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Basic Injection Technique
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232
subconscious use of both sides during chewing. It is also
important to be careful with very hot drinks and
cigarettes (risk of burn).
3) Children. Stress both to them and their parents or
guardians that they must not bite their tongue, lips, or
buccal mucosa while they are anesthetized, since it will
hurt and they could injure themselves. Little children
tend to bite themselves repeatedly when they see that it
does not hurt. A trick used by many pediatric dentists is
to place a cotton roll between the lips or between the
cheek and the gum for as long as the anesthetic lasts to
remind children not to bite themselves (Mink and
Spedding1966).
4) With respect to the dose of anesthetic, it is important to
remember the following:
● Topical anesthesia also contributes to the total dose
administered (Cannell1996; Meechan1998).
● When it is necessary to inject a large quantity of anes‑
thetic solution, try to reserve 20–25% of the absolute
maximum dose to address unexpected events
(Meechan1998).
● Do not dispose of the empty cartridges after adminis-
tration. Keep them until the procedure is complete in
order to know exactly how much anesthetic has been
administered, especially in cases where it is necessary
to administer new injections halfway through treat‑
ment (Meechan1998).
● Remember the patient’s height and weight, especially
in the case of children and small adults (often elderly
persons) to minimize the risk of overdose (Goodson
and Moore1983; Hersh et al.1991; Virts 1999). See
Annex 10 on maximum doses.
5) Used needles should be disposed of in a safe container
for sharps and contaminated instruments (Dentists’
Desk1983).
2) The advance of the needle across the soft tissue until it
reaches its target in truncal block (Annex 23 and
Appendix). The pain can be relieved with a continuous
monolog and the rapid advance of the needle toward its
objective with counter‑ stimulus maneuvers.
3) Injection of acidic solutions (low pH). Solutions
containing sympathomimetic vasoconstrictors, such as
epinephrine also contain antioxidants (sulfites), which
reduce the pH (Annex 14). This leads to an initial sensa‑
tion of stinging and burning, as shown in clinical trials
(Oikarinen et al. 1975; Moorthy et al. 1984; Kramp
etal.1999; Wahl etal.2001). Fortunately, this effect dis‑
appears quickly, since tissue fluids contain buffers
which neutralize the pH. A smooth and short massage
can help to relieve this sensation.
4) The speed of the injection. This factor has been consid‑
ered important since the early years of dental local
anesthesia (Lewis 1919), and this remains the case
today (Malamed 1986; Roberts and Sowray 1987;
Linscott et al. 1978). Clinical trials have clearly proven
this impression (Mamiya et al. 2001; Primosch and
Brooks2002; Kudo2005; Kanaa etal.2006; Whitworth
etal.2007), especially in buccal infiltrations (Annex 23).
The explanation is that a rapid injection leads to a sud‑
den distension of the tissues, which increases pressure
and is painful. This specific factor is more painful than
the needle insertion (Nist etal.1992; Quarnstrom and
Libed1994; Carr and Horton2001a; Kennedy etal.2001;
Wiswall etal.2014). It can be mitigated by slow injec‑
tion and a continuous monolog.
FactorsThatPlayaRoleinPain
Regardless of the objective causes of pain, a series of factors
contribute to the perception that pain is more intense.
CausesofPainDuringtheInjection
Below, we analyze the real causes of pain, factors that play
a role in pain, and factors that are of almost no importance
but that many dentists still believe to be relevant.
FactorsThatCausePain
1) The injection. Insertion/penetration of the needle into
the mucosa is the main cause of pain during the
injection (Annex 19). It can be mitigated by the follow‑
ing: (i) using topical anesthetic before the injection and
(ii) distracting the patient with counter‑ stimulus
maneuvers (traction, stretching, pressure) and a
continuous monolog.
1) The part of the mouth where the injection is performed.
The clinical impression is that the palate is the part
where most pain is felt (Kramp et al. 1999; Wahl
etal.2001; Primosch and Brooks2002); this impression
is confirmed in the literature (Annexes 19 and 23).
Furthermore, it is known that pain is most intense in
the anterior part of the hard palate than in the posterior
part (Meechan etal.2005; Ozec etal.2010). Other sites
where pain is more intense include buccal periapical
infiltrations in the anterior teeth of the maxilla; in con‑
trast, buccal periapical infiltrations in the posterior
teeth of the maxilla are the least painful (Annex 23).
2) The patient’s age and sex. Most anxiety and sensitivity
to pain during injection of local anesthetic and dental
treatment in general is observed with women (LeClaire
etal.1988; Liddell and Locker1997; Baht etal. 2000;
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Van Wijk and Hoogstraten2006; Meechan etal.2005),
and adolescents and young adults (Kleinknecht and
Berstein 1978; LeClaire et al. 1988; Liddell and
Locker 1997; Wahl et al. 2001; Maggirias and
Locker2002; Gazal2015).
3) Intense anxiety reduces the pain tolerance threshold
and makes it more likely that nonpainful stimuli (e.g.
pressure) are interpreted as painful, therefore anxious
patients overestimate the degree of pain that dental
treatment causes (Wepman 1978; Corah et al. 1979;
Woolgrove1983; Sokol etal.1985; LeClaire etal.1988;
Maggirias and Locker2002; Van Wijk and Makkes2008)
and can enter a vicious cycle of overestimating pain and
increasing anxiety.
4) The dentist. Many physicians agree that the main factor
in reducing pain during the administration of anesthe‑
sia is the dentist him/herself (Mollen etal.1981; Goodell
etal.2000; Saloum etal.2000; Nusstein and Beck2003;
Ram and Peretz2003), for two key reasons:
● The dentist’s touch, skill, and ability when adminis‑
tering local anesthetic. Many of these small details
have been addressed in this chapter during the 10
phases of injection, where emphasis was placed on
safety, psychology, careful management of oral tis‑
sues, and the ways pain can be reduced during the
injection. It is of critical importance that the that cli‑
nician maintains an optimistic demeanor before, dur‑
ing, and after the injection process (Kravitz2006).
● The dentist’s management of the interpersonal rela‑
tionship, improved communication, and use of psy‑
chological strategies that increase patient satisfaction
(Gale etal.1984; Maggirias and Locker2002). Patient
satisfaction may even be high in treatments that are
painful (Lindemann etal.2008) owing to the dentist’s
positive and professional approach (i.e. not appearing
indifferent or being on the defensive) and the fact that
he/she gives the patient encouragement, especially at
difficult points during the procedure. While not
within the scope of this book, some aspects are wor‑
thy of mention (Gale etal.1984):
– Welcome the patient and ask him/her to sit in the
dental chair.
– Explain what is going to be done.
– Approach the patient carefully.
– Talk about things in general when administering
the anesthetic.
– Explain to the patient during the treatment that
everything is going well. Even if a problem arises,
we can say something like “This is interesting, but
we’ll have it fixed in second.” Note the use of the
euphemism “interesting” and not words such as
“problem” and “difficulty.”
– Converse with the patient on completion of treat‑
ment and say goodbye.
Patient expectations of pain and anxiety are not mod‑
ified by a simple pain
exposures to pain
‑ free procedure; however, repeated
‑ free treatment attenuate expectations
of anxiety and pain (Maggirias and Locker2002).
Finally, it is important to remember that the two princi‑
pal factors by which patients judge dentists are whether
they administer the injection without pain and whether
there is pain during the procedure (St Georges2004).
UnimportantCauses(Myths)
There are two myths that, unfortunately, are widespread
among dentists with respect to the cause of pain during
injection. They are of little relevance.
1) The needle caliber myth. Most dentists think that
smaller calibers (30G and 27G) cause less pain during
the insertion and the injection (Smith1968; Cooley and
Robinson1979; Mollen et al. 1981; Van der Bijl1995).
However, clinical studies seem to indicate that there is
little difference with respect to perception of pain (see
Chapter11). Six clinical trials found no statistically sig‑
nificant differences in pain with the different calibers of
needle (30G, 27G, and 25G), and a further two trials
showed that the finest
‑ gauge needle (30G) caused less
pain than the 27G needle. The clinical differences were
very small but statistically significant (Table 11.3,
Chapter11).
To verify differences between the calibers, we must
use thicker needles (20G or 22G), such as those used in
intramuscular injections or those that were once used
in dental injections (Smith1920).
2) The cartridge temperature myth. Even in the earliest
texts on dental local anesthesia, authors insisted that
solutions be at body temperature (around 36 °C) to
prevent pain during the injection (Fischer 1912;
Lewis1919).
Clinical trials have shown that patients cannot distin‑
guish between ambient temperature (20–21 °C) and
injections at body temperature (35–37 °C) (Oikarinen
etal.1975; Rood1977; Ram etal.2002).
Furthermore, heating the cartridges for a short time
is harmless, although storing them at body temperature
for long periods deteriorates sympathomimetic vaso‑
constrictors such as epinephrine (Gerke etal.1977; Fry
and Ciarlone1980; Thoma and Struve1986; Hondrum
etal.1993).
If the cartridge is cold (less than 20 °C=68 °F), it can
be heated up before placing it in the syringe by holding
it in the hand for 30 seconds (Malamed2004).
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234
Terminology
Below, we classify dental anesthesia and comment on the
terms used to define the different anesthetic techniques
(Jorgensen and Hayden 1970; Allen 1979; Jastak
etal.1995).
● Classification of anesthesia with respect to the
periosteum:
– Infraperiosteal or subperiosteal. When the needle goes
below the periosteum to deliver the anesthetic solu‑
tion at this level. The technique was used many years
ago, when anesthetic solutions were weak, so that they
could cross a barrier (the periosteum), penetrate more
deeply, and thus cross the cortical bone to reach the
cancellous bone. The approach is complicated by pain
during penetration of the periosteum and post
operative pain.
– Supraperiosteal or paraperiosteal. When the needle
remains above the periosteum and does not cross it.
Today, all techniques are supraperiosteal because mod‑
ern anesthetic solutions cross the periosteum well.
● Classification of anesthesia according to basic techniques
(Figure13.11):
– Topical or surface anesthesia, which results from
application of the anesthetic on the oral mucosa with‑
out administering an injection.
– Infiltrative anesthesia, which involves injection of
anesthetic solution into the tissues to be treated.
Several nerve endings (many of which are micro‑
scopic) are anesthetized. Anesthesia is limited to the
area reached by the solution.
– Nerve or truncal block, which involves anesthesia of a
whole nerve or nerve trunk (macroscopic), such as the
inferior alveolar nerve (mandibular block). The advan‑
tage of this approach is that it anesthetizes at some
distance and thus covers a large anatomical area.
Note: Nerve blocks can be of smaller secondary trunks;
some authors call these blocks “field blocks” or “regional
blocks.” We refer to them all as nerve blocks, for example
maxillary nerve block (V
) via the high tuberosity (main
2
nerve trunk) and anterior superior alveolar nerve block
via the infraorbital nerve (secondary trunk) (see
Chapter14).
● Variants of infiltrative techniques:
– Periapical or para‑ apical anesthesia. The filtration
placed at the apex of the teeth (buccal infiltration).
– Intrapapillary anesthesia. Infiltration in the interden‑
‑
tal papilla (Figure13.12).
– Plexus anesthesia. Anesthetic administered by infiltra‑
tion of the superior dental plexus or superior alveolar
nervous plexus in the maxilla at the level of or above
the apexes of the teeth at the junction of the posterior,
medial, and anterior alveolar nerves, and even the
nasopalatine nerve in the anterior part (see Chapter2).
– Transpapillary technique. Infiltration of the interden‑
tal papilla to anesthetize the palate through the buc‑
cal part.
– Intrapulpal anesthesia. Injection directly into the open
dental pulp.
– Intraosseous anesthesia. Penetration of the needle
into the cancellous bone after crossing the periosteum
and cortical bone to inject directly into the trabecular
or cancellous bone.
Figure13.11 Basic techniques in dental local anesthesia: (1)
topical anesthesia; (2) infiltrative anesthesia; (3) nerve trunk
block; and (3b) smaller, secondary nerve trunk block (field or
regional anesthesia or field block). Source: Redrawn from Allen
(1979) and Jastak etal. (1995).
3 Block
3 b Block
2 Inf
1 Topical
Figure13.12 Intrapapillary infiltrative anesthesia.
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– Intraligamentous anesthesia or anesthesia of the peri‑
odontal ligament. A pressure injection across the peri‑
odontal ligament.
– Intraseptal anesthesia. Penetration of the needle into
the interdental papilla to perforate the interdental
bone crest and inject the anesthetic solution into the
cancellous bone. This is a variant of the intraosseous
and intraligamentous techniques.
Appendix
Data from McCarney etal. (2007).
Mandibular block. Pain in scale of none, mild, moderate,
and severe. Pain during advance of the needle (needle
placement) in a group with deposition of anesthetic
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Maxillary Anesthesia I: Pulpal Anesthesia
241
Introduction
This chapter on pulpal anesthetic methods for the upper
arch (maxillary) teeth addresses the following procedures.
● Buccal infiltration anesthesia and the variation known
as the modified cotton roll approach.
● Intra- and extraoral infraorbital nerve block as an
approach to block the anterior superior alveolar nerve.
● Posterior superior alveolar nerve block (PSA) and the
variation known as the modified Adatia technique.
● High tuberosity approach to block the maxillary nerve
) through the mucobuccal fold.
(V
2
● Transpalatal approach (also known as the greater palatine
canal technique) to block the maxillary nerve (V
The chapter also reviews certain aspects affecting the
anesthesia of maxillary teeth to provide a fuller understanding of the anesthetics used.
Maxilla
The thin layer of porous cortical bone in the maxilla is
perforated by many small foramina through which the
anesthetic solution can diffuse (DuBrul1988). As the tooth
apices are very close to the cortical surface (Table 2.7,
Chapter2), the technique of choice in most cases is buccal
infiltration, in light of its efficacy, simplicity, and safety.
Another advantage to the technique is that more than one
tooth can be anesthetized with more infiltration.
Maxillary Nerve (V2)
The second division of the trigeminal (cranial nerve V), the
maxillary nerve, distributes to three superior alveolar nerves
(anterior, middle, and posterior) that innervate the dental
pulp. In over 80% of individuals these branches intermingle
).
2
in a superior dental plexus at the dental apices (Table2.3,
Chapter2), although the middle superior alveolar nerve is
missing in just under 50% (Table2.2, Chapter2). As those
circumstances render independent block of each branch
very difficult, the procedure actually used is buccal infiltration near the apex of the teeth, which affects all three.
Buccal Anesthesia ofthe Upper Molars
Inserting the needle in the buccal cavity around the upper
molars may involve three types of anesthetic techniques,
depending on needle depth and angle (Figure 14.1): the
deeper the penetration and the wider the angle, the greater
the number of teeth affected, although the risk of causing
hematomas by penetrating pterygoid plexus vessels is also
greater.
● Buccal infiltration of the molars is the simplest and most
effective technique for anesthetizing molar pulp. As the
needle need not be inserted very deeply, the risk of
hematoma is minimal.
● PSA (Posterior superior alveolar nerve block) or the
tuberosity approach is a more complex technique because
the needle is inserted higher and at a wider angle to skirt
around the posterior wall of the maxilla (tuberosity) and
reach the foramina through which the one to four
branches forming this nerve trunk transmit. This technique anesthetizes molars as well as premolars, albeit
less effectively. The likelihood of causing hematoma is
logically greater with this method and part of its clinical
efficacy is due to the buccal infiltrative effect, for the
solution diffuses across the molars.
● The high tuberosity approach is designed to block the
maxillary nerve (V
) in the pterygopalatine fossa. This
2
technique is even more difficult and arbitrary than the
tuberosity approach due to the lack of osseous references
to guide the needle during injection. The needle is
Local Anesthesia in Dentistry: A Locoregional Approach, First Edition. Jesús Calatayud and Mana Saraghi.
© 2024 John Wiley & Sons Ltd. Published 2024 by John Wiley & Sons Ltd.
Companion website: www.wiley.com/go/Calatayud/local
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