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5 Imaging-Based Navigation: Applications Beyond Instrumentation
Fig. 5.22 Tumor resection planning 1
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Fig. 5.23 Tumor resection planning 2
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Fig. 5.24 Tumor resection planning 3
K. S. Heidari and C. J. Kleck
Fig. 5.25 Tumor resection planning 4
5 Imaging-Based Navigation: Applications Beyond Instrumentation
Fig. 5.26 Tumor resection planning 5
Fig. 5.27 Postoperative
PA radiograph
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Fig. 5.28 Postoperative lateral radiograph
K. S. Heidari and C. J. Kleck

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K. S. Heidari and C. J. Kleck
Chapter 6
Imaging-Based Navigation: Summary ofClinical Results
JohnWhitaker andDavidOu-Yang
Early Development andInitial Navigation Systems
Spinal navigation software originated from stereotactic neurologic surgery. The Brown-Roberts-Wells frame and software were rst described in 1979 [1]. This technique was created to allow surgeons to extrapolate information from preopera­tive computerized tomography (CT), magnetic resonance, or positron-emission tomography images and use it intraoperatively to increase surgical precision. This was of particular interest for intracranial lesion resection. In 1986, Roberts etal. rened this technology by using a stereotaxic frame to overlay these preoperative images onto the operating eld underneath a microscope [2].
The rst report describing navigation software in spinal surgery was published in 1995 by Nolte etal. [3]. This is represented in Fig.6.1. In that same year, Lavelle etal. described the implementation of this software for the placement of pedicle screws on a cadaveric specimen [5]. This paper described their process of transfer­ring preoperative CT scan information into the placement of pedicle screws. The surgeon would set the ideal trajectory of the pedicle screw based on the patient’s preoperative imaging, and then calibrated instrumentation allowed for placement in this trajectory.
One of the largest comparative evaluations of this technology was performed by Amiot et al. [6]. This study evaluated 544 conventionally placed pedicle screws inserted from T5 to S1 versus 294 computer-assisted pedicle screws from T2 to S1. They examined accuracy of placement, neurologic compromise from screw place­ment, and location of improperly placed screws. They concluded that there was a signicant increase in the accurate placement of pedicle screws using computer­assisted insertion (85% vs. 95%). There were seven patients in this series that
J. Whitaker (*) · D. Ou-Yang Division of Spine Surgery, Department of Orthopedic Surgery, School of Medicine, University of Colorado, Boulder, CO, USA
Switzerland AG 2024 S. Garg, C. J. Kleck (eds.), Navigation, Robotics and 3D Printing in Spine Surgery, https://doi.org/10.1007/978-3-031-68678-8_6
73© The Author(s), under exclusive license to Springer Nature
74
Fig. 6.1 Fluoroscopic-guided navigation [4]
J. Whitaker and D. Ou-Yang
required re-treatment for neurologic compromise from misplaced screws in the con­ventional group compared with none in the navigation group. All misplaced screws placed under navigation assistance were within 2mm of the pedicle cortex, while there was a signicantly larger variation in the conventional group (>6.0mm of variation). The ndings of this study supported several other earlier studies. Merloz etal. reported in 1997 that there was a signicant increase in the accuracy and reli­ability of pedicle screw placement in the thoracic spine as compared to conventional techniques for placement [7]. Schwarzenbach etal. examined the success of pedicle screw placement using the Orthopedic Surgery Planning System. This study also determined that there was increased accuracy and precision in placing pedicle screws [8]. Interestingly, this study did not demonstrate an increase in accuracy of screw placement over time; however, they did note that there was improved ef­ciency in system use over time. Regarding a learning curve, Amoit etal. did not demonstrate any evidence of a learning curve effect over their 3-year experience [6].

Fluoroscopic-Guided Navigation Systems

Conventional uoroscopy using a C-arm has been a staple for pedicle and lateral mass screw placement in spinal surgery. Fluoroscopy is also readily available in most facilities and the use and set-up are familiar to the operating room staff. Fluoroscopic navigation systems rely on conventionally obtained intraoperative uoroscopic images. These are stored and compiled through the navigation plat­form, and then placed in an overlay for the surgeon to visualize the instrumenta­tion’s trajectory and depth. These advantages make uoroscopy a convenient modality to augment freehand screw placement. Freehand pedicle screw placement has been associated with screw misplacement rates as high as 40%. With supple­mentation of standard uoroscopic imaging, this rate can be lowered to 3.4% [9]. This utilization of uoroscopy is not without signicant drawbacks. Radiation exposure to the neck is 8.3 mrem/min and to the torso is 53 mrem/min. Hand dosing is 58 mrem/min [10]. These dose rates are 10–12 times the radiation exposure for