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Mandibular Anesthesia I: Pulpal Anesthesia
281
Mandibular block is the technique of choice for pulpal
anesthesia of the mandibular molars and premolars.
Infiltration is much less effective when applied to the mandible, owing to the higher density of the cortical bone in the
mandible as compared to the maxilla (Table3.2, Chapter3),
especially along the external oblique ridge. Mandibular
block accounts for nearly 30% of all anesthetic injections
performed in dentistry (Annex 1). Although it also known
as inferior alveolar nerve block, the term mandibular block
is more semantically precise because the block often
involves not only the inferior alveolar but also the lingual
and buccal nerves, and the nerve to the mylohyoid muscle.
Mental nerve block has been excluded from this chapter
because of its two disadvantages:
1) The mental foramen is difficult to locate. In clinical
practice, it takes a full minute or longer to find when
sought with a needle between the apexes of the two premolars in over 40% of cases (Joyce and Donnelly1993).
2) The risk of introducing the needle to the mental fora-
men and injuring the vascular nervous package is high.
Clinical studies have shown that there is a 23% risk of
hitting (Lustig and Zusman 1999) and a 12% risk of
damaging the mental nerve (Joyce and Donnelly1993).
Buccal infiltration with potent a local anesthetic such as
4% articaine with 1:100 000 epinephrine (A- 100) is a
technique more readily mastered that yields good
results and entails lower risk.
Indirect mandibular block or the 1- 2- 3 technique, developed by Heinrich Braun (Lindsay1929a) and furthered by
Guido Fischer since 1910 (Fischer1910), has likewise been
excluded. Known by that name because it consists of a
three- phase attempt to reach the groove of the mandibular
neck (sulcus colli) indirectly by varying the direction of the
needle in the soft tissue (Figure16.1), the technique calls
for very thick, stiff caliber 20G needles (no longer in use)
that neither break nor bend. It is characterized by major
disadvantages, including needle breakage, increased technique sensitivity, and higher probability of injuring the
periosteum or the medial (internal) pterygoid muscle
(Lindsay1929b). Although there are more modern variations (Clarke and Holmes 1959; Sittitavornwong
et al. 2017), the 1- 2- 3 technique is of primarily historic
interest and is seldom used today.
All the techniques listed below and described in this
chapter are intraoral because extraoral approaches are
mostly confined to hospital scenarios.
● Mandibular block for pulpal anesthesia of molars and
premolars via the:
○ conventional or direct approach
○ Gow- Gates approach
○ Laguardia–Akinosi approach
● Double infiltration for pulpal anesthesia of the anterior
mandibular teeth.
Mandibular Block: General Remarks
The first known mandibular block was performed by
William Stewart Halsted on a medical student in 1884, who
was administered 0.4
(Hall1884). There is no record of whether the technique
was intra-
or extraoral, although the three techniques most
commonly used today are intraoral.
The primary but not the sole aim of all these techniques
is to introduce enough solution to anesthetize the inferior
alveolar nerve before it enters the mandibular foramen
(Berns and Sadove 1962; Galbreath and Eklund 1970).
Given that the inferior alveolar nerve fibers are myelinated,
at least three nodes of Ranvier (Blair and Erlanger1939) or
a total of 6 mm must be anesthetized since the nodes in this
nerve are spaced at 0.5–1.8 mm (Rood1978a,b).
ml of a 4% solution of cocaine
Local Anesthesia in Dentistry: A Locoregional Approach, First Edition. Jesús Calatayud and Mana Saraghi.
© 2024 John Wiley & Sons Ltd. Published 2024 by John Wiley & Sons Ltd.
Companion website: www.wiley.com/go/Calatayud/local
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2
Figure16.1 Mandibular block, 1- 2- 3 technique. Source: Redrawn from Andlaw and Rock (1994).
1
Zone Anesthetized
The various mandibular block techniques anesthetize the
following nerve trunks, although to varying degrees.
● The following areas are anesthetized by the inferior alve-
olar nerve (all in same side, ipsilateral):
○ Teeth, pulp, and periodontal ligament in the entire
hemiarch on the respective side; molars and second
premolar (via the inferior alveolar nerve itself) and
first premolar, canine, and incisors via the incisive
nerve, a branch of the inferior alveolar nerve.
○ Interdental papillae, including fibromucosa, bone,
and periosteum to the midline.
○ Vestibule, via the mental nerve; fibromucosa (alveolar
mucosa and attached gingiva), bone, and periosteum
in the area between the premolars and the central
incisor, including the molar zone in the 10% of cases
where the buccal nerve is scantly developed (Hendy
and Robinson1994); the skin over the ipsilateral half
of the chin and in particular half of the lower lip, from
the corner of the mouth to the midline, denoting successful anesthetization of the alveolar nerve.
● The lingual nerve affects the lingual side fibromucosa
(alveolar mucosa and gum), bone, and periosteum of the
teeth, along with half of the floor of the mouth and the
front two- thirds of the tongue on the side involved.
● The buccal nerve inneravates the following structures (all
ipsilaterally): the buccal fibromucosa (alveolar mucosa
and attached gingiva), bone, and periosteum of the retromolar triangle; side of the lower molars (reaching the second premolar in 5%) (Hendy and Robinson1994).
● Other nerves proximal to the inferior alveolar nerve may
also be anesthetized:
○ The auriculotemporal nerve, innervating the skin in the
temporal region, in some cases as far as the border of the
parietal, masseteric, frontal, and supraorbital regions. This
nerve is only anesthetized in 20% of cases due to migration
of the anesthetic, the odds of which are increased if the
patient is in a reclined position (Kim etal.2003).
○ The mylohyoid nerve, primarily a motor nerve and
branch of the mandibular division of the trigeminal
nerve, is located on the floor of the mouth. It also
innervates the anterior belly of the digastric muscle;
when anesthetized, the patient may feel discomfort
during swallowing. The nerve to mylohyoid may provide supplemental innervation to the pulp of the posterior and anterior teeth on the side in question and
even the contralateral incisors (Chapter3), as well as
sensory innervation to the skin on the chin (Roberts
and Harris 1973).This nerve trunk is frequently
anesthetized in mandibular blocks.
Factors toConsider forthe Mandibular Block
The factors that affect the scope and limitation of the mandibular block are discussed in this section.
Efficacy is Correlated tothe Location ofTooth
inthe Mandible
Mandibular block delivers acceptable results in molars and
premolars (Table16.1). Pulpal anesthesia is successful in
60–70% of cases involving the posterior teeth within
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Table16.1 Degree (%) ofpulpal anesthesia inlower teeth 10 and15 minutes after injecting one (1.8 ml) or two (3.6 ml)
cartridgesofa standard Leffect electric pulp tester data (see Annex 25).
Tooth
Posterior (M and PM) 60% 65% 80%/40 min 65% 70% 80%/40 min
Lateral incisor 30% 35% 55%/40
Central incisor 10% 15% 25%/30
M, molar; PM, premolar.
10–15 minutes after injection of 1.8 or 3.6 ml of standard
solution (2% lidocaine with 1:100
In contrast, as the results are poor in the anterior teeth
100 solution forconventional mandibular block, aswell asmaximum success rate (%) andtime ofpeak
1.8 ml 3.6 ml
Time after injection
000 epinephrine, L- 100).
Maximum success
min 30% 40% 55%/40 min
min 15% 25% 35%/40 min
waiting 40
same applies to the soft tissue anesthesia peaking in the
Time after injection
Maximum success10 min 15 min 10 min 15 min
minutes is not normally practical today. The
lower lip after 40 minutes (Hersh etal.1995).
(Table16.1), mandibular block can be said to be effective in
posterior mandibular teeth only.
High Failure Rate
As mandibular block is characterized by a high failure
rate even in posterior teeth, it must be reinforced, as discussed later.
Unreliability ofLower Lip Anesthesia
An anesthetized lower lip is indicative of anesthesia of the
mental nerve which innervates it but not of mandibular
dental pulp (Annex 25). A numb lower lip is specific but
not sensitive: its absence definitely indicates that the pulps
are not anesthetized, but its presence is not a reliable indicator that the pulps are anesthetized (Chavarria- Bolaños
etal.2017). In other words, a numbed lower lip is a necessary but not a sufficient indication of pulpal anesthesia.
Sequential Nature
The lower lip and teeth are anesthetized sequentially. The
lower lip is anesthetized first, followed by pulpal anesthesia of the molars, premolars, and anterior teeth in that
order (Table16.2). The conclusion is that anesthetic onset
is longer than previously thought. Clinicians should wait at
least 10–15 minutes after administering the anesthetic,
which is when pulpal anesthetic onset is most rapid. After
that time, anesthetic onset continues but much more
slowly (Annex 25).
The Longer theTime, theMore Intense
theAnesthesia
In 80% of cases, maximum pulpal anesthesia in posterior
teeth is attained after 40 minutes (Table 16.1), although
Minor Effect ofthe Type ofAnesthetic
In mandibular block, the different local anesthetics available have little impact on success and all are effective (Annex
24). A mandibular block is effective if the anesthetic is
injected close to the inferior alveolar nerve, spanning the
lingula and a few aponeurotic membranes, to position the
solution in a place from which it can spread passively
toward the nerve essentially unobstructed. That is not the
case in buccal infiltrations, in which the potency of the
anesthetic is instrumental to efficacy because the solution
must cross barriers (periosteum, cortical, and spongy bone)
to reach the dental apex and anesthetize the pulp. In mandibular blocks, other factors such as accessory pulpal
innervation (mylohyoid nerve, buccal nerve), anatomical
variations (high lingula, double alveolar ducts), and the
greater complexity of the technique affect the outcome,
inducing failed pulp anesthesia even when the inferior
alveolar nerve is successfully blocked (deeply numbed
lower lip).
The anesthetic of choice for mandibular blocks is 2%
lidocaine solution with 1:100 000 or 1:80 000 (L- 100 or L- 80)
for the following reasons:
● It is just as effective as even the most potent solutions (with
high anesthetic or vasoconstrictor concentrations) such as
4% articaine with 1:100 000 epinephrine (A- 100) or 2%
lidocaine with 1:50 000 epinephrine (L- 50) (Annex 24).
● Lidocaine is less concentrated, which means that more
volume can be administered before reaching the maxi-
mum recommended dose (MRD). In more concentrated
local anesthetics, such as 3% mepivacaine or 4% artic-
aine, the MRD is achieved at a lower volume. For patients
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Table16.2 Reported and mean electric pulp tester- measured times (minutes) of lower lip and pulpal anesthesia in first molar
(first M), first premolar (first PM) and lateral incisor (LI).
Lower lip
Reference Sample size
Vreeland etal. (1989) 30 8.8 6.2 8.4 — 13.2
Chaney etal. (1991) 30 4.7 7.7 8.2 10.2 13.0
Hinkley etal. (1991) 30 6.1 10.6 8.8 10.6 12.3
McLean etal. (1993) 30 5.0 10.7 10.8 11.8 17.8
Kanaa etal. (2006) 38 —
Steinkruger etal. (2006) 51 —
Steinkruger etal. (2006) 51 —
Goldberg etal. (2008) 40 —
Kanaa etal. (2009) 36 —
Mean 6.2 8.8 8.3 9.9 13.6
weighing at least 70 kg, up to 8.5 cartridges (1.8 ml) of 2%
lidocaine can be administered as the maximum dose
(Annex 10), whereas with other solutions only 5.5 to
seven cartridges can be injected. This is especially important when treating small children, as local anesthetic
overdose and toxicity is more of a concern.
● It has been listed by the US FDA as pregnancy risk
B (safe).
● There is less risk for neurotoxic injury to the inferior
alveolar nerves when applied as a block. This is not a
property that is inherent to lidocaine, but rather due to
the lower lidocaine concentration (2%), as compared to
4% solutions of articaine and/or prilocaine, which has
been implicated in such side effects (see Chapter22).
— 5.4 8.9 13.3
— 8.8 10.8 13.0
— 9.2 10.8 13.0
— 8.0 7.0 12.0
— 6.8 8.9 10.9
anesthesia is necessary. This procedure was initially
believed to entail the risk of serious consequences, such as
soft tissue (tongue and lip) injury due to inadvertent biting
or discomfort for patients (i.e. dysgeusia, dysphagia as the
tongue is anesthetized.) Nonetheless, the only problem
reported to date is minor discomfort when swallowing or
drinking (Adatia and Gehring 1972). Even in children,
bilateral mandibular block has been found (antito lead to less selftwo reasons: (i) as bilateral blocks entail more extensive,
lengthier treatment, the child’s soft tissues are anesthetized
for less time after leaving the dentist’s office and (ii) as the
soft tissue anesthesia is felt symmetrically, children are less
inclined to explore and bite the tongue and cheeks, as they
First M First PM LISubjective Objective
intuitively)
injury than its unilateral counterpart for
do not feel a contrast in sensation between the two sides
Impact ofthe Volume Injected
(College etal.2000).
As Table16.1 shows, injecting two cartridges of the standard solution (3.6 ml of L- 100) improves pulpal anesthesia
after 10–15 minutes in 5% of posterior teeth (Annex 25).
Long, Caliber 25G Needles
Mandibular block should be performed using caliber 25G
needles (a slightly less optimal alternative is caliber 27G, in
Minor Effect ofthe Specific Mandibular
Block Technique
The Gow- Gates technique was initially believed to deliver
better results than the conventional or direct technique,
but as discussed throughout this chapter that has not been
proven. Overall, the conventional or direct technique
affords the best clinical results of the three mandibular
block approaches (Table16.3) and is the easiest to master.
as much as 25G needles are not readily available today) for
the following reasons (see Chapter11):
● They deviate less across the linear insertion.
● They ensure good aspiration.
● They do not cause more pain (pain myth, Chapters 11
and13).
● They are less likely to break.
The 25G needle must be of sufficient length to traverse
Bilateral Mandibular Blocks
Bilateral mandibular blocks (on the right and left sides
simultaneously) can be utilized when bilateral mandibular
20–30 mm of soft tissue before reaching the target and
should never be inserted into the soft tissue up to the hub
because they are more liable to break.
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Table16.3 Comparison ofconventional, Gow- Gates, andLaguardia–Akinosi mandibular block techniques:
clinical variables.
Mandibular block technique
Laguardia–
Variable
% Positive aspirations 10% 5–10% 5% Annex 22
% Lower lip failure
min
After 5
After 10
min
% Lingual nerve anesthesia 95% 80% 85% Annex 29
% Buccal nerve anesthesia 60% 70% 70% Annex 29
Grade A anesthetic efficacy 85% 80% 80% Annex 30
10%
5%
30%
5%
Akinosi
30%
20%
ReferenceConventional Gow- Gates
Annex 28
Slow Injection
As noted in Chapter13, the injection speed presently recommended is 40–60
● Reduce pain because tissues are not distended abruptly.
● Reduce toxicity in the event of intravascular injection.
seconds for a 1.8- ml cartridge to:
ure for preventing adverse reactions, more even than
aspiration (Malamed2004).
● Enhance clinical efficacy. Higher pulpal anesthesia suc-
cess rates according to clinical trials (Kanaa etal.2006).
Mandibular Block: Conventional
orDirect Technique
The conventional or direct technique, also denominated
the classic or standard (or inferior alveolar nerve block), is
much more commonly used than others worldwide
because of its greater efficacy and relative simplicity. It
consists of inserting the needle, directed from the lower
premolars on the opposite side, into the pterygotemporal
depression and subsequently into the pterygomandibular
space (Figure3.14, Chapter3) and from there to the sulcus
colli in the ramus of the mandible above the lingula
(Figure 16.2), where the anesthetic solution is deposited
and where the inferior alveolar nerve lies in a wide open
mouth. It is called “direct” because the needle is inserted
directly to the target, with no need for prior maneuvering.
This technique was initially introduced by Parisian clinician Pageix in 1906, although he directed the needle from a
point on the midline too high (15–20
plane (Lindsay1929a). Boris Levitt (NewYork) developed
the technique as it is known today (Levitt 1924), while
Ashley Lindsay (Toronto) was instrumental in its popularization (Lindsay 1929a,b). Nonetheless, a host of minor
mm) over the occlusal
Figure16.2 Sulcus colli above and behind the lingula, where
the anesthetic solution is deposited in conventional
mandibular block.
variations on the technique are in place and each dentist
could almost be said to have their own.
Distribution ofthe Anesthetic Solution
The anesthetic solution normally spreads rapidly across
the pterygomandibular space and it remains there for several minutes (Petersen 1971). It is confined between the
anterior and posterior edges of the ramus of the mandible,
although the course taken cannot be predicted because the
path of least resistance is determined by the fascial planes
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and the structures inside the pterygomandibular space
(Berns and Sadove1962; Galbreath and Eklund1970). That
said, it tends to travel upward and backward (sigmoid distribution) (Berns and Sadove 1962; Galbreath and
Eklund1970; Petersen1971), therefore the success rate is
lower if the anesthetic is positioned too high and too far
back of the inferior alveolar nerve (Galbreath and
Eklund1970; Petersen1971). In such situations, while the
solution tends to spread to the parapharyngeal space, it
does so more slowly (Petersen1971).
The greatest factor in achieving a successful direct mandibular block is the position of the needle, which must be
as close as possible to the beginning of the mandibular
foramen and behind and close to the lingula (<5 mm), but
this does not guarantee a perfect success rate (Berns and
Sadove 1962; Galbreath and Eklund 1970). In contrast,
placing the tip of the needle more than 5
mm away from
and behind the mandibular foramen is associated with a
large number of failures (Berns and Sadove1962; Galbreath
and Eklund1970; Petersen1971).
Zone Anesthetized
The zone anesthetized is as described in the general
remarks, although the degree to which each element is
numbed varies from one technique to another. All techniques must anesthetize the inferior alveolar nerve, often
indicated by soft tissue (the lower lip ipsilateral to the
injection site). In 95% of cases, the lingual nerve is also anes-
thetized with this technique and the buccal nerve in 60%
(Table16.3 and Annex 29).
Technique
● Use a long (35–42 mm) needle, given the depth of the
insertion. Caliber 25G is ideal because it affords good aspiration and as it is thick and stiff, it deviates very little. If
caliber 25G is not available, 27G can be used, although this
is less effective because deflection is somewhat greater.
● Solution. In most cases standard 2% lidocaine with
000 (L- 100) or 1:80 000 (L- 80) epinephrine is the
1:100
option of choice (Annex 24).
● Patient positioning
○ Supine or semisupine in dentist’s chair.
○ Mouth opened maximally throughout the injection to
facilitate direct visualization of intraoral landmarks
and ensure that the inferior alveolar nerve lies against
the sulcus colli on the inner side of the ramus of the
mandible (target area).
○ Head turned slightly to the same side as the side being
injected (i.e. right in rightleft-
side blocks).
○ Tongue at rest and low in the posterior part of the
side blocks and to the left in
mouth (Keetley and Moles2001).
● Dentist’s position and position of the non- dominant
hand (i.e. left hand in right-
handed clinicians), depend-
ing on the side to be anesthetized
○ Right side:
○ Dentist at 8:00 o’clock.
○ Index finger in the patient’s mouth (Figure16.3).
○ All other fingers stretching across the patient’s face
to block their vision and control the position of
the mouth.
Figure16.3 Index figure of non- injection hand inside patient’s mouth for approach from right side, with other fingers stretched
across patient’s face.
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○ Dentist at 9:00–10:00 o’clock.
○ Thumb of the non- dominant hand in the patient’s
mouth, requiring the right-
handed dentist to pass
their left arm over the patient’s forehead (Figure16.4).
○ Dentist’s non- injection palm and wrist blocking
patient’s vision.
● Intraoral finger or thumb. The finger in the patient’s
mouth should rest on the anterior edge of the ramus of the
mandible, in the concavity known as the coronoid notch
(Figure16.5). It should also be parallel to the occlusal
plane of the mandibular molars to:
○ Bring the pterygotemporal depression into view.
○ Help visualize the zone and locate the needle inser-
tion site.
○ Tighten and stretch the soft tissue to make needle
insertion less traumatic.
In 10% of cases the coronoid notch cannot be readily
reached because it is underdeveloped or the adjacent soft
tissue is very thick (anterior edge of the temporal muscle
or adipose tissue and mucosa) (Angelman 1945). In such
cases, clinicians should gently exert greater pressure to
palpate the area and identify the anatomic landmarks.
● Insertion zone. The insertion zone lies in the ptery-
gotemporal depression, which consists of a fold or cleft
in the oral mucosa that is elliptical and elongated in
shape and runs parallel and outside to the pterygomandibular raphe or ligament (medial limit) (Figure 16.6)
(Khoury etal.2011). Its lateral limit is the deep tendon
287
ronoid
notch
Figure16.5 Intraoral index finger or thumb resting on
the anterior edge of the mandible in the hollow of the
coronoid notch. Source: Redrawn from Evers and
Haegerstam (1981).
Tempora
crest
Figure16.4 Thumb of non- injection hand inside patient’s mouth for approach from left side, with dentist’s palm and wrist blocking
patient’s vision.
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distinguish (Lindsay1929b). In such cases, the tip of the
intraoral finger should stretch the proximal buccal
mucosa and insert the needle outside the pterygomandibular ligament (always present), in the area where the
vertex of the pterygotemporal depression is assumed to
Pterygotemporal
depression
Area of coronoid
notch
lie (Lindsay1929b).
● Injection height.
○ A site around 10 mm above the occlusal plane of the
mandibular molars is recommended because in
95–100% of cases this ensures by-
passing the lingula
(Table3.7, Chapter 3), leaving the path to the sulcus
erygomandibular
ligament
colli clear.
○ The exception is the occlusal plane of the third molar
(wisdom tooth), unless it is aligned with the other two
molars (Bremer1952). The occlusal plane of the premolars can also be used as a reference if the molars are
Figure16.6 Pterygotemporal depression outward of the
pterygomandibular ligament or raphe.
missing.
○ One aid to finding the insertion height is, as noted ear-
lier, to draw an imaginary line backwards down the
middle of the finger on the non- injection hand (that
rests on the coronoid notch) toward the pterygotemporal depression (Figure16.7) (Angelman1945).
● Modification of the injection height.
○ It should be higher (>10 mm) in:
■ Toothless patients, for as the alveolar ridge is reab-
erygomandibular
ligament
sorbed, the lingula is higher.
■ Patients with a wide gonial angle and wide ramus of
the mandible, typical of class III Angle’s malocclusion
Pterygotemporal
depression
with mandibular hyperplasia (Hetson etal.1988).
○ It should be lower (<10 mm) in:
■ Children under 10 years and especially children
under 6
years (Benham1976) (Table3.8, Chapter3)
(Figure16.8).
■ Patients with a narrow gonial angle and ramus of
the mandible, typical of class II Angle’s malocclusion with mandibular hypoplasia (Hetson etal.1988).
Figure16.7 Needle insertion site in conventional technique
outside the pterygomandibular ligament, in the pterygotemporal
depression, around 10 mm over the occlusal plane of the
mandibular molars, with imaginary line projected distally from
mid- finger to help find the insertion site.
○ Some clarifications are in order regarding modifica-
tion in height.
■ In patients with a wide gonial angle and narrow
ramus of the mandible or vice versa, the needle
insertion height should be 10 mm.
■ Between its posterior and anterior the ramus of the
that attaches the temporal muscle to the temporal crest,
exactly where the finger is rested on the coronoid notch
(Figure3.14, Chapter 3) and thus highlights the ptery-
gotemporal depression.
Some clinicians draw an imaginary line along the mid-
dle of the intraoral finger, parallel to the occlusal plane,
and project it distally to pinpoint the insertion site
(Figure16.7).
In children under the age of 7 years (Via1953) and in
35% of adults (Angelman 1945) this depression and its
vertex lie under a mucosal pad and are difficult to
mandible is 30 mm wide on average, ranging from
20 to 40 mm (Table3.6, Chapter3).
■ The gonial angle is 120° on average, but may range
from 93° to 143°.
● Syringe direction.
○ In around 90% of cases the syringe is positioned over the
mandibular premolar zone on the opposite side, with
the needle traveling toward the pterygotemporal
depression and touching bone at the sulcus colli.
○ The divergent angle between the ramus of the mandi-
ble and the sagittal or medial plane is 0–27°
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27° angle
(b)
Figure16.8 Height of lingula relative to occlusal plane in
year- old child, (b) 8- year- old child, and (c) adult.
(a) 4-
(Figure3.11, Chapter3). In the nearly 10% of cases
where it is greater than 18° (Simon and Kömives1938),
the syringe must be positioned further back to reach
the sulcus colli, alongside the mandibular molars, for
with such a wide angle, if it lies above the premolars
the needle would run behind the ramus of the mandible without touching bone (Figure16.9).
● Needle insertion. The following is recommended to min-
imize discomfort associated with injection:
○ The intraoral finger should stretch and tighten the
mucosa overlying the pterygotemporal depression.
○ A light but firm tap followed by quick insertion is
regarded as the optimal technique. The site is lightly
but firmly tapped with the non- dominant hand while
at the same time quickly inserting the needle to hit
Figure16.9 Syringe positioned at contralateral mandibular
molars (rather than premolars) when the divergent angle of the
ramus of the mandible is >18° (conventional approach). Source:
Redrawn from Roberts and Sowray (1987).
bone. This maneuver is crucial because if the pain
threshold’s peak traumatic stimulus (the needle
advancing through the soft tissues) lasts too long it
will exceed the initial threshold, giving rise to pain
(Fuller etal.1979). Slower insertion triggers the initial threshold and if a few drops of anesthetic are
injected as the needle advances the pain rises
(Nusstein et al. 2006; McCartney et al. 2007;
Chapter13 Appendix); moreover, the anesthetic does
not take immediate effect. The factor that causes
most pain in truncal blocks is needle movement
(Annex 23).
● Insertion depth.
○ The insertion depth is the distance between the ante-
rior edge (pterygotemporal depression) and the sulcus
colli, where the inferior alveolar nerve lies in a wide-
open mouth. That distance is around 20–25 mm, rang-
ing from 15 to 30 mm (Table 16.4), and in children
under 6–8 years old it is 15–20 mm.
○ Inserting the needle into the hub is a technical error
for two reasons: this is the weakest area and may result
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Mandibular Anesthesia I: Pulpal Anesthesia
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Table16.4 Needle insertion depth insoft tissue inconventional mandibular block.
Reference Sample size Factor assessed Mean (mm) Range (mm)
Angelman (1945) 300 Patient — 18–33
Bremer (1952) 100 Dry mandible 24
± 3.1 16–32
Waikakul and Punwutikorn (1991) 68 Patient 20–25 —
Kronman etal. (1994) 39 Corpse 22 ± 1.8 15–28
Delgado-
Molina etal. (1999) 246 Patient 21 10–34
Hannan etal. (1999) 40 Patient 19 18–20
Tofoli etal. (2003) 20 Patient 20–25 —
Simon etal. (2010) 38 Patient 19 ± 3.2 —
Mean 21.7 15.4–29.4
Rounded mean 20–25 15–30
in needle breakage as well as the fact that the depth is
excessive to hit the landmarks for anesthesia of the
inferior alveolar nerve.
○ The insertion depth may vary (Angelman 1945)
depending on:
■ The divergent angle between the ramus of the man-
dible and the sagittal or medial plane; the greater
the divergent angle, the deeper the insertion.
■ The width of the ramus of the mandible; the wider,
the deeper.
■ The thickness of the mucosa and adipose tissue that
comprise the wall of the pterygotemporal depression; the thicker, the deeper.
○ Interestingly, the dimensions in a given individual
may vary by 1–4
○ If the needle is not successfully inserted because it fails to
touch bone after 30
soon, in less than 15
mm between sides (Angelman1945).
mm or because it touches bone too
mm, the recommendation is to
aspirate and slowly remove the needle, injecting 0.25 to
0.5 of a cartridge (0.5–0.9 ml) to anesthetize the pterygomandibular space and facilitate a second, less painful
maneuver in a second attempt after a 1- minute wait.
● Pre- injection aspiration.
○ Once bone has been reached with the tip of the needle the
clinician should avoid exerting undue pressure to prevent
injury to the periosteum (causing post- injection pain)
and barb formation on the tip of the needle. If a barb
forms outwardly, when the needle is withdrawn from
the pterygomandibular space, the following structures
may become injured: nerves (leaving persistent paresthesia in the lingual or inferior alveolar nerves), muscles (trismus due to injury to the medial pterygoid or
temporal muscles), and the inferior alveolar artery and
vein (hematoma) (Stacy and Hajjar1994).
○ After touching bone the needle is drawn back 1–2 mm
to aspirate. Aspiration is positive in 10% of cases
(Annex 22), one of the highest rates in dental local
anesthesia.
● Injection of the anesthetic solution and lingual nerve
anesthesia.
○ A 1.8- ml cartridge should be slowly injected, in 40–60
seconds. To anesthetize the lingual nerve the needle is
slowly withdrawn along the same path as it was
inserted through; at mid-
distance and prior to remov-
ing the needle, a second aspiration is performed and
the last ±0.3
ml in the cartridge is injected to anesthe-
tize the lingual nerve.
○ In the absence of this maneuver, the lingual nerve is
often anesthetized by diffusion across the pterygomandibular space. However, this maneuver ensures anesthesia of the lingual nerve.
○ Many clinicians aspirate every 0.25–0.50 ml, seeking to
further guarantee the safety of the injection with a
series of negative aspirations (McClure 1968;
Lloyd 1992); this also helps retard the injection by
curbing the natural tendency to move faster.
● Amount to be injected
○ In adults, teenagers, and older children, a 1.8- ml car-
tridge is used (1.5 ml during deposition and ±0.3 ml
while removing the needle to anesthetize the lingual nerve).
○ In children <6–8 years old, only ½ of a cartridge is needed.
● Subjective symptoms of anesthesia.
○ Soft tissue anesthesia appears in the lower lip on the
anesthetized side. Soft tissue anesthesia may be
described as tingling, numbing, itching, dullness, feeling “pins and needles,” and feeling a “fat lip” sensation (Table13.1, Chapter13). The onset of soft tissue
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