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x ±
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Table18.7 Thickness (mm) ofthe gum andcortical plate inthe
mandibular vestibule.
SD 95% CI
Attached gingiva (Goaslind etal.1977)
Cortical bone First PM 1.8±0.3 1–2 (Denio etal.1992) Second PM 2.0±3.1 0–5
First M 2.7±0.5 2–4 Second M 3.2±0.7 2–5
CI, confidence interval; PM, premolar; M, molar; SD, standard deviation.
Intermediate
outer component
Figure18.9 X- Tip® with the perforator and guide sleeve. Note
how the perforator and guide sleeve are presented as a unit
with the protective cap (upper image).
Inner
component
Solid metal
needle Guide sleeve
1.22
± 0.4
0.5–2
CapCrown
X- Tip®
This system comprises four elements (X- Tip 2010) (Figure18.9):
Hollow metal guide measuring 0.63 × 7 mm (the
active part), which contains the perforator and which, once placed in the mouth, serves as a guide for the needle (Gallatin etal.2003b).
3) Protective cap (generally in a bright color, red) that cov-
ers the active part of the complex or perforator-
catheter­guide sleeve block. This set is presented together in a plastic ampoule inside a blister pack.
4) Extrashort 27G needle (0.4 × 9 mm), with measure-
ments identical to those of the perforator to be able to penetrate the guide sleeve.
Anesthetic Solutions
Clinical trials show that local anesthetic solutions with epi­nephrine yield better results than those that do not contain vasoconstrictor (Lilienthal and Reynolds1975b; Replogle et al. 1997) or those that contain felypressin (Lilienthal 1976). In addition, no statistically significant differences have been found between the use of solutions containing articaine 4% and lidocaine 2%, both of which contain epinephrine 1:100
000 (Bigby etal.2006).
Despite containing epinephrine, the anesthetic enters the bloodstream very quickly with this technique (Cannell and Cannon1976), although the vasoconstrictor attenuates the increase in plasma concentrations (Wood etal. 2005). This technique is therefore considered to be equivalent to an intravascular administration, with positive aspirations in 60–85% of cases (Peñarrocha etal.1996, 2012).
Finally, when epinephrine is contraindicated, we can use vasoconstrictor- free solutions, such as mepivacaine 3% (Reisman et al. 1997; Replogle etal.1999) and prilocaine 3% with felypressin 0.03 IU/ml (Lilienthal1976), although the results for these agents are somewhat poorer.
1) Perforator, which is formed by a plastic shank with vari-
ous parts:
Plastic shank that is introduced into the contra-
angled hand piece.
Intermediate outer component to hold the guide
sleeve (cup).
Solid metal 27G needle (0.4 × 9 mm) that comes out of
the center of the female component and is the active part that perforates the cortical plate.
2) Guide sleeve, which is composed of the following parts:
Plastic inner component, which fits into the outer
component of the perforator and has a mark at the top where the needle is introduced.
Crown, a plastic outer component surrounding the
inner component and marking the depth stop for perforation.
Anesthetized Area
The area anesthetized with the intraosseous technique is very well defined, as is the case in all supplementary techniques.
Tooth (pulp and periodontal ligament) on which the
technique is performed distally and frequently extended to the adjacent tooth mesially.
Vestibule and lingual area, both the fibromucosa (alveo-
lar mucosa, gum, and interdental papillae) and the bone and periosteum of the anesthetized tooth. It is important to remember that this technique is used in a very well­defined area.
In the mandibula, the lower lip is also anesthetized in
65% of cases (Table 18.8), as is the tongue on many occasions.
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Table18.8 Variables to be considered in the intraosseous technique with Stabident® and X- Tip®.
Study data Study variables
Reference System Sample size Tachycardia No attached gingiva Anesthesia lower lip
Lilienthal (1976) 9 55% Leonard (1995) Stabident® 89
0% Coggins etal. (1996) Stabident® 40 78% 8% 58% Dunbar etal. (1996) Stabident® 20–40 80% 5% — Replogle etal. (1997) Stabident® 42 7% 76% Reitz etal. (1998) Stabident® 38 68% 2.5% — Guglielmo etal. (1999) Stabident® 40 78% 7.5% — Replogle etal. (1999) Stabident® 42 67% — Gallatin etal. (2003a) Stabident® 41 85% 5% 100% Gallatin etal. (2003a) X­Nusstein etal. (2003) X-
Tip® 41 93% 94% Tip® 33 73%
Bigby etal. (2006) Stabident® 37 81%
Average 78.1% 5.8% 64%
Rounded average 80% 5% 65%
Values are shown as percentages. The percentage of anesthesia in the lower lip only applies to use of the technique in the mandible.
Intraosseous Technique
Rubber dams must be removed (Nusstein etal.2003).
This technique is not very painful as a primary technique
(Annex 23), although in practice it is not painful because it is used as a supplementary technique when all other approaches have failed and the adjacent tissues– but not the dental pulp – are therefore anesthetized. If this approach is used as the primary technique, then we advise the following:
The Stabident® or X- Tip® extrashort needle can be used.Injecting 0.2–0.6 ml in the area to be drilled
(Lilienthal1975a; Pearce 1976; Leonard1995; Dunbar etal.1996; Coggins etal. 1996; Replogle etal. 1997; Gallatin etal.2003a,2003b).
Waiting 1minute for the gum, periosteum, and corti-
cal plate to become anesthetized before perforating (Leonard1995; Peñarrocha etal.1996).
The best advice is to use a local anesthetic solution con-
taining epinephrine (if there are no contraindications), similar to the one we are already using in the area (remember the principle of not mixing two anesthetics at the one site). For example, if articaine 4% with epi­nephrine 1:100 000 (A- 100) is used in the maxilla in a buccal infiltration, then this same solution can be used; if mandibular block is performed with the standard solution of lidocaine 2% with epinephrine 1:100 000
(L- 100) and then reinforced with A- 100in buccal area, then the intraosseous technique should be continued with A- 100.
Advise the patient that he/she may experience
palpitations:
When solutions with epinephrine are used, 80% of
patients have an increased heart rate that is felt as palpi-
tations (Table18.8), which last 2–4minutes (Lilienthal and Reynolds 1975b); in 20% of cases, they may last 4–6 minutes (Replogle etal.1999; Guglielmo etal.1999).
No palpitations are observed with epinephrine- free
anesthetic solutions (Replogle et al. 1999; Guglielmo etal.1999). Similarly, palpitations do not appear if the injection rate is very slow (around 5 minutes) (Susi etal.2008). This is difficult to ensure manually, although it is easy with computer- controlled delivery systems.
Selection of the perforation site.Perforate distally to the tooth to be treated
(Leonard1995); however, perforation may be mesial in certain cases:
Second permanent molar because it is located
toward the back of the mouth.
Very crowded teeth because there is little cortical
bone between them.
Perforate buccally, with an equal distance between the
two teeth (Figure18.10).
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Cortical bone
a
C
2 mm Line
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Pulp
ancellous
bone
Attached gingiv
Figure18.10 Perforation via the buccal area at an equal
distance between the teeth. Source: Redrawn from Leonard (1995) and Reader etal. (2011).
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Figure18.11 In the Stabident® system, the dentist perforates
2
mm apically from the imaginary horizontal line that passes
through the gingival margin into the attached gingiva. Notice
how the horizontal line traverses the gingival margins of the
adjacent teeth and the vertical line bisects the interdental papilla.
Stabident® X- Tip®
At 2 mm toward the apical
part of the imaginary horizontal line that passes
through the gingival margin (Figure18.11).
Always on the attached
gingiva. If this is missing (5%, Table18.8), then at 1 mm above the mucogingiv aljunction.
aAlways on attached gingiva, since if the technique is performed on
the alveolar mucosa, which is mobile, there is movement above the perforation in the cortical plate and the placement of the insertion point is then very difficult (Bourke1974). Remember that the teeth where the attached gingiva is usually less narrow in the area of the canines and maxillary and mandibular first premolar (Bowers1963).
In edentulous areas, the perforation is made vertically,
a
on the alveolar crest, where the cortical layer is thin-
Identical to Stabident®,
although we can even go a further 3–7 mm toward the apex.
On attached gingiva or even
on the alveolar mucosa (Gallatin etal.2003a; Nusstein etal.2003) since this approach has a guide sleeve.
Figure18.12 Perforation is vertical in edentulous areas.
structures may be damaged (mental nerve, mandib­ular canal, etc.) or the intraosseous technique may fail because the needle does not penetrate the can­cellous bone (maxillary sinus).
Place the perforator in the contra- angle and proceed as
follows:
Stabident® X- Tip®
Remove the protective cap from the active part
When the protective cap is removed from the active part, hold the crown of the guide sleeve with one finger so that the guide sleeve does not come out of the perforator.
ner (Figure18.12).
Observations on the perforation point:
If the perforation is made in areas close to the papilla
(Stabident®), distant from the apex, the bone may be fragile and the intraosseous technique may fail.
If the perforation is made in very apical areas
(X- Tip®), where the cortical layer is very thick,
Perforate the cortical layer with the perforator placed at a
contra- angle, as follows:
Place the drill perpendicular to the area to be perfo-
rated without activating the handpiece.
Insert the drill by pushing it until the tip touches the
bone after crossing the gum or mucosa (Figure18.13).
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50−80°
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90°
Figure18.13 Approximate angle at which the perforator is inserted with Stabident® (note that it is in the attached gingiva) and
X- Tip® (note that, in this case, it is in the alveolar mucosa).
Stabident® X- Tip®
The angle over the vertical axis of the tooth varies:
Upper teeth 60–80°
Lower teeth 50–60°
The angle over the vertical axis of
the tooth will be 90°.
If the alveolar mucosa is involved,
it should be pulled taut with a finger of the other hand to
minimize the possibility that the perforator will become stuck in the mobile mucosa on activation and detach it.
The handpiece is activated at low speed
000–20 000 rpm):
(15
With irrigation to prevent overheating of the bone
and thus reduce postoperative pain.
With short, intermittent impulses, by applying a
slight pressure. When the perforator reaches the cancellous bone, we feel it “give” as the resistance of the cortical bone cedes (Schmitt1936; Bourke1974; Pearce1976). Sometimes, the patient feels a vibra­tion such as that felt during tartar removal (Peñarrocha etal.1997).
The maneuver lasts 2–5 seconds (Bourke 1974;
Dunbar etal. 1996; Coggins et al. 1996; Replogle etal.1997). If it takes more than 5seconds, the pro­cedure should be stopped and the area selected checked. The greater the hardness or thickness of the cortical layer, the longer it will take, for example in the posterior parts of the mandibula or when a dental root is perforated (serious problem).
Insert the extrashort needle.Hold the syringe with the needle in place with a pen
grip, with the fingers near the hub to help with inser­tion (Lilienthal1975a) (Figure18.14).
Stabident® X- Tip®
Remove perforator.
Identify the orifice of the
perforation. This is done by drying and blotting the area with gauze to clean up any blood and reveal the little blood spot on the inserted gingiva (Schmitt1936).
Insert the needle across
the perforation, in exactly the same direction as the perforation in order not to touch the walls of the orifice. This maneuver
After perforation, and with
the handpiece stopped, use tweezers to hold the crown surrounding the inner component of the sleeve guide
against the gum so that when the perforator is removed from the bone, it does not drag the guide sleeve and pull it out of the bone (Figure18.15).
Insert the needle across the
orifice in the cusp of the inner component of the guide sleeve (Figure18.16).
may prove difficult and have to be tried a few times
(Figure18.16).
The needle should be bent in posterior teeth:
Approximately 45° to facilitate insertion (Dunbar
etal.1996; Coggins etal.1996; Replogle etal.1997; Parente et al. 1998) and even 60–80° (Gallatin etal.2003a; Nusstein etal.2003).
Squeeze a few drops of anesthetic out of the tip of
the needle to ensure that bending the needle has not obstructed the lumen.
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50−80°
Figure18.14 Holding the syringe with a pen grip.
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Remember that inserting the needle at the level of
the second molar can prove difficult owing to the lack of accuracy and of angulation (Leonard1995).
Slow injection of half a cartridge (0.9 ml) in 30 seconds
(Lilienthal and Reynolds1975b) or even more slowly up to 2
minutes (Pereira etal.2013), and a whole cartridge
(1.8
ml) in 1–2 minutes. The most common approach is to inject the whole cartridge (Coggins et al. 1996; Reisman etal.1997; Replogle etal.1997,1999; Guglielmo etal.1999; Gallatin etal.2003a).
Inject slowly since the solution enters the bloodstream
very quickly (Cannell and Cannon 1976; Wood etal.2005).
Little resistance is noted on injecting since the solution
is entering the cancellous bone.
When the injection finishes, the needle should be
pressed for a few seconds to prevent reflux and enable the anesthetic to spread and reach the apexes (Pearce1976).
The needle is not aspirated: we know that aspiration is
positive in 60–85% of cases because it is inevitably intravascular (Peñarrocha etal.1996, 2012).
Withdraw the needle.
Figure18.15 In the X- Tip® system, when the perforator is
withdrawn after perforation, the crown (marked with an arrow)
should be held so that the guide sleeve remains inserted in the gingiva and bone.
Stabident® X- Tip®
Withdrawal of the needle leaves a blood spot on the gum.
Withdraw the needle from the
guide sleeve.
Then, withdraw the guide
sleeve from the bone with a hemostat or pliers.
Note (X- Tip®): Before withdrawing the guide sleeve,
ensure that the tooth is anesthetized in order to be able to reinject if necessary, without having to start over.
Figure18.16 Insert the needle for injection.
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Pulpal anesthesia takes effect quickly (Leonard 1995;
Parente et al.1998; Peñarrocha et al.1996), generally in about 2
minutes (Gallatin etal.2003a; Nusstein etal.2005b;
Pereira etal. 2013), and lasts about 25
minutes (Nusstein
etal.2005b).
If the tooth remains sensitive after 2 minutes, we can
reinject (Magnes 1968; Reisman et al.1997; Parente etal.1998).
Anesthesia is restricted to the tooth and adjacent teeth,
therefore the patient generally experiences few symp­toms in the soft tissues. If this approach is used only as the primary technique, the soft tissue anesthesia can last 25–30
When an intraosseous injection has been performed in
minutes (Lilienthal1976).
the mandibula, the lower lip is affected by soft tissue anesthesia in 65% of cases (Table18.8).
Efficacy
The efficacy of this technique evaluated using electrical pulp testing shows that it is successful in 95% of cases in maxillary teeth and in 85% of cases in mandibular teeth (anterior and posterior) (Table18.9); the effect of pulpal anesthesia lasts for around 25 minutes (Nusstein etal.2005b). Evaluation of clin­ical success (more subjective and less rigorous) reveals a suc­cess rate of around 95%, although this may be with one or two injections (two if the first one fails) (Magnes 1968; Pearce1976).
Specific Complications
Complications Dueto Mechanical Aspects
1) Pain during perforation of the cortical plate in approxi-
mately 10% of cases (Annex 23). This may be due to the following:
Inappropriate anesthesia of the gum, alveolar
mucosa, and periosteum. This can be improved by increasing infiltrative anesthesia.
Teeth with irreversible acute pulpitis. In such cases,
the tissues are very sensitive despite the infiltrative anesthesia and anesthesia of the soft tissues. In some series, moderate-
to- intense pain is recorded in around
50% of cases (Nusstein etal.2003).
Perforation of the periodontal ligament or lamina
dura of any of the adjacent teeth. In these cases, we must remove the drill and modify the angle of perfo­ration or search for an alternative interdental space mesially or distally.
2) Not perforating the cortical plate in less than 5 seconds
and not feeling that the perforator has reached the can­cellous bone. This may be caused by the following:
Lack of cancellous bone because the teeth are close
together. The solution is to move the perforation point mesially or distally.
The root of an adjacent tooth is being perforated
(Coggins et al. 1996; Dunbar et al. 1996; Replogle etal.1997). In terms of touch, a difference can be felt
Table18.9 Percentage ofpulpal anesthesia, evaluated using anelectric pulp tester after theintraosseous technique
withstandard lidocaine 2% withepinephrine 1:100 000 solution (L- 100) and in mesial and distal tooth.
Anesthesia
Pulpal
Tooth Reference Sample size
Maxillary arch
First M Coggins etal. (1996) 40 93% 68% 93% LI Coggins etal. (1996) 40 90% 73% 88%
Nusstein etal. (2005b) 40 98%
Average 93.6% 70% 90%
Rounded average 95%
Mandibular arch
First M Coggins etal. (1996) 40 75% 52% 90%
Replogle etal. (1997) 42 74% 57% 76% Gallatin etal. (2003a) 41 93% 81% 95% “ 93% 83% 95%
LI Coggins etal. (1996) 40 78% 52% 58%
Average 82.6% 65% 83%
Rounded average 85%
First M, first molar; LI, lateral incisor.
anesthesia
Mesial Distal
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between the bone and the root, and it takes consider­able strength to perforate the root (Coggins etal.1996). The solution in these cases is to reorient the perforation or change the perforation site.
Cortical layer excessively thick (>8 mm). This situa-
tion arises in 2.5% of cases (Table18.7), although it has arisen in 8% of cases in some series (Peñarrocha etal.1996). In these situations, the direction of the perforation can be changed or, if this does not work, an alternative technique, such as the PDL injection, can be applied. Remember that with Stabident®, the angle of perforation may be excessively open or closed, with the result that the cortical layer becomes thicker.
3) Excessive pressure is needed to inject the anesthetic
solution. This situation may arise in 10% of cases (Table18.10) because of the lack of cancellous bone, obstruction of a bent needle, or insufficient perforation of the cortical layer (Lilienthal1975a). The measures to be taken are as follows (Gallatin etal.2003a):
Rotate the needle a quarter turn to inject via a differ-
ent part of the bevel, where there may be cancellous bone or the cortical plate has been perforated.
If this does not work, remove the needle and verify
that it is not obstructed. This situation is more com­mon with bent needles.
If the all of the above fail, start again.
4) Specific complications of the Stabident® system:
Breakage of the perforator with separation of the
metal needle from the plastic shank (2% of cases) (Table18.10). In this case, the needle can be removed easily with pliers or a hemostat (Coggins etal.1996; Replogle et al. 1997; Parente etal.1998). This situa­tion is now uncommon because of improvements in the materials used.
Inability to locate the perforation site to insert the
needle in 8% of patients (Table18.10). This may arise for two reasons:
1) The alveolar mucosa has been perforated instead
of the attached gingiva, with the result that the soft tissues move above the perforation in the cor­tical plate, thus making the insertion site difficult to locate. If the site is not located after several attempts, the only solution is to make a second perforation, only this time in the attached gingiva.
2) The needle is not inserted into the perforation at
the same angle, therefore it makes contact with the lateral walls and does not cross the cancellous bone. This situation is common in mandibular molars (Replogle etal.1997). The solution is one of trial and error, in which the dentist attempts to redirect the needle. In the case of posterior teeth, it could prove useful to bend the needle to reach the
opening more easily. If these approaches fail, we can start again with a fresh perforation.
5) Specific complications of the X- Tip® system:
There are two reports of breakage of the guide sleeve,
which separated from the metal cannula of the plastic inner component (Gallatin et al. 2003a; Pereira etal.2013). The solution is to withdraw the metal part with a hemostat or pliers, given that it projects by 3
mm. The procedure should be restarted or the open­ing should be used as if we were working with the Stabident® system.
As the openings are larger, reflux of anesthetic solu-
tion via the guide sleeve is observed in approximately 10% of cases (Gallatin et al. 2003a; Nusstein etal.2003). This can be avoided by pressing the nee­dle in the top part of the inner component of the guide sleeve for a few seconds after the injection to enable the solution to spread through the cancellous bone without reflux.
Note: When the perforation is repeated close to the initial site as a result of a problem, there is some reflux of the anesthetic solution through the first opening (Peñarrocha etal.1996).
Postoperative Complications
Postoperative complications are caused by injury to tissue resulting from drilling and the maneuvers applied in this technique. However, they are not associated with the anes­thetic solutions used (Replogle etal.1997).
1) Moderate to severe pain at the perforation site in 10% of
cases (Table18.10). This usually disappears spontane­ously in 1–3 days (Peñarrocha et al. 1996; Gallatin etal.2003b).
2) The tooth feels high during occlusion in around 10% of
cases (Table18.10) owing to damage to the periodontal ligament and inflammation of the bone. This disap­pears spontaneously in 1–3
days (Replogle etal. 1997;
Gallatin etal.2003b). Occlusion can always be adjusted.
3) Injection site lesions in 5% of cases (Table18.10) with
inflammation, reddening, pain, and even purulent exu­date, which may require treatment with antibiotics, dis­infectant solution, and analgesics (Coggins etal.1996; Peñarrocha etal.1996; Replogle etal.1997). This may last up to 14 days (Coggins et al. 1996; Replogle etal.1997). In addition, these lesions are thought to be caused by overheating of the bone and pressure during drilling. Hematomas have also been reported (Dunbar et al. 1996), as have aphthous ulcers (Replogle etal.1997), which resolve spontaneously in a few days.
4) Osteonecrosis. There is one report of osteonecrosis that
resulted in extraction of the two mandibular molars in an HIV- infected patient who was taking antiretroviral
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Table18.10 Percentage ofcomplications ofthe intraosseous technique during theprocedure andafterwards.
Study data Complications during technique Complications after surgery
Excessive
Reference System Sample size
Leonard (1995) Stabident® 89 11% 4% — Coggins etal. (1996) Stabident® 40–160 9% 0.6% 2–15% 4% 3% Dunbar etal. (1996) Stabident® 40 15% — Peñarrocha etal. (1996) Stabident® 50 — Replogle etal. (1997) Stabident® 44–84 19% 4% 10% 2–10% 13% 5% Parente etal. (1998) Stabident® 37 — Reitz etal. (1998) Stabident® 38 11% 0% 0% Guglielmo etal. (1999) Stabident® 80 — Gallatin etal. (2003a) and
Gallatin etal. (2003b) Gallatin etal. (2003b) X- Tip® 41 2.5% 2.5% 25% 15% 22% Nusstein etal. (2003) X­Peñarrocha- Oltra etal.
(2012) Pereira etal. (2013) X- Tip® 60 1.5% 1.5%
Stabident® 41 12% 0%
Tip® 33 18% 0%
Stabident® 100 6% 6% 11%
Average 12.4% 2.2% 7.5% 11% 8% 4.9% Rounded average 10% 2% 8% 10% 10% 5%
pressure
10% 24% 2%
3%
10–13% 9% 3%
Perforator breakage
2% 10% 3%
Failure to locate perforation Severe pain High teeth
7% 5% 5%
Local lesions
drugs. In this case, the X- Tip® system was used by a young, inexperienced dentist who may have applied the technique without irrigation. These factors may have contributed to the accident (Woodmansey etal.2009).
Final note: The intraosseous technique has fewer adverse
effects than the PDL injection.
Pulpal Abnormalities
Pulpal abnormalities have not been detected in humans in clinical studies to date (Dunbar et al. 1996; Replogle etal.1997; Reitz etal.1998; Guglielmo etal.1999; Gallatin etal.2003b).
Final Remarks
When performed with pressure, the intrapulpal technique is 100% effective (see above). However, in endodontic treat­ments, it is often necessary to reach the pulp (this may be impossible because of the pain in acute pulpitis) and the technique is of no use in nonpulpal treatments (e.g. cutting
or a very deep cavity). In these cases, we can use the PDL injection and intraosseous technique, both of which require special equipment and have advantages and disad­vantages, as follows:
Advantages of the intraosseous technique over the PDL
injection:
Greater pulpal anesthesia in the first injection (85% vs.
65% in acute pulpitis [Annex 35]).
Greater duration of pulpal anesthesia (25 minutes vs.
10
minutes).
Fewer postoperative adverse events.
Disadvantages of the intraosseous technique with respect
to PDL injection:
Later onset of pulpal anesthesia (2 minutes vs. 30 sec-
onds), although this is of little clinical relevance.
The rubber dam has to be removed during endodontic
treatments.
In central incisors (upper and lower) with little can-
cellous bone, it is not possible to use the intraosse­ous technique, therefore the PDL injection must be used.
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