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- •Contents
- •1.1.9 Laryngeal Atresia
- •1.1.10 Laryngeal Webs
- •1.1.11 Congenital Subglottic Stenosis
- •1.1.12 Laryngeal Cleft
- •1.1.13 Tracheoesophageal Fistula
- •1.1.14 Tracheal Bronchus
- •1.2.2 Mesenchyme Development
- •1.2.4 Lung Development
- •1.2.4.1 Embryonic Stage
- •1.2.4.2 Pseudoglandular Stage
- •1.1.1 Oral Cavity
- •1.1.2 Nasal Cavity
- •1.1.3 Palate
- •1.1.4 Primitive Pharynx
- •1.1.5 Upper Airway Anomalies
- •1.1.6 Cleft Lip/Palate
- •1.1.7 Choanal Atresia
- •1.1.8 Laryngomalacia
- •1.2.4.3 Canalicular Stage
- •1.2.4.4 Saccular Stage
- •1.2.4.5 Alveolar Stage
- •1.2.5 Congenital Respiratory System Defects
- •1.2.5.1 Tracheal Agenesis
- •1.2.5.2 Congenital Tracheal Stenosis
- •1.2.5.3 Lung Agenesis
- •1.2.5.4 Lung Hypoplasia
- •References
- •2.1 Introduction
- •2.2 Nasal Cavity
- •2.2.1 Vestibule
- •2.2.2 Respiratory Mucosa
- •2.2.3 Olfactory Mucosa
- •Supporting Cells
- •Basal Cell
- •Olfactory Receptor Cell (Bipolar Neuron)
- •Brush Cell (Microvillar Cell)
- •2.2.3.2 The Lamina Propria
- •2.2.3.3 Olfactory Glands (Bowman’s Glands)
- •2.3 Paranasal Sinuses
- •2.4 Pharynx
- •2.5 Larynx
- •2.6 Trachea
- •2.6.1.1 Ciliated Columnar Cells
- •2.6.1.2 Goblet Cells
- •2.6.1.3 Brush Cells
- •2.6.1.4 Basal Cells
- •2.6.1.5 Enteroendocrine System Cells (Kulchitsky Cells or DNES Cells)
- •2.6.2 Lamina Propria
- •2.7 Lungs
- •2.7.1 Pleura
- •2.7.2 Bronchi
- •2.7.3 Bronchioles
- •2.7.3.1 Terminal Bronchioles
- •2.7.3.2 Respiratory Bronchioles
- •2.7.4 Ductus Alveolaris
- •2.7.5 Alveoli
- •2.7.5.2 Type II Alveolar Cell (Septal Cell, Large Alveolar Cell)
- •References
- •3.1.1.3 Nerves
- •Ophthalmic Division
- •Maxillary Division
- •Parasympathetic Nerve Supply
- •3.1.1.4 Bony Anatomy
- •3.1.1.5 Cartilaginous Pyramid
- •3.1.1.6 Structure
- •External Nasal Anatomy
- •Internal Nasal Anatomy
- •3.1.2 Nasal Physiology
- •3.1.2.1 Nasal Airflow
- •3.1.2.2 Abnormal Nasal Physiology
- •3.2.1 Larynx Anatomy
- •Cricoid Cartilage
- •Thyroid Cartilage
- •Epiglottis
- •Arytenoid Cartilages
- •Corniculate Cartilages
- •Cuneiform Cartilages
- •Extrinsic Ligaments
- •Intrinsic Ligaments
- •Laryngeal Cavity
- •Piriform Recesses
- •Cricothyroid Muscles
- •Posterior Cricoarytenoid Muscles
- •Lateral Cricoarytenoid Muscles
- •Transverse Arytenoid Muscle
- •Thyroarytenoid Muscles
- •Superior Laryngeal Nerve
- •Arteries
- •Veins
- •Lymphatics
- •Swallowing
- •Respiration
- •Phonation
- •3.2.2.1 Reflex Glottic Closure
- •References
- •4.1 Introduction
- •4.2.1 Choanal Atresia
- •4.2.2 Pyriform Aperture Stenosis
- •4.2.3 Cleft Lip Nasal Deformity
- •4.2.4 Nasolacrimal Duct Cysts
- •4.2.5 Encephaloceles
- •4.3 Craniofacial Anomalies
- •4.3.1 Pierre Robin Syndrome
- •4.3.2 Treacher-Collins Syndrome
- •4.3.3 Crouzon Syndrome
- •4.3.4 Down Syndrome
- •4.3.5 Apert Syndrome
- •4.4.1 Thyroglossal Duct Cyst
- •4.4.2 Laryngomalacia
- •4.4.3 Vocal Fold Paralysis
- •4.4.5 Subglottic Stenosis
- •4.4.6 Subglottic Hemangioma
- •4.4.7 Laryngeal Cysts
- •4.4.8 Laryngeal Cleft
- •4.5 Conclusion
- •References
- •5.1 Innate Immunity
- •5.2 Adaptive Immunity
- •References
- •6.1 Introduction
- •6.2 Innate Immunity
- •6.3 Adaptive Immunity
- •References
- •7.1 Introduction
- •References
- •8: Respiratory Microbiome
- •8.1 Introduction
- •8.2.1 Childhood Asthma
- •8.2.2 Asthma Exacerbation
- •8.3 Bacteriome
- •8.4 Virome
- •8.5 Mycobiome
- •References
- •9.1 Introduction
- •References
- •10.1 Introduction
- •10.3.3 The Appointment Process, Explained
- •10.3.5 Parental Involvement
- •10.4 Coordinating Care When Your Child Is Ill
- •10.4.3 Exhibit Cohesion
- •10.6 Conclusion
- •References
- •11.1 Introduction
- •11.2 Nasal Cavity
- •11.2.1 Choanal Atresia
- •11.2.2 Rhinosinusitis
- •11.2.4 Juvenile Nasopharyngeal Angiofibroma
- •11.3 Pharynx
- •11.4 Nasopharynx
- •11.4.1 Adenoid Hypertrophy
- •11.4.2 Nasopharyngeal Carcinoma
- •11.5 Oropharynx
- •11.5.1 Thyroglossal Duct Cyst
- •11.6 Hypopharynx
- •11.6.1 Retropharyngeal Abscess
- •11.6.2 Lymphatic Malformation
- •11.6.4 Lymphoma
- •11.6.5 Rhabdomyosarcoma
- •11.7 Larynx
- •11.7.1 Subglottic Stenosis
- •11.7.2 Laryngotracheal Papillomatozis
- •11.7.3 Croup
- •11.7.4 Epiglottitis
- •11.7.5 Foreign Body Aspiration
- •References
- •12.2.1 Plain Radiography
- •12.2.1.1 The Thymus
- •Tracheal Buckling
- •Hilum
- •Diaphragm
- •Mediastinal Borders
- •Lung Opacities
- •Cystic Lung Diseases
- •Pulmonary İnterstitial Emphysema (PIE)
- •Unilateral Hyperlucent Lung
- •12.2.2 Fluoroscopy
- •12.2.3 Ultrasound
- •12.2.4 Computed Tomography
- •12.2.5 Magnetic Resonance Imaging (MRI)
- •12.2.6 Angiography
- •12.2.7 Positron Emission Tomography (PET)
- •12.3 Conclusion
- •References
- •13.1 Introduction
- •13.2 Nasal Diagnostic Procedures
- •13.2.1 Indications
- •13.2.2 Contraindications
- •13.2.3 Anatomical Features
- •13.2.4 Technical Considerations
- •13.2.5 Technique
- •13.2.5.1 First Pass
- •13.2.5.2 Second Pass
- •13.2.5.3 Third Pass
- •13.3 Flexible Laryngoscopy
- •13.4 Direct Laryngoscopy
- •13.5 Video Laryngoscopy
- •13.5.1 Indications
- •13.5.2 Contraindications
- •13.5.3 Outcomes
- •13.5.4 Equipment
- •13.5.5 Approach Considerations
- •References
- •14.1 Upper Airways
- •14.2.3 Laryngeal Pathologıes
- •References
- •15.1 Introduction
- •15.2 Airway Measurements
- •References
- •16.1 Introduction
- •16.2 Background
- •References
- •17: Allergen Testing: Purpose, Procedure, Interpretation
- •17.1 Introduction
- •17.2 Tests
- •17.2.1 Skin Tests
- •17.2.3 Component Resolved Diagnosis (CRD)
- •17.2.4 Tryptase
- •17.2.5 Basophil Activation Test (BAT)
- •17.2.6 Provocation Tests
- •17.2.7 Nasal sIgE
- •17.2.8 Nasal Smear Eosinophilia
- •17.2.9 Eosinophilic Cationic Protein (ECP)
- •References
- •18: Smell Testing: Purpose, Procedure, Interpretation
- •18.1 Introduction
- •18.2 Possible Olfactory Disorder Diagnosis
- •18.2.1 Conductive Defects
- •18.2.3 Inherited Disorders
- •18.2.3.1 Hormonal Disturbances
- •18.4 Odor Threshold Tests
- •18.8.1 Butanol Threshold Test
- •18.8.1.1 The Penn State University Odor Identification Exam
- •18.8.2 Cross-Cultural Smell Identification Test
- •18.8.3 Sniffin’ Sticks
- •References
- •19: Taste Testing: Purpose, Procedure, Interpretation
- •19.1 Introduction
- •19.2 Definitions
- •19.2.1 Taste Dysfunction Abnormalities
- •19.4.1 Taste Dysfunction
- •19.4.2 COVID-19
- •19.5 Taste Disorder Diagnosis
- •19.6.2 Magnitude Matching
- •19.6.3 Spatial Test
- •References
- •20.1 Introduction
- •20.2 Primary Otalgia Causes
- •20.2.1 Auricle
- •20.2.1.1 Infections
- •20.2.1.2 Trauma
- •20.2.1.3 Allergic Angioedema
- •20.2.1.4 Thermal Damage
- •20.2.2 External Auditory Canal
- •20.2.2.1 Otitis Externa
- •20.2.2.2 Malignant Otitis Externa
- •20.2.2.3 Eczematous Dermatitis
- •20.2.2.4 Furunculosis
- •20.2.2.5 Foreign Body
- •20.2.2.6 Cerumen Impaction
- •20.2.2.7 Tumors
- •20.2.3 Middle Ear
- •20.2.3.1 Acute Otitis Media
- •20.2.3.3 Eustachian Tube Dysfunction
- •20.2.3.4 Cholesteatoma
- •20.2.3.5 Trauma
- •20.3 Secondary Otalgia Causes
- •20.3.1 Oropharyngeal Infections
- •20.3.2 Dental Causes
- •20.3.3 Auricular Lymphadenitis
- •20.3.4 Neck Abscess
- •20.3.5 Parotitis
- •20.3.6 Temporomandibular Joint Dysfunction
- •20.3.7 Sinusitis
- •20.4 Differential Diagnosis
- •References
- •21.1 Introduction
- •21.2 Bacterial Otitis Externa
- •21.3 Acute Otitis Media
- •21.4 Chronic Suppurative Otitis Media
- •21.5 Foreign Body
- •21.5.1 Cerumen
- •21.5.2 Tympanostomy Tube Drainage
- •21.5.3 Traumatic Cerebrospinal Fluid Otorrhea
- •21.5.5 Necrotizing Otitis Externa (Malignant External Otitis)
- •21.5.6 Neoplasms
- •21.5.7 Polyps
- •21.5.8 Otomycosis
- •21.5.9 First Branchial Cleft Cysts
- •21.5.10 Cholesteatoma
- •21.5.11 Spontaneous Cerebral Spinal Fluid Otorrhea
- •References
- •22.1 Introduction
- •22.4 Congenital Causes
- •22.4.1 Choanal Atresia
- •22.4.2 Pyriform Apertura Stenosis
- •22.4.3 Nasal Midline Congenital Masses
- •22.4.3.1 Nasal Dermoid Cyst
- •22.4.3.2 Nasal Glioma
- •22.4.3.3 Encephalocele (Encephalo-Meningocele)
- •Differential Diagnosis
- •22.4.3.4 Nasolacrimal Duct Cyst (Dacryocystocele)
- •22.5 Infectious Causes
- •22.5.1.1 Rhinitis Etiology
- •22.5.2 Neonatal Rhinitis
- •22.5.3 Bacterial or Viral Rhinitis
- •22.5.4 Iatrogenic Rhinitis
- •22.5.5 Infectious Rhinitis (Rhinosinusitis)
- •22.6 Adenoid Hypertrophy
- •22.7 Inflammatory Causes
- •22.7.1 Allergic Rhinitis
- •22.7.2 Nonallergic Rhinitis
- •22.7.3 Eosinophilic Nonallergic Rhinitis (NARES)
- •22.7.4 Nasal Polyp
- •22.7.5 Antrochoanal Polyp
- •22.7.6 Inferior Turbinate Hypertrophy
- •22.8 Neoplasia
- •22.8.1 Benign Tumors (Juvenile Nasopharyngeal Angiofibroma)
- •22.8.2 Malignant Tumors
- •22.9 Systemic Causes
- •22.9.1 Cystic Fibrosis
- •22.9.2 Primary Ciliary Dyskinesia
- •22.10 Trauma/Iatrogenic Causes
- •22.10.1 Nasal Trauma-Septal Hematoma
- •22.10.2 Septum Deviation
- •22.10.3 Nasal Foreign Bodies
- •References
- •23.1 Introduction
- •23.2 Pathophysiology
- •23.3 Allergic Rhinitis
- •23.4 Non-allergic Rhinitis
- •23.5 Infectious Rhinitis
- •23.6.1 Vasomotor Rhinitis
- •23.7 Evaluation
- •23.8 Diagnosis
- •23.9 Treatment
- •23.10 Prognosis
- •23.11 Conclusion
- •References
- •24.1 Introduction
- •24.2 Pathogenesis
- •24.3 Diagnosis
- •24.3.1 History
- •24.3.2 Examination
- •24.4 Differential Diagnoses
- •24.5 CSF Rhinorrhea
- •24.5.1 CSF Physiology
- •24.5.1.1 Pathogenesis
- •24.6 Diagnosis
- •24.6.1 Chemical Diagnosis
- •24.6.2 Imaging Diagnosis
- •24.7 Treatment
- •24.7.1 Surgical Technique
- •References
- •25.1 Introduction
- •25.1.1 Waldeyer Ring
- •25.3 Anatomy
- •25.3.1 Lymphatic Drainage
- •25.3.1.1 Nerve Supply
- •25.6 Tonsillary Hypertrophy
- •25.7 Physical Examination
- •25.8.1 Obstructive Sleep Apnea
- •References
- •26.1 Introduction
- •26.5 Halitosis Physiopathology
- •26.6.1 Oral Halitosis (Intraoral Halitosis, Oral Malodor)
- •26.6.1.1 Periodontal Infections
- •26.6.1.2 Tongue Oriented Halitosis
- •26.6.1.3 Peritonsillar Abscess
- •26.7 Paranasal Sinus Diseases
- •26.8 Adenoid Vegetation
- •26.9 Chronic Pharyngitis
- •26.10 Chronic Tonsillitis
- •26.11 Tonsillolith
- •26.12 Non-Oral Halitosis
- •26.13 Gastroesophageal Reflux
- •26.14 Diagnosis
- •26.14.1 Organoleptic Measurement
- •26.14.2 Sulfur Monitoring
- •26.14.2.1 Indirect Methods
- •26.14.2.3 Ammonia Monitoring
- •26.14.2.4 Polymerase Chain Reaction (PCR)
- •26.15 Physical Examination
- •References
- •27.1 Introduction
- •27.2 Epidemiology
- •27.4 Diagnosis
- •27.5.1 Clinical Assessment
- •27.6 Treatment
- •27.6.1 Voice Therapy
- •27.7 Phonosurgery
- •References
- •28.1 Introduction
- •28.2 Epidemiologic Characteristics
- •28.3 Swallowing Physiologic Phases
- •28.3.1.1 Prematurity
- •28.3.1.2 Neuromuscular
- •28.3.1.5 Cardiopulmonary Disease
- •28.4 Symptoms
- •28.5 Clinical Feeding Assessment
- •28.7 Flexible Endoscopic Swallowing Evaluation
- •28.8 Imaging
- •28.9 Endoscopic Assessments
- •28.9.1 High-Resolution Manometry
- •28.10 Medical Management
- •28.11 Surgical Management
- •28.11.1 Ankyloglossia
- •28.11.2 Laryngomalacia
- •28.11.3 Laryngeal Cleft
- •28.12 Conclusions
- •References
- •29.1 Introduction
- •29.2 Reactive Lymph Node Enlargements
- •29.3 Vaccines
- •29.4 Acute Suppurative Lymphadenitis
- •29.6 Granulomatous Lymphadenitis
- •29.6.1 Mycobacterial Infection
- •29.6.2 BCG Vaccine
- •29.6.3 Cat-Scratch Disease
- •29.6.4 Sarcoidosis
- •29.6.5 Kikuchi-Fujimoto Disease
- •29.7 Malignancies
- •29.8 Diagnosis
- •References
- •30.1 Introduction
- •30.2 Upper Airway Cough Syndrome
- •30.3 Chronic Rhinosinusitis
- •30.5 Otogenic Cough
- •30.6 Laryngeal Clefts
- •30.7 Conclusion
- •References
- •31.1 Introduction
- •31.5.1 Vocal Cord Disfunction (VCD)
- •31.5.2 Obstructive Sleep Apnea Syndrome (OSAS)
- •31.5.3 Allergic or Non-Allergic Rhinitis
- •31.6 Conclusion
- •References
- •32.1 Introduction
- •32.2.1 Non-massive Hemoptysis
- •32.2.2 Massive Hemoptysis
- •32.4 Diagnostic Evaluation
- •32.4.1 History
- •32.4.1.1 Infection Warning Signs
- •32.4.1.2 Choking
- •32.4.1.3 Exposures
- •32.4.1.4 Underlying Medical Problems
- •32.4.2 Physical Examination
- •32.4.3 Laboratory Evaluation
- •32.4.4 Imaging
- •32.5.1 Respiratory Illness
- •32.5.3 Trauma
- •32.5.4 Hemoptysis Mimics
- •References
- •33.1 Introduction
- •33.6 Conclusion
- •References
- •34: Pediatric Allergic Rhinitis: Otolaryngology Perspective
- •34.1 Introduction
- •34.2 Epidemiology
- •34.2.1 Prevalence
- •34.2.2 Risk factors
- •34.3.1 Classical Pathway
- •34.3.2 Nasal Pathway
- •34.4.2 Physical Examination
- •34.4.3 Diagnostic Tests
- •34.4.4 Nasal Cytology
- •34.4.5 Imaging
- •34.5.1 Adenoid Hypertrophy
- •34.5.2 Nasal Septal Deviation
- •34.5.3 Chronic Rhinosinusitis
- •34.5.4 Turbinate Hypertrophy
- •34.5.5 Nasal Foreign Body
- •34.5.6 Other Clinical Conditions
- •34.6.1 Saline Irrigation (Douching)
- •34.7 Treatment
- •34.7.1 Oral Antihistamines
- •34.7.2 Intranasal Steroids
- •34.7.3 Leukotriene Inhibitors
- •34.7.5 Oral Steroids
- •34.7.6 Intranasal Antihistamines
- •34.7.7 Immunotherapy (Sublingual-Subcutaneous)
- •34.8 Conclusion
- •References
- •35: Allergic Rhinitis: Pediatric Pulmonologist Perspective
- •35.1 Introduction
- •35.2.1 Epidemiological Relationship
- •35.2.4 Immunopathology
- •35.2.7 Non-pharmaceutical Treatment Method
- •35.2.8 Pharmaceutical Medication Policy
- •35.2.9 Immunotherapy Against Allergens
- •35.6 Conclusion
- •References
- •References
- •37.1 Introduction
- •37.2 Adenoid Hypertrophy
- •37.7 Preoperative Evaluation
- •37.8 Contraindications
- •37.9 Complications
- •37.9.1 Bleeding
- •37.9.2 Hypernasality
- •37.9.3 Surgical Traumas
- •37.9.4 Torticollis
- •37.9.5 Otitis Media
- •37.9.6 Psychological Trauma
- •37.9.7 Nasopharyngeal Stenosis
- •37.9.8 Recurrence
- •37.10 Postoperative Care
- •37.11 Surgery
- •37.12.1 Adenoiditis
- •References
- •38.1 Introduction
- •38.2 Anatomy
- •38.2.1 Palatine Tonsils (Faucial Tonsils)
- •38.2.2 Lingual Tonsil
- •38.2.3 Adenoids (Pharyngeal Tonsil)
- •38.2.4 Tubal Tonsils
- •38.5.1 Viral Tonsillitis
- •38.5.2 Bacterial Tonsillitis
- •38.5.3 Candida
- •38.6.1 Suppurative Complications
- •38.6.1.1 Peritonsillar Abscess (Quincy Tonsil)
- •Lemierre’s Syndrome
- •38.6.2 Nonsuppurative Complications
- •38.6.2.1 Acute Rheumatic Fever
- •38.6.2.2 Poststreptococcal Glomerulonephritis
- •38.6.2.3 Scarlet Fever
- •38.6.2.6 Palmoplantar Pustulosis (PPP)
- •38.6.2.7 IgA Nephropathy
- •38.7 Clinical Manifestation
- •38.7.1 Infection
- •38.7.2 Obstruction
- •38.7.3 Neoplasia
- •38.8 Diagnosis
- •38.8.2 Physical Examination
- •38.8.3 Laboratory
- •38.8.4 Imagining
- •38.8.5 Polysomnography
- •38.9 Treatments
- •38.9.1 Medical Treatment
- •38.9.2 Surgery
- •38.9.2.2 Tonsillectomy
- •38.9.3.1 Intraoperative Complications
- •38.9.3.4 Postoperative Long-Term Complications (>weeks)

20 Otalgia inChildren
Table 20.1 Symptoms and examination ndings consistent with the clinical diagnosis causing
otalgia in children
Symptoms and examination
ndings/clinical diagnosis
Primary otalgia
Auricle
Infection (perichondritis,
cellulitis, H. zoster)
Trauma x/xx/
Allergic angioedema x/xx
Thermal damage x/xx/
External auditory canal
Otitis externa x/xx
Malignant Otitis externa xxx
Eczematous dermatitis x/xx
Furunculosis x/xx
Foreign body x/xx
Cerumen impaction x
Tumors xx/xxx
Middle ear
Acute otitis media xx/xxx +
Otitis media with effusion
Eustachian tube dysfunction x
Cholesteatoma x/xx
Trauma x/xx/
Secondary otalgia
Oropharyngeal infections x/xx +
Dental causes x/xx
Auricular lymphadenitis x
Neck abscess x/xx +
Parotitis x/xx
Temporomandibular joint
dysfunction
Sinusitis x
Otalgia severity x:mild, xx:moderate, xxx:severe; + presence; − absence
Otalgia Fever Otorrhea
xx
xxx
xxx
x/− − −
xxx
x
+/− − −
− − −
− − − −
− − − −
+
+/−
+ +
+/−
− − −
− − − −
− +/− +/− −
− − +/− −
+
−
+/− +/−
− − +/−
− +/−
− +/− +/−
− −
+/− − −
+/− − − −
− −
+/− − − −
− − −
+/− − −
Hearing
Loss
−
+/− −
+
+
Other symptoms and
ndings
Itching
Bleeding
Itching, tragal
tenderness
−
Itching
Restlessness,
vomiting, headache
−
Tinnitus
−
Rhinorrea, vertigo,
tinnitus
Dysphagy, sore throat
Toothache
Swelling, hyperemia
Difculty chewing,
clicking sound,
malocclusion
Nasal congestion,
cough, nasal
discharge
273

274
Table 20.2 Presence of examination, laboratory, and radiological ndings consistent with the
clinical diagnosis causing otalgia in children
Otoscopic
Examination ndings/
clinical diagnosis
Primary otalgia
Auricle
Infection (perichondritis,
cellulitis, H. zoster)
Trauma +
Allergic angioedema +
Thermal damage +
External auditory canal
Otitis externa
Malignant Otitis externa
Eczematous dermatitis + +
Furunculosis + +
Foreign body
Cerumen impaction
Tumors
Middle ear
Acute otitis media
Otitis media with
effusion
Eustachian tube
dysfunction
Cholesteatoma
Trauma + +
Secondary otalgia
Oropharyngeal infections +
Dental causes
Auricular lymphadenitis +
Neck abscess +
Parotitis +
Temporomandibular joint
dysfunction
Sinusitis
Inspection
ndings
+
+/−
+/−
+/−
−
+/−
−
−
−
−
+/− − +/−
+/− − − +/−
− − +/− +/−
examination
ndings
+/− +/− −
+/− − +/−
− − −
+/− − −
+
+ + +
+
+
+
+ +
+
+
+
−
− +/− −
−
− +/− −
Laboratory
ndings
− −
− −
+/− −
− −
− −
+/−
− +/−
− −
−
−
+
+ +
Y. Yüksel et al.
Radiological
ndings (CT/
MR)
+
+/−
+
+
−
+
References
1. Earwood JS, Rogers TS, Rathjen NA.Ear pain: diagnosing common and uncommon cause.
Am Fam Physician. 2018;97(1):20–7.
2. Harrison E, Cronin M.Otalgia. Aust Fam Physician. 2016;45(7):493–7.
3. Majumdar S, Wu K, Bateman ND, Ray J.Diagnosis and management of otalgia in children.
Arch Dis Child Educ Pract Ed. 2009;94:33–6.
4. Greenes D, Neuman MI, Wiley JF.Evaluation of earache in children. 2023. www.uptodate.com.
5. Kansu L, Yılmaz I.Herpes zoster oticus (Ramsay Hunt syndrome) in children: case report and
literature review. Int J Pediatr Otorhinolaryngol. 2012;76:772.

20 Otalgia inChildren
6. Leung AKC, Fong JHS, Leong AG.Otalgia in children. U Natl Med Assoc. 2000;92:254–60.
7. Rosenfeld RM, Schwartz SR, Cannon CR, et al. Clinical practice guideline: acute otitis
externa. Otolaryngol Head Neck Surg. 2014;150:S1–S24.
8. Neilan RE, Roland PS.Otalgia. Med Clin North Am. 2010;94(5):961–71.
9. Jamal A, Alsabea A, Tarakmeh M, Safar A.Etiology, diagnosis, complications, and management of acute otitis media in children. Cureus. 2022;14(8):e28019.
10. Büyükcam A, Kara A, Bedir T, Gülhan B, Özdemir H, Sütçü M, etal. Pediatricians’ attitudes
in management of acute otitis media and ear pain in Turkey. Int J Pediatr Otorhinolaryngol.
2018;107:14–20.
11. Lieberthal AS, Carroll AE, Chonmaitree T, etal. The diagnosis and management of acute otitis
media. Pediatrics. 2013;131:e964.
12. Makuszewska M.Classication, diagnosis and treatment of Eustachian tube dysfunction–literature review. Polish Otorhinolaryngol Rev. 2021;10(4):22–8.
13. Levenson MJ, Parisier SC, Chute P, Wenig S, Juarbe C.A review of twenty congenital cholesteatomas of the middle ear in children. Otolaryngol Head Neck Surg. 1986;94(5):560–7.
14. Fontes Lima A, Carvalho Moreira F, Sousa Menezes A, Esteves Costa I, Azevedo C, Sá Breda
M, Dias L.Is pediatric cholesteatoma more aggressive in children than in adults? A comparative
study using the EAONO/JOS classication. Int J Pediatr Otorhinolaryngol. 2020;138:110170.
15. Hurtado TR, Zeger WG.Hemotympanums secondary to spontaneous epistaxis in a 7-year-old.
J Emerg Med. 2004;26:61.
16. Conover K.Earache. Emerg Med Clin North Am. 2013;31:413.
17. Vicedomini D, Lalinga G, Lugli N, D’Avino A.Diagnosis and management of acute pharyngotonsillitis in the primary care pediatrician’s ofce. Minerva Pediatr. 2014;66(1):69–76.
18. Ely JW, Hansen MR, Clark EC.Diagnosis of ear pain. Am Fam Physician. 2008;77(5):621–8.
19. Erbaş İC, Özlü C, Asrak HK, Güzin AÇ, Belet N.Deep neck infections in childhood. J Pediatr
Inf. 2021;15(1):38–43.
20. Battle S, Laudenbach J, Maguire JH.Inuenza parotitis: a case from the 2004 to 2005 vaccine
shortage. Am J Med Sci. 2007;333:215.
21. Francis CL, Larsen CG.Pediatric sialadenitis. Otolaryngol Clin N Am. 2014;47:763.
22. Stong BC, Sipp JA, Sobol SE.Pediatric parotitis: a 5-year review at a tertiary care pediatric
institution. Int J Pediatr Otorhinolaryngol. 2006;70:541.
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Otorrhea inChildren
21
YavuzSultanSelimYıldırım, NurayBayar Muluk,
andChae-SeoRhee
21.1 Introduction
Otorrhea refers to the discharge of uid from the ear. It can occur due to issues in
the external ear canal or middle ear problems involving a perforation in the tympanic membrane (TM). To discern the primary reasons behind otorrhea in children,
a thorough examination and medical history are essential. The majority of children
experiencing otorrhea are typically diagnosed with bacterial otitis externa or acute
otitis media (AOM) featuring a perforated tympanic membrane. Also, button batteries require emergent removal because pressure necrosis and/or severe burns from
residual electric current or leakage of caustic contents may rapidly lead to extensive
damage to adjacent structures [1]. Patients who appear unwell or exhibit otorrhea
following head trauma necessitate immediate and thorough efforts to diagnose and
address potential life-threatening factors contributing to otorrhea, such as basilar
skull fractures, necrotizing otitis externa, or infectious complications associated
with acute otitis media.
Otorrhea presents a common challenge for otolaryngologists, with its causes
ranging from relatively harmless to severe and life-threatening conditions.
Consequently, an accurate determination of the underlying cause becomes paramount in establishing an effective treatment plan. In this discussion, we will focus
Y. S. S. Yıldırım
Clinic of Otorhinolaryngology, Elazig Fethi Sekin City Hospital, Elazig, Turkey
N. Bayar Muluk (*)
Department of Otorhinolaryngology, Faculty of Medicine, Kırıkkale University,
Kırıkkale, Turkey
C.-S. Rhee
Department of Otorhinolaryngology, Head and Neck Surgery, College of Medicine, Seoul
National University, Seoul, South Korea
e-mail: csrhee@snu.ac.kr
© The Author(s), under exclusive license to Springer Nature
Switzerland AG 2024
H. Yüksel et al. (eds.), Pediatric Airway Diseases, Comprehensive ENT,
https://doi.org/10.1007/978-3-031-74853-0_21
277

278
on the most prevalent causes of otorrhea in children and provide guidance on decision-making for management based on a precise diagnosis.
Y. S. S. Yıldırım et al.
21.2 Bacterial Otitis Externa
Acute otitis externa is a common condition characterized by inammation of the ear
canal. Bacterial infection, primarily driven by Pseudomonas aeruginosa and
Staphylococcus aureus, is the main cause of the acute form. It manifests with the
sudden onset of inammation in the ear canal, leading to symptoms like ear pain,
itching, swelling of the canal, redness, and discharge. Often, this condition arises
after activities like swimming or minor injuries resulting from improper cleaning. A
characteristic sign is tenderness when moving the tragus or pinna.
Upon examination, you will observe an ear canal that appears red, swollen, and
contains cellular debris. Importantly, external otitis does not necessarily involve the
middle ear, so there may not be any middle ear uid buildup or a purulent middle
ear infection. When visible, the eardrum (tympanic membrane or TM) typically
exhibits redness or debris. In some cases, the swollen canal can make it challenging
to see the eardrum clearly. The discharge is usually purulent, ranging from white to
yellow and may dry to form a crust.
For uncomplicated cases, the preferred treatment options include topical
antimicrobials or antibiotics like acetic acid, aminoglycosides, polymyxin B,
and quinolones. These medications are available in formulations with or without
topical corticosteroids, and the addition of corticosteroids can help expedite
symptom relief. Oral antibiotics are reserved for situations where the infection
has spread beyond the ear canal or in patients at risk of a rapidly worsening
infection [2, 3].
21.3 Acute Otitis Media
Acute Otitis Media (AOM) is an infection of the middle ear, which can be caused by
viruses and/or bacteria. It stands as the most common childhood infection for which
antibiotics are prescribed in the United States. On occasion, during an episode of
acute otitis media, the eardrum may rupture. This is often accompanied by ear pain
and a relatively short-lived fever, followed by relief from pain coinciding with the
onset of ear discharge. The drainage typically appears clear or white. The perforation may have healed by the time the patient seeks medical attention, but the discharge may persist for some time, especially if external otitis has developed.
Frequently, the perforation itself may not be visible during ear examination
(otoscopy) due to the ear discharge obstructing the view of the tympanic membrane
(TM). Alternatively, the perforation may have healed rapidly, as shown in Fig.21.1.
When it is visible, the TM typically exhibits an abnormal appearance and lacks
mobility when assessed with pneumatic otoscopy. If the perforation is of recent
origin, it generally heals spontaneously once the infection resolves [4, 5].

21 Otorrhea inChildren
Fig. 21.1 Endoscopic
view of suppurated acute
otitis media
21.4 Chronic Suppurative Otitis Media
279
Chronic suppurative otitis media (CSOM), or mastoiditis, is an eardrum perforation
with chronic drainage from the middle ear cleft [5]. This condition is more frequently seen in children who lack access to health care and, thus, do not have timely
diagnosis and treatment of acute otitis media. It should not be confused with longstanding otitis media with effusion (OME, or “serous” otitis media) or persistent
acute otitis media, which involve an intact tympanic membrane and no drainage.
CSOM is often painless. On examination, a debris-lled canal is noted. The discharge is often white to yellow and mixed with soft cerumen. Pseudomonas aeruginosa and Staphylococcus aureus are common pathogens. Treatment typically
consists of topical antibiotic ear drops, with topical quinolones being the beststudied treatment choice. Parenteral antibiotic administration guided by culture of
the ear discharge and/or tympanomastoidectomy may be necessary in refractory
cases, though the evidence for the superiority of systemic antibiotics over topical
quinolone antibiotics is mixed and not convincing [5, 6].
21.5 Foreign Body
The primary foreign objects encountered in cases are usually food, plastic toys, and
small household objects. Identifying these cases can be challenging due to the often
unnoticed nature of the incident, non-specic symptoms, and frequent initial misdiagnosis. In the majority of instances involving foreign objects lodged in the ear or

280
Y. S. S. Yıldırım et al.
nose, a trained physician can safely extract them within an ofce setting with minimal risk of complications. Typical removal techniques comprise the use of forceps,
water irrigation, and suction catheters. Typical foreign bodies include:
• Toys or small objects placed in the ear by toddlers or placed into younger sib-
ling’s ears
• Insects, although they are often so irritating that removal occurs before otorrhea
develops
• Food material, especially nuts with irritating oils that can cause a signicant
reaction
• Button batteries (often used in small electronic devices such as hearing aids)
• Expelled tympanostomy tube with granulation tissue and bloody otorrhea
Button batteries require emergent removal because pressure necrosis and/or
severe burns from residual electric current or leakage of caustic contents may rapidly lead to extensive damage to adjacent structures [1].
Otoscopy serves as a diagnostic tool. However, the presence of either cerumen
buildup or otorrhea may obstruct the visibility of the foreign body, necessitating
cleaning before the object becomes visible (as depicted in Fig.21.2). In cases where
ear foreign bodies are present and do not lead to otorrhea, straightforward techniques can typically be employed for removal within an outpatient environment.
However, if removal in the outpatient setting is not feasible, the foreign body should
be extracted in an operating room while the patient is under sedation or general
anesthesia. The initial attempt at removal is of paramount importance since the success rates signicantly decrease after the rst unsuccessful attempt. Consequently,
Fig. 21.2 Endoscopic
view of foreign body in
external ear canal

21 Otorrhea inChildren
281
complications are more likely to arise as the number of failed removal attempts
increases. These removal attempts can often be painful, lead to bleeding that limits
visibility, and potentially push the foreign body further into the ear canal.
21.5.1 Cerumen
Annoying to many parents but generally harmless, some children have thin
cerumen that can present as ear drainage. In general, cerumen is only a problem
if it is impacted or precludes eardrum examination. Removal may be necessary
in such cases, but precautions should be taken when instrumenting the ear
canal [7].
21.5.2 Tympanostomy Tube Drainage
About 10–30% of children with tympanostomy tubes will have at least one episode
of acute otorrhea while their tympanostomy tubes are in place immediately postoperatively or during an episode of acute otitis media (Fig.21.3). The drainage is usually foul-smelling, mucoid, and may be mixed with blood. It is generally treated
with antibiotic drops. Suction cleaning of the ear canal may be needed for slides to
be effective. Rarely, systemic antibiotics or even mastoid surgery is required if the
drainage is persistent.
In a patient with a history of trauma or compromised immune system, the presence of otorrhea can be a sign of a critical and potentially life-threatening condition.
Fig. 21.3 Endoscopic
view of infected ventilation
tube with mucoid
discharge

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Y. S. S. Yıldırım et al.
21.5.3 Traumatic Cerebrospinal Fluid Otorrhea
Trauma to the temporal bone can lead to immediate leaks through the fracture line
or delayed leaks caused by obstructions in the cochlear aqueduct, typically due to
soft tissue or bone. The presence of cerebrospinal uid (CSF) otorrhea is a signicant concern following head trauma. If there is any discharge from the ear noticed
after a severe head injury, especially if it is clear or contains blood, it is essential to
evaluate the patient for CSF otorrhea, which can originate from a basilar temporal
skull fracture. Additionally, hemorrhagic otorrhea may result from middle ear
trauma caused by a direct ear impact, auditory barotrauma, or the insertion of a
foreign object into the external ear canal [8].
To assess the potential CSF leakage, a quick bedside test can be performed by
placing a drop of ear drainage on absorbent material like a coffee lter or paper
towel. A rapidly spreading “halo” or a ring of clear uid around the area stained
with red blood indicates a positive result. However, it is crucial to note that the halo
test does not differentiate between CSF, saline, saliva, or other clear uids and has
not undergone formal clinical validation.
As an alternative, healthcare professionals may analyze the uid coming from
the ear or nose for the presence of beta2 transferrin, a variant of the transferrin protein primarily found in cerebrospinal uid.
21.5.4 Complications ofAcute Otitis Media
The mastoid air cells are linked to the far end of the middle ear through a narrow
canal or antrum. Consequently, most instances of Acute Otitis Media (AOM)
involve some degree of inammation in the mastoid. In exceptional cases, the
mastoid infection does not resolve, leading to the development of acute mastoiditis, characterized by the accumulation of pus within the mastoid air cells. The
child with mastoiditis will have painful swelling behind the ear that typically
pushes the pinna forward.
Other infratemporal complications that occur by contiguous spread of infection include petrositis (Gradenigo syndrome with sixth nerve palsy) and
labyrinthitis.
Intracranial complications arising from Acute Otitis Media (AOM) are of
special concern when dealing with children who exhibit signs of illness. These
complications can encompass conditions such as “meningitis, epidural abscess,
brain abscess, lateral sinus thrombosis, cavernous sinus thrombosis, subdural
empyema, and carotid artery thrombosis” [9, 10]. Patients experiencing these
complications typically present with fever and gradually develop a toxic appearance. Some may also display cranial nerve decits, with cranial nerve VII (facial
nerve) being the most commonly affected, and less frequently, cranial nerve VI
[9, 10].

21 Otorrhea inChildren
283
21.5.5 Necrotizing Otitis Externa (Malignant External Otitis)
Malignant external otitis is a condition primarily affecting children who have
chronic illnesses or are immunosuppressed. Clinicians should be on the lookout for
signs such as severe and persistent ear pain, ear discharge containing Pseudomonas
aeruginosa, a signicantly elevated erythrocyte sedimentation rate, and evidence of
bone damage on a computed tomography scan, especially when dealing with these
vulnerable populations. The infection typically starts with a skin infection and can
progress to involve deeper structures like cartilage, tissue, and bone. As the infection advances, it can lead to complications such as osteomyelitis at the base of the
skull, osteomyelitis of the temporomandibular joint, the formation of brain
abscesses, and the development of generalized bacterial sepsis. Culture of the external ear canal in otorrhea is rarely helpful, as Pseudomonas species are commonly
identied with or without local infection. It is also quite difcult to obtain samples
from the middle ear that are not contaminated by external canal ora. In addition,
culture rarely changes management decisions in children with otorrhea.
Indications for culture of ear drainage include:
• Suspected necrotizing otitis externa
• Otitis media with chronic drainage, where previous treatment has failed
Patients with malignant external otitis classically present with otorrhea and
exquisite otalgia which are not responsive to topical measures used to treat simple
external otitis. The pain is generally more severe than that found in simple external
otitis, although the two may be difcult to distinguish in their early stages. The pain
in malignant external otitis tends to extend into the temporomandibular joint, resulting in pain with chewing [11].
On physical examination, purulent otorrhea is seen in more than half of cases,
and ipsilateral lower motor neuron facial nerve palsy can also be present. Granulation
tissue may be visible in the inferior portion of the external auditory canal at the
bone–cartilage junction (at the site of Santorini’s ssures). This nding may be
absent in atypical patients (e.g., HIV-infected patients and children). Early empiric
antibiotic therapy and, if needed, surgery are essential to good outcomes [12].
21.5.6 Neoplasms
Cancer is an uncommon source of otorrhea in childhood; however, it should be
taken into consideration in cases where there is abnormal tissue growth in the ear
canal or when extended treatment for external otitis does not yield the expected
results.
Ear canal cancer is a less frequent occurrence compared to cancer in the outer ear
(auricular cancer), but it tends to present with more aggressive characteristics.
During the initial stages, it may be challenging to distinguish it from external otitis.
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