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Aftertyingthesefundoplicationsutures,thesilksuturelineisoversewnwitha
4-0PDSrunningLembertsuturetominimizetheriskofaleakfromthe
fundoplicationsutures(FIG13C).
CompletionoftheHiatalHerniaRepair
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Theesophagealdilatorisremovedanda16-Frnasogastrictubeisplaced.
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Thefundoplicationisreducedthroughthehiatusandissecuredtothe
undersurfaceofthediaphragmwiththreeinterrupted2-0Prolenehorizontal
seromuscularmattress“Belsey”sutures,whicharepassedthroughthe
diaphragmaroundthecircumferenceofthehiatus(FIG14B,C).Caremustbe
takenduringpassageofthemostanteromedialsuturetopreventinadvertent
injurytotheheartandpericardialtamponade.

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Theposteriorcruralsuturesaretieduntilthediaphragmatichiatuspermitsthe
passageofanindexfingeralongsidethedistalesophagus(FIG15A,B).The
Belseysuturesarethentied,andthecompletedfundoplicationshouldrest
belowthediaphragmwithouttension(FIG15C).

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Hemoclipsareusedtomarkthehiatusforlocalizationonimaging.
ThoracotomyClosure
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Ifaparaspinouscatheterwillbeusedforpaincontrol,apleuralflapisraised
posteriorly.Aparaspinouscatheterisplacedpercutaneouslyundertheflap
andsecuredtotheskinwith2-0nylonsuture.Thepleuralflapis
reapproximatedtothechestwallwith4-0Vicryl,allowinglocalanestheticto
beinfuseddirectlytotheaffectedintercostalnerves.
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A28-Frchesttubeisinsertedthroughalowintercostalincision,advancedtothe
apex,securedtotheskin,andconnectedtounderwatersealdrainage.Theribs
arereapproximatedwithinterruptedno.2Vicrylsuturesplacedaroundthe

6thribandthroughholesdrilledinthe7thribusingamicrodrilltoavoid
nerveentrapmentagainstthelowerrib.
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Thewoundisthenclosedinlayersreapproximatingtheserratusandlatissimus
muscleswithrunning2-0Vicryl,thesubcutaneoustissueswith2-0Vicryl,
andtheskinwitharunning4-0Monocrylsubcuticularsuture.
PEARLSANDPITFALLS
Preoperative
evaluation
■Discussandmodifyriskfactorsforrecurrenthernia
preoperatively,especiallyweightlosswithagoal
bodymassindex(BMI)<32.
■Atransthoracicapproachwithanesophageal
lengtheningprocedure,similartoarelaxingincision
foraninguinalherniarepair,maybeoptimaleven
forsmallslidinghiatalherniasinmorbidlyobese
patientsduetotheincreasedriskofrecurrence.
Positioning ■Duetothepositionoftheliver,thehiatuscannotbe
adequatelyapproachedthroughtherightchest.All
transthoracichiatalherniarepairsshouldbe
approachedthroughaleftthoracotomyevenwhen
theherniaisintherightchest.
Incisions ■Forsmallerhernias,thehiatalherniarepairmaybe
easiertoperformthroughthe7thintercostalspace,
butthelowertheinterspaceincision,thegreaterthe
degreeofpostthoracotomypainbecausemorechest
wallsensorynervesaredivided.
Intraoperative ■Usingastockinette,acloth-coveredHarrington
retractorisusedtoretractthediaphragmdownward
toimproveexposureofthehiatus,andaspoon
retractorisusefultoprotecttheintraabdominal
contentswhenplacingthecruralsutures.
■Theanteriorattachmentsofthehighlessercurvature

maycontaintheascendingbranchoftheleftgastric
arteryandshouldbeligatedanddivided.
■Acounterincisionparalleltoand1to2cmfromthe
hiatuscanbemadeinthediaphragmifadditional
exposureisneededduringaredohiatalhernia
repair.
■Itisessentialtocommunicatewiththeperson
passingthebougietoensurethatthesurgeon’shand
ispalpatingandguidingthebougieasitisbeing
passedtopreventperforation.
■CareshouldbetakenduringformationoftheCollis
gastroplastynottoapplythestaplereithertoo
tightlyagainstthebougie,narrowingthe
gastroplastytubeor,soloosely,creatingapouch
thatemptiespoorly.
■Wedonotrecommendtheroutineuseofmeshdue
totheriskofesophagealerosion.Atransthoracic
approachallowsadequatebitestobetakenofthe
crura,whicharethentiedwithoutunduetension.
■Hemoclipmarkersareplacedatthenew
gastroesophagealjunctionandthediaphragmatic
hiatusforlocalizationonimaging.Thedistance
betweenthetwolevelsofclipsrepresentsthe
intraabdominallengthofthedistal“neoesophagus.”
Closure ■Theribsarereapproximatedwithinterruptedno.2
Vicrylsuturesplacedaroundthe6thribandthrough
holesdrilledinthe7thribusingamicrodrillto
avoidnerveentrapmentagainstthelowerrib.
■Achestx-rayisobtainedintheORattheendofthe
casetoconfirmreexpansionofthelungsandto
evaluateforarightpneumothoraxoreffusion,
whichmayrequirechesttubeplacementiftheright
pleurawasentered.

POSTOPERATIVECARE
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Thenasogastrictubeisplacedtolowcontinuoussuction.Onpostoperativeday
2,thenasogastrictubeisplacedtogravityandremovedonpostoperativeday
3iftoleratedandtheoutputremainslessthan200mLpershift.Thepatientis
thenstartedonclearliquidswithnopills.Onpostoperativeday4,thedietis
advancedtofullliquidsandthenasoftdiet.
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Thechesttubeisplacedto20cmofwatersuction.Chesttubesmayberemoved
onpostoperativeday2oncethedrainagehasdecreasedtolessthan60mLper
shift.
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Patientsshouldbegivenanadequatepaincontrolregimenandencouragedto
ambulateandusetheincentivespirometer.
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Onpostoperativeday5,abariumswallowisobtainedtoassessthatcontrast
flowsfreelythroughtheesophagusandintothestomachandduodenumand
thatthefundoplicationisintactbelowthediaphragm.Patientsareseenbya
dieticianforeducationonapost–Nissenfundoplicationdiet.Theyare
dischargedonasoftdietfor2to3weeksandremindedtoavoidlargepills
andcarbonatedbeverages.
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Mostpatientsaredischargedhomebetweenpostoperativedays5and7.At
discharge,theimportanceofavoidingriskfactorsassociatedwithhernia
recurrence,includingheavylifting,constipation,orchroniccoughing,is
emphasized.
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Milddysphagiaoccursinlessthan10%ofpatientsandusuallyimprovesover4
to6weeksasthepostoperativeedemasubsides.
2
OUTCOMES
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Transthoracichiatalherniarepairremainsthestandardagainstwhichother
approachesarecompared.Pateletal.4described240patientsundergoing
repairofaparaesophagealhernia(92%typeIIIand8%typeIV)withan
antirefluxprocedureinallpatientsandaCollisgastroplastyin96%.Five
patients(2.1%)requiredanemergentrepair.Therewerethreeperioperative
deaths(1.7%),andthemedianlengthofstaywas7days.4Earlycomplications
includedrecurrenthernia(fourpatients),leak(threepatients),excessive
narrowingofthehiatus(threepatients),andbleeding(onepatient).Eighty-six
percentofpatientsweresatisfiedatlastfollow-up,withameanfollow-upof
42months.Ananatomicrecurrencewasfoundin23patients(10%),withfour
requiringearlyrepairandfourrequiringlatereoperation.
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Allenetal.9reportedtransthoracichiatalherniarepairsin147patientswith81
patients(68.1%)undergoingaCollis-Nissen,19(16.0%)aBelsey-MarkIV,
17aNissen(14.3%),and2aHarringtonrepair(1.7%).Therewereno
operativedeaths,andcomplicationsoccurredin32patients(26.9%).Witha
medianfollow-upof42months,resultswereexcellentin69patients(60%),
goodin38patients(33%),fairin6patients(5.2%),andpoorin2patients
(1.7%).Offivepatientswhounderwentemergentrepair,threehadgastric
necrosisandonedied.
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Maziaketal.5described94patientswithmassive,incarceratedparaesophageal
hernias.Organoaxialvolvuluswaspresentin50%ofpatients.Agastroplasty
wasperformedin75patients(80%)becauseofashortenedesophagus.There
weretwooperativedeaths.Themeanfollow-upwas94months,with72
patients(80%)freeofsymptomsand13patients(13%)having
inconsequentialsymptoms.Threepatients(4%)requiredmedicaltherapyor
esophagealdilationsandtwopatientshadrecurrentherniasorseverereflux
successfullytreatedwithareoperation.
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Rogersetal.20reportedaseriesof60patientswithaparaesophagealhernia.
Thirteenpatientsunderwentemergentrepair.Atransthoracichiatalhernia
repairwasperformedinallpatientswithanantirefluxprocedureadded
selectively.Therewasonedeathafteranemergentrepairandonerecurrence

(1.5%).Sevenpatients(12%)requiredasingleesophagealdilationandtwo
patients(3%)developedsymptomaticreflux.
COMPLICATIONS
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Bleeding
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Splenectomy
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Pericardialtamponade
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Rightpneumothoraxorpleuraleffusion
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Damagetothevagusnervesresultingingastricoutletobstructionordumping
syndrome
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Gastricleak
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Persistentdysphagiarequiringdilations
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Recurrenthernia
REFERENCES
1.StirlingMC,OrringerMB.Surgicaltreatmentafterthefailedantirefluxoperation.JThorac
CardiovascSurg.1986;92(4):667–672.
2.OrringerMB,SloanH.CombinedCollis-Nissenreconstructionoftheesophagogastricjunction.
AnnThoracSurg.1978;25(1):16–21.
3.SkinnerDB,BelseyRH.Surgicalmanagementofesophagealrefluxandhiatushernia.Long-term
resultswith1,030patients.JThoracCardiovascSurg.1967;53(1):33–54.
4.PatelHJ,TanBB,YeeJ,etal.A25-yearexperiencewithopenprimarytransthoracicrepairof
paraesophagealhiatalhernia.JThoracCardiovascSurg.2004;127(3):843–849.
5.MaziakDE,ToddTR,PearsonFG.Massivehiatushernia:evaluationandsurgicalmanagement.
JThoracCardiovascSurg.1998;115(1):53–60;discussion61–62.
6.WilliamsonWA,EllisFHJr,StreitzJMJr,etal.Paraesophagealhiatalhernia:isanantireflux
procedurenecessary?AnnThoracSurg.1993;53(3):447–451;discussion451–452.

7.GehaAS,MassadMG,SnowNJ,etal.A32-yearexperiencein100patientswithgiant
paraesophagealhernia:thecaseforabdominalapproachandselectiveantirefluxrepair.Surgery.
2000;128(4):623–630.
8.AltorkiNK,YankelevitzD,SkinnerDB.Massivehiatalhernias:theanatomicbasisofrepair.J
ThoracCardiovascSurg.1998;115(4):828–835.
9.AllenMS,TrastekVF,DeschampsC,etal.Intrathoracicstomach.Presentationandresultsof
operation.JThoracCardiovascSurg.1993;105(2):253–258;discussion258–259.
10.SchauerPR,IkramuddinS,McLaughlinRH,etal.Comparisonoflaparoscopicversusopen
repairofparaesophagealhernia.AmJSurg.1998;176(6):659–665.
11.HorganS,EubanksTR,JacobsenG,etal.Repairofparaesophagealhernias.AmJSurg.
1999;177(5):354–358.
12.DahlbergPS,DeschampsC,MillerDL,etal.Laparoscopicrepairoflargeparaesophagealhiatal
hernia.AnnThoracSurg.2001;72(4):1125–1129.
13.SwanstromLL,JobeBA,KinzieLR,etal.Esophagealmotilityandoutcomesfollowing
laparoscopicparaesophagealherniarepairandfundoplication.AmJSurg.1999;177(5):359–363.
14.HashemiM,PetersJH,DeMeesterTR,etal.LaparoscopicrepairoflargetypeIIIhiatalhernia:
objectivefollowuprevealshighrecurrencerate.JAmCollSurg.2000;190(5):553–560.
15.WiechmannRJ,FergusonMK,NaunheimKS,etal.Laparoscopicmanagementofgiant
paraesophagealherniation.AnnThoracSurg.2001;71(4):1080–1086.
16.HunterJG,SmithCD,BranumGD,etal.Laparoscopicfundoplicationfailures:patternsof
failureandresponsetofundoplicationrevision.AnnSurg.1999;230(4):595–604;discussion604–606.
17.YauP,WatsonDI,JamiesonGG,etal.Theinfluenceofesophageallengthonoutcomesafter
laparoscopicfundoplication.JAmCollSurg.2000;191(4):360–365.
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presentation,andtreatmentintheeraoflaparoscopicantirefluxsurgery.AnnSurg.2000;232(5):630–
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AnnRCollSurgEngl.2001;83(6):394–398.

Chapter5
LaparoscopicNissen
Fundoplication
ElizabethA.WarnerBrantK.Oelschlager
DEFINITION
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Gastroesophagealrefluxdisease(GERD),asdefinedbytheMontrealConsensus
Groupin2006,iscausedbygastricreflux,causingtroublesomesymptoms
and/orcomplicationstothepatientthatadverselyaffecttheirwell-being.
1
Symptomscanincludeheartburn,acidbrash,regurgitation,dysphagia,
noncardiacchestpain,andpulmonarysymptomssuchascoughand
hoarseness.Complicationsincludeesophagitis,Barrett’sesophagus,
esophagealstricture,andaspirationpneumonia.
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GERDresultsfromincompetencyordysfunctionoftheloweresophageal
sphincter(LES).ImportantfactorsforadequateLESfunctioninclude
esophagealcontraction,gastriccardiaslingfibers,diaphragmaticcrus,and
intraabdominalpositionoftheLEScomplex.Hiatalherniaseffacethenatural
valveanatomy,allowingtheGEjunctiontobedisplacedintothechest,
exposingtheLEStonegativeintrathoracicpressureandincreased
gastroesophagealreflux.Acertainamountofgastroesophagealrefluxis
physiologicandnotpathologic.However,oncesymptomsbecome
troublesometothepatient,adiagnosisofGERDcanbemade.
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GERDcanalsobeduetoinadequateesophagealmotilityresultinginpoor
clearanceofphysiologicreflux.Similarly,delayedgastricemptyingcanlead
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