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thefundoplication.
UNDOPREVIOUSFUNDOPLICATION
■
Findingtheinferioredgesofthefundoplicationwhereitdrapesoverthe
proximalstomach,especiallyontheleftsideofthegastriccardia,allowsthe
edgetobetracedtowardtheanteriorfusionofa360-degreefundoplication.A
similarexposureontheleftcanalsobeaccomplished,buttheleftloweredge
ofthefundoplicationtendstobemorefusedalongtheneurovascularbundles
ofthelessercurve.
■
Oncetheanteriorfusionofthefundoplicationisfound,itcanbeisolatedand
eitherreleasedwiththeaidofelectrocauteryorseparatedbyfiringalinear
cuttingstaplerbetweenthetwolimbs(FIG14).
■
Withtheanteriorportionofthefundoplicationreleased,therightlimbis
dissectedawayfromthelessercurveofthestomachandrightsideofthe
esophagusandreturnedtoitsnormallocationintheleftupperquadrant(FIG
15).Asthefundoplicationisdissectedawayposteriorly,theposteriorvagus
nerveshouldbesoughtandprotected.

■
Withthefundoplicationcompletelyundone,anEGDisagainperformedto
assurethatthewrapiscompletelymobilizedandassessforanyperforation.
Thisisdonebysubmergingtheareaofthegastroesophagealjunction(GEJ)
undersalinewhileinflatingthelumenoftheesophagusandstomachwithair
andlookingforanairleakexternally.
RECONSTRUCTESOPHAGEALHIATUS
■
Theesophagealhiatusisreconstructedusingpermanentsuturestoapproximate
thecruraposteriorly.Pledgetscanbeusedtolimitthesawingeffectofthe
sutureovertime(FIG16).

■
Ifthehiataldefectislarge,theintraabdominalpressureisdecreasedto10to12
mmHg,therebyunloadingthepressureonthediaphragmandcruralrepair.
■
Severalanteriorcruralsuturesmaybeneededifthedefectislargeandthe
posterior-onlyclosureiscreatinganangleattheGEJ.
■
Thecruralreconstructionshouldresultinthecruraeffacingtheesophagus
circumferentiallywithoutimpinging.
REDOFUNDOPLICATION
■
Astandardtechniqueforfundoplicationcanbeused.
9,10
Thisentailsa360degreefundoplicationifthereisadequatefundusandthepreoperative
esophagealmotilityisadequate(peristalsisin70%ormoreofswallowsor
esophagealbodypressureof30mmHgorgreater).A270-degree
fundoplicationshouldbeusedifthesecriteriaarenotmet(Table6).

■
Fundoplicationshouldbecalibratedbycompletingthewraparounda56-to60-
FrdilatorplacedacrosstheGEJ(FIG17).Itisbestifthefundusispositioned
forthefundoplicationbeforethisdilatorisplaced;otherwise,thewrapcanbe
verydifficulttobringaroundtheesophagusposteriorlywiththedilatorin
place.
■
Twotothreepermanentsuturesthatincludetheanterioresophagusareplacedto
producea2-cmlongfundoplication.
ASSESSFORPOTENTIALCOMPLICATIONS
■

OnefinalEGDisrecommendedtoassessthelocationofthewrapandlookfor
anypotentialcomplications.Aretroflexviewisveryhelpfultoassurethatthe
wrapisonthedistalesophagusandnottheproximalstomach(theappearance
ofgastricfoldsextendingupandintothewrapsuggestsawrapthatistoo
low).
CONSIDERADJUNCTS
■
Ifthehiataldissectionorundoingthewrapwasparticularlydifficult,a
gastrostomytubecanbeusedtoallowgastricdecompressionandpossible
gastricfeedswhilewaitingforproximalgastrointestinal(GI)functionto
returnandnormalize.
PEARLSANDPITFALLS
Indicationsforsurgery
anddiagnosisof
failure
■Functionalreasonsforsymptomsafter
fundoplication(e.g.,misdiagnosedGERD,otherGI
problems,vagalnerveinjury)cannotbecorrected
withsurgery.
■Withoutevidenceofanobviousanatomicfailureor
confirmationofrecurrentGERDbypHtesting,
surgeryshouldbeavoided.
Preoperativetesting ■Preoperativetestsareintendedtoassurethatcorrect
redotechniqueisperformed(e.g.,totalvs.partial
fundoplication).
■Skippingtestingmaycompromiseredosuccess.
Identifyandexpose
hiatalanatomy
■Injurytotheliver,lessercurveofthestomach,the
wrap,andtheesophagusismorelikelyifdissection
isstartedontheright.
■Startingontheleftallowsexposureofthehiatus
beforeworkinginthemoreanatomicallycongested
rightside.

Intraoperativetesting ■Liberaluseofintraoperativeendoscopytoguide
dissectionbyfrequentlyassessinganatomy
■Assessforpotentialluminalinjurypenetration.
Surgicaltechnique ■Astandardizedtechniqueadheringtokeytechnical
principleswillhelpassuresuccessfuloutcomes
(Table7).
Postoperativecare ■Managingnauseatopreventretchingstartsinthe
operatingandrecoveryroomandiscriticalto
minimizingtraumaearlypostoperativethatcould
disrupttheredo.
■Gastricdecompressionavoidsgastricdistensionthat
coulddisruptawraporcruroplasty.
■Tubeaccesstothestomachmayallownonoperative
managementofasmallleakfoundpostoperatively.
POSTOPERATIVECARE
■
Postoperativemanagementafterreoperativeantirefluxsurgerymirrorsthecare
ofanyforegutsurgerypatient.Aone-totwo-nightstayisprettytypicalifthe
redoislaparoscopic,extradaysifopen.Keyaspectsofpostoperativecareare
oralintakeandreturntoactivity.
■

Apreventablecauseofantirefluxsurgeryfailureisearlypostoperativeretching.
Thetwomostcommonreasonsforearlypostoperativeretchingarenausea
anddietaryindiscretion.
■
Patientsshouldreceivepreemptivenauseacontrolandantiemeticsandbe
counseledcarefullyaboutmaintainingaliquidandsoftfooddietforatleast1
monthaftersurgery.
■
Instructingpatientstoingestonlypourableliquidsforthefirstweekafter
surgeryprovidesasimpleruletofollow,andthenprovidingadetailedmenu
ofacceptablesoftfoodsforanother3weekswillhelpeffectcompliancewith
thepostoperativediet.
■
Toorapidadvancementtoactivitythatwillresultinincreasedintraabdominal
pressurecanputsuturesandthereconstructedanatomyatrisk.Afull30days
oflimitingliftingtonomorethan30lbandnovigorousexerciseduringthis
timeprovidessimpleguidelinesforpatientstofollow.
■
Settingappropriateexpectationsforpatientswithregardtotheiroverall
recovery,dietprogression,andresolutionofpreoperativesymptomsis
important.Dysphagiamaylingerformorethan4weeksafteraredoand
preparingpatientsforthislikelihoodwillallowthemtoacceptthismore
readily.
■
Earlydilationmayimprovethedysphagia,butitalsoincreasestheriskof
recurrentGERDandthereforeshouldbeavoidedifpossible.Wereserve
dilationwithinthefirst3monthsafteranyantirefluxoperationforonlythose
patientswhosedifficultyswallowingmakesithardtohandletheirownsaliva
ormaintainhydration.
OUTCOMES
■
Theoutcomesofredofundoplicationcanbecomparabletoprimaryantireflux

surgery,andinpatientssufferingwithsignificantanddebilitatingsymptoms,
theoperationscanreturnpatientstoanearlynormalqualityoflifewithlow
morbidityandvirtuallynomortality11(Table8).
■
Thepatientrequiringmultiplereoperationsforfailedfundoplicationisaspecial
situationthatdeservesspecialmention.Whenundertakingafourthredo,the
failureratejumpsfromaround7%toover17%.7Wewillrarelysimply
undertakearedoafterthreepriorattempts.AdividedgastroplastyandRouxen-YreconstructionforrecurrentsevereGERD,anesophagogastricmyotomy
forpseudoachalasiaoresophagectomyforseverepseudoachalasiawith
massivelydilatedesophagus,oranesophagojejunostomyforpooresophageal
emptyingwithsevereGEJdistortionisinsteadadvised.
COMPLICATIONS
■
Complicationscanbestbeunderstood,identified,andmanagedconsideringtheir
occurrence.
Intraoperative
■
Bleeding
■
Liverinjury
■
Esophagogastricperforation
■

Pneumothorax
■
Vagalnerveinjury
Postoperative
■
Pneumonia
■
Esophagealobstruction(edema)withinabilitytoswallow
■
Delayedgastricemptying
■
Atelectasisandhypoxemia
REFERENCES
1.DallemagneB,PerrettaS.TwentyyearsoflaparoscopicfundoplicationforGERD.WorldJSurg.
2011;35:1428–1435.
2.MorgenthalCB,LinE,ShaneMD,etal.WhowillfaillaparoscopicNissenfundoplication?
Preoperativepredictionoflong-termoutcomes.SurgEndosc.2007;21:1978–1984.
3.OelschlagerBK,MaKC,SoaresRV,etal.Abroadassessmentofclinicaloutcomesafter
laparoscopicantirefluxsurgery.AnnSurg.2012;256:87–94.
4.BroedersJA,RoksDJ,DraaismaWA,etal.Predictorsofobjectivelyidentifiedrecurrentreflux
afterprimaryNissenfundoplication.BrJSurg.2011;98:673–679.
5.EngströmC,CaiW,IrvineT,etal.Twentyyearsofexperiencewithlaparoscopicantireflux
surgery.BrJSurg.2012;99:1415–1421.
6.SalminenP,HurmeS,OvaskaJ.Fifteen-yearoutcomeoflaparoscopicandopenNissen
fundoplication:arandomizedclinicaltrial.AnnThoracSurg.2012;93:228–233.
7.SmithCD,McCluskyDA,RajadMA,etal.Whenfundoplicationfails:redo?AnnSurg.
2005;241:861–869;discussion869–871.
8.ParkerM,BowersSP,BrayJM,etal.Hiatalmeshisassociatedwithmajorresectionatrevisional
operation.SurgEndosc.2010;24:3095–3101.
9.DallemagneB,ArenasSanchezM,FrancartD,etal.Long-termresultsafterlaparoscopic
reoperationforfailedantirefluxprocedures.BrJSurg.2011;98:1581–1587.
10.LégnerA,TsuboiK,BathlaL,etal.Reoperativeantirefluxsurgeryfordysphagia.SurgEndosc.
2011;25:1160–1167.
11.vanBeekDB,AuyangED,SoperNJ.Acomprehensivereviewoflaparoscopicredo
fundoplication.SurgEndosc.2011;25:706–712.

Chapter7
LaparoscopicPartial
Fundoplicationfor
GastroesophagealReflux
Disease
MarcoE.AllaixMarcoG.Patti
DEFINITION
■
Gastroesophagealrefluxdisease(GERD)isachronicconditionresultingfrom
therefluxofgastriccontentsintotheesophagusandisassociatedwitha
spectrumofsymptoms,withorwithouttissueinjury.
1,2
DIFFERENTIALDIAGNOSIS
■
Severalconditions,includingirritablebowelsyndrome,achalasia,gallbladder
disease,coronaryarterydisease,orpsychiatricdisorderscanpresentwith
heartburnasthemainsymptom.
PATIENTHISTORYANDPHYSICALFINDINGS
■
Heartburn,regurgitation,anddysphagiaareconsideredtypicalsymptomsof
GERD.
■
GERDcanalsocauseatypicalsymptomssuchascough,wheezing,chestpain,
hoarseness,anddentalerosions.
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