovascular Effects of Sleeve Gastrectomy
- •14 Effects on Microbiota After Sleeve Gastrectomy
- •15 Impact on Metabolism After Bariatric Surgery
- •16 Conclusion
- •References
- •How to Manage Sleeve Complications: Hemorrhage
- •1 Background
- •2 Bleeding Cascade, Patient and Surgeon Factor
- •3 Surgical Stapler Technology
- •4 Management and Prevention
- •4.1 Buttressing, Oversewing
- •5 Hemostats
- •6 Summary
- •References
- •Endoscopic Management of Leak and Abscess Following Laparoscopic Sleeve Gastrectomy
- •1 Introduction
- •3 Closure of the Leak Site
- •3.1 Self-Expanding Metal Stents
- •3.2 Types of SEMS
- •3.3 SEMS Insertion Procedure
- •3.4 Outcome of SEMS Placement
- •3.5 Over-The Scope Clip System
- •4 Internal Drainage
- •4.1 Endoscopic Internal Drainage
- •4.2 EID Procedure
- •4.3 Outcome of EID Procedure
- •4.4 Endoscopic Vacuum Therapy
- •5 Septotomy and Pneumatic Balloon Dilatation
- •6 Conclusion
- •References
- •How to Manage Sleeve Complications: Surgical Leak and Abscess
- •1 Introduction
- •2 Principles of Management
- •3 Endoscopy
- •4 Surgery
- •4.1 Control of Early Complications and Nutritional Status
- •4.2 The Leak Site
- •4.3 Roux en Y Fistulo-Jejunostomy
- •4.4 Literature Review of the Remaining Surgical Options
- •4.5 Discussion of the Surgical Approach
- •5 Conclusion
- •References
- •How to Manage Sleeve Complications Through Endoscopy: Strictures
- •1 Introduction
- •4 Signs and Symptoms
- •5 Diagnosis and Management
- •6 Bougie Dilation
- •8 Self-Expanding Metal Stent (SEMS) Placement
- •10 Strategies for Endoscopic Success
- •11 Conclusions
- •References
- •Sleeve Gastrectomy Stenosis: Surgical Treatment
- •1 Introduction
- •2 Diagnosis
- •3 Incidence
- •4 Prevention
- •5 Treatment
- •6 Conclusion
- •References
- •1 Introduction
- •2 Mechanisms of GERD Post-Sleeve Gastrectomy
- •3 Incidence of GERD After Sleeve Gastrectomy
- •4 Screening Recommendations
- •5 Role of Pharmacotherapy, Diagnosis, and Testing
- •7 Radiofrequency Ablation
- •8 Transoral Incisionless Fundoplication (TIF)
- •9 Conclusion
- •References
- •1 Background
- •2 Pathophysiology

J. S. Dababneh200
5 Power of Suppliers
Not all bariatric surgeons perform every procedure; Not all hospitals provide these
surgeries.
Therefore, suppliers exert low to medium bargaining power in this domain.
What about the SWOT (Strengths, Weaknesses, Opportunities and Threats)
analysis?
5.1 Strengths
Gastric Bypass Surgery: has a long history of success and clinical studies to validate its effectiveness [1, 2].
• Average Excess Weight Loss: 60–80%
• Serious Complication Rate: 1.25%
• Average 30 Day Mortality Rate (Death Rate): 0.14%
• May reduce hunger.
• Excellent rate of diabetes cessation after surgery.
• May relieve heartburn and acid reflux.
Gastric Sleeve Surgery [3, 4]:
• Average Excess Weight Loss: 57–70%
• Serious Complication Rate: 0.96%
• Average 30 Day Mortality Rate (Death Rate): 0.08%
• An average hospital stay of 2 nights, but in some cases, can be performed as an
outpatient procedure.
• May reduce hunger.
• No foreign objects like that with Lap Bands.
• No re-routing of the intestines as seen with gastric bypass.
• A straightforward procedure that is relatively easy to replicate.
Duodenal Switch Surgery [5]:
• Average Excess Weight Loss: 80–90%
• Serious Complication Rate: 2–3%
• Average Mortality Rate (Death Rate): 0.29–2.7%
• The best weight loss profile, up to 85% excess weight loss.
• The best long-term weight loss success rate (better than 50% excess weight
loss) of 95%.
• Best rate of comorbidity reduction.

Analysis of LSG Competitors
201
5.2 Weaknesses
There are trade-offs. Bariatric surgery carries some long-term risks for patients,
including: Dumping syndrome, a condition that can lead to symptoms like nausea
and dizziness. Low blood sugar and malnutrition.
Bypass is more effective for weight loss, but has a greater risk of short-term
complications.
It is a technically challenging procedure and typically requires longer time
under anesthesia compared to other popular bariatric surgeries.
There is a risk of long-term nutritional deficiencies. Vitamins and minerals are
required for life. However, the risk of vitamin and mineral deficiencies is lower
than the duodenal switch and gastric bypass.
5.3 Weaknesses of Duodenal Switch Surgery
Duodenal Switch surgery is not a new surgery, many surgeons avoid it and prefer
LSG to it, due to the following complexities:
• The highest risk for malnutrition.
• Strictest dietary guidelines.
• The longest and most complex procedure of the three primary bariatric proce-
dures (bypass, sleeve, and duodenal switch).
• Highest 30-day serious complication rate.
• Strict adherence to vitamins and minerals and post-operative diet are required
for success and to prevent malnutrition.
However, it is important to keep in mind that these complexities are not permanent. Lifestyle changes are paramount for lasting weight loss for any procedure
and must be made clear to all patients before undergoing bariatric surgery. When
considering gastric balloons, patients can expect 10 to 30% excess weight loss.
5.4 Opportunities
According to data from the Centers for Disease Control and Prevention (CDC),
over a third of adults in the United States live with obesity.
Obesity is the next major epidemiologic challenge facing today’s doctors, with
the annual allocation of healthcare resources for this disease and related comorbidities projected to exceed $150 billion in the United States.
Furthermore, the incidence of obesity has risen in the United States over the
past 30 years; it has been shown that 60% of adults are currently either obese or
overweight.

J. S. Dababneh202
Obesity is associated with a higher incidence of a number of diseases, including diabetes, cardiovascular disease, and cancer.
Consumption of fast food, trans fatty acids (TFAs), and fructose—combined
with increasing portion sizes and decreased physical activity—has been implicated
as a potential contributing factor in the obesity crisis.
5.5 Threats
New procedures are entering this market e.g. Gastric Balloons are a new tool for
patients with a Body Mass Index (BMI) of 30–40 that want to lose weight but do
not want to have surgery.
This new option now offers the patient a pill to swallow, and a balloon is then
inflated and left in the stomach for six months. This results in reduced hunger and
an increase in the feeling of satiety.
References
1. Phillips E, Ponce J, Cunneen SA, et al. Safety and effectiveness of REALIZE adjustable gas-
tric band: 3-year prospective study in the United States. Surg Obes Relat Dis. 2009;5:588–97.
2. Tice, et al. Gastric banding or bypass? A systematic review comparing the two popular proce-
dures. Am J Med. 2008;121:885–93.
3. O’Brian P, et al. Systematic review of medium-term weight loss after bariatric surgery. Obes
Surg. 2006;16:1031–40.
4. Tice JA, Karliner L, Walsh J, et al. gastric banding or bypass? A systematic review comparing
the two most popular procedures. Am J Med. 2008;121:885–93.
5. Cottam et al. A case-controlled match-paired cohort study of lap. RNY gastric bypass and lap
band patient in a single US center with three year follow up. Obes. Surg. 2006;16: 534–40.

Medical Tourism: Global Bariatric Healthcare
Ahmad Bashir
1 Introduction
With the increase in world connectivity and ease of travel, ASMBS issued its position statement on medical tourism in bariatric surgery calling it ‘Global Bariatric
Healthcare’ [1]. They feared the term ‘Medical Tourism’ would not accurately
describe all the issues or concerns associated with bariatric surgery. They defined
global bariatric healthcare as “travel to undergo bariatric surgery across any distance that precludes routine follow-up and continuity of care with the surgeon or
program”. Any distance associated with such conditions, was seen to fulfill this
definition, even if within the same country, across cities, regions or states.
Based on commercial estimates, in 2018, the medical tourism market size was
valued at 36.9 billion USD [2]. It is projected to be 179.6 billion USD by 2026,
not including all potential countries, suggesting that physicians, societies and medical industry should put more emphasis on studying this sector, along with working to decrease the risks, concerns and burdens associated with it.
The number of publications addressing medical tourism has been increasing
exponentially since 2004 (Fig. 1), in line with the increase in value mentioned
above. However, there are plethora of areas for potential research to understand
the realities of this sector. In this chapter, we will try to review the available literature to understand the impact of global bariatric healthcare on bariatric surgery
outcomes worldwide, while identifying the areas of deficiency to promote more
research to address them.
A. Bashir (*)
Gastrointestinal, Bariatric and Metabolic Center (GBMC), Jordan Hospital, Amman, Jordan
e-mail: ahmad.bashir.md@gmail.com
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer
Nature Switzerland AG 2021
S. Al-Sabah et al. (eds.), Laparoscopic Sleeve Gastrectomy,
https://doi.org/10.1007/978-3-030-57373-7_22
203

A. Bashir204
Fig. 1 Pubmed publications 1957–2019 on ‘Medical Tourism’—CSV file obtained from pumed.
com
2 The Impetus Behind Global Healthcare
The incentives behind the global healthcare growing vary according to different
perspectives. From the eyes of surgeons accepting medical tourism; patients travel
seeking bariatric surgery due to higher cost of care in the private sector of their
own country, with long waiting lists within their national health system, lack of
insurance coverage for bariatric surgery or lack of service providers able to perform bariatric surgery [3]. In a survey by Kowalewski et al. in which 93 bariatric
surgeons from thirty-three countries responded to, bariatric surgery costs ranged
from 2,300 to 35,000 USD with a mean of 7760 USD (±4035). The cost of treatment correlated weakly with gross domestic product GDP, influencing the flux of
patients to nearby countries with lower cost of care as mentioned in several patterns within the survey (Fig. 2). This phenomenon is not unique to bariatric sur-
gery, as it is noted in cosmetic surgery, fertility medicine, dental care, transplant,
orthopedic surgery among several others [4].
The patients’ view is similar, however with more barriers. Snyder et al. [5]
interviewed patients who pursued care outside Canada (9% undergoing bariatric
surgery). Long wait times for necessary procedures were seen as unethical and the
primary driver for patients to seek treatment abroad. Having the ability to travel
for treatment heightened the patients sense of control, as they felt justified to do
so. Patients perceived the health system, in their study, as stifling to surgeons’ ability to innovate, as it lacks the proper incentives to do so. Canada provided coverage for patients to undergo bariatric surgery in the United States in the recent
past [6]. As the need for regional and local ability to provide these services was
recognized, the country invested in building these services. However, the long

Medical Tourism: Global Bariatric Healthcare
205
Fig. 2 Flux of patients in different regions by Kowalewski et al. [3]—copyrights to Springer

A. Bashir206
wait times of 5 years at times, with 1% out of 20% suffering from obesity getting
access to care seems to drive patients to travel outside despite the patients having
to pay out of pocket to undergo bariatric surgery [7]. Jackson et al. [8] showed
that patients experienced all of the above barriers: long wait time, strict criteria for
surgery, on top of limited options in certain areas, which incentivized them to seek
different treatment abroad.
In the United Kingdom (UK), Hanefeld et al. [9] reported besides all of the
mentioned above, the patients’ lack of trust towards the National Health System
(NHS) while on the waiting list for bariatric surgery. Informal networks, support
groups and patient referrals seemed to boost the process of traveling abroad once
trust is established with a physician accepting medical tourism. Providers abroad
tended to have networks within the UK, and some would offer follow up even in
the UK.
As for the effect of the industry, Sa Dang et al. [10] recently showed the impact
of economy and competition in the medical tourism industry among six south-east
Asian countries. In addition to excellent innovative and relatively cheaper medical
services, additional tourism activities are a factor in driving more patients to that
region. Healthcare facilities and infrastructure, together with the quality of medical tourism providers are the first conditions to any traveler, prior to considering
lower costs of care. Governments in those countries play a major role in reducing
other burdens: providing educational information on the travel experience, lower
air fare costs, tax returns, and travel insurances. Among many reports, Thailand
seemed to perform best among countries in that region. Cosmetic surgery is the
number one reason to travel to Thailand, but bariatric surgery is second on the list
and gaining momentum as a reason to travel [2], although this differs according to
the different sources (Fig. 3 and Table 1).
In a systemic review of ‘Patient care without borders’, Foley et al. [11] also
recognized the cultural proximity as a motive for patients to travel to destinations
with similar language, culture and values. The positive economic impact has influenced more job creation, with additional sectors developed and geared towards
promoting and facilitating medical tourism.
Sleeve gastrectomy, as a procedure, may have contributed to the increase in
medical tourism. Kowalewski et al. [3] reported that the number one procedure
offered to patients seeking bariatric surgery abroad, was sleeve gastrectomy in
89.1% of surgeons surveyed. Worldwide, sleeve gastrectomy is the number one
procedure done among all bariatric procedures [12]. The procedure’s relative
simplicity and steep learning curve (easier to learn) [13] also led to an increase
in number of surgeons offering bariatric surgery [14], with many being sleeve
only surgeons [15]. One can only include with these factors, that the procedure
increased access to care along with increasing number of bariatric tourists undergoing this procedure.
Rokni et al. [16] summarized all of these into push and pull factors: push factors pushing patients away from their current national health system, while pull
factors pulling them into another medical tourism healthcare system or provider
(Table 2).

Medical Tourism: Global Bariatric Healthcare
Fig. 3 Top 10 worldwide destinations according to (AJN ▼ July 2017 ▼ Vol. 117, No. 7):
From left to right: India, Malaysia, Thailand, Turkey, Costa Rica, Mexico, Taiwan, South Korea,
Singapore and Brazil. The percentage ranges above each bar indicate cost saving range of receiving medical treatment in each country compared to receiving it in USA. Image courtesy in the
report was given to IgeaHub.com (no longer active). If displaying this image is not feasible, then
the second option below
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Table 1 Top ten medical tourism destinations, based on value and numbers
Top ten medical tourism destinations
by value
USA 3,500 Malaysia 900
South Korea 655 USA 500
Turkey 600 South Korea 365
Thailand 600 Thailand 350
Germany 575 Dubal 350
India 450 South Africa 300
UK 350 Taiwan 300
Malaysia 350 Germany 255
Mexico 350 Mexico 250
Iran 315 Turkey 200
Source [16] Rokni et al. adopted from medical tourism and travel market briefing 2018
US $m Top ten medical tourism destinations
by numbers
000K

A. Bashir208
Table 2 Pull and Push factors
Pull factors
Low-cost High cost of private treatment
High-quality healthcare Inefficient healthcare system
Expert physicians Limited access to care
Cultural similarities Lack of several professional treatments
Geographical proximity Lack of trust in the national system
Touristic attractions with tourism support Geographical, political or safety concerns
Level of trust
Push factors
3 The Deficiencies, Downside and Upside of Medical
Tourism
Unfortunately, the countries with national health systems with long waiting lists,
are on the receiving end of their own residents returning at times with complications, after undergoing bariatric or other procedures elsewhere. Before we delve
into such reports, it is important to note that patients doing well otherwise are possibly not well represented in the medical literature, as they either follow up with
their primary care only, or are just not following up with any physician. Eventually
patients tend to seek medical advice if they are vigilant on maintaining their good
health, or are experiencing a health problem. Those who only see physicians due
to a health problem, will never do so if they are well in their own opinion. This
raises the possible matter of medical tourism being impacted with a larger number
of negative publications, especially among the countries on the receiving end of
complications.
Foley et al. [11] in their systemic review recognized the challenges of having
a current well-defined denominator of the number of patients inflowing or outflowing. Several survey studies are limited to specific number of medical tourism
providers, without the ability to extrapolate the entire number. Noree et al. [17],
showed conflicting numbers between the origin (UK) and recipient (Thailand)
countries on the number of patients and types of procedures performed. This confusing conflict in the literature, has led to difficulty in estimating accurate costs,
revenue and health outcomes. Commercial reports are also said to overestimate
the industry, but without any alternative, several studies quoted these numbers and
possibly misrepresented the reality.
Sheppard et al. [18] estimated that the complication rate of medical tourism
within Alberta, Canada ranged between 42.2 and 56.1%, a leak rate alone of 12.8–
17%, an estimate that far exceeds the complication rate of bariatric surgery performed of 16.6% in Alberta. Venous thromboembolic events (VTE) occurred 4–6
times higher in tourist patients. They estimated that the cost of these complications
to exceed performing 250 bariatric procedures within Alberta and managing their

Medical Tourism: Global Bariatric Healthcare
209
potential complications. Their group showed similar results again in 2016 [7].
Unfortunately, bariatric tourists returning home with acute complications, may end
up in non-specialized hospitals without proper knowledge of bariatric complications, which may worsen their outcome. This has led some to educate general surgeons on various bariatric procedures, their complications and how to effectively
deal with them [19].
Unique bacterial infections have been reported away from bariatric surgery
[20]. Usually the ones reported are either rare otherwise or multidrug resistant.
Among transplant tourism utilizing commercial organs, this was highest.
In patients from relatively poorer countries seeking treatment when local expertise is not present, a good portion would end up paying catastrophic amount of
money leading to a huge financial burden on the individual, family and even the
society where patients reside [20].
Other social difficulties were reported by Awano et al. [21] in Japan. Language
barriers, inadequate or inaccurate referral information, difference in cultural habits
led to more confusion in some patients, with a few going elsewhere for treatment.
Caregiver-companions; family or friends traveling with medical tourists, also face
a great burden while abroad [22]. They have a heightened sense of responsibility,
with most feeling vulnerable emotionally and strained financially if complications
occur while abroad.
Perhaps one of the major criticisms of the ethical side of the tourism industry,
is the lack of proper informed consent on potential risks of medical tourism [11].
Only 11.7% of a Canadian broker sites reported in Foley et al. review, mentioned
the risks properly. Although the risks in the literature may be overstated, they felt
the current status had to be mentioned and the tourism sites have to be encouraged
to share their outcomes.
Still, several gaps exist that need to be addressed in research. This has led some
as Peters et al. [23] to call for national bariatric tourism registry to define the
actual cohort of patients seeking bariatric tourism. Till then, together with ASMBS
position statement [1], they suggested increasing patients awareness on risks, identifying good providers within a Joint Commission International (JCI) accredited
healthcare facility, while enforcing payers to maintain continuity of care with
maintaining access to complications.
With all negatives mentioned above, there is still an upside to medical tourism. The economic upside as mentioned above, with expected growth to countries
investing in health tourism [2, 10, 23]. This may aid in decreasing costs to healthcare for locals. It also may improve the level of overall care provided.
The overall access to care with decrease in the burden of overall wait time
can be achieved at a lower cost, if complication rates were low or minimized. A
standard enforced by societies together with a unified global registry may aid in
identifying profile of patients seeking bariatric tourism with their true outcomes.
Established registries, such as American College of Surgeons (ACS) National
Surgery Quality Improvement Project (NSQIP) or Metabolic & Bariatric Surgery
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